Published in J Biol Chem on October 21, 2004
Efflux-mediated antifungal drug resistance. Clin Microbiol Rev (2009) 2.44
Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants. Antimicrob Agents Chemother (2006) 1.70
A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Proc Natl Acad Sci U S A (2008) 1.48
Genome-wide expression and location analyses of the Candida albicans Tac1p regulon. Eukaryot Cell (2007) 1.35
Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot Cell (2007) 1.35
Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility. Antimicrob Agents Chemother (2006) 1.25
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. Antimicrob Agents Chemother (2008) 1.01
Fungal PDR transporters: Phylogeny, topology, motifs and function. Fungal Genet Biol (2009) 0.98
Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor. Mol Microbiol (2012) 0.91
Regulation of ABC transporter function via phosphorylation by protein kinases. Curr Pharm Biotechnol (2011) 0.86
The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata. J Biol Chem (2011) 0.82
Positive regulation of the Candida albicans multidrug efflux pump Cdr1p function by phosphorylation of its N-terminal extension. J Antimicrob Chemother (2016) 0.76
Novel autophagy inducers lentztrehaloses A, B and C. J Antibiot (Tokyo) (2015) 0.75
Efflux-mediated antifungal drug resistance. Clin Microbiol Rev (2009) 2.44
Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. Biochem Biophys Res Commun (2005) 1.65
Candida albicans drug resistance another way to cope with stress. Microbiology (2007) 1.35
Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot Cell (2007) 1.35
ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates. Antimicrob Agents Chemother (2008) 1.30
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc Natl Acad Sci U S A (2014) 1.23
Sixty alleles of the ALS7 open reading frame in Candida albicans: ALS7 is a hypermutable contingency locus. Genome Res (2003) 1.23
Antifungal drug resistance of oral fungi. Odontology (2010) 1.21
Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. Mol Microbiol (2006) 1.16
Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. J Biol Chem (2002) 1.16
Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther (2004) 1.12
β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D. PLoS One (2011) 1.10
Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance. J Antimicrob Chemother (2004) 1.08
Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p. Anal Biochem (2009) 1.08
Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway. Mol Cancer Ther (2002) 1.07
Candida glabrata ATP-binding cassette transporters Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporters show phosphorylation-dependent pumping properties. J Biol Chem (2002) 1.05
Morphotypic conversion in Listeria monocytogenes biofilm formation: biological significance of rough colony isolates. Appl Environ Microbiol (2004) 1.05
Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma. J Allergy Clin Immunol (2012) 1.04
BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors. Mol Cancer Ther (2004) 1.03
Ets-1-dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus through interaction with Daxx. J Biol Chem (2006) 1.03
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. Antimicrob Agents Chemother (2008) 1.01
Inhibition of fungal ABC transporters by unnarmicin A and unnarmicin C, novel cyclic peptides from marine bacterium. Biochem Biophys Res Commun (2007) 1.00
Candida albicans protein kinase CaHsl1p regulates cell elongation and virulence. Mol Microbiol (2005) 1.00
Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 1.00
Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance. Antimicrob Agents Chemother (2005) 1.00
Tandem affinity purification of the Candida albicans septin protein complex. Yeast (2004) 0.99
Detection of environmental sources of Histoplasma capsulatum in Chiang Mai, Thailand, by nested PCR. Mycopathologia (2013) 0.99
Fungal PDR transporters: Phylogeny, topology, motifs and function. Fungal Genet Biol (2009) 0.98
Novel approach to designing primers for identification and distinction of the human pathogenic fungi Coccidioides immitis and Coccidioides posadasii by PCR amplification. J Clin Microbiol (2006) 0.98
Biosynthesis of hibarimicins. I. 13C-labeling experiments. J Antibiot (Tokyo) (2002) 0.98
Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. J Biol Chem (2004) 0.97
The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum. J Antimicrob Chemother (2007) 0.96
Biosynthesis of hibarimicins. II. Elucidation of biosynthetic pathway by cosynthesis using blocked mutants. J Antibiot (Tokyo) (2002) 0.95
Construction of FLAG tagging vectors for Candida albicans. Yeast (2002) 0.95
Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans. Infect Immun (2006) 0.94
Biosynthesis of hibarimicins. III. Structures of new hibarimicin-related metabolites produced by blocked mutants. J Antibiot (Tokyo) (2002) 0.94
Construction of a pair of practical Nocardia-Escherichia coli shuttle vectors. Jpn J Infect Dis (2007) 0.93
Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. J Immunol (2008) 0.93
The metabolic basis of Candida albicans morphogenesis and quorum sensing. Fungal Genet Biol (2011) 0.93
Cyclic AMP inhibits translation of cyclin D3 in T lymphocytes at the level of elongation by inducing eEF2-phosphorylation. Cell Signal (2003) 0.91
Trichosporon species isolated from guano samples obtained from bat-inhabited caves in Japan. Appl Environ Microbiol (2005) 0.91
Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor. Mol Microbiol (2012) 0.91
The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates. Antimicrob Agents Chemother (2011) 0.90
Construction and functional analysis of fatty acid desaturase gene disruptants in Candida albicans. Microbiology (2006) 0.90
Chimeras of Candida albicans Cdr1p and Cdr2p reveal features of pleiotropic drug resistance transporter structure and function. Mol Microbiol (2011) 0.89
Effects of hibarimicins and hibarimicin-related compounds produced by Microbispora on v-Src kinase activity and growth and differentiation of human myeloid leukemia HL-60 cells. J Antibiot (Tokyo) (2002) 0.89