Published in J Clin Invest on January 01, 2008
Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection. Mol Neurobiol (2010) 1.51
The extended granin family: structure, function, and biomedical implications. Endocr Rev (2011) 1.43
Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia. J Neurosci (2009) 1.33
Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One (2011) 1.32
Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat. Neuroscience (2010) 1.03
Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. Stroke (2011) 1.01
Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway. J Biomed Sci (2011) 0.89
Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130. Korean J Physiol Pharmacol (2009) 0.89
Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model. Stroke Res Treat (2011) 0.85
Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia. Acta Neuropathol (2011) 0.85
Plasma and cerebrospinal proteomes from children with cerebral malaria differ from those of children with other encephalopathies. J Infect Dis (2013) 0.83
Chromogranin peptides in brain diseases. J Neural Transm (Vienna) (2011) 0.82
Granulocyte colony-stimulating factor activating HIF-1alpha acts synergistically with erythropoietin to promote tissue plasticity. PLoS One (2010) 0.81
Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis. Int J Mol Med (2014) 0.80
Proteomic Characterization of Cerebrospinal Fluid from Ataxia-Telangiectasia (A-T) Patients Using a LC/MS-Based Label-Free Protein Quantification Technology. Int J Proteomics (2011) 0.78
Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder. J Psychiatry Neurosci (2013) 0.78
The effects of lifelong blindness on murine neuroanatomy and gene expression. Front Aging Neurosci (2015) 0.77
IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice. PLoS One (2015) 0.76
Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties. PLoS One (2012) 0.76
PACAP38/PAC1 signaling induces bone marrow-derived cells homing to ischemic brain. Stem Cells (2015) 0.75
Dexmedetomidine Acts via the JAK2/STAT3 Pathway to Attenuate Isoflurane-Induced Neurocognitive Deficits in Senile Mice. PLoS One (2016) 0.75
A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics (2017) 0.75
Role of IGF1R(+) MSCs in modulating neuroplasticity via CXCR4 cross-interaction. Sci Rep (2016) 0.75
IGF1R(+) Dental Pulp Stem Cells Enhanced Neuroplasticity in Hypoxia-Ischemia Model. Mol Neurobiol (2016) 0.75
VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J (1999) 6.62
Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke (2001) 6.61
Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol (2005) 5.31
Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution. J Nucl Med (1986) 4.69
Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery. Neurology (2002) 4.45
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest (2004) 4.04
Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation (2002) 3.65
Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J Neurosci Methods (1987) 3.47
Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J Neurosci (1999) 3.36
Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol (2003) 3.09
Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood (2003) 2.93
Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke (1993) 2.85
Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience (2001) 2.84
Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells. Circulation (2004) 2.69
G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med (2005) 2.64
Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res (2003) 2.56
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations. Leukemia (2007) 2.49
A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke (1986) 2.34
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci (1993) 2.23
HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells. J Clin Invest (2001) 2.20
Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy. Nat Med (2000) 2.13
Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs. Circulation (2002) 1.85
Reversal of experimental diabetic neuropathy by VEGF gene transfer. J Clin Invest (2001) 1.73
GDNF delivery using human neural progenitor cells in a rat model of ALS. Hum Gene Ther (2005) 1.72
Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family. J Cereb Blood Flow Metab (1998) 1.71
Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice. J Cereb Blood Flow Metab (2006) 1.68
NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide. J Neurosci (2005) 1.68
Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res (1998) 1.62
Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. Blood Cells Mol Dis (2004) 1.62
Bone marrow as a source of endothelial cells and NeuN-expressing cells After stroke. Stroke (2002) 1.61
Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex. J Neurosci (1997) 1.48
Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors. FASEB J (2006) 1.33
Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke (2003) 1.32
Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke. Circulation (1996) 1.30
The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells. Blood (2004) 1.29
Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior. Exp Cell Res (2004) 1.22
STAT3 mediates bone marrow mesenchymal stem cell VEGF production. J Mol Cell Cardiol (2007) 1.14
Enteric neuroblasts require the phosphatidylinositol 3-kinase/Akt/Forkhead pathway for GDNF-stimulated survival. Mol Cell Neurosci (2005) 1.12
Rescue of lethal c-KitW/W mice by erythropoietin. Blood (2004) 1.12
Increased plasma levels of stromal-derived factor-1 (SDF-1/CXCL12) enhance human thrombopoiesis and mobilize human colony-forming cells (CFC) in NOD/SCID mice. Exp Hematol (2004) 1.11
Granulocyte colony-stimulating factor stimulates neurogenesis via vascular endothelial growth factor with STAT activation. Brain Res (2006) 1.10
Bone morphogenetic protein-6 reduces ischemia-induced brain damage in rats. Stroke (2001) 1.08
Secretogranin II: molecular properties, regulation of biosynthesis and processing to the neuropeptide secretoneurin. Prog Neurobiol (1995) 1.02
The neuropeptide secretoneurin acts as a direct angiogenic cytokine in vitro and in vivo. Circulation (2004) 0.98
Osteogenic protein-1 protects against cerebral infarction induced by MCA ligation in adult rats. Stroke (1999) 0.98
Secretoneurin, an angiogenic neuropeptide, induces postnatal vasculogenesis. Circulation (2004) 0.97
Issues and answers in stroke care. Lancet (1998) 0.94
Hypoxic neuronal necrosis: protein synthesis-independent activation of a cell death program. Proc Natl Acad Sci U S A (2003) 0.94
Differential neuronal and astrocytic expression of transforming growth factor beta isoforms in rat hippocampus following transient forebrain ischemia. Brain Res Mol Brain Res (1996) 0.94
Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience (1994) 0.93
Chromogranin peptides in Alzheimer's disease. Exp Gerontol (2004) 0.92
Synaptophysin and chromogranin A immunoreactivities of Lewy bodies in Parkinson's disease brains. Brain Res (1994) 0.91
The functional role of the JAK-STAT pathway in post-infarction remodeling. Cardiovasc Res (2003) 0.88
Chromogranins as markers of altered hippocampal circuitry in temporal lobe epilepsy. Ann Neurol (2001) 0.87
Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion. Exp Neurol (2005) 0.83
A lateralised grip strength test to evaluate unilateral nigrostriatal lesions in rats. Neurosci Lett (1998) 0.83
Synaptic loss reflected by secretoneurin-like immunoreactivity in the human hippocampus in Alzheimer's disease. Eur J Neurosci (1998) 0.83
Synaptic proteins in Alzheimer's disease. J Mol Neurosci (2002) 0.82
High resolution quantitation of microvascular plasma perfusion in non-ischemic and ischemic rat brain by laser-scanning confocal microscopy. Brain Res Brain Res Protoc (1999) 0.81
Immunohistochemical localization of secretogranin II in the rat cerebellum. Neuroscience (1989) 0.79
Inhibition of proliferation and stimulation of migration of endothelial cells by secretoneurin in vitro. Arterioscler Thromb Vasc Biol (1997) 0.79
Differential regulation of chromogranin A, chromogranin B and secretoneurin protein expression after transient forebrain ischemia in the gerbil. Acta Neuropathol (2001) 0.78
Secretoneurin promotes pertussis toxin-sensitive neurite outgrowth in cerebellar granule cells. J Neurochem (2003) 0.78
Early induction of secretoneurin expression following kainic acid administration at convulsant doses in the rat and gerbil hippocampus. Hippocampus (2002) 0.76
Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Pediatrics (2005) 5.40
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol (2008) 5.19
IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway. Cell (2007) 4.48
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol (2010) 4.04
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell (2005) 3.89
Growth of large-area and highly crystalline MoS2 thin layers on insulating substrates. Nano Lett (2012) 2.81
Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells. Circulation (2004) 2.69
Adjuvant immunotherapy with whole-cell lysate dendritic cells vaccine for glioblastoma multiforme: a phase II clinical trial. World Neurosurg (2011) 2.24
Endoscopic surgery for intraventricular hemorrhage (IVH) caused by thalamic hemorrhage: comparisons of endoscopic surgery and external ventricular drainage (EVD) surgery. World Neurosurg (2011) 2.21
Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clin Cancer Res (2005) 1.86
Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ (2006) 1.79
Isolation and characterization of size-sieved stem cells from human bone marrow. Stem Cells (2002) 1.62
Mesenchymal stem cells. Cell Transplant (2011) 1.62
Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents. J Med Chem (2002) 1.57
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res (2008) 1.56
Associations between endothelin-1 and adiponectin in chronic heart failure. Cardiology (2011) 1.54
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J Biol Chem (2011) 1.52
Increased risk of urinary tract calculi among patients with diabetes mellitus--a population-based cohort study. Urology (2011) 1.51
Mesenchymal stem cell insights: prospects in cardiovascular therapy. Cell Transplant (2014) 1.50
Risk factors of meconium aspiration syndrome developing into persistent pulmonary hypertension of newborn. Acta Paediatr Taiwan (2004) 1.48
Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1. Am J Pathol (2006) 1.47
Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways. Arterioscler Thromb Vasc Biol (2006) 1.45
Polymorphisms for interleukin 1 beta exon 5 and interleukin 1 receptor antagonist in Taiwanese children with febrile convulsions. Arch Pediatr Adolesc Med (2002) 1.45
Tumor necrosis factor-α gene polymorphisms in age-related macular degeneration. Retina (2010) 1.45
Association of the neuronal nicotinic acetylcholine receptor subunit alpha4 polymorphisms with febrile convulsions. Epilepsia (2003) 1.44
Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents. J Med Chem (2006) 1.42
Preventing iatrogenic injury from inadvertent intracranial migration of a urinary foley catheter while controlling profuse epistaxis after severe craniofacial trauma. J Craniofac Surg (2011) 1.40
Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat Cell Biol (2011) 1.40
Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice. J Mol Med (Berl) (2008) 1.38
Intracerebral peripheral blood stem cell (CD34+) implantation induces neuroplasticity by enhancing beta1 integrin-mediated angiogenesis in chronic stroke rats. J Neurosci (2006) 1.34
Magnetic nanoparticle labeling of mesenchymal stem cells without transfection agent: cellular behavior and capability of detection with clinical 1.5 T magnetic resonance at the single cell level. Magn Reson Med (2007) 1.34
Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats. J Pharmacol Exp Ther (2007) 1.34
The role of human antigen R, an RNA-binding protein, in mediating the stabilization of toll-like receptor 4 mRNA induced by endotoxin: a novel mechanism involved in vascular inflammation. Arterioscler Thromb Vasc Biol (2006) 1.33
Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke (2003) 1.32
Enhancement of neuroplasticity through upregulation of beta1-integrin in human umbilical cord-derived stromal cell implanted stroke model. Neurobiol Dis (2007) 1.28
Mutation analysis of Gaucher disease patients in Taiwan: high prevalence of the RecNciI and L444P mutations. Blood Cells Mol Dis (2006) 1.28
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma. J Neurooncol (2005) 1.25
A multiplexed quantitative strategy for membrane proteomics: opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease. Mol Cell Proteomics (2008) 1.25
F-18 FDG PET/CT in evaluation of pulmonary sclerosing hemangioma. Clin Nucl Med (2011) 1.24
Genome-wide association study of diabetic retinopathy in a Taiwanese population. Ophthalmology (2011) 1.23
Ligand-based dual target drug design for H1N1: swine flu--a preliminary first study. J Biomol Struct Dyn (2009) 1.22
Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Res (2005) 1.21
Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model. J Neurosci (2005) 1.21
RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proc Natl Acad Sci U S A (2010) 1.20
Identification of over-expressed proteins in oral squamous cell carcinoma (OSCC) patients by clinical proteomic analysis. Clin Chim Acta (2006) 1.20
Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells. Carcinogenesis (2009) 1.19
Efficacy of anterior cervical fusion: comparison of titanium cages, polyetheretherketone (PEEK) cages and autogenous bone grafts. J Clin Neurosci (2008) 1.17
Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse. J Neurosci (2005) 1.17
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am J Respir Crit Care Med (2003) 1.16
Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis. Life Sci (2004) 1.16
Focused ultrasound and interleukin-4 receptor-targeted liposomal doxorubicin for enhanced targeted drug delivery and antitumor effect in glioblastoma multiforme. J Control Release (2012) 1.14
Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan. J Biomed Sci (2010) 1.14
The efficacy of quantitative gait analysis by the GAITRite system in evaluation of parkinsonian bradykinesia. Parkinsonism Relat Disord (2006) 1.12
Vascular endothelial growth factor gene polymorphisms in age-related macular degeneration. Am J Ophthalmol (2008) 1.12
Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse. Hum Mol Genet (2009) 1.12
The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo. J Neurochem (2006) 1.12
Establishing a standardized therapeutic testing protocol for spinal muscular atrophy. Neurobiol Dis (2006) 1.11
The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. Clin Cancer Res (2005) 1.10
Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy. Cell Transplant (2015) 1.09
Neuropsychological effects after chronic subthalamic stimulation and the topography of the nucleus in Parkinson's disease. Neurosurgery (2007) 1.07
A statistical method for evaluation quality of medical images: a case study in bit discarding and image compression. Comput Med Imaging Graph (2004) 1.07
RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation. J Cell Biochem (2011) 1.06
Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways. J Cell Physiol (2012) 1.06
Exercise-induced activation of NMDA receptor promotes motor unit development and survival in a type 2 spinal muscular atrophy model mouse. J Neurosci (2008) 1.06
Homing genes, cell therapy and stroke. Front Biosci (2006) 1.06
Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. PLoS One (2012) 1.05
A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells. Gene Expr Patterns (2003) 1.05
Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts. J Appl Physiol (1985) (2011) 1.05
Regenerative therapy for stroke. Cell Transplant (2007) 1.05
EP1- and EP3-receptors mediate prostaglandin E2-induced constriction of porcine large cerebral arteries. J Cereb Blood Flow Metab (2004) 1.05
The induction of orphan nuclear receptor Nur77 expression by n-butylenephthalide as pharmaceuticals on hepatocellular carcinoma cell therapy. Mol Pharmacol (2008) 1.04
Matrix metalloproteinase-9 polymorphism and risk of pelvic organ prolapse in Taiwanese women. Eur J Obstet Gynecol Reprod Biol (2010) 1.03
Neuregulin-1 reduces ischemia-induced brain damage in rats. Neurobiol Aging (2004) 1.03
Antitumor agents 247. New 4-ethoxycarbonylethyl curcumin analogs as potential antiandrogenic agents. Bioorg Med Chem (2006) 1.03
Association of the Slit and Trk-like 1 gene in Taiwanese patients with Tourette syndrome. Pediatr Neurol (2007) 1.03
Bidirectional relation between schizophrenia and epilepsy: a population-based retrospective cohort study. Epilepsia (2011) 1.03
Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells. J Pharmacol Exp Ther (2007) 1.02
Efficient tracking of non-iron-labeled mesenchymal stem cells with serial MRI in chronic stroke rats. Stroke (2006) 1.02