Published in J Cell Physiol on April 01, 2005
Reactive oxygen species in inflammation and tissue injury. Antioxid Redox Signal (2013) 2.59
Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy. Antioxid Redox Signal (2012) 2.05
Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. J Biol Chem (2007) 1.73
The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. J Immunol (2008) 1.08
Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice. J Pharmacol Exp Ther (2008) 0.92
Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cells. Br J Pharmacol (2012) 0.88
REACTIVE OXYGEN SPECIES AND COLORECTAL CANCER. Curr Colorectal Cancer Rep (2013) 0.87
Antioxidant c-FLIP inhibits Fas ligand-induced NF-kappaB activation in a phosphatidylinositol 3-kinase/Akt-dependent manner. J Immunol (2011) 0.87
Indirect action of tumor necrosis factor-alpha in liver injury during the CD8+ T cell response to an adeno-associated virus vector in mice. Hepatology (2009) 0.84
Organic silicon protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide effects. BMC Complement Altern Med (2014) 0.82
Oxidative stress and antioxidant activity in hypothermia and rewarming: can RONS modulate the beneficial effects of therapeutic hypothermia? Oxid Med Cell Longev (2013) 0.78
Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. Biomol Ther (Seoul) (2016) 0.75
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab (2007) 4.75
Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets. PLoS Med (2006) 3.71
Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60. Virology (2003) 2.61
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer Res (2007) 2.54
Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells (2006) 2.23
Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17
Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer. Clin Cancer Res (2011) 2.08
Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes. Part Fibre Toxicol (2011) 2.08
Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem (2004) 2.07
Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes. Part Fibre Toxicol (2010) 2.05
Pathway analysis using random forests classification and regression. Bioinformatics (2006) 2.01
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity (2012) 2.01
Appalachian mountaintop mining particulate matter induces neoplastic transformation of human bronchial epithelial cells and promotes tumor formation. Environ Sci Technol (2014) 2.00
Mechanisms of nanoparticle-induced oxidative stress and toxicity. Biomed Res Int (2013) 1.97
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J Immunol (2009) 1.94
Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun (2003) 1.91
MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression. PLoS One (2011) 1.90
PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages. J Biol Chem (2004) 1.89
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal (2006) 1.87
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol (2004) 1.85
AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway. Cancer Res (2007) 1.85
Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression. J Biol Chem (2006) 1.83
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Commun (2003) 1.82
Inflammation and lung cancer: roles of reactive oxygen/nitrogen species. J Toxicol Environ Health B Crit Rev (2008) 1.79
Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. J Biol Chem (2006) 1.78
MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res (2011) 1.77
Evaluation of replication and pathogenicity of avian influenza a H7 subtype viruses in a mouse model. J Virol (2007) 1.76
Aspirin plus clopidogrel therapy increases early venous graft patency after coronary artery bypass surgery a single-center, randomized, controlled trial. J Am Coll Cardiol (2010) 1.73
Molecular mechanisms of arsenic carcinogenesis. Mol Cell Biochem (2004) 1.66
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation. A novel antiapoptotic mechanism that suppresses apoptosis. J Biol Chem (2006) 1.61
Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation. Am J Physiol Cell Physiol (2010) 1.60
Metal-induced oxidative stress and signal transduction. Free Radic Biol Med (2004) 1.59
PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis. Cell Signal (2007) 1.58
Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. FASEB J (2005) 1.56
Constructing molecular classifiers for the accurate prognosis of lung adenocarcinoma. Clin Cancer Res (2006) 1.55
Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease. J Biol Chem (2002) 1.54
Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells. Am J Physiol Cell Physiol (2012) 1.54
Cytoplasm-localized SIRT1 enhances apoptosis. J Cell Physiol (2007) 1.52
Confirmation of gene expression-based prediction of survival in non-small cell lung cancer. Clin Cancer Res (2008) 1.49
PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. Am J Physiol Cell Physiol (2003) 1.49
A live attenuated cold-adapted influenza A H7N3 virus vaccine provides protection against homologous and heterologous H7 viruses in mice and ferrets. Virology (2008) 1.48
Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer. Mol Pharmacol (2005) 1.47
ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene (2005) 1.46
Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort. PLoS One (2010) 1.46
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling. J Biol Chem (2004) 1.45
Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. Cardiovasc Diabetol (2011) 1.45
Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts. J Toxicol Environ Health A (2010) 1.45
Optimizing CAD diagnosis in China with CT angiography. J Cardiovasc Comput Tomogr (2009) 1.43
Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem (2010) 1.43
Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease. Stem Cells (2006) 1.43
A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1. J Mol Cell Biol (2012) 1.42
Analysis of pathogenesis of juvenile new-onset diabetes. J Diabetes (2011) 1.42
A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes (2007) 1.41
Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species. J Biol Chem (2002) 1.41
Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling. Part Fibre Toxicol (2009) 1.41
Predicting cancer drug response by proteomic profiling. Clin Cancer Res (2006) 1.39
A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta. J Biol Chem (2002) 1.38
Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies. Part Fibre Toxicol (2010) 1.38
Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination. Cancer Res (2006) 1.38
Protection of visual functions by human neural progenitors in a rat model of retinal disease. PLoS One (2007) 1.38
Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals. Chem Res Toxicol (2004) 1.37
Rapid response of a grassland ecosystem to an experimental manipulation of a keystone rodent and domestic livestock. Ecology (2010) 1.36
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. Toxicol Sci (2011) 1.34
Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer. Curr Cancer Drug Targets (2013) 1.33
Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1alpha expression through activation of AKT and P70S6K1 in human ovarian cancer cells. Free Radic Biol Med (2006) 1.32
Classification of gluteal muscle contracture in children and outcome of different treatments. BMC Musculoskelet Disord (2009) 1.32
Kaempferol inhibits angiogenesis and VEGF expression through both HIF dependent and independent pathways in human ovarian cancer cells. Nutr Cancer (2009) 1.31
MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1. PLoS One (2012) 1.31
Regulation of survivin by PI3K/Akt/p70S6K1 pathway. Biochem Biophys Res Commun (2010) 1.30
Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation. Cell Signal (2007) 1.29
Extrapulmonary transport of MWCNT following inhalation exposure. Part Fibre Toxicol (2013) 1.29
Characteristics of organic phosphorus fractions in different trophic sediments of lakes from the middle and lower reaches of Yangtze River region and Southwestern Plateau, China. Environ Pollut (2007) 1.29
Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis. Gastroenterology (2008) 1.27
Occupational toxicology of nickel and nickel compounds. J Environ Pathol Toxicol Oncol (2009) 1.27
Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A (2002) 1.26
Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res (2003) 1.26