The protein kinase C-related PKC-L(eta) gene product is localized in the cell nucleus.

PubWeight™: 0.92‹?›

🔗 View Article (PMC 369563)

Published in Mol Cell Biol on March 01, 1992

Authors

H Greif1, J Ben-Chaim, T Shimon, E Bechor, H Eldar, E Livneh

Author Affiliations

1: Department of Chemical Immunology, Weizmann Institute of Science, Rehovot, Israel.

Articles cited by this

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell (1987) 20.61

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82

Studies and perspectives of protein kinase C. Science (1986) 14.73

The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature (1988) 14.43

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell (1988) 7.76

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell (1991) 6.89

Phorbol diester receptor copurifies with protein kinase C. Proc Natl Acad Sci U S A (1983) 6.25

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science (1986) 6.10

Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (1988) 5.18

Cloning and expression of multiple protein kinase C cDNAs. Cell (1986) 4.23

The structure, expression, and properties of additional members of the protein kinase C family. J Biol Chem (1988) 4.15

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein. Cell (1985) 4.02

The complete primary structure of protein kinase C--the major phorbol ester receptor. Science (1986) 4.02

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells. Biochem Biophys Res Commun (1984) 3.44

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties. Proc Natl Acad Sci U S A (1989) 3.21

A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family. Cell (1988) 2.44

Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol. Proc Natl Acad Sci U S A (1983) 2.23

Down-regulation of protein kinase C is due to an increased rate of degradation. Biochem J (1987) 2.14

Tissue-specific expression of three distinct types of rabbit protein kinase C. Nature (1987) 2.14

A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. J Biol Chem (1990) 2.12

Lipid activation of protein kinase C. J Biol Chem (1991) 1.99

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes. Nature (1987) 1.93

Large deletions in the cytoplasmic kinase domain of the epidermal growth factor receptor do not affect its laternal mobility. J Cell Biol (1986) 1.82

Two types of complementary DNAs of rat brain protein kinase C. Heterogeneity determined by alternative splicing. FEBS Lett (1986) 1.59

Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family. Proc Natl Acad Sci U S A (1987) 1.59

Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C. J Biol Chem (1988) 1.52

Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells. J Cell Biol (1989) 1.48

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol Cell Biol (1991) 1.47

Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res (1983) 1.42

Identification of a calcium- and phospholipid- dependent phorbol ester binding activity in the soluble fraction of mouse tissues. Biochem Biophys Res Commun (1983) 1.34

Abundant nuclear ribonucleoprotein form of CAD RNA. Mol Cell Biol (1985) 1.30

Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells. J Biol Chem (1991) 1.26

Immunological evidence for two physiological forms of protein kinase C. Mol Cell Biol (1987) 1.19

Protein kinase C heterogeneity in GH4C1 rat pituitary cells. Characterization of a Ca2(+)-independent phorbol ester receptor. J Biol Chem (1990) 1.17

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters. J Biol Chem (1991) 1.13

Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester. FEBS Lett (1988) 1.07

Overexpression of protein kinase C alpha-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor. J Biol Chem (1990) 1.06

Differential down-regulation of protein kinase C subspecies in KM3 cells. FEBS Lett (1988) 1.04

Phorbol ester-mediated association of protein kinase C to the nuclear fraction in NIH 3T3 cells. Cancer Res (1988) 0.99

Rat liver nuclei protein kinase C is the isozyme type II. J Biol Chem (1990) 0.94

Evidence for metastatic heterogeneity of human renal cell carcinoma. Anticancer Res (1989) 0.79

Articles by these authors

Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. J Biol Chem (1986) 2.78

Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization. EMBO J (1986) 2.38

Large deletions in the cytoplasmic kinase domain of the epidermal growth factor receptor do not affect its laternal mobility. J Cell Biol (1986) 1.82

The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains. Cell (1985) 1.76

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol Cell Biol (1991) 1.47

Penile length in adulthood after exstrophy reconstruction. J Urol (1997) 1.10

Overexpression of epidermal growth factor receptor in NIH-3T3-transfected cells slows its lateral diffusion and rate of endocytosis. J Cell Biol (1988) 1.08

Overexpression of protein kinase C alpha-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor. J Biol Chem (1990) 1.06

Development of a large bladder calculus on sutures used for pubic bone closure following extrophy repair. World J Urol (2001) 1.05

Protein kinase C group B members PKC-delta, -epsilon, -zeta and PKC-L(eta). Comparison of properties of recombinant proteins in vitro and in vivo. Biochem J (1992) 1.01

Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase C alpha. J Biol Chem (1993) 0.98

A combined vertical and horizontal pelvic osteotomy approach for primary and secondary repair of bladder exstrophy. J Urol (1996) 0.97

The role of protein kinase C in G1 and G2/M phases of the cell cycle (review). Int J Oncol (1998) 0.95

Molecular modeling based mutagenesis defines ligand binding and specificity determining regions of fibroblast growth factor receptors. Biochemistry (1995) 0.91

Linking protein kinase C to the cell cycle: ectopic expression of PKC eta in NIH3T3 cells alters the expression of cyclins and Cdk inhibitors and induces adipogenesis. Oncogene (1996) 0.90

Up-regulation of phospholipase D activity induced by overexpression of protein kinase C-alpha. Studies in intact Swiss/3T3 cells and in detergent-solubilized membranes in vitro. J Biol Chem (1993) 0.88

Hyperthyroidism results in increased glycolytic capacity in the rat heart. A 31P-NMR study. Biochim Biophys Acta (1990) 0.88

PKCeta enhances cell cycle progression, the expression of G1 cyclins and p21 in MCF-7 cells. Oncogene (2001) 0.87

Criteria for the prenatal diagnosis of classic bladder exstrophy. Obstet Gynecol (1995) 0.87

Temporal analysis of connexin43 protein and gene expression throughout the menstrual cycle in human endometrium. Fertil Steril (2000) 0.87

The multiple reoperative bladder exstrophy closure: what affects the potential of the bladder? Urology (1996) 0.86

The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene. J Biol Chem (1996) 0.85

Chemotherapy-induced changes in the energetics of human breast cancer cells; 31P- and 13C-NMR studies. Biochim Biophys Acta (1990) 0.84

Crystallization of a DNA tridecamer d(C-G-C-A-G-A-A-T-T-C-G-C-G). J Mol Biol (1986) 0.84

Activation of HTLV-I long terminal repeat by stress-inducing agents and protection of HTLV-I-infected T-cells from apoptosis by the viral tax protein. Exp Cell Res (2001) 0.84

The Cantwell-Ransley epispadias repair in exstrophy and epispadias: lessons learned. Urology (1995) 0.81

Phospholipase D-mediated hydrolysis of phosphatidylcholine: role in cell signalling. J Lipid Mediat (1993) 0.81

Increased serum alkaline phosphatase activity: a possible indicator of renal damage. J Clin Lab Anal (1991) 0.81

Upper pole heminephrectomy for duplex systems in children: a modified technical approach. Br J Urol (1994) 0.81

The significance of ureteral obstruction in invasive transitional cell carcinoma of the urinary bladder. J Surg Oncol (1993) 0.80

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol Cell Biol (1992) 0.80

Regulation of amyloid precursor protein release by protein kinase C in Swiss 3T3 fibroblasts. Ann N Y Acad Sci (1993) 0.79

Expression of PKCeta in NIH-3T3 cells promotes production of the pro-inflammatory cytokine interleukin-6. Eur Cytokine Netw (1999) 0.79

Light-induced free-radical reactions of purines and pyrimidines in deoxyribonucleic acid. Effect of structure and base sequence on reactivity. Biochemistry (1982) 0.79

Deletions in the regulatory or kinase domains of protein kinase C-alpha cause association with the cell nucleus. Exp Cell Res (1992) 0.78

Bladder neck closure with an Indiana stoma outlet as a technique for continent vesicostomy. Surg Gynecol Obstet (1993) 0.77

Light-induced free-radical reactions of nucleic acid constituents. Effect of sequence and base--base interactions on the reactivity of purines and pyrimidines in ribonucleotides. Biochemistry (1978) 0.77

Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha. Biochem J (1995) 0.76

The expression of PDGF-alpha but not PDGF-beta receptors is suppressed in Swiss/3T3 fibroblasts over-expressing protein kinase C-alpha. FEBS Lett (1994) 0.76

Vesicoureteral reflux and lower urinary tract injury: the possible role of suprapubic cystostomy. J Urol (1993) 0.75

Is it justified to avoid radical cystoprostatectomy in elderly patients with invasive transitional cell carcinoma of the bladder? Cancer (1993) 0.75

Conservative treatment of a vesicocervical fistula resulting from Shirodkar cervical cerclage. J Urol (1993) 0.75

Phosphorylation of p90 and p52 in response to phorbol-esters in Swiss/3T3 cells overexpressing protein kinase C-alpha. Mol Biol Cell (1992) 0.75

Specific photoalkylation of poly U and of poly A with 2-propanol and their messenger properties. Photochem Photobiol (1980) 0.75

Ureteropelvic junction obstruction in the first year of life. J Pediatr (1991) 0.75

Augmentation ureterocystoplasty: is it the preferred choice? East Afr Med J (2005) 0.75

Pitfalls in the detection of urinary extravasation following major urinary tract reconstructive surgery. Urol Int (1995) 0.75

[Endometriosis of the bladder]. Harefuah (1993) 0.75

Specific regulation of the 100 kDa 2-5 A synthetase by protein kinase C. Eur Cytokine Netw (1992) 0.75

Identification and localization of photoalkylated bases in DNA fragments. Photochem Photobiol (1986) 0.75

Glide wires for delayed catheterization of severely obstructed ureters. Eur Urol (2000) 0.75

Superprecipitation of heavy meromyosin with aggregated F-actin. FEBS Lett (1979) 0.75

Early experience with telerobotic surgery in children. J Telemed Telecare (1996) 0.75