Published in Intensive Care Med on April 20, 2004
The role of empirical research in bioethics. Am J Bioeth (2009) 12.06
Expanding the paradigm of the physician's role in surrogate decision-making: an empirically derived framework. Crit Care Med (2010) 3.54
Practical guidance for evidence-based ICU family conferences. Chest (2008) 2.68
Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: a report from the IPAL-ICU Project (Improving Palliative Care in the ICU). Crit Care Med (2010) 2.49
End-of-life care policy: An integrated care plan for the dying: A Joint Position Statement of the Indian Society of Critical Care Medicine (ISCCM) and the Indian Association of Palliative Care (IAPC). Indian J Crit Care Med (2014) 2.33
In their own words: patients and families define high-quality palliative care in the intensive care unit. Crit Care Med (2010) 2.08
Comparing clinician ratings of the quality of palliative care in the intensive care unit. Crit Care Med (2011) 1.81
I don't want to be the one saying 'we should just let him die': intrapersonal tensions experienced by surrogate decision makers in the ICU. J Gen Intern Med (2012) 1.76
Development and pilot testing of a decision aid for surrogates of patients with prolonged mechanical ventilation. Crit Care Med (2012) 1.76
Trends in end-of-life ICU use among older adults with advanced lung cancer. Chest (2007) 1.76
Improving comfort and communication in the ICU: a practical new tool for palliative care performance measurement and feedback. Qual Saf Health Care (2006) 1.62
Withholding and withdrawing life support in critical care settings: ethical issues concerning consent. J Med Ethics (2007) 1.54
Neglect of quality-of-life considerations in intensive care unit family meetings for long-stay intensive care unit patients. Crit Care Med (2012) 1.43
Evidence and consensus-based German guidelines for the management of analgesia, sedation and delirium in intensive care--short version. Ger Med Sci (2010) 1.30
Family member satisfaction with end-of-life decision making in the ICU. Chest (2008) 1.26
Guidelines for end-of-life and palliative care in Indian intensive care units' ISCCM consensus Ethical Position Statement. Indian J Crit Care Med (2012) 1.19
Integrating Palliative Care in the ICU: The Nurse in a Leading Role. J Hosp Palliat Nurs (2011) 1.15
The changing role of palliative care in the ICU. Crit Care Med (2014) 1.10
Bioethics in practice: a quarterly column about medical ethics - the value of bioethics consults. Ochsner J (2012) 1.08
The distinct clinical profile of chronically critically ill patients: a cohort study. Crit Care (2006) 1.08
Association between physicians' beliefs and the option of comfort care for critically ill patients. Intensive Care Med (2012) 1.07
Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med (2014) 1.05
Withdrawing may be preferable to withholding. Crit Care (2005) 1.02
Family members' experiences of "wait and see" as a communication strategy in end-of-life decisions. Intensive Care Med (2011) 1.02
Respiratory support withdrawal in intensive care units: families, physicians and nurses views on two hypothetical clinical scenarios. Crit Care (2010) 1.00
Shared decision-making in pediatric allogeneic blood and marrow transplantation: what if there is no decision to make? Oncologist (2012) 1.00
Shared Decision Making in ICUs: An American College of Critical Care Medicine and American Thoracic Society Policy Statement. Crit Care Med (2016) 1.00
Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version. Ger Med Sci (2015) 0.94
A prospective determination of the incidence of perceived inappropriate care in critically ill patients. Can Respir J (2013) 0.93
Mandatory ethics consultation policy. Mayo Clin Proc (2009) 0.91
End-of-life decisions in Greek intensive care units: a multicenter cohort study. Crit Care (2010) 0.87
End-of-Life Practices in the Intensive Care Unit: The Importance of Geography, Religion, Religious Affiliation, and Culture. Rambam Maimonides Med J (2014) 0.87
The influence of the media on COPD patients' knowledge regarding cardiopulmonary resuscitation. Int J Chron Obstruct Pulmon Dis (2008) 0.84
Health-care system distrust in the intensive care unit. J Crit Care (2011) 0.83
Intensive care unit prognostic factors in critically ill patients with advanced solid tumors: a 3-year retrospective study. BMC Cancer (2016) 0.82
Involvement of ICU families in decisions: fine-tuning the partnership. Ann Intensive Care (2014) 0.82
Moral obligations of nurses and physicians in neonatal end-of-life care. Nurs Ethics (2010) 0.81
Catecholamine dosing and survival in adult intensive care unit patients. World J Surg (2013) 0.79
Palliative critical care in the intensive care unit: A 2011 perspective. Int J Crit Illn Inj Sci (2011) 0.79
Insights into temporal patterns of hospital patient safety from routinely collected electronic data. Health Inf Sci Syst (2015) 0.79
Experiences in recruiting volunteers through community based initiatives in phase-1 vaccine trials in India. Hum Vaccin Immunother (2013) 0.78
[Limiting or withholding treatment: the principal of "primum nihil nocere"]. Wien Klin Wochenschr (2006) 0.78
Consultation of parents in actual end-of-life decision-making in neonates and infants. Eur J Pediatr (2006) 0.78
Constitutional and Legal Protection for Life Support Limitation in India. Indian J Palliat Care (2015) 0.78
Shared Decision-Making in Intensive Care Units. Executive Summary of the American College of Critical Care Medicine and American Thoracic Society Policy Statement. Am J Respir Crit Care Med (2016) 0.77
Withholding and withdrawal of life-sustaining treatments in low-middle-income versus high-income Asian countries and regions. Intensive Care Med (2016) 0.75
Ethics review: position papers and policies--are they really helpful to front-line ICU teams? Crit Care (2006) 0.75
Simplified Acute Physiology Score II as Predictor of Mortality in Intensive Care Units: A Decision Curve Analysis. PLoS One (2016) 0.75
Availability of Advance Care Planning Documentation for Older Emergency Department Patients: A Cross-Sectional Study. J Palliat Med (2016) 0.75
Respiratory support withdrawal in intensive care units: international differences stressed and straightened! Crit Care (2011) 0.75
Palliative care in the pediatric ICU: challenges and opportunities for family-centered practice. J Soc Work End Life Palliat Care (2012) 0.75
Limiting intensive care therapy in dying critically Ill patients: Experience from a tertiary care center in United Arab Emirates. Int J Crit Illn Inj Sci (2013) 0.75
Variability in protocols on donation after circulatory death in Europe. Crit Care (2013) 0.75
Long-term outcomes after in-hospital CPR in older adults with chronic illness. Chest (2014) 0.75
Framework for decision-making and management of end-of-life decisions in Intensive Care Units: A modified protocol. Indian J Crit Care Med (2015) 0.75
Does regional variation impact decision-making in the management and palliation of pancreatic head adenocarcinoma? Results from an international survey. Can J Surg (2014) 0.75
It is settled: the 'is' can (and should) inform the 'ought'! Am J Bioeth (2009) 0.75
Developing a Research Agenda for Integrating Palliative Care into Critical Care and Pulmonary Practice To Improve Patient and Family Outcomes. J Palliat Med (2017) 0.75
Advance Directive in End of Life Decision-Making among the Yoruba of South-Western Nigeria. BEOnline (2016) 0.75
[Finding the right words for medical decisions at life's end]. Wien Klin Wochenschr (2008) 0.75
The possible impact of the German DRGs reimbursement system on end-of-life decision making in a surgical intensive care unit. Wien Klin Wochenschr (2015) 0.75
Awareness and use of recommendations for withholding and withdrawing therapy in Austrian intensive care units. Wien Med Wochenschr (2010) 0.75
Factors associated with life-sustaining treatment restriction in a general intensive care unit. PLoS One (2017) 0.75
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med (2008) 19.93
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37
Hydrocortisone therapy for patients with septic shock. N Engl J Med (2008) 15.85
Sepsis in European intensive care units: results of the SOAP study. Crit Care Med (2006) 11.78
International study of the prevalence and outcomes of infection in intensive care units. JAMA (2009) 11.57
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
Anemia and blood transfusion in critically ill patients. JAMA (2002) 7.83
Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med (2014) 7.07
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69
Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA (2009) 6.55
Regions of strong coupling between soil moisture and precipitation. Science (2004) 5.96
Perioperative fluid therapy with tetrastarch and gelatin in cardiac surgery--a prospective sequential analysis*. Crit Care Med (2013) 5.88
The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA (2003) 4.54
Prognostic value of extravascular lung water in critically ill patients. Chest (2002) 4.46
A positive fluid balance is associated with a worse outcome in patients with acute renal failure. Crit Care (2008) 4.31
High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest (2005) 3.58
A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality. Intensive Care Med (2014) 3.56
Lactate measurements in sepsis-induced tissue hypoperfusion: results from the Surviving Sepsis Campaign database. Crit Care Med (2015) 3.55
The effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials. Crit Care Med (2013) 3.43
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med (2014) 3.37
Prophylactic heparin in patients with severe sepsis treated with drotrecogin alfa (activated). Am J Respir Crit Care Med (2007) 3.34
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock. Intensive Care Med (2009) 3.30
Identification and characterisation of the high-risk surgical population in the United Kingdom. Crit Care (2006) 3.30
Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients: a randomized controlled trial. JAMA (2010) 3.20
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Current practice in nutritional support and its association with mortality in septic patients--results from a national, prospective, multicenter study. Crit Care Med (2008) 3.12
Usefulness of transcranial echography in patients with decompressive craniectomy: a comparison with computed tomography scan. Crit Care Med (2012) 3.10
Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med (2007) 2.97
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Biomarkers of sepsis. Crit Care Med (2009) 2.88
Stopping smoking shortly before surgery and postoperative complications: a systematic review and meta-analysis. Arch Intern Med (2011) 2.80
Non-invasive ventilation in acute respiratory failure. Lancet (2009) 2.77
Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med (2005) 2.73
In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. Intensive Care Med (2006) 2.72
Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med (2003) 2.64
A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis. Intensive Care Med (2009) 2.60
Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study. Crit Care Med (2006) 2.47
Evaluation of patient skin breakdown and comfort with a new face mask for non-invasive ventilation: a multi-center study. Intensive Care Med (2002) 2.46
Practice and perception--a nationwide survey of therapy habits in sepsis. Crit Care Med (2008) 2.43
High-dose vasopressin is not superior to norepinephrine in septic shock. Crit Care Med (2003) 2.43
Adequacy of antimicrobial treatment and outcome of Staphylococcus aureus bacteremia in 9 Western European countries. Clin Infect Dis (2009) 2.39
Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: a prospective sequential comparison. Crit Care Med (2011) 2.30
The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med (2011) 2.28
Obesity is associated with increased morbidity but not mortality in critically ill patients. Intensive Care Med (2008) 2.27
Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence Study. Nephrol Dial Transplant (2007) 2.25
The efficacy and safety of colloid resuscitation in the critically ill. Anesth Analg (2010) 2.23
Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure. Crit Care Med (2005) 2.12
Attributable costs of patients with candidemia and potential implications of polymerase chain reaction-based pathogen detection on antifungal therapy in patients with sepsis. J Crit Care (2012) 2.11
Antiplatelet drugs and outcome in mixed admissions to an intensive care unit. Crit Care Med (2010) 2.08
Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome. Am J Respir Crit Care Med (2014) 2.05
Euthanasia, therapeutic obstinacy or something else? An Italian case. Intensive Care Med (2005) 2.03
Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000. Crit Care Med (2003) 2.01
An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study. Intensive Care Med (2006) 2.00
A systematic review of third-generation hydroxyethyl starch (HES 130/0.4) in resuscitation: safety not adequately addressed. Anesth Analg (2011) 2.00
Noninvasive versus invasive ventilation for acute respiratory failure in patients with hematologic malignancies: a 5-year multicenter observational survey. Crit Care Med (2011) 1.96
Fluid replacement with hydroxyethyl starch in critical care--a reassessment. Dtsch Arztebl Int (2013) 1.87
Multiple mechanisms of Amazonian forest biomass losses in three dynamic global vegetation models under climate change. New Phytol (2010) 1.85
Fluctuations in serum sodium level are associated with an increased risk of death in surgical ICU patients. Crit Care Med (2013) 1.85
Prospective assessment of hepatic function and mechanisms of dysfunction in the critically ill. Shock (2009) 1.82
Who should manage the dying patient?: Rescue, shame, and the surgical ICU dilemma. J Am Coll Surg (2002) 1.81
Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial. Crit Care Med (2004) 1.80
A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Crit Care Resusc (2013) 1.77
The late phase of sepsis is characterized by an increased microbiological burden and death rate. Crit Care (2011) 1.77
Diagnosis of ventilator-associated pneumonia: a systematic review of the literature. Crit Care (2008) 1.76
Lipopolysaccharide binding protein in a surgical intensive care unit: a marker of sepsis? Crit Care Med (2008) 1.73
Systemic inflammatory response and progression to severe sepsis in critically ill infected patients. Am J Respir Crit Care Med (2004) 1.72
Effects of fluid resuscitation with synthetic colloids or crystalloids alone on shock reversal, fluid balance, and patient outcomes in patients with severe sepsis: a prospective sequential analysis. Crit Care Med (2012) 1.71
Influence of hydroxyethyl starch (HES) 130/0.4 on hemostasis as measured by viscoelastic device analysis: a systematic review. Intensive Care Med (2011) 1.66
Hospital Incidence and Mortality Rates of Sepsis. Dtsch Arztebl Int (2016) 1.65
Noninvasive ventilation after early extubation in patients recovering from hypoxemic acute respiratory failure: a single-centre feasibility study. Intensive Care Med (2012) 1.63
Risk factors for acute kidney injury in critically ill patients receiving high intravenous doses of colistin methanesulfonate and/or other nephrotoxic antibiotics: a retrospective cohort study. Crit Care (2013) 1.60
Diagnostic accuracy of passive leg raising for prediction of fluid responsiveness in adults: systematic review and meta-analysis of clinical studies. Intensive Care Med (2010) 1.58
Noninvasive positive-pressure ventilation with different interfaces in patients with respiratory failure after abdominal surgery: a matched-control study. Respir Care (2007) 1.57
A multicenter, randomized trial of noninvasive ventilation with helium-oxygen mixture in exacerbations of chronic obstructive lung disease. Crit Care Med (2010) 1.56
Noninvasive positive pressure ventilation in critical and palliative care settings: understanding the goals of therapy. Crit Care Med (2007) 1.55
Ventilator-associated pneumonia: current status and future recommendations. J Clin Monit Comput (2010) 1.54
A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality. Intensive Care Med (2015) 1.54
The importance of religious affiliation and culture on end-of-life decisions in European intensive care units. Intensive Care Med (2007) 1.52
Non-invasive ventilation delivered by conventional interfaces and helmet in the emergency department. Eur J Emerg Med (2003) 1.51
Online vs live methods for teaching difficult airway management to anesthesiology residents. Intensive Care Med (2005) 1.51
Estimating the risk of Amazonian forest dieback. New Phytol (2010) 1.50
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Med (2012) 1.47
Heliox versus oxygen for nebulized aerosol therapy in children with lower airway obstruction. Pediatr Crit Care Med (2002) 1.46
Levels of vancomycin in the cerebral interstitial fluid after severe head injury. Intensive Care Med (2006) 1.46
Prednisolone and cefapirin act synergistically in resolving experimental Escherichia coli mastitis. J Dairy Sci (2013) 1.45
Important issues in the design and reporting of clinical trials in severe sepsis and acute lung injury. J Crit Care (2008) 1.43
The world's major religions' points of view on end-of-life decisions in the intensive care unit. Intensive Care Med (2007) 1.43
In-hospital cardiac arrest: survival depends mainly on the effectiveness of the emergency response. Resuscitation (2004) 1.41
Endotoxin and the hypothalamo-pituitary-adrenal (HPA) axis. J Endotoxin Res (2003) 1.41
Perioperative management of antiplatelet therapy in patients with coronary stents undergoing cardiac and non-cardiac surgery: a consensus document from Italian cardiological, surgical and anaesthesiological societies. EuroIntervention (2014) 1.41
Venous oximetry. Curr Opin Crit Care (2006) 1.41