Published in Endocr Res on May 01, 2004
Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol (2007) 2.13
Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. PLoS One (2009) 1.67
Deletion of cd39/entpd1 results in hepatic insulin resistance. Diabetes (2008) 1.18
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. J Clin Invest (2011) 1.15
Metabolic characteristics of long-lived mice. Front Genet (2012) 1.04
Protein kinase Cβ deficiency attenuates obesity syndrome of ob/ob mice by promoting white adipose tissue remodeling. J Lipid Res (2011) 0.91
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression. Diabetologia (2009) 0.85
Disruption of the murine protein kinase Cbeta gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolism. J Biol Chem (2011) 0.81
In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography. J Oncol (2009) 0.76
Role of PKCbeta in hepatocellular carcinoma cells migration and invasion in vitro: a potential therapeutic target. Clin Exp Metastasis (2008) 0.76
IGF-1 Receptor Insufficiency Leads to Age-Dependent Attenuation of Osteoblast Differentiation. Endocrinology (2015) 0.75
PKCβ: Expanding role in hepatic adaptation of cholesterol homeostasis to dietary fat/cholesterol. Am J Physiol Gastrointest Liver Physiol (2017) 0.75
Retracted Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial. Lancet (2003) 7.69
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods (2005) 2.70
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat Med (2002) 2.61
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol Cell Biol (2004) 1.95
EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis. Mol Cell (2009) 1.82
Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy. Anal Chem (2007) 1.74
Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J (2003) 1.53
Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport. J Biol Chem (2002) 1.52
Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression. Biochim Biophys Acta (2002) 1.49
Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases. Nat Prod Rep (2010) 1.47
Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment. Circulation (2004) 1.44
Pulmonary Mycobacterium avium complex infection in patients with panhypopituitarism not receiving hormone replacement therapy. Mayo Clin Proc (2005) 1.42
Knockout of PKC alpha enhances insulin signaling through PI3K. Mol Endocrinol (2002) 1.42
Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest (2007) 1.40
Physiologic roles of 11beta-hydroxysteroid dehydrogenase type 2 in kidney. Metabolism (2006) 1.40
Prognostic impact of left ventricular noncompaction in patients with Duchenne/Becker muscular dystrophy--prospective multicenter cohort study. Int J Cardiol (2013) 1.40
Inverse Correlation Between Calcium Accumulation and the Expansion Rate of Abdominal Aortic Aneurysms. Circ J (2015) 1.38
Depressive state and paresthesia dramatically improved by intravenous MgSO4 in Gitelman's syndrome. Intern Med (2004) 1.38
Relationships between Causes of Fever of Unknown Origin and Inflammatory Markers: A Multicenter Collaborative Retrospective Study. Intern Med (2015) 1.38
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice. Cancer Res (2004) 1.36
The Japanese national health screening and intervention program aimed at preventing worsening of the metabolic syndrome. Int Heart J (2008) 1.30
Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice. Mol Endocrinol (2004) 1.26
The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression. Circ Res (2009) 1.20
A plant type III polyketide synthase that produces pentaketide chromone. J Am Chem Soc (2005) 1.14
Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1. Diabetes (2004) 1.13
Somatic mutations in cerebral cortical malformations. N Engl J Med (2014) 1.10
Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth. Mol Cell Biol (2006) 1.09
Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens. Int Heart J (2005) 1.07
PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes. J Clin Endocrinol Metab (2002) 1.05
Circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 are associated with early carotid atherosclerosis. Arterioscler Thromb Vasc Biol (2004) 1.04
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice. Nat Genet (2009) 1.03
Protein kinase C-lambda knockout in embryonic stem cells and adipocytes impairs insulin-stimulated glucose transport. Mol Endocrinol (2003) 1.03
Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Diabetes (2002) 1.03
Muscle hematoma: a critically important complication of alcoholic liver cirrhosis. World J Gastroenterol (2009) 0.99
Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese. Int J Cardiol (2003) 0.98
A novel channelopathy in pulmonary arterial hypertension. N Engl J Med (2013) 0.98
Effect of royal jelly ingestion for six months on healthy volunteers. Nutr J (2012) 0.97
The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts. J Am Coll Cardiol (2002) 0.97
Predictors of mortality after emergency or elective repair of abdominal aortic aneurysm in a Japanese population. Heart Vessels (2012) 0.97
An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata. FEBS J (2007) 0.96
Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C. Antioxid Redox Signal (2010) 0.96
High glucose inhibits apoptosis in human coronary artery smooth muscle cells by increasing bcl-xL and bfl-1/A1. Am J Physiol Cell Physiol (2002) 0.95
Engineered biosynthesis of plant polyketides: manipulation of chalcone synthase. Org Lett (2006) 0.94
Structure function analysis of benzalacetone synthase from Rheum palmatum. Bioorg Med Chem Lett (2007) 0.93
Granulocyte colony-stimulating factor: a noninvasive regeneration therapy for treating atherosclerotic peripheral artery disease. Circ J (2006) 0.92
Effect of fasting on PPARgamma and AMPK activity in adipocytes. Diabetes Res Clin Pract (2008) 0.92
Associations of body size and reproductive factors with circulating levels of sex hormones and prolactin in premenopausal Japanese women. Cancer Causes Control (2011) 0.91
The metabolic syndrome and DYRK1B. N Engl J Med (2014) 0.91
Actin -related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats. Mamm Genome (2007) 0.89
Effect of granulocyte colony-stimulating factor treatment at a low dose but for a long duration in patients with coronary heart disease. Circ J (2006) 0.89
Defective Activation of Protein Kinase C-z in Muscle by Insulin and Phosphatidylinositol-3,4,5,-(PO(4))(3) in Obesity and Polycystic Ovary Syndrome. Metab Syndr Relat Disord (2004) 0.89
Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes. Endocrinology (2003) 0.89
Hydrogen bond directed self-assembly of core-substituted naphthalene bisimides with melamines in solution and at the graphite interface. Org Biomol Chem (2004) 0.89
Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period. J Biol Chem (2013) 0.89
Diagnostic workup for fever of unknown origin: a multicenter collaborative retrospective study. BMJ Open (2013) 0.88
Hyperglycemic chorea-ballism or acute exacerbation of Huntington's chorea? Huntington's disease unmasked by diabetic ketoacidosis in type 1 diabetes mellitus. J Clin Endocrinol Metab (2012) 0.88
Cytotoxic tetramic acid derivative produced by a plant type-III polyketide synthase. J Am Chem Soc (2011) 0.88
Speckle tracking global strain rate E/E' predicts LV filling pressure more accurately than traditional tissue Doppler E/E'. Echocardiography (2011) 0.88
Lindera strychnifolia is protective against post-ischemic myocardial dysfunction through scavenging hydroxyl radicals and opening the mitochondrial KATP channels in isolated rat hearts. Am J Chin Med (2004) 0.88
Transient Graves disease developing after surgery for Cushing disease. Am J Med Sci (2002) 0.87
Glycosaminoglycans in the blood of hereditary multiple exostoses patients: Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application. Glycobiology (2013) 0.87
Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease. Clin Chim Acta (2011) 0.86
Effects of intratympanic injection of steroids on changes in rat inner ear aquaporin expression. Acta Otolaryngol (2002) 0.86
Structure-based engineering of a plant type III polyketide synthase: formation of an unnatural nonaketide naphthopyrone. J Am Chem Soc (2007) 0.86
Inhibitory effect of ceramide on insulin-induced protein kinase Czeta translocation in rat adipocytes. Metabolism (2003) 0.86
Prenylation of a nonaromatic carbon of indolylbutenone by a fungal indole prenyltransferase. Org Lett (2012) 0.85
Increased atypical PKC activity in endurance-trained human skeletal muscle. Biochem Biophys Res Commun (2003) 0.85
Associations of intakes of fat, dietary fiber, soy isoflavones, and alcohol with levels of sex hormones and prolactin in premenopausal Japanese women. Cancer Causes Control (2012) 0.85
Adverse cardiovascular outcomes associated with concurrent use of clopidogrel or ticlopidine and proton-pump inhibitors in patients undergoing percutaneous coronary intervention. Heart Vessels (2012) 0.85
Inverse association between the existence of coronary artery disease and progression of abdominal aortic aneurysm. Atherosclerosis (2012) 0.85
Cbl, IRS-1, and IRS-2 mediate effects of rosiglitazone on PI3K, PKC-lambda, and glucose transport in 3T3/L1 adipocytes. Endocrinology (2002) 0.84
Lifestyle and health factors associated with stress urinary incontinence in Japanese women. Maturitas (2010) 0.84
Mouse brain IgG-like immunoreactivity: strain-specific occurrence in microglia and biochemical identification of IgG. J Comp Neurol (2005) 0.84
Up-regulation of cochlear aquaporin-3 mRNA expression after intra-endolymphatic sac application of dexamethasone. Neurol Res (2003) 0.84
Association of intakes of fat, dietary fibre, soya isoflavones and alcohol with uterine fibroids in Japanese women. Br J Nutr (2009) 0.84
Evaluating Japanese patients with the Marfan syndrome using high-throughput microarray-based mutational analysis of fibrillin-1 gene. Am J Cardiol (2011) 0.84
Cilnidipine, an N+L-type dihydropyridine Ca channel blocker, suppresses the occurrence of ischemia/reperfusion arrhythmia in a rabbit model of myocardial infarction. Hypertens Res (2005) 0.84
Prediction of coronary artery stenosis using strain imaging diastolic index at rest in patients with preserved ejection fraction. J Cardiol (2011) 0.84
Spectral pattern of urinary water as a biomarker of estrus in the giant panda. Sci Rep (2012) 0.83
Association of dietary fat, vegetables and antioxidant micronutrients with skin ageing in Japanese women. Br J Nutr (2010) 0.83
Dehydroepiandrosterone down-regulates the expression of peroxisome proliferator-activated receptor gamma in adipocytes. Endocrinology (2003) 0.83
Changes in aquaporin expression in the inner ear of the rat after i.p. injection of steroids. Acta Otolaryngol Suppl (2004) 0.83