Published in Circulation on September 20, 2004
Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic. Lancet Neurol (2009) 3.27
The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest (2005) 3.22
Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect. Bone (2012) 2.24
Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ (2006) 1.79
Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats. Neurobiol Dis (2012) 1.70
Control of brain development, function, and behavior by the microbiome. Cell Host Microbe (2015) 1.48
Neuroplasticity in the context of motor rehabilitation after stroke. Nat Rev Neurol (2011) 1.45
Ischemic stroke and neurogenesis in the subventricular zone. Neuropharmacology (2008) 1.39
Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia. Proc Natl Acad Sci U S A (2007) 1.35
Neuroprotective effects of estrogens following ischemic stroke. Front Neuroendocrinol (2009) 1.28
Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction. J Mol Cell Cardiol (2008) 1.28
G-CSF rescues the memory impairment of animal models of Alzheimer's disease. J Exp Med (2007) 1.24
Hematopoietic growth factors pass through the blood-brain barrier in intact rats. Exp Neurol (2007) 1.21
Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke. J Clin Invest (2008) 1.08
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy. Hypertension (2012) 1.05
Intra-Arterial Immunoselected CD34+ Stem Cells for Acute Ischemic Stroke. Stem Cells Transl Med (2014) 1.02
Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies. Exp Transl Stroke Med (2009) 1.01
Aging of the subventricular zone neural stem cell niche. Aging Dis (2011) 1.00
Implantation of olfactory ensheathing cells promotes neuroplasticity in murine models of stroke. J Clin Invest (2008) 0.99
Hypoxia precondition promotes adipose-derived mesenchymal stem cells based repair of diabetic erectile dysfunction via augmenting angiogenesis and neuroprotection. PLoS One (2015) 0.98
An extended window of opportunity for G-CSF treatment in cerebral ischemia. BMC Biol (2006) 0.98
Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics (2011) 0.98
Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis. J Neuroinflammation (2011) 0.96
Transfusion of CXCR4-primed endothelial progenitor cells reduces cerebral ischemic damage and promotes repair in db/db diabetic mice. PLoS One (2012) 0.95
Growth factors in ischemic stroke. J Cell Mol Med (2009) 0.94
Comparison of transplantation of bone marrow stromal cells (BMSC) and stem cell mobilization by granulocyte colony stimulating factor after traumatic brain injury in rat. Iran Biomed J (2010) 0.94
A novel combinatorial therapy with pulp stem cells and granulocyte colony-stimulating factor for total pulp regeneration. Stem Cells Transl Med (2013) 0.92
Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats. Yonsei Med J (2008) 0.92
Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a comorbidity factor. J Neurosurg Sci (2014) 0.90
The potential benefit of stem cell therapy after stroke: an update. Vasc Health Risk Manag (2012) 0.89
The receptor for granulocyte-colony stimulating factor (G-CSF) is expressed in radial glia during development of the nervous system. BMC Dev Biol (2008) 0.88
Translating G-CSF as an Adjunct Therapy to Stem Cell Transplantation for Stroke. Transl Stroke Res (2015) 0.86
Stem cell therapies in preclinical models of stroke associated with aging. Front Cell Neurosci (2014) 0.85
Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy. BMC Neurosci (2009) 0.85
Granulocyte-colony stimulating factor in combination with stem cell factor confers greater neuroprotection after hypoxic-ischemic brain damage in the neonatal rats than a solitary treatment. Transl Stroke Res (2012) 0.85
Cell-based therapy for stroke. J Neural Transm (Vienna) (2010) 0.85
The magic behind stem cells. J Assist Reprod Genet (2007) 0.84
Oxygen-glucose deprivation induced glial scar-like change in astrocytes. PLoS One (2012) 0.84
Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation. J Cereb Blood Flow Metab (2010) 0.84
Stem cell therapy in stroke: a review literature. Int J Prev Med (2013) 0.83
Inflammatory Disequilibrium in Stroke. Circ Res (2016) 0.83
Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis. J Cereb Blood Flow Metab (2014) 0.83
Role of stress-inducible protein-1 in recruitment of bone marrow derived cells into the ischemic brains. EMBO Mol Med (2013) 0.83
Evaluation of neural plasticity in adult stem cells. Philos Trans R Soc Lond B Biol Sci (2008) 0.83
Hematopoietic stem cells are pluripotent and not just "hematopoietic". Blood Cells Mol Dis (2013) 0.83
G-CSF attenuates neuroinflammation and stabilizes the blood-brain barrier via the PI3K/Akt/GSK-3β signaling pathway following neonatal hypoxia-ischemia in rats. Exp Neurol (2015) 0.83
Granulocyte colony-stimulating factor treatment provides neuroprotection in surgically induced brain injured mice. Acta Neurochir Suppl (2011) 0.83
Mobilisation of hematopoietic CD34+ precursor cells in patients with acute stroke is safe--results of an open-labeled non randomized phase I/II trial. PLoS One (2011) 0.83
MRI detects brain reorganization after human umbilical tissue-derived cells (hUTC) treatment of stroke in rat. PLoS One (2012) 0.83
The effects of delayed reduction of tonic inhibition on ischemic lesion and sensorimotor function. J Cereb Blood Flow Metab (2015) 0.82
The role of stem cell factor and granulocyte-colony stimulating factor in treatment of stroke. Recent Pat CNS Drug Discov (2013) 0.82
Granulocyte colony-stimulating factor activating HIF-1alpha acts synergistically with erythropoietin to promote tissue plasticity. PLoS One (2010) 0.81
MRI of blood-brain barrier permeability in cerebral ischemia. Transl Stroke Res (2012) 0.80
Stratification substantially reduces behavioral variability in the hypoxic-ischemic stroke model. Brain Behav (2012) 0.79
Targeting nitric oxide in the subacute restorative treatment of ischemic stroke. Expert Opin Investig Drugs (2013) 0.79
Granulocyte colony stimulating factor attenuates hyperoxia-induced lung injury by down-modulating inflammatory responses in neonatal rats. Yonsei Med J (2011) 0.78
Granulocyte colony-stimulating factor (G-CSF) positive effects on muscle fiber degeneration and gait recovery after nerve lesion in MDX mice. Brain Behav (2014) 0.78
Stem cell transplantation for treating stroke: status, trends and development. Neural Regen Res (2014) 0.77
Efficacy of granulocyte-colony stimulating factor treatment in a rat model of anterior ischemic optic neuropathy. Neural Regen Res (2014) 0.75
G-CSF, rt-PA and combination therapy after experimental thromboembolic stroke. Exp Transl Stroke Med (2010) 0.75
A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics (2017) 0.75
Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury. ScientificWorldJournal (2015) 0.75
Combination of endogenous neural stem cell mobilization and lithium chloride treatment for hydrocephalus following intraventricular hemorrhage. Exp Ther Med (2016) 0.75
Current status of cell therapies in stroke. Int J Stem Cells (2009) 0.75
Granulocyte colony-stimulating factor enhances the therapeutic efficacy of bone marrow mesenchymal stem cell transplantation in rats with experimental acute pancreatitis. Oncotarget (2017) 0.75
Letter regarding article by Shyu et al, "functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells". Circulation (2005) 0.75
Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Restores the Neurobehavioral Disorders of Rats With Neonatal Hypoxic-Ischemic Encephalopathy. Cell Med (2013) 0.75
PACAP38/PAC1 signaling induces bone marrow-derived cells homing to ischemic brain. Stem Cells (2015) 0.75
Granulocyte colony stimulating factor reduces brain injury in a cardiopulmonary bypass-circulatory arrest model of ischemia in a newborn piglet. Neurochem Res (2014) 0.75
Elevated body swing test after focal cerebral ischemia in rodents: methodological considerations. BMC Neurosci (2015) 0.75
Role of IGF1R(+) MSCs in modulating neuroplasticity via CXCR4 cross-interaction. Sci Rep (2016) 0.75
Is There Additive Therapeutic Effect When GCSF Combined with Adipose-Derived Stem Cell in a Rat Model of Acute Spinal Cord Injury? J Korean Neurosurg Soc (2017) 0.75
Adjuvant immunotherapy with whole-cell lysate dendritic cells vaccine for glioblastoma multiforme: a phase II clinical trial. World Neurosurg (2011) 2.24
Endoscopic surgery for intraventricular hemorrhage (IVH) caused by thalamic hemorrhage: comparisons of endoscopic surgery and external ventricular drainage (EVD) surgery. World Neurosurg (2011) 2.21
Marjolin's ulcer: MR appearance. AJR Am J Roentgenol (2006) 2.06
Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ (2006) 1.79
Isolation and characterization of size-sieved stem cells from human bone marrow. Stem Cells (2002) 1.62
Mesenchymal stem cells. Cell Transplant (2011) 1.62
Increased risk of urinary tract calculi among patients with diabetes mellitus--a population-based cohort study. Urology (2011) 1.51
Mesenchymal stem cell insights: prospects in cardiovascular therapy. Cell Transplant (2014) 1.50
Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1. Am J Pathol (2006) 1.47
Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice. J Mol Med (Berl) (2008) 1.38
Intracerebral peripheral blood stem cell (CD34+) implantation induces neuroplasticity by enhancing beta1 integrin-mediated angiogenesis in chronic stroke rats. J Neurosci (2006) 1.34
Magnetic nanoparticle labeling of mesenchymal stem cells without transfection agent: cellular behavior and capability of detection with clinical 1.5 T magnetic resonance at the single cell level. Magn Reson Med (2007) 1.34
Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats. J Pharmacol Exp Ther (2007) 1.34
Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke (2003) 1.32
Enhancement of neuroplasticity through upregulation of beta1-integrin in human umbilical cord-derived stromal cell implanted stroke model. Neurobiol Dis (2007) 1.28
A multiplexed quantitative strategy for membrane proteomics: opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease. Mol Cell Proteomics (2008) 1.25
Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model. J Neurosci (2005) 1.21
Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells. Carcinogenesis (2009) 1.19
Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse. J Neurosci (2005) 1.17
Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts. J Clin Neurosci (2008) 1.17
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am J Respir Crit Care Med (2003) 1.16
Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis. Life Sci (2004) 1.16
The efficacy of quantitative gait analysis by the GAITRite system in evaluation of parkinsonian bradykinesia. Parkinsonism Relat Disord (2006) 1.12
Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse. Hum Mol Genet (2009) 1.12
The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo. J Neurochem (2006) 1.12
Establishing a standardized therapeutic testing protocol for spinal muscular atrophy. Neurobiol Dis (2006) 1.11
The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. Clin Cancer Res (2005) 1.10
Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy. Cell Transplant (2015) 1.09
Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke. J Clin Invest (2008) 1.08
Neuropsychological effects after chronic subthalamic stimulation and the topography of the nucleus in Parkinson's disease. Neurosurgery (2007) 1.07
Homing genes, cell therapy and stroke. Front Biosci (2006) 1.06
Exercise-induced activation of NMDA receptor promotes motor unit development and survival in a type 2 spinal muscular atrophy model mouse. J Neurosci (2008) 1.06
Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. PLoS One (2012) 1.05
Regenerative therapy for stroke. Cell Transplant (2007) 1.05
A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells. Gene Expr Patterns (2003) 1.05
EP1- and EP3-receptors mediate prostaglandin E2-induced constriction of porcine large cerebral arteries. J Cereb Blood Flow Metab (2004) 1.05
The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma cell therapy. Mol Pharmacol (2008) 1.04
Neuregulin-1 reduces ischemia-induced brain damage in rats. Neurobiol Aging (2004) 1.03
Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells. J Pharmacol Exp Ther (2007) 1.02
Efficient tracking of non-iron-labeled mesenchymal stem cells with serial MRI in chronic stroke rats. Stroke (2006) 1.02
Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models. PLoS One (2011) 1.02
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC: a highly efficient and reliable carrier-screening test. Hum Mutat (2005) 1.01
Implantation of olfactory ensheathing cells promotes neuroplasticity in murine models of stroke. J Clin Invest (2008) 0.99
Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy. Hum Mol Genet (2010) 0.99
Tophaceous gout of the lumbar spine mimicking infectious spondylodiscitis and epidural abscess: MR imaging findings. J Clin Neurosci (2005) 0.98
In vitro and in vivo studies of a novel potential anticancer agent of isochaihulactone on human lung cancer A549 cells. Biochem Pharmacol (2006) 0.98
Efficacy and safety of nanohybrids comprising silver nanoparticles and silicate clay for controlling Salmonella infection. Int J Nanomedicine (2012) 0.98
Homozygous deletion genotype of angiotensin converting enzyme confers protection against migraine in man. Acta Neurol Taiwan (2005) 0.98
Abolishing Bax-dependent apoptosis shows beneficial effects on spinal muscular atrophy model mice. Mol Ther (2006) 0.98
Restoring Bcl-x(L) levels benefits a mouse model of spinal muscular atrophy. Neurobiol Dis (2008) 0.97
Mesenchymal stem cells facilitate recovery from chemically induced liver damage and decrease liver fibrosis. Life Sci (2009) 0.97
Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin. Cancer Res (2002) 0.96
Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity. Life Sci (2003) 0.95
MicroRNAs regulation modulated self-renewal and lineage differentiation of stem cells. Cell Transplant (2009) 0.95
Adipose-derived stem cells can abrogate chemical-induced liver fibrosis and facilitate recovery of liver function. Cell Transplant (2012) 0.95
Trafficking of multipotent mesenchymal stromal cells from maternal circulation through the placenta involves vascular endothelial growth factor receptor-1 and integrins. Stem Cells (2007) 0.95
Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells. J Cell Physiol (2012) 0.95
Hyperintense putaminal rim sign is not a hallmark of multiple system atrophy at 3T. AJNR Am J Neuroradiol (2005) 0.94
Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice. Hum Mol Genet (2008) 0.94
Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in vitro and in vivo. Cancer Lett (2004) 0.93
Transplantation of endothelial progenitor cells as therapeutics for cardiovascular diseases. Cell Transplant (2009) 0.93
The role of cancer stem cells (CD133(+)) in malignant gliomas. Cell Transplant (2010) 0.93
Hyperbaric oxygen enhances the expression of prion protein and heat shock protein 70 in a mouse neuroblastoma cell line. Cell Mol Neurobiol (2004) 0.93
Orphan nuclear receptor, Nurr-77 was a possible target gene of butylidenephthalide chemotherapy on glioblastoma multiform brain tumor. J Neurochem (2008) 0.92
Targeting cancer stem cells for treatment of glioblastoma multiforme. Cell Transplant (2013) 0.92
Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth. J Agric Food Chem (2010) 0.92
Clinicopathologic correlation of up-regulated genes identified using cDNA microarray and real-time reverse transcription-PCR in human colorectal cancer. Cancer Epidemiol Biomarkers Prev (2005) 0.91
Stat5 constitutive activation rescues defects in spinal muscular atrophy. Hum Mol Genet (2007) 0.91
Polyglutamine (PolyQ) diseases: genetics to treatments. Cell Transplant (2014) 0.91
Urocortin modulates inflammatory response and neurotoxicity induced by microglial activation. J Immunol (2007) 0.90
The spinal muscular atrophy disease protein SMN is linked to the Golgi network. PLoS One (2012) 0.90
Adipose-derived stem cells: isolation, characterization, and differentiation potential. Cell Transplant (2012) 0.90
The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. Genet Test Mol Biomarkers (2009) 0.89
Stem cell-based therapy for ischemic heart disease. Cell Transplant (2012) 0.89
Endovascular repair of tracheo-innominate artery fistula. Acta Anaesthesiol Taiwan (2009) 0.88
Usefulness of brain 99mTc-TRODAT-1 SPET for the evaluation of Parkinson's disease. Eur J Nucl Med Mol Imaging (2004) 0.88
Novel nanohybrids of silver particles on clay platelets for inhibiting silver-resistant bacteria. PLoS One (2011) 0.88
Cough induced by ossification of the ligamentum flavum in the high cervical spine. Case report. J Neurosurg (2004) 0.87
G-CSF protects dopaminergic neurons from 6-OHDA-induced toxicity via the ERK pathway. Neurobiol Aging (2006) 0.87
Gene expression in early and progression phases of autosomal dominant polycystic kidney disease. BMC Res Notes (2008) 0.87