Published in FASEB J on September 15, 2004
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A (2007) 5.36
Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. J Physiol (2005) 1.59
Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. J Appl Physiol (1985) (2006) 1.49
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways. Pflugers Arch (2007) 1.48
A critical review of pharmacological significance of Hydrogen Sulfide in hypertension. Indian J Pharmacol (2015) 1.42
Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice. Br J Pharmacol (2008) 1.40
Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability? J Cell Mol Med (2009) 1.38
The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo. PLoS One (2011) 1.37
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care. Crit Care (2009) 1.31
Analysis and functional prediction of reactive cysteine residues. J Biol Chem (2011) 1.29
Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research. Am J Physiol Heart Circ Physiol (2010) 1.23
VEGFR2 functions as an H2S-targeting receptor protein kinase with its novel Cys1045-Cys1024 disulfide bond serving as a specific molecular switch for hydrogen sulfide actions in vascular endothelial cells. Antioxid Redox Signal (2013) 1.16
Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol (2007) 1.13
Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide. Am J Physiol Endocrinol Metab (2011) 1.06
H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G. Br J Pharmacol (2008) 1.05
Sulfur as a signaling nutrient through hydrogen sulfide. Annu Rev Nutr (2014) 1.04
Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications. Chem Commun (Camb) (2014) 1.03
Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells. J Biol Chem (2011) 1.03
The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E(-/-) mice. Br J Pharmacol (2013) 1.02
Hydrogen sulfide triggers late-phase preconditioning in postischemic small intestine by an NO- and p38 MAPK-dependent mechanism. Am J Physiol Heart Circ Physiol (2009) 1.00
Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling. PLoS One (2011) 0.99
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2. Am J Pathol (2008) 0.99
Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling. Cell Death Dis (2014) 0.99
Altered sulfide (H(2)S) metabolism in ethylmalonic encephalopathy. Cold Spring Harb Perspect Biol (2013) 0.98
Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury. Mol Vis (2011) 0.97
Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney Int (2011) 0.96
Effective AAV-mediated gene therapy in a mouse model of ethylmalonic encephalopathy. EMBO Mol Med (2012) 0.95
The pathogenic role of cystathionine γ-lyase/hydrogen sulfide in streptozotocin-induced diabetes in mice. Am J Pathol (2011) 0.93
Redox Biology of Hydrogen Sulfide: Implications for Physiology, Pathophysiology, and Pharmacology. Redox Biol (2013) 0.91
Redox biology: computational approaches to the investigation of functional cysteine residues. Antioxid Redox Signal (2011) 0.89
Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts. Cell Biosci (2015) 0.88
H2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase. J Cell Mol Med (2008) 0.88
Highly sensitive sulphide mapping in live cells by kinetic spectral analysis of single Au-Ag core-shell nanoparticles. Nat Commun (2013) 0.86
Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats. Am J Hypertens (2011) 0.85
Interaction of hydrogen sulfide and estrogen on the proliferation of vascular smooth muscle cells. PLoS One (2012) 0.85
Hydrogen sulfide as a vasculoprotective factor. Med Gas Res (2013) 0.84
C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2. PLoS One (2013) 0.84
A practical guide to working with H2S at the interface of chemistry and biology. Chem Soc Rev (2016) 0.83
Effect of H₂S on the circadian rhythm of mouse hepatocytes. Lipids Health Dis (2012) 0.82
Annexin A1 mediates hydrogen sulfide properties in the control of inflammation. J Pharmacol Exp Ther (2014) 0.81
Cystathionine gamma-lyase-deficient smooth muscle cells exhibit redox imbalance and apoptosis under hypoxic stress conditions. Exp Clin Cardiol (2011) 0.81
The global transcriptional response of fission yeast to hydrogen sulfide. PLoS One (2011) 0.79
Role of calmodulin-calmodulin kinase II, cAMP/protein kinase A and ERK 1/2 on Aeromonas hydrophila-induced apoptosis of head kidney macrophages. PLoS Pathog (2014) 0.79
Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches. EMBO Mol Med (2015) 0.79
Characteristics and function of sulfur dioxygenase in Echiuran worm Urechis unicinctus. PLoS One (2013) 0.79
Effect of hydrogen sulfide on inflammatory cytokines in acute myocardial ischemia injury in rats. Exp Ther Med (2015) 0.79
Cytoprotective effects of albumin, nitrosated or reduced, in cultured rat pulmonary vascular cells. Am J Physiol Lung Cell Mol Physiol (2011) 0.78
Role of hydrogen sulfide in the physiology of penile erection. J Androl (2011) 0.77
Cadmium-induced hydrogen sulfide synthesis is involved in cadmium tolerance in Medicago sativa by reestablishment of reduced (homo)glutathione and reactive oxygen species homeostases. PLoS One (2014) 0.77
Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. J Toxicol (2011) 0.77
Apoptosis, metallothionein, and bioavailable metals in domestic mice (Mus musculus L.) from a human-inhabited volcanic area. Ecotoxicology (2007) 0.77
Vascular biology of hydrogen sulfide. Am J Physiol Cell Physiol (2017) 0.77
Hydrogen sulfide donor protects porcine oocytes against aging and improves the developmental potential of aged porcine oocytes. PLoS One (2015) 0.76
Transcriptional response to sulfide in the Echiuran Worm Urechis unicinctus by digital gene expression analysis. BMC Genomics (2015) 0.76
Cystathionine β-synthase-derived hydrogen sulfide regulates lipopolysaccharide-induced apoptosis of the BRL rat hepatic cell line in vitro. Exp Ther Med (2012) 0.76
Vasorelaxant Effect of a New Hydrogen Sulfide-Nitric Oxide Conjugated Donor in Isolated Rat Aortic Rings through cGMP Pathway. Oxid Med Cell Longev (2015) 0.76
H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair. Oncotarget (2016) 0.75
Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3β/β-catenin signaling pathway. Int J Mol Med (2016) 0.75
An Anticancer Role of Hydrogen Sulfide in Human Gastric Cancer Cells. Oxid Med Cell Longev (2015) 0.75
Clinical Implication of Plasma Hydrogen Sulfide Levels in Japanese Patients with Type 2 Diabetes. Intern Med (2017) 0.75
Crystallization and preliminary X-ray analysis of betaC-S lyases from two oral Streptococci. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.75
H2S biosynthesis and catabolism: new insights from molecular studies. Cell Mol Life Sci (2016) 0.75
Hydrogen Sulfide Regulates Homeostasis of Mesenchymal Stem Cells and Regulatory T Cells. J Dent Res (2016) 0.75
Cystathionine gamma-lyase expression during avian embryogenesis. J Anat (2009) 0.75
Elevated monocyte phosphorylated p38 in nearby employees after a chemical explosion. Sci Rep (2016) 0.75
Beyond a gasotransmitter: hydrogen sulfide and polysulfide in cardiovascular health and immune response. Antioxid Redox Signal (2017) 0.75
The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res (2012) 13.14
Statistics in medicine--reporting of subgroup analyses in clinical trials. N Engl J Med (2007) 12.55
H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science (2008) 7.89
H2S signals through protein S-sulfhydration. Sci Signal (2009) 4.54
Activating ESR1 mutations in hormone-resistant metastatic breast cancer. Nat Genet (2013) 3.96
Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS (2011) 3.95
Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med (2012) 3.54
Latent TGF-β structure and activation. Nature (2011) 3.42
Identification of targetable FGFR gene fusions in diverse cancers. Cancer Discov (2013) 3.13
Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe (2010) 3.08
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. Circ Res (2011) 2.94
H(2)S-induced vasorelaxation and underlying cellular and molecular mechanisms. Am J Physiol Heart Circ Physiol (2002) 2.90
Carbon monoxide: endogenous production, physiological functions, and pharmacological applications. Pharmacol Rev (2005) 2.73
Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proc Natl Acad Sci U S A (2009) 2.66
Hydrogen sulfide-induced relaxation of resistance mesenteric artery beds of rats. Am J Physiol Heart Circ Physiol (2004) 2.62
Complete transfer of perceptual learning across retinal locations enabled by double training. Curr Biol (2008) 2.62
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol (2012) 2.56
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A (2009) 2.51
Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies. J Antimicrob Chemother (2012) 2.49
Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One (2010) 2.44
SLAF-seq: an efficient method of large-scale de novo SNP discovery and genotyping using high-throughput sequencing. PLoS One (2013) 2.36
Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia. Circulation (2013) 2.34
FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood (2008) 2.31
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. Nat Genet (2013) 2.30
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3. Genome Biol (2012) 2.19
Genetic loci affecting resistance to human malaria parasites in a West African mosquito vector population. Science (2002) 2.11
The PRoteomics IDEntification (PRIDE) Converter 2 framework: an improved suite of tools to facilitate data submission to the PRIDE database and the ProteomeXchange consortium. Mol Cell Proteomics (2012) 2.10
PRIDE Inspector: a tool to visualize and validate MS proteomics data. Nat Biotechnol (2012) 2.10
Characterization of KRAS rearrangements in metastatic prostate cancer. Cancer Discov (2011) 2.02
Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med (2011) 1.96
Modulation of endogenous production of H2S in rat tissues. Can J Physiol Pharmacol (2003) 1.93
Coordinated regulation of polycomb group complexes through microRNAs in cancer. Cancer Cell (2011) 1.86
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function. Proc Natl Acad Sci U S A (2011) 1.82
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2. Antioxid Redox Signal (2013) 1.79
Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis. Clin Cancer Res (2012) 1.77
Measurement of plasma hydrogen sulfide in vivo and in vitro. Free Radic Biol Med (2011) 1.74
Systematic review and meta-analysis of the effectiveness and safety of tigecycline for treatment of infectious disease. Antimicrob Agents Chemother (2010) 1.73
The human airway epithelial basal cell transcriptome. PLoS One (2011) 1.69
H₂S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase. Circulation (2013) 1.65
PRIDE: quality control in a proteomics data repository. Database (Oxford) (2012) 1.63
Pro-apoptotic effect of endogenous H2S on human aorta smooth muscle cells. FASEB J (2006) 1.62
MicroRNA-21: a novel therapeutic target in human cancer. Cancer Biol Ther (2010) 1.62
Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells. Cancer Biol Ther (2006) 1.60
Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. J Physiol (2005) 1.59
An artificial right ventricle for failing fontan: in vitro and computational study. Ann Thorac Surg (2009) 1.58
Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proc Natl Acad Sci U S A (2014) 1.58
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 1.57
H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem (2007) 1.56
The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women. Br J Nutr (2013) 1.56
Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem (2004) 1.56
Fosfomycin: evaluation of the published evidence on the emergence of antimicrobial resistance in Gram-negative pathogens. J Antimicrob Chemother (2011) 1.55
The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression. PLoS One (2013) 1.55
Hydrogen sulfide: the third gasotransmitter in biology and medicine. Antioxid Redox Signal (2010) 1.53
Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo. Cancer Biol Ther (2008) 1.50
Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. J Appl Physiol (1985) (2006) 1.49
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production. Proc Natl Acad Sci U S A (2012) 1.49
The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J Biol Chem (2010) 1.48
Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer. Cancer Lett (2011) 1.48
From Peptidome to PRIDE: public proteomics data migration at a large scale. Proteomics (2013) 1.46
Increased expression of calcium-sensing receptors induced by ox-LDL amplifies apoptosis of cardiomyocytes during simulated ischaemia-reperfusion. Clin Exp Pharmacol Physiol (2010) 1.45
Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection. J Immunol (2008) 1.44
Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells. Biochem J (2012) 1.44
Making proteomics data accessible and reusable: current state of proteomics databases and repositories. Proteomics (2015) 1.44
Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population. Carcinogenesis (2003) 1.43
IL-17A G197A and IL-17F T7488C polymorphisms and cancer risk in Asian populations: a meta-analysis. J BUON (2014) 1.41
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? Am J Respir Cell Mol Biol (2010) 1.40
Analytical measurement of discrete hydrogen sulfide pools in biological specimens. Free Radic Biol Med (2012) 1.37
Evidence that intermittent structured treatment interruption, but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068. J Infect Dis (2006) 1.37
Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process. Nucleic Acids Res (2013) 1.36
HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission. PLoS One (2010) 1.36
Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet (2011) 1.36
The emergence of clinical resistance to tigecycline. Int J Antimicrob Agents (2012) 1.35
Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells. Mol Pharmacol (2005) 1.35
Interaction of hydrogen sulfide with ion channels. Clin Exp Pharmacol Physiol (2010) 1.34
Better control of early viral replication is associated with slower rate of elicited antiviral antibodies in the detuned enzyme immunoassay during primary HIV-1C infection. J Acquir Immune Defic Syndr (2009) 1.34
Effects of hydrogen sulfide on homocysteine-induced oxidative stress in vascular smooth muscle cells. Biochem Biophys Res Commun (2006) 1.31
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res (2010) 1.31
Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors. Am J Physiol Regul Integr Comp Physiol (2008) 1.30
Molecular mechanism for H(2)S-induced activation of K(ATP) channels. Antioxid Redox Signal (2010) 1.28
Plasma IP-10 is associated with rapid disease progression in early HIV-1 infection. Viral Immunol (2012) 1.28
Liposomal quercetin efficiently suppresses growth of solid tumors in murine models. Clin Cancer Res (2006) 1.28
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation. J Biol Chem (2008) 1.27
Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis. Circulation (2013) 1.26
Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma. Cancer Res (2007) 1.26
MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3. Cancer (2011) 1.25
The mutant selection window in rabbits infected with Staphylococcus aureus. J Infect Dis (2006) 1.25
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide. Nephrol Dial Transplant (2011) 1.24
Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. Cancer Chemother Pharmacol (2008) 1.24
Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain. J Neurochem (2010) 1.24
Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system. Proc Natl Acad Sci U S A (2004) 1.23
Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration. Biochem J (2012) 1.21
MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer. PLoS One (2012) 1.20
Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats. Lab Invest (2008) 1.20
Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer. J Exp Clin Cancer Res (2013) 1.19
The platinum-based treatments for advanced non-small cell lung cancer, is low/negative ERCC1 expression better than high/positive ERCC1 expression? A meta-analysis. Lung Cancer (2010) 1.19
The relationship between self-rated health and objective health status: a population-based study. BMC Public Health (2013) 1.18
Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis (2004) 1.18
Targeting Slit-Roundabout signaling inhibits tumor angiogenesis in chemical-induced squamous cell carcinogenesis. Cancer Sci (2008) 1.18
Hydrogen sulfide improves drought resistance in Arabidopsis thaliana. Biochem Biophys Res Commun (2011) 1.17
Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains. J Thorac Oncol (2012) 1.17