Published in Proc Natl Acad Sci U S A on September 21, 2004
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Cassini dust measurements at Enceladus and implications for the origin of the E ring. Science (2006) 1.83
Extract of the seeds of the plant Vitex agnus castus proven to be highly efficacious as a repellent against ticks, fleas, mosquitoes and biting flies. Parasitol Res (2005) 1.65
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Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis. Plant Physiol (2008) 1.62
Profiling of Arabidopsis secondary metabolites by capillary liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry. Plant Physiol (2004) 1.58
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A reference map of the Arabidopsis thaliana mature pollen proteome. Biochem Biophys Res Commun (2005) 1.36
Interactions between sterol biosynthesis genes in embryonic development of Arabidopsis. Plant J (2002) 1.27
Formation of a complex pattern of sinapate esters in Brassica napus seeds, catalyzed by enzymes of a serine carboxypeptidase-like acyltransferase family? Phytochemistry (2005) 1.26
Why do health systems matter? Exploring links between health systems and HIV response: a case study from Russia. Health Policy Plan (2010) 1.23
How human neuroblastoma cells make morphine. Proc Natl Acad Sci U S A (2005) 1.20
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040. Arch Microbiol (2002) 1.19
1,2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway. Phytochemistry (2004) 1.18
PCR diagnosis of infections with different species of Opisthorchiidae using a rapid clean-up procedure for stool samples and specific primers. Parasitol Res (2006) 1.18
Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. Plant J (2006) 1.17
Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing. Plant Physiol (2004) 1.11
Occurrence and localization of apocarotenoids in arbuscular mycorrhizal plant roots. Plant Cell Physiol (2002) 1.11
Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol (2009) 1.10
Mammalian cytochrome P450 enzymes catalyze the phenol-coupling step in endogenous morphine biosynthesis. J Biol Chem (2009) 1.08
Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins. Phytochemistry (2003) 1.07
Ovicidal effects of a neem seed extract preparation on eggs of body and head lice. Parasitol Res (2011) 1.05
A stilbene synthase gene (SbSTS1) is involved in host and nonhost defense responses in sorghum. Plant Physiol (2005) 1.05
Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. J Med Chem (2005) 1.04
A novel Mg(2+)-dependent O-methyltransferase in the phenylpropanoid metabolism of Mesembryanthemum crystallinum. J Biol Chem (2003) 1.02
Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities. Plant J (2009) 1.01
2-DE proteomic approach to the Botrytis cinerea secretome induced with different carbon sources and plant-based elicitors. Proteomics (2010) 1.01
The Tzs protein from Agrobacterium tumefaciens C58 produces zeatin riboside 5'-phosphate from 4-hydroxy-3-methyl-2-(E)-butenyl diphosphate and AMP. FEBS Lett (2002) 1.01
Serotonin, L-tryptophan, and tryptamine are effective inhibitors of the amino acid transport system PAT1. FASEB J (2005) 1.00
Analgesia: morphine-pathway block in top1 poppies. Nature (2004) 1.00
In vitro and in vivo production of new aminocoumarins by a combined biochemical, genetic, and synthetic approach. Chem Biol (2004) 1.00
Molecular characterization of the homo-phytochelatin synthase of soybean Glycine max: relation to phytochelatin synthase. J Biol Chem (2001) 0.99
Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. Phytochemistry (2006) 0.99
Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited. J Pharmacol Exp Ther (2008) 0.99
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. Eur J Pharm Biopharm (2005) 0.99
Functional characterization of a novel benzylisoquinoline O-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L). Plant J (2009) 0.98
Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics. Phytochemistry (2003) 0.98
Desiccation of the resurrection plant Craterostigma plantagineum induces dynamic changes in protein phosphorylation. Plant Cell Environ (2006) 0.97
Putrescine N-methyltransferase--the start for alkaloids. Phytochemistry (2009) 0.97
Reducing stress on cells with apoferritin-encapsulated platinum nanoparticles. Nano Lett (2010) 0.97
Analysis of phenolic choline esters from seeds of Arabidopsis thaliana and Brassica napus by capillary liquid chromatography/electrospray- tandem mass spectrometry. J Mass Spectrom (2009) 0.95
Profiling of phenylpropanoids in transgenic low-sinapine oilseed rape (Brassica napus). Phytochemistry (2010) 0.94
Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species. Plant J (2009) 0.94
Synthesis of N-(beta-D-glucopyranosyl) monoamides of dicarboxylic acids as potential inhibitors of glycogen phosphorylase. Carbohydr Res (2006) 0.93
Three-dimensional quantitative structure-activity relationship analyses of peptide substrates of the mammalian H+/peptide cotransporter PEPT1. J Med Chem (2003) 0.93
RNA interference-mediated repression of MtCCD1 in mycorrhizal roots of Medicago truncatula causes accumulation of C27 apocarotenoids, shedding light on the functional role of CCD1. Plant Physiol (2008) 0.93
Electrospray tandem mass spectrometric investigations of morphinans. J Am Soc Mass Spectrom (2003) 0.93
An unusual amide synthetase (CouL) from the coumermycin A1 biosynthetic gene cluster from Streptomyces rishiriensis DSM 40489. Eur J Biochem (2003) 0.93
Proteomic profiling of Botrytis cinerea conidial germination. Arch Microbiol (2014) 0.93
Adaptation of Phaeobacter inhibens DSM 17395 to growth with complex nutrients. Proteomics (2013) 0.92
Identification of a disulfide bridge essential for transport function of the human proton-coupled amino acid transporter hPAT1. J Biol Chem (2009) 0.92
Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots. Transgenic Res (2004) 0.92
H+-peptide cotransport in the human bile duct epithelium cell line SK-ChA-1. Am J Physiol Gastrointest Liver Physiol (2002) 0.91
Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1. J Pharmacol Exp Ther (2004) 0.91
Tapetum-specific location of a cation-dependent O-methyltransferase in Arabidopsis thaliana. Plant J (2008) 0.91
A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate. Phytochemistry (2012) 0.90
Modification of soybean sucrose synthase by S-thiolation with ENOD40 peptide A. Biochem Biophys Res Commun (2004) 0.90
Novel candidate genes influencing natural variation in potato tuber cold sweetening identified by comparative proteomics and association mapping. BMC Plant Biol (2013) 0.90
Enhancement of tolerance to heavy metals and oxidative stress in Dunaliella tertiolecta by Zn-induced phytochelatin synthesis. Biochem Biophys Res Commun (2002) 0.89
Evaluation of the mass spectrometric fragmentation of codeine and morphine after 13C-isotope biosynthetic labeling. Phytochemistry (2004) 0.89
A belt of moonlets in Saturn's A ring. Nature (2007) 0.89
A proposed mechanism for the reductive ring opening of the cyclodiphosphate MEcPP, a crucial transformation in the new DXP/MEP pathway to isoprenoids based on modeling studies and feeding experiments. Chembiochem (2004) 0.89
Betulinic acid induces apoptosis in skin cancer cells and differentiation in normal human keratinocytes. Exp Dermatol (2005) 0.88
A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations. Phytochemistry (2003) 0.88
Proteomic analysis of dimorphic transition in the phytopathogenic fungus Ustilago maydis. Proteomics (2007) 0.88
A proteomic analysis of powdery mildew (Blumeria graminis f.sp. hordei) conidiospores. Mol Plant Pathol (2009) 0.88
Assessment of tinnitus-related impairments and disabilities using the German THI-12: sensitivity and stability of the scale over time. Int J Audiol (2011) 0.88
Molecular characterization of root-specific chalcone synthases from Cassia alata. Planta (2002) 0.87
Evolution of morphine biosynthesis in opium poppy. Phytochemistry (2009) 0.87
Analysis of the transport properties of side chain modified dipeptides at the mammalian peptide transporter PEPT1. Eur J Pharm Sci (2004) 0.87
Putrescine N-methyltransferases--a structure-function analysis. Plant Mol Biol (2007) 0.86
Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors. J Biol Chem (2007) 0.86
Distinct pharmacological properties of morphine metabolites at G(i)-protein and β-arrestin signaling pathways activated by the human μ-opioid receptor. Biochem Pharmacol (2011) 0.86
Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1. Biochim Biophys Acta (2008) 0.86
Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars. J Nat Prod (2005) 0.86
Glucosinolates in Moringa stenopetala. Planta Med (2003) 0.85
Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells. Eur J Biochem (2004) 0.85
Protein structure modeling indicates hexahistidine-tag interference with enzyme activity. Proteins (2008) 0.85
Immunocytological localization of two enzymes involved in berberine biosynthesis. Planta (2002) 0.85
[Rapid Sequence Induction in pediatric anesthesia]. Anasthesiol Intensivmed Notfallmed Schmerzther (2007) 0.85
High-affinity interaction of sartans with H+/peptide transporters. Drug Metab Dispos (2008) 0.85
Proteomic analysis of latex from the rubber-producing plant Taraxacum brevicorniculatum. Proteomics (2012) 0.85
Small structural changes of pentacyclic lupane type triterpenoid derivatives lead to significant differences in their anticancer properties. Eur J Med Chem (2010) 0.84
The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1. Mol Pharm (2009) 0.84
Overexpression of tropinone reductases alters alkaloid composition in Atropa belladonna root cultures. J Exp Bot (2005) 0.84
Transport of free and peptide-bound pyrraline at intestinal and renal epithelial cells. J Agric Food Chem (2009) 0.84
The effect of polyelectrolyte multilayer coated titanium alloy surfaces on implant anchorage in rats. Acta Biomater (2012) 0.84
Colorimetric activity measurement of a recombinant putrescine N-methyltransferase from Datura stramonium. Planta Med (2006) 0.84
Flavonols and an indole alkaloid skeleton bearing identical acylated glycosidic groups from yellow petals of Papaver nudicaule. Phytochemistry (2005) 0.83
Analysis of desiccation-induced candidate phosphoproteins from Craterostigma plantagineum isolated with a modified metal oxide affinity chromatography procedure. Proteomics (2008) 0.83
Structural requirements for the substrates of the H+/peptide cotransporter PEPT2 determined by three-dimensional quantitative structure-activity relationship analysis. J Med Chem (2006) 0.83
Large-scale proteomic analysis of the grapevine leaf apoplastic fluid reveals mainly stress-related proteins and cell wall modifying enzymes. BMC Plant Biol (2013) 0.83
Molecular cloning, expression and characterization of tropinone reductase II, an enzyme of the SDR family in Solanum tuberosum (L.). Plant Mol Biol (2002) 0.83
Hygrophorones A-G: fungicidal cyclopentenones from Hygrophorus species (Basidiomycetes). Phytochemistry (2004) 0.83
Accumulation of apocarotenoids in mycorrhizal roots of Ornithogalum umbellatum. Phytochemistry (2006) 0.83