Published in Science on August 20, 2004
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Hot days induced by precipitation deficits at the global scale. Proc Natl Acad Sci U S A (2012) 2.85
Afternoon rain more likely over drier soils. Nature (2012) 1.64
Warm spring reduced carbon cycle impact of the 2012 US summer drought. Proc Natl Acad Sci U S A (2016) 1.35
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Aspects of climate change prediction relevant to crop productivity. Philos Trans R Soc Lond B Biol Sci (2005) 0.92
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Screening variability and change of soil moisture under wide-ranging climate conditions: Snow dynamics effects. Ambio (2015) 0.88
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North Atlantic salinity as a predictor of Sahel rainfall. Sci Adv (2016) 0.75
The effect of row structure on soil moisture retrieval accuracy from passive microwave data. ScientificWorldJournal (2014) 0.75
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Changes in the Asian monsoon climate during 1700-1850 induced by preindustrial cultivation. Proc Natl Acad Sci U S A (2009) 0.75
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Global consequences of land use. Science (2005) 30.19
Food security: the challenge of feeding 9 billion people. Science (2010) 22.51
Epidermal electronics. Science (2011) 8.65
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. Proc Natl Acad Sci U S A (2008) 6.59
Global hydrological cycles and world water resources. Science (2006) 5.76
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell (2009) 5.55
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Human illness from avian influenza H7N3, British Columbia. Emerg Infect Dis (2004) 4.29
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Mol Biol (2013) 4.04
Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase II study. J Clin Oncol (2006) 3.95
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U S A (2008) 3.71
Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat Med (2002) 3.54
Left atrial and right ventricular myxoma: an uncommon presentation of a rare tumour. Interact Cardiovasc Thorac Surg (2011) 3.17
Challenges in end-of-life care in the ICU. Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. Intensive Care Med (2004) 3.16
Novel avian influenza H7N3 strain outbreak, British Columbia. Emerg Infect Dis (2004) 2.90
Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. J Allergy Clin Immunol (2015) 2.82
Evidence for large decadal variability in the tropical mean radiative energy budget. Science (2002) 2.80
Impacts of climate change on the world's most exceptional ecoregions. Proc Natl Acad Sci U S A (2011) 2.66
Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation (2013) 2.64
Prognostic factors for survival in melanoma patients with brain metastases. Cancer (2010) 2.23
Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication. J Virol (2003) 2.20
Revascularisation and mortality rates following acute coronary syndromes in people with severe mental illness: comparative meta-analysis. Br J Psychiatry (2011) 2.17
An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells. Cancer Cell (2011) 2.14
The effect of recalling paracetamol on hospital admissions for poisoning in Western Australia. Med J Aust (2003) 2.11
Exploring the diversity of Gardnerella vaginalis in the genitourinary tract microbiota of monogamous couples through subtle nucleotide variation. PLoS One (2011) 2.06
Applications of beta-mixture models in bioinformatics. Bioinformatics (2005) 2.04
An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication. J Virol (2004) 1.99
Alcohol consumption and visual impairment in a rural Northern Chinese population. Ophthalmic Epidemiol (2014) 1.98
One-third of adult smokers have a mental illness. Aust N Z J Psychiatry (2009) 1.95
Genomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection. Mol Biol Cell (2009) 1.94
A functional genetic variant in microRNA-196a2 is associated with increased susceptibility of lung cancer in Chinese. Cancer Epidemiol Biomarkers Prev (2009) 1.93
Childhood-onset schizophrenia. A double-blind clozapine-haloperidol comparison. Arch Gen Psychiatry (1996) 1.92
Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1-2 trial. Lancet Oncol (2012) 1.90
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Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J Biol Chem (2005) 1.87
Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease. Blood (2009) 1.86
Multiple mechanisms of Amazonian forest biomass losses in three dynamic global vegetation models under climate change. New Phytol (2010) 1.85
Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes. Mol Cell Biol (2006) 1.85
Length of survival of patients with cancer in hospice: a retrospective analysis of patients treated at a major cancer center versus other practice settings. J Palliat Med (2007) 1.81
Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Mol Cell Proteomics (2011) 1.81
Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics. Leuk Lymphoma (2010) 1.78
miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int J Cancer (2010) 1.76
Looking for childhood-onset schizophrenia: the first 71 cases screened. J Am Acad Child Adolesc Psychiatry (1994) 1.75
MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. Oncol Rep (2010) 1.74
Speech perception for adults who use hearing aids in conjunction with cochlear implants in opposite ears. J Speech Lang Hear Res (2006) 1.74
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. Proc Natl Acad Sci U S A (2007) 1.73
The future of the global food system. Philos Trans R Soc Lond B Biol Sci (2010) 1.71
Predictors of tumor progression during neoadjuvant chemotherapy in breast cancer. J Clin Oncol (2010) 1.70
Inequitable access for mentally ill patients to some medically necessary procedures. CMAJ (2007) 1.66
Advanced dental disease in people with severe mental illness: systematic review and meta-analysis. Br J Psychiatry (2011) 1.63
Novel CACNA1S mutation causes autosomal dominant hypokalemic periodic paralysis in a Chinese family. J Mol Med (Berl) (2005) 1.63
Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition. J Immunol (2006) 1.61
TWEAK attenuates the transition from innate to adaptive immunity. Cell (2005) 1.59
Oxygen reduction on well-defined core-shell nanocatalysts: particle size, facet, and Pt shell thickness effects. J Am Chem Soc (2009) 1.55
Prevention of child behavior problems through universal implementation of a group behavioral family intervention. Prev Sci (2005) 1.54
Malignant transformation of testicular teratoma: a chemoresistant phenotype. Urol Oncol (2008) 1.54
An integrated high-throughput data acquisition system for biological solution X-ray scattering studies. J Synchrotron Radiat (2012) 1.52
Antecedents of hospital admission for deliberate self-harm from a 14-year follow-up study using data-linkage. BMC Psychiatry (2010) 1.50
Estimating the risk of Amazonian forest dieback. New Phytol (2010) 1.50
Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-type gastric cancer in a Chinese population. Int J Cancer (2010) 1.49
Viable germ cell tumor at postchemotherapy retroperitoneal lymph node dissection: can we predict patients at risk of disease progression? Cancer (2007) 1.49
Surgical management of growing teratoma syndrome: the M. D. Anderson cancer center experience. J Urol (2007) 1.49
Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer. Clin Cancer Res (2009) 1.48
miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. Med Oncol (2011) 1.48
Heliox versus oxygen for nebulized aerosol therapy in children with lower airway obstruction. Pediatr Crit Care Med (2002) 1.46
miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. Carcinogenesis (2012) 1.45
Prednisolone and cefapirin act synergistically in resolving experimental Escherichia coli mastitis. J Dairy Sci (2013) 1.45
A simple automated stimulator of mechanically induced arrhythmias in the isolated rat heart. Exp Physiol (2009) 1.44
Modified suprapubic prostatectomy without irrigation is safe. Urology (2009) 1.43
Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy. PLoS Pathog (2013) 1.43
Three-dimensional reconstruction of the uterine vascular supply through vascular casting and thin slice computed tomography scanning. Minim Invasive Ther Allied Technol (2009) 1.42
Effect of indacaterol on exercise endurance and lung hyperinflation in COPD. Respir Med (2011) 1.41
Plasma clozapine and haloperidol concentrations in adolescents with childhood-onset schizophrenia: association with response. J Clin Psychiatry (1994) 1.40
New understanding of hardening mechanism of TiN/SiNx-based nanocomposite films. Nanoscale Res Lett (2013) 1.39
Smoke signals. Recognition and treatment of combustion-induced cyanide toxicity. JEMS (2009) 1.39
Long-term outcomes of 1,263 patients with mycosis fungoides and Sézary syndrome from 1982 to 2009. Clin Cancer Res (2012) 1.39
miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. Cancer Chemother Pharmacol (2011) 1.39
A modified toxicity probability interval method for dose-finding trials. Clin Trials (2010) 1.37
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. Cochrane Database Syst Rev (2009) 1.37
C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice. Proc Natl Acad Sci U S A (2011) 1.36
Resveratrol protects human lens epithelial cells against H2O2-induced oxidative stress by increasing catalase, SOD-1, and HO-1 expression. Mol Vis (2010) 1.35
TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer. Mol Cell (2012) 1.34
Core-protected platinum monolayer shell high-stability electrocatalysts for fuel-cell cathodes. Angew Chem Int Ed Engl (2010) 1.34
Mortality in individuals who have had psychiatric treatment: population-based study in Nova Scotia. Br J Psychiatry (2005) 1.34
In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus. J Clin Invest (2003) 1.33
Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid plexus tumors. J Neurooncol (2007) 1.33
Chitosan modification and pharmaceutical/biomedical applications. Mar Drugs (2010) 1.33
Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma. Cancer (2012) 1.32
A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia. Proc Natl Acad Sci U S A (2009) 1.32
An investigation of the self-assembly of neutral, interlaced, triple-stranded molecular braids. Chemistry (2006) 1.31
Serum sTNF-R1, IL-6, and the development of fatigue in patients with gastrointestinal cancer undergoing chemoradiation therapy. Brain Behav Immun (2012) 1.31
Advance in chitosan hydrolysis by non-specific cellulases. Bioresour Technol (2008) 1.31
Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design. Pulm Pharmacol Ther (2010) 1.30
APRIL-deficient mice have normal immune system development. Mol Cell Biol (2004) 1.29
Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats. Lab Invest (2010) 1.29
Sorafenib inhibits transforming growth factor β1-mediated epithelial-mesenchymal transition and apoptosis in mouse hepatocytes. Hepatology (2011) 1.28