Published in Acta Crystallogr Sect F Struct Biol Cryst Commun on February 24, 2006
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
The nuclear genome of Rhazya stricta and the evolution of alkaloid diversity in a medically relevant clade of Apocynaceae. Sci Rep (2016) 0.77
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants. Nat Biotechnol (2005) 3.39
In planta engineering of viral RNA replicons: efficient assembly by recombination of DNA modules delivered by Agrobacterium. Proc Natl Acad Sci U S A (2004) 2.77
The terminal O-acetyltransferase involved in vindoline biosynthesis defines a new class of proteins responsible for coenzyme A-dependent acyl transfer. Plant J (1998) 2.00
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. Proc Natl Acad Sci U S A (2000) 1.48
Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum. J Biol Chem (2001) 1.36
Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J Biol Chem (2005) 1.26
How human neuroblastoma cells make morphine. Proc Natl Acad Sci U S A (2005) 1.20
Endogenous formation of morphine in human cells. Proc Natl Acad Sci U S A (2004) 1.12
Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids. Eur J Biochem (2002) 1.08
Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochim Biophys Acta (2004) 0.97
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis. Phytochemistry (2000) 0.94
Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Biochim Biophys Acta (2004) 0.92
Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system. Planta (2005) 0.88
On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr D Biol Crystallogr (2007) 1.78
Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. J Am Chem Soc (2008) 1.50
Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries. Chem Biol (2007) 1.46
Automated technologies and novel techniques to accelerate protein crystallography for structural genomics. Proteomics (2008) 1.43
The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis. J Biol Chem (2006) 1.34
The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. Plant Cell (2006) 1.32
On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength. Acta Crystallogr D Biol Crystallogr (2005) 1.30
C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain. J Mol Biol (2008) 1.28
Crystal structure of vinorine synthase, the first representative of the BAHD superfamily. J Biol Chem (2005) 1.26
Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage. Bioorg Med Chem (2009) 1.16
Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids. Eur J Biochem (2002) 1.08
On the influence of the incident photon energy on the radiation damage in crystalline biological samples. J Synchrotron Radiat (2005) 1.07
Structure of the motor subunit of type I restriction-modification complex EcoR124I. Nat Struct Mol Biol (2008) 1.06
Structural insights into the mechanism of protein O-fucosylation. PLoS One (2011) 1.06
Cyanuric acid hydrolase: evolutionary innovation by structural concatenation. Mol Microbiol (2013) 1.06
Molecular architecture of strictosidine glucosidase: the gateway to the biosynthesis of the monoterpenoid indole alkaloid family. Plant Cell (2007) 1.05
Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum. Structure (2008) 1.05
3D-Structure and function of strictosidine synthase--the key enzyme of monoterpenoid indole alkaloid biosynthesis. Plant Physiol Biochem (2008) 1.02
Structural and functional aspects of the sensor histidine kinase PrrB from Mycobacterium tuberculosis. Structure (2006) 1.02
The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature (2013) 1.00
The crystal structure of the herpes simplex virus 1 ssDNA-binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J Biol Chem (2004) 1.00
New alkaloids of the sarpagine group from Rauvolfia serpentina hairy root culture. J Nat Prod (2002) 1.00
Acetyltransfer in natural product biosynthesis--functional cloning and molecular analysis of vinorine synthase. Bioorg Med Chem (2004) 0.99
Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc Natl Acad Sci U S A (2012) 0.98
Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochim Biophys Acta (2004) 0.97
The three-dimensional structure of the extracellular adhesion domain of the sialic acid-binding adhesin SabA from Helicobacter pylori. J Biol Chem (2013) 0.96
A facile chemoenzymatic approach: one-step syntheses of monoterpenoid indole alkaloids. Chem Asian J (2010) 0.96
Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex. EMBO J (2011) 0.96
Crystal structures of a poplar thioredoxin peroxidase that exhibits the structure of glutathione peroxidases: insights into redox-driven conformational changes. J Mol Biol (2007) 0.96
Arbutin synthase, a novel member of the NRD1beta glycosyltransferase family, is a unique multifunctional enzyme converting various natural products and xenobiotics. Bioorg Med Chem (2002) 0.93
Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Biochim Biophys Acta (2004) 0.92
Structural basis for the oxidation of protein-bound sulfur by the sulfur cycle molybdohemo-enzyme sulfane dehydrogenase SoxCD. J Biol Chem (2010) 0.91
The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae. J Struct Biol (2012) 0.90
Crystallization and preliminary X-ray analysis of strictosidine synthase and its complex with the substrate tryptamine. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers. J Mol Biol (2007) 0.89
Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system. Planta (2005) 0.88
The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J Biol Chem (2007) 0.88
High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor. Acta Biochim Pol (2007) 0.88
Trends for diverse production strategies of plant medicinal alkaloids. Nat Prod Rep (2010) 0.88
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.86
Structure of lambda CII: implications for recognition of direct-repeat DNA by an unusual tetrameric organization. Proc Natl Acad Sci U S A (2005) 0.85
High-resolution structure of Bombyx mori lipoprotein 7: crystallographic determination of the identity of the protein and its potential role in detoxification. Acta Crystallogr D Biol Crystallogr (2012) 0.85
Metal binding to porcine pancreatic elastase: calcium or not calcium. Acta Crystallogr D Biol Crystallogr (2002) 0.85
Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.85
On the routine use of soft X-rays in macromolecular crystallography. Part II. Data-collection wavelength and scaling models. Acta Crystallogr D Biol Crystallogr (2003) 0.85
Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX. Acta Crystallogr D Biol Crystallogr (2013) 0.84
Structural characterization of the multidomain regulatory protein Rv1364c from Mycobacterium tuberculosis. Structure (2011) 0.84
On the routine use of soft X-rays in macromolecular crystallography. Part V. Molecular replacement and anomalous scattering. Acta Crystallogr D Biol Crystallogr (2011) 0.83
Additional phase information from UV damage of selenomethionine labelled proteins. J Synchrotron Radiat (2011) 0.83
Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity. J Struct Biol (2011) 0.83
Preparation of C-23 esterified silybin derivatives and evaluation of their lipid peroxidation inhibitory and DNA protective properties. Bioorg Med Chem (2009) 0.83
Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia. Plant Mol Biol (2008) 0.83
Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids. Angew Chem Int Ed Engl (2009) 0.82
A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis. J Biol Chem (2006) 0.82
Scaffold tailoring by a newly detected Pictet-Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework. J Am Chem Soc (2012) 0.81
Purification, crystallization and preliminary X-ray analysis of the HsdR subunit of the EcoR124I endonuclease from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.81
Structures of alkaloid biosynthetic glucosidases decode substrate specificity. ACS Chem Biol (2011) 0.81
Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli. Protein Sci (2008) 0.81
Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis. J Struct Funct Genomics (2009) 0.81
Structural insight in histo-blood group binding by the F18 fimbrial adhesin FedF. Mol Microbiol (2012) 0.81
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochim Biophys Acta (2004) 0.81
Design, synthesis, and SAR analysis of cytotoxic sinapyl alcohol derivatives. Bioorg Med Chem (2005) 0.79
Structural biology in plant natural product biosynthesis--architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis. Nat Prod Rep (2007) 0.79
The X-ray structure of the N-terminal domain of PILB from Neisseria meningitidis reveals a thioredoxin-fold. J Mol Biol (2006) 0.79
Synthesis, biological evaluation, and structure-activity relationship study of novel cytotoxic aza-caffeic acid derivatives. Bioorg Med Chem (2010) 0.79
Chemotherapeutic effects of bioassay-guided extracts of the American cockroach, Periplaneta americana. Integr Cancer Ther (2011) 0.79
Vomilenine reductase--a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline. Bioorg Med Chem (2002) 0.78
A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline. Planta Med (2002) 0.78
Structure of the C-terminal domain of nsp4 from feline coronavirus. Acta Crystallogr D Biol Crystallogr (2009) 0.78
In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures. J Struct Biol (2012) 0.78
Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis. Eur J Biochem (2002) 0.78
Purification, crystallization and X-ray diffraction analysis of pavine N-methyltransferase from Thalictrum flavum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.77
Probing suggested catalytic domains of glycosyltransferases by site-directed mutagenesis. Eur J Biochem (2003) 0.77
Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production. Biotechnol Rep (Amst) (2014) 0.77
Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis. PLoS One (2013) 0.77
In vivo monitoring of alkaloid metabolism in hybrid plant cell cultures by 2D cryo-NMR without labelling. Bioorg Med Chem (2003) 0.77
"One-pot" multicomponent approach to indolizines and pyrido[1,2-a]indoles. Org Lett (2011) 0.77
The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules. J Struct Biol (2011) 0.77
Improved expression of His(6)-tagged strictosidine synthase cDNA for chemo-enzymatic alkaloid diversification. Chem Biodivers (2010) 0.77
Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling. Acta Crystallogr D Biol Crystallogr (2012) 0.77
Post-translational modification and extended glycosylation pattern of a plant latex peroxidase of native source characterized by X-ray crystallography. FEBS J (2014) 0.76
Purification and partial amino acid sequences of the enzyme vinorine synthase involved in a crucial step of ajmaline biosynthesis. Bioorg Med Chem (2004) 0.76
Diarylheptanoids and a monoterpenoid from the rhizomes of Zingiber officinale: antioxidant and cytoprotective properties. J Nat Prod (2008) 0.76
Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding. J Biol Chem (2012) 0.76
The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces. Acta Crystallogr D Biol Crystallogr (2009) 0.76
Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY from Chlorobium limicola f. thiosulfatophilum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.76