Published in Blood Rev on December 15, 2011
Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation. Autophagy (2013) 0.98
The expression of the glucocorticoid receptor in human erythroblasts is uniquely regulated by KIT ligand: implications for stress erythropoiesis. Stem Cells Dev (2012) 0.83
Phylogenetic and Ontogenetic View of Erythroblastic Islands. Biomed Res Int (2015) 0.79
Manufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concerns. Front Cell Dev Biol (2014) 0.78
The potential role of cell penetrating peptides in the intracellular delivery of proteins for therapy of erythroid related disorders. Pharmaceuticals (Basel) (2013) 0.76
Malaria modeling: In vitro stem cells vs in vivo models. World J Stem Cells (2016) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
The serial cultivation of human diploid cell strains. Exp Cell Res (1961) 25.11
Hematopoiesis: an evolving paradigm for stem cell biology. Cell (2008) 11.95
Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis. JAMA (2008) 8.60
Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell (1986) 5.43
Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell (1990) 5.06
Retracted Spontaneous human adult stem cell transformation. Cancer Res (2005) 4.95
Induction of colonies of hemoglobin-synthesizing cells by erythropoietin in vitro. Proc Natl Acad Sci U S A (1971) 4.49
Isolation and characterization of genomic and cDNA clones of human erythropoietin. Nature (1985) 4.23
Identification of a ligand for the c-kit proto-oncogene. Cell (1990) 4.04
Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells. Nat Biotechnol (2004) 3.76
Sarcoma derived from cultured mesenchymal stem cells. Stem Cells (2006) 3.40
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms. Cancer Res (2007) 3.19
The beta-thalassemias. N Engl J Med (1999) 3.19
Blood collection and transfusion in the United States in 2001. Transfusion (2007) 3.12
Differentiation in erythroleukemic cells and their somatic hybrids. Proc Natl Acad Sci U S A (1975) 3.05
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood (2010) 3.03
Proof of principle for transfusion of in vitro-generated red blood cells. Blood (2011) 3.01
Erythroblastic islands: niches for erythropoiesis. Blood (2008) 2.93
Primary structure and functional expression of rat and human stem cell factor DNAs. Cell (1990) 2.88
Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B. Genes Dev (2008) 2.68
Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood (2003) 2.42
Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype. Blood (2008) 2.23
Current issues relating to the transfusion of stored red blood cells. Vox Sang (2009) 2.18
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells. Blood (2009) 2.12
Vesicle trafficking plays a novel role in erythroblast enucleation. Blood (2010) 2.07
Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo. Nat Biotechnol (2002) 2.03
Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Exp Hematol (2007) 1.98
The glucocorticoid receptor is required for stress erythropoiesis. Genes Dev (1999) 1.92
Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus. Blood (2010) 1.91
Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc Natl Acad Sci U S A (2009) 1.88
The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro. Blood (1999) 1.87
The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids (2005) 1.83
The future of ageing. Nature (2000) 1.79
Proliferation and maturation of human erythroid progenitors in liquid culture. Blood (1989) 1.78
Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors. Blood (2004) 1.70
In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients. Blood Cells Mol Dis (2002) 1.70
Dynamics of GATA transcription factor expression during erythroid differentiation. Blood (1993) 1.69
The human glucocorticoid receptor: molecular basis of biologic function. Steroids (2009) 1.69
Transfusion errors in New York State: an analysis of 10 years' experience. Transfusion (2000) 1.62
Large-scale production of embryonic red blood cells from human embryonic stem cells. Exp Hematol (2006) 1.61
Global gene expression analysis of human erythroid progenitors. Blood (2011) 1.59
Development of antibodies to fetal calf serum with arthus-like reactions in human immunodeficiency virus-infected patients given syngeneic lymphocyte infusions. Blood (1997) 1.58
Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells. Nat Biotechnol (2006) 1.58
The hazards of blood transfusion in historical perspective. Blood (2008) 1.54
Polycythemia as the first manifestation of Cushing's disease. J Endocrinol Invest (2006) 1.54
The role of VEGF in normal and neoplastic hematopoiesis. J Mol Med (Berl) (2002) 1.54
Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans. Blood (2007) 1.52
Fetal and adult hemoglobin production during adult erythropoiesis: coordinate expression correlates with cell proliferation. Blood (2002) 1.48
Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proc Natl Acad Sci U S A (1992) 1.45
Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro. Blood (1998) 1.43
A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger. Exp Hematol (2008) 1.42
Caspase-3 has a nonapoptotic function in erythroid maturation. Blood (2004) 1.41
Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiol Genomics (2006) 1.41
The majority of the in vitro erythroid expansion potential resides in CD34(-) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples. Haematologica (2010) 1.39
Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry. Blood (1991) 1.36
Histone deacetylase inhibitor valproic acid enhances the cytokine-induced expansion of human hematopoietic stem cells. Cancer Res (2005) 1.35
The aging population poses a global challenge for blood services. Transfusion (2009) 1.34
The expression of human blood group antigens during erythropoiesis in a cell culture system. Blood (1999) 1.33
Potentiation of erythropoiesis in vitro by dexamethasone. J Clin Invest (1976) 1.29
Analysis of maternal and neonatal factors that influence the nucleated and CD34+ cell yield for cord blood banking. Transfusion (2004) 1.27
Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages. Int J Hematol (2008) 1.27
Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells. Blood (1996) 1.26
Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. Haematologica (2010) 1.25
Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR. Oncogene (2006) 1.22
Erythroid cells in vitro: from developmental biology to blood transfusion products. Curr Opin Hematol (2009) 1.20
Globin phenotype of erythroid cells derived from human induced pluripotent stem cells. Blood (2010) 1.19
Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation. Blood (2007) 1.17
Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. Blood (2006) 1.17
Diverse hematopoietic potentials of five human embryonic stem cell lines. Exp Cell Res (2008) 1.17
Banking of pluripotent adult stem cells as an unlimited source for red blood cell production: potential applications for alloimmunized patients and rare blood challenges. Transfus Med Rev (2011) 1.17
Epigenetic control of the variable expression of a Plasmodium falciparum receptor protein for erythrocyte invasion. Proc Natl Acad Sci U S A (2010) 1.17
Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming. Blood (2009) 1.15
Establishment of mouse embryonic stem cell-derived erythroid progenitor cell lines able to produce functional red blood cells. PLoS One (2008) 1.15
Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor. Mol Cell Biol (1995) 1.15
Estrogen-induced apoptosis by inhibition of the erythroid transcription factor GATA-1. Mol Cell Biol (1996) 1.13
Corticosteroid receptor genetic polymorphisms and stress responsivity. Endocrine (2005) 1.12
Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. Exp Hematol (2006) 1.12
Circulating erythropoietic precursors assessed in culture: characterization in normal men and patients with hemoglobinopathies. Blood (1977) 1.11
Stage-specific susceptibility of human erythroblasts to Plasmodium falciparum malaria infection. Blood (2009) 1.10
Inhibition of erythropoiesis by estrogens. Endocrinology (1961) 1.09
Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells. J Clin Invest (1994) 1.08
Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions. Crit Care (1999) 1.08
Gene expression in proliferating human erythroid cells. Genomics (1999) 1.08
Humanized culture medium for clinical expansion of human erythroblasts. Cell Transplant (2010) 1.07
Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway. Blood (2011) 1.03
Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor. Blood (1992) 1.03
Two-phase liquid culture system models normal human adult erythropoiesis at the molecular level. Eur J Haematol (2000) 1.02
Inhibition of mouse GATA-1 function by the glucocorticoid receptor: possible mechanism of steroid inhibition of erythroleukemia cell differentiation. Mol Endocrinol (1993) 0.99
The two-step liquid culture: a novel procedure for studying maturation of human normal and pathological erythroid precursors. Stem Cells (1993) 0.97
Stem cells--a source of adult red blood cells for transfusion purposes: present and future. Crit Care Clin (2009) 0.96
Human stem-progenitor cells from neonatal cord blood have greater hematopoietic expansion capacity than those from mobilized adult blood. Exp Hematol (2002) 0.95
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients. Blood (2011) 0.92
c-kit ligand reactivates fetal hemoglobin synthesis in serum-free culture of stringently purified normal adult burst-forming unit-erythroid. Blood (1993) 0.92
The predictive value of white cell or CD34+ cell count in the peripheral blood for timing apheresis and maximizing yield. Transfusion (1999) 0.92
Use of sentinel sites for daily monitoring of the US blood supply. Transfusion (2003) 1.97
Sickle cell trait and the risk of venous thromboembolism among blacks. Blood (2007) 1.95
Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med (2011) 1.75
Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. Cancer Res (2005) 1.31
Erythroid cells in vitro: from developmental biology to blood transfusion products. Curr Opin Hematol (2009) 1.20
Crosstalk between EGFR and extranuclear steroid receptors. Ann N Y Acad Sci (2006) 1.18
Humanized culture medium for clinical expansion of human erythroblasts. Cell Transplant (2010) 1.07
The potential of stem cells as an in vitro source of red blood cells for transfusion. Cell Stem Cell (2012) 1.06
Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells. Mol Cell Biol (2004) 1.02
Hormonal contraception, sickle cell trait, and risk for venous thromboembolism among African American women. Am J Obstet Gynecol (2009) 0.96
Concise review: stem cell-derived erythrocytes as upcoming players in blood transfusion. Stem Cells (2012) 0.94
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients. Blood (2011) 0.92
Rapid signalling pathway activation by androgens in epithelial and stromal cells. Steroids (2004) 0.87
The prevalence of the prothrombin gene variant C20209T in African-Americans and Caucasians and lack of association with venous thromboembolism. Thromb Res (2006) 0.86
Under HEMA conditions, self-replication of human erythroblasts is limited by autophagic death. Blood Cells Mol Dis (2011) 0.85
The expression of the glucocorticoid receptor in human erythroblasts is uniquely regulated by KIT ligand: implications for stress erythropoiesis. Stem Cells Dev (2012) 0.83
Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ mice. Stem Cells Int (2011) 0.82
Phenotypic definition of the progenitor cells with erythroid differentiation potential present in human adult blood. Stem Cells Int (2011) 0.82
Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition. Blood (2013) 0.82
Hypoxia-induced down-modulation of PKCepsilon promotes trail-mediated apoptosis of tumor cells. Int J Oncol (2010) 0.79
Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera. Am J Hematol (2013) 0.79
Increased frequency of the glucocorticoid receptor A3669G (rs6198) polymorphism in patients with Diamond-Blackfan anemia. Blood (2011) 0.79
Long-term storage does not alter functionality of in vitro generated human erythroblasts: implications for ex vivo generated erythroid transfusion products. Transfusion (2009) 0.78
Protein kinase Cε regulates proliferation and cell sensitivity to TGF-1β of CD4+ T lymphocytes: implications for Hashimoto thyroiditis. J Immunol (2011) 0.78
Laboratory diagnostics of inherited platelet disorders. Clin Chem Lab Med (2014) 0.76
Mononuclear cells from a rare blood donor, after freezing under good manufacturing practice conditions, generate red blood cells that recapitulate the rare blood phenotype. Transfusion (2013) 0.75
Implication of MAPK1/MAPK3 signalling pathway in t(8;9)(p22;24)/PCM1-JAK2 myelodysplastic/myeloproliferative neoplasms. Br J Haematol (2013) 0.75