Published in Infect Immun on June 01, 2004
Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science (2012) 4.17
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog (2010) 3.76
The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity (2011) 2.47
Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination. Cell Host Microbe (2015) 2.29
The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models. Nat Rev Microbiol (2010) 2.22
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog (2010) 2.17
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. J Clin Invest (2006) 2.16
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes. Nature (2014) 2.08
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature (2011) 2.04
Mucin dynamics in intestinal bacterial infection. PLoS One (2008) 1.88
IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens. J Immunol (2008) 1.66
Lymphotoxin beta receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection. Immunity (2010) 1.50
Concurrent infection with an intestinal helminth parasite impairs host resistance to enteric Citrobacter rodentium and enhances Citrobacter-induced colitis in mice. Infect Immun (2005) 1.45
Interleukin-1 receptor signaling protects mice from lethal intestinal damage caused by the attaching and effacing pathogen Citrobacter rodentium. Infect Immun (2008) 1.42
IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections. Sci Immunol (2017) 1.40
CD4+-T-cell effector functions and costimulatory requirements essential for surviving mucosal infection with Citrobacter rodentium. Infect Immun (2006) 1.38
The role of secretory antibodies in infection immunity. Nat Rev Microbiol (2010) 1.36
CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen. J Immunol (2009) 1.24
Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection. Immunity (2014) 1.14
Development of fatal colitis in FVB mice infected with Citrobacter rodentium. Infect Immun (2007) 1.14
GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol (2013) 1.12
Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38. J Biol Chem (2010) 1.12
Altering host resistance to infections through microbial transplantation. PLoS One (2011) 1.12
Intestinal mucosal responses to microbial infection. Springer Semin Immunopathol (2005) 1.10
TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol (2012) 1.07
Crucial role of the melanocortin receptor MC1R in experimental colitis. Gut (2006) 1.06
Mast cells limit systemic bacterial dissemination but not colitis in response to Citrobacter rodentium. Infect Immun (2005) 1.05
Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection. Infect Immun (2010) 1.03
IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity. Springer Semin Immunopathol (2006) 1.02
NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen. Mucosal Immunol (2013) 1.01
Resistance of chemokine receptor 6-deficient mice to Yersinia enterocolitica infection: evidence of defective M-cell formation in vivo. Am J Pathol (2008) 1.00
Vibrio cholerae: lessons for mucosal vaccine design. Expert Rev Vaccines (2011) 1.00
The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium. Infect Immun (2008) 1.00
Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen. Mucosal Immunol (2013) 0.98
Associations between mucosal innate and adaptive immune responses and resolution of diarrheal pathogen infections. Infect Immun (2009) 0.98
Modulation of acute diarrheal illness by persistent bacterial infection. Infect Immun (2008) 0.96
GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen. Cell Host Microbe (2010) 0.94
Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice. Mucosal Immunol (2011) 0.91
Fcgamma receptor regulation of Citrobacter rodentium infection. Infect Immun (2008) 0.90
Mucosal immunity to pathogenic intestinal bacteria. Nat Rev Immunol (2016) 0.90
Comparative role of immunoglobulin A in protective immunity against the Bordetellae. Infect Immun (2007) 0.90
Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis. Infect Immun (2008) 0.89
Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not. Antimicrob Agents Chemother (2012) 0.89
Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect Immun (2012) 0.89
Strain-dependent cellular immune responses in cattle following Escherichia coli O157:H7 colonization. Infect Immun (2014) 0.88
IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology. Nat Commun (2015) 0.85
A balanced IL-1β activity is required for host response to Citrobacter rodentium infection. PLoS One (2013) 0.84
The sphingosine-1-phosphate analogue FTY720 impairs mucosal immunity and clearance of the enteric pathogen Citrobacter rodentium. Infect Immun (2012) 0.83
Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen. BMC Gastroenterol (2013) 0.83
TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen. J Clin Invest (2014) 0.83
Role of Fc Receptors as a therapeutic target. Inflamm Allergy Drug Targets (2009) 0.83
White button mushrooms increase microbial diversity and accelerate the resolution of Citrobacter rodentium infection in mice. J Nutr (2013) 0.82
Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection. Elife (2015) 0.82
Regulation of virulence: the rise and fall of gastrointestinal pathogens. J Gastroenterol (2015) 0.81
THE ROLE OF SPECIFIC IgG AND COMPLEMENT IN COMBATING A PRIMARY MUCOSAL INFECTION OF THE GUT EPITHELIUM. Eur J Microbiol Immunol (Bp) (2011) 0.81
Activation of p38α in T cells regulates the intestinal host defense against attaching and effacing bacterial infections. J Immunol (2013) 0.81
Non-therapeutic administration of a model antimicrobial growth promoter modulates intestinal immune responses. Gut Pathog (2011) 0.81
DOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs. Nat Commun (2014) 0.81
Development of fatal intestinal inflammation in MyD88 deficient mice co-infected with helminth and bacterial enteropathogens. PLoS Negl Trop Dis (2014) 0.81
Dynamic changes in mucus thickness and ion secretion during Citrobacter rodentium infection and clearance. PLoS One (2013) 0.80
Citrobacter Infection and Wnt signaling. Curr Colorectal Cancer Rep (2012) 0.79
Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros. J Immunol (2014) 0.79
Re-thinking the functions of IgA(+) plasma cells. Gut Microbes (2014) 0.78
The pathogenicity of an enteric Citrobacter rodentium Infection is enhanced by deficiencies in the antioxidants selenium and vitamin E. Infect Immun (2011) 0.78
Immunization of mice with Lactobacillus casei expressing a beta-intimin fragment reduces intestinal colonization by Citrobacter rodentium. Clin Vaccine Immunol (2011) 0.78
Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation. J Crohns Colitis (2016) 0.78
Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium. Inflamm Bowel Dis (2015) 0.77
Interleukin-1 (IL-1) signaling in intestinal stromal cells controls KC/ CXCL1 secretion, which correlates with recruitment of IL-22- secreting neutrophils at early stages of Citrobacter rodentium infection. Infect Immun (2015) 0.76
Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions. Am J Physiol Cell Physiol (2014) 0.76
Steroid Receptor Coactivator 3 Contributes to Host Defense against Enteric Bacteria by Recruiting Neutrophils via Upregulation of CXCL2 Expression. J Immunol (2017) 0.75
Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice. Immunology (2015) 0.75
CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens. Biomed Res Int (2015) 0.75
Citrobacter rodentium mouse model of bacterial infection. Nat Protoc (2016) 0.75
Bile acid administration elicits an intestinal antimicrobial program and reduces the bacterial burden in two mouse models of enteric infection. Infect Immun (2017) 0.75
Citrobacter rodentium: a model enteropathogen for understanding the interplay of innate and adaptive components of type 3 immunity. Mucosal Immunol (2017) 0.75
Specialized Pro-resolving Mediators (SPM) Rescue Infant Mice from Lethal Citrobacter rodentium Infection and Promote Immunity against Re-infection. Infect Immun (2017) 0.75
Tpl2 promotes innate cell recruitment and effector T cell differentiation to limit Citrobacter rodentium burden and dissemination. Infect Immun (2017) 0.75
Diarrheagenic Escherichia coli. Clin Microbiol Rev (1998) 30.09
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature (1991) 13.19
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med (1989) 11.36
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science (1999) 6.49
Subclass restriction of murine anti-carbohydrate antibodies. J Immunol (1978) 4.99
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol (1999) 3.39
Attaching and effacing locus of a Citrobacter freundii biotype that causes transmissible murine colonic hyperplasia. Infect Immun (1993) 3.34
The eae gene of Citrobacter freundii biotype 4280 is necessary for colonization in transmissible murine colonic hyperplasia. Infect Immun (1993) 3.03
Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia. Microbes Infect (2001) 2.71
Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium. Infect Immun (1992) 2.66
Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM. J Immunol (1998) 2.52
Citrobacter rodentium infection in mice elicits a mucosal Th1 cytokine response and lesions similar to those in murine inflammatory bowel disease. Infect Immun (1999) 2.50
Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice. J Exp Med (1999) 2.24
Organogenic role of B lymphocytes in mucosal immunity. Science (1999) 2.23
Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium. Infect Immun (2003) 2.22
Exploitation of host cells by enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2000) 2.14
Transmissible murine colonic hyperplasia. Vet Pathol (1978) 2.11
The ultrastructure of transmissible murine colonic hyperplasia. Am J Pathol (1979) 2.11
The etiology of transmissible murine colonic hyperplasia. Lab Anim Sci (1976) 1.98
Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma. J Immunol (2002) 1.80
Intimin from enteropathogenic Escherichia coli restores murine virulence to a Citrobacter rodentium eaeA mutant: induction of an immunoglobulin A response to intimin and EspB. Infect Immun (1996) 1.76
A role for B cells in the development of T cell helper function in a malaria infection in mice. Proc Natl Acad Sci U S A (1998) 1.73
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infect Immun (2002) 1.73
Role of bacterial intimin in colonic hyperplasia and inflammation. Science (1999) 1.71
T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo. J Immunol (1986) 1.62
Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other Ig isotypes. J Immunol (1999) 1.61
Gene knockout B cell-deficient mice demonstrate that B cells play an important role in the initiation of T cell responses to Chlamydia trachomatis (mouse pneumonitis) lung infection. J Immunol (1998) 1.56
Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol (2000) 1.56
Central importance of immunoglobulin A in host defense against Giardia spp. Infect Immun (2002) 1.54
Citrobacter rodentium, the causative agent of transmissible murine colonic hyperplasia, exhibits clonality: synonymy of C. rodentium and mouse-pathogenic Escherichia coli. J Clin Microbiol (2000) 1.50
Citrobacter rodentium espB is necessary for signal transduction and for infection of laboratory mice. Infect Immun (1999) 1.36
Role of B cells as antigen-presenting cells in vivo revisited: antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations. Int Immunol (2001) 1.36
Antigen receptor engagement selectively induces macrophage inflammatory protein-1 alpha (MIP-1 alpha) and MIP-1 beta chemokine production in human B cells. J Immunol (1999) 1.36
Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium. Infect Immun (2001) 1.34
Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice. Infect Immun (2002) 1.29
Altered hepatic transport of immunoglobulin A in mice lacking the J chain. J Exp Med (1995) 1.24
Variable region-identical monoclonal antibodies of different IgG subclass directed to Pseudomonas aeruginosa lipopolysaccharide O-specific side chain function differently. J Infect Dis (1993) 1.24
Characterization of murine antibody response to Salmonella typhimurium by a class-specific solid-phase radioimmunoassay. Infect Immun (1981) 1.18
Diminished reproduction, failure to thrive, and altered immunologic function in a colony of T-cell receptor transgenic mice: possible role of Citrobacter rodentium. Lab Anim Sci (1998) 0.89
B cells are required for the induction of intestinal inflammatory lesions in TCRalpha-deficient mice persistently infected with Cryptosporidium parvum. J Parasitol (2000) 0.87
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell (2004) 15.82
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell (2009) 11.52
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe (2008) 11.08
Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature (2007) 8.48
Gut microbiota in health and disease. Physiol Rev (2010) 7.76
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 5.56
Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc Natl Acad Sci U S A (2004) 5.34
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science (2005) 5.25
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature (2007) 4.68
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell (2007) 4.56
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature (2012) 4.41
American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology (2006) 4.41
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci U S A (2004) 4.25
Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science (2012) 4.17
Molecular mechanisms of Escherichia coli pathogenicity. Nat Rev Microbiol (2010) 4.13
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity (2010) 3.96
The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med (2003) 3.85
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog (2010) 3.76
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun (2008) 3.68
Ulcerative colitis. Lancet (2012) 3.38
Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest (2005) 3.36
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 3.28
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci U S A (2008) 3.27
The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature (2004) 3.18
Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature (2009) 3.18
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol (2006) 3.16
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis. Proc Natl Acad Sci U S A (2002) 3.10
Manipulation of host-cell pathways by bacterial pathogens. Nature (2007) 2.89
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J (2003) 2.87
The rat genome database curators: who, what, where, why. PLoS Comput Biol (2009) 2.86
The caspase-1 inflammasome: a pilot of innate immune responses. Cell Host Microbe (2008) 2.71
Evidence of a large novel gene pool associated with prokaryotic genomic islands. PLoS Genet (2005) 2.71
Type III secretion systems and disease. Clin Microbiol Rev (2007) 2.61
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe (2007) 2.53
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol (2004) 2.51
Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia. Proc Natl Acad Sci U S A (2010) 2.46
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. Cancer Cell (2011) 2.46
The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity (2007) 2.44
Pathogenicity islands: a molecular toolbox for bacterial virulence. Cell Microbiol (2006) 2.44
Recent advances in understanding enteric pathogenic Escherichia coli. Clin Microbiol Rev (2013) 2.43
Shifting the balance: antibiotic effects on host-microbiota mutualism. Nat Rev Microbiol (2011) 2.43
Microbial pathogenesis and cytoskeletal function. Nature (2003) 2.38
Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis. Infect Immun (2005) 2.32
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice. Mol Microbiol (2003) 2.21
Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nat Rev Mol Cell Biol (2003) 2.21
Structural characterization of the molecular platform for type III secretion system assembly. Nature (2005) 2.20
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium. Infect Immun (2003) 2.17
Quorum sensing in bacterial virulence. Microbiology (2010) 2.15
IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium. Proc Natl Acad Sci U S A (2004) 2.12
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin. Nature (2008) 2.11
Human-specific regulation of alpha 2-6-linked sialic acids. J Biol Chem (2003) 2.10
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis. Gastroenterology (2008) 2.05
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system. Nat Struct Mol Biol (2009) 2.02
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proc Natl Acad Sci U S A (2004) 2.00
The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells. Cell Microbiol (2002) 2.00
An anti-infective peptide that selectively modulates the innate immune response. Nat Biotechnol (2007) 1.97
The Rat Genome Database 2013--data, tools and users. Brief Bioinform (2013) 1.94
Opposing functions of IKKbeta during acute and chronic intestinal inflammation. Proc Natl Acad Sci U S A (2008) 1.90
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis. Infect Immun (2005) 1.88
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infect Immun (2006) 1.87
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol (2005) 1.86
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains. Appl Environ Microbiol (2008) 1.84
Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut (2009) 1.83
Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications. Cell Host Microbe (2012) 1.81
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL. J Biol Chem (2004) 1.81
The role of the intestinal microbiota in enteric infection. J Physiol (2009) 1.80
Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium. Infect Immun (2002) 1.80
NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proc Natl Acad Sci U S A (2009) 1.79
Increase in expression of the copper transporter ATP7A during platinum drug-based treatment is associated with poor survival in ovarian cancer patients. Clin Cancer Res (2003) 1.79
O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem (2006) 1.79
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA. J Bacteriol (2005) 1.77
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun (2004) 1.77
Decreased shedding of Escherichia coli O157:H7 by cattle following vaccination with type III secreted proteins. Vaccine (2004) 1.77
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75
The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak. EMBO Mol Med (2012) 1.75
The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. J Biol Chem (2005) 1.74
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proc Natl Acad Sci U S A (2005) 1.73
Attaching and effacing pathogen-induced tight junction disruption in vivo. Cell Microbiol (2006) 1.73
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infect Immun (2002) 1.73
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Res (2002) 1.72
Inhaled prostacyclin is safe, effective, and affordable in patients with pulmonary hypertension, right heart dysfunction, and refractory hypoxemia after cardiothoracic surgery. J Thorac Cardiovasc Surg (2004) 1.70
Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis (2002) 1.68
RGD: a comparative genomics platform. Hum Genomics (2011) 1.68
A revised nomenclature for the human and rodent alpha-tubulin gene family. Genomics (2007) 1.68
Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network. J Immunol (2004) 1.67
Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes. Mol Microbiol (2003) 1.67