Published in J Biol Chem on August 01, 2002
Cell cycle regulation by the NEK family of protein kinases. J Cell Sci (2012) 1.64
NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint. Nat Cell Biol (2009) 1.55
A NIMA-related kinase, Fa2p, localizes to a novel site in the proximal cilia of Chlamydomonas and mouse kidney cells. Mol Biol Cell (2004) 1.44
The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis. BMC Cell Biol (2008) 1.23
Active Nercc1 protein kinase concentrates at centrosomes early in mitosis and is necessary for proper spindle assembly. Mol Biol Cell (2005) 1.17
Repressing the expression of the SUCROSE NONFERMENTING-1-RELATED PROTEIN KINASE gene in pea embryo causes pleiotropic defects of maturation similar to an abscisic acid-insensitive phenotype. Plant Physiol (2005) 1.17
TopBP1 controls BLM protein level to maintain genome stability. Mol Cell (2013) 1.04
Nek10 mediates G2/M cell cycle arrest and MEK autoactivation in response to UV irradiation. Mol Cell Biol (2010) 0.96
"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases. World J Biol Chem (2014) 0.91
Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum. BMC Microbiol (2010) 0.87
DYNLL/LC8 protein controls signal transduction through the Nek9/Nek6 signaling module by regulating Nek6 binding to Nek9. J Biol Chem (2011) 0.84
Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements. Histochem Cell Biol (2011) 0.83
Exploration of the cell-cycle genes found within the RIKEN FANTOM2 data set. Genome Res (2003) 0.82
Cyclophilin nomenclature problems, or, 'a visit from the sequence police'. Hum Genomics (2004) 0.81
Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression. Cell Cycle (2013) 0.78
Proteome profiling of human cutaneous leishmaniasis lesion. J Invest Dermatol (2014) 0.78
Evolutionary emergence of a novel splice variant with an opposite effect on the cell cycle. Mol Cell Biol (2015) 0.77
Structure, function, and evolution of plant NIMA-related kinases: implication for phosphorylation-dependent microtubule regulation. J Plant Res (2015) 0.77
Insights into dynamic mitotic chromatin organization through the NIMA kinase suppressor SonC, a chromatin-associated protein involved in the DNA damage response. Genetics (2013) 0.76
Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array. PLoS One (2014) 0.76
NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protection. Cell Cycle (2016) 0.75
Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents. PLoS One (2015) 0.75
New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing. Proteome Sci (2015) 0.75
Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia. Growth Horm IGF Res (2006) 1.61
Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot Cell (2007) 1.35
Identification of a lysophosphatidylserine receptor on mast cells. Biochem Biophys Res Commun (2006) 1.30
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells. Int J Mol Med (2004) 1.14
Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance. J Antimicrob Chemother (2004) 1.08
Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway. Mol Cancer Ther (2002) 1.07
Candida glabrata ATP-binding cassette transporters Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporters show phosphorylation-dependent pumping properties. J Biol Chem (2002) 1.05
BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors. Mol Cancer Ther (2004) 1.03
Ets-1-dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus through interaction with Daxx. J Biol Chem (2006) 1.03
Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain. Biochem Biophys Res Commun (2003) 1.01
Inhibition of fungal ABC transporters by unnarmicin A and unnarmicin C, novel cyclic peptides from marine bacterium. Biochem Biophys Res Commun (2007) 1.00
Candida albicans protein kinase CaHsl1p regulates cell elongation and virulence. Mol Microbiol (2005) 1.00
Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 1.00
Phosphorylation of candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability. J Biol Chem (2004) 0.99
Tandem affinity purification of the Candida albicans septin protein complex. Yeast (2004) 0.99
Novel approach to designing primers for identification and distinction of the human pathogenic fungi Coccidioides immitis and Coccidioides posadasii by PCR amplification. J Clin Microbiol (2006) 0.98
Biosynthesis of hibarimicins. I. 13C-labeling experiments. J Antibiot (Tokyo) (2002) 0.98
Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. J Biol Chem (2004) 0.97
Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2. Jpn J Cancer Res (2002) 0.97
Anti-Candida-biofilm activity of micafungin is attenuated by voriconazole but restored by pharmacological inhibition of Hsp90-related stress responses. Med Mycol (2010) 0.97
Reduction of hepatitis C virus NS5A phosphorylation through its interaction with amphiphysin II. Biochem Biophys Res Commun (2005) 0.96
Biosynthesis of hibarimicins. II. Elucidation of biosynthetic pathway by cosynthesis using blocked mutants. J Antibiot (Tokyo) (2002) 0.95
Construction of FLAG tagging vectors for Candida albicans. Yeast (2002) 0.95
Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans. Infect Immun (2006) 0.94
Highly effective recombinant format of a humanized IgG-like bispecific antibody for cancer immunotherapy with retargeting of lymphocytes to tumor cells. J Biol Chem (2007) 0.94
Biosynthesis of hibarimicins. III. Structures of new hibarimicin-related metabolites produced by blocked mutants. J Antibiot (Tokyo) (2002) 0.94
Construction of a pair of practical Nocardia-Escherichia coli shuttle vectors. Jpn J Infect Dis (2007) 0.93
Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle. Microbes Infect (2012) 0.93
Interferon regulatory factor-2 regulates cell growth through its acetylation. J Biol Chem (2003) 0.93
Bisebromoamide, a potent cytotoxic peptide from the marine cyanobacterium Lyngbya sp.: isolation, stereostructure, and biological activity. Org Lett (2009) 0.93
Cyclic AMP inhibits translation of cyclin D3 in T lymphocytes at the level of elongation by inducing eEF2-phosphorylation. Cell Signal (2003) 0.91
Trichosporon species isolated from guano samples obtained from bat-inhabited caves in Japan. Appl Environ Microbiol (2005) 0.91
Effects of hibarimicins and hibarimicin-related compounds produced by Microbispora on v-Src kinase activity and growth and differentiation of human myeloid leukemia HL-60 cells. J Antibiot (Tokyo) (2002) 0.89
Characterization of the Saccharomyces cerevisiae sec6-4 mutation and tools to create S. cerevisiae strains containing the sec6-4 allele. Gene (2005) 0.88
Tcc1p, a novel protein containing the tetratricopeptide repeat motif, interacts with Tup1p to regulate morphological transition and virulence in Candida albicans. Eukaryot Cell (2006) 0.88
A putative dual-specific protein phosphatase encoded by YVH1 controls growth, filamentation and virulence in Candida albicans. Microbiology (2005) 0.88
Identification of the putative protein phosphatase gene PTC1 as a virulence-related gene using a silkworm model of Candida albicans infection. Eukaryot Cell (2008) 0.87
Functional analysis of fungal drug efflux transporters by heterologous expression in Saccharomyces cerevisiae. Jpn J Infect Dis (2005) 0.87
Anicemycin, a new inhibitor of anchorage-independent growth of tumor cells from Streptomyces sp. TP-A0648. J Antibiot (Tokyo) (2005) 0.87
Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells. FEBS Lett (2008) 0.87
Enhancement of anchorage-independent growth of human pancreatic carcinoma MIA PaCa-2 cells by signaling from protein kinase C to mitogen-activated protein kinase. Mol Carcinog (2002) 0.86
Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea. Int J Neuropsychopharmacol (2007) 0.86
Poly(ADP-ribose) polymerase-1 inhibits ATM kinase activity in DNA damage response. Biochem Biophys Res Commun (2004) 0.83
The trend of imported mycoses in Japan. J Infect Chemother (2003) 0.83
Design of hypoxia-targeting protein tyrosine kinase inhibitor using an innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione. Biochim Biophys Acta (2004) 0.82
Cellular and biochemical mechanisms of the resistance of human cancer cells to a new anticancer ribo-nucleoside, TAS-106. Jpn J Cancer Res (2002) 0.82
Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases. Bioorg Med Chem Lett (2006) 0.82
Modification of pyrimidine derivatives from antiviral agents to antitumor agents. Anticancer Res (2006) 0.82
Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR. Antiviral Res (2009) 0.81
Serum adiponectin levels in adult growth hormone deficiency and acromegaly. Growth Horm IGF Res (2004) 0.81
Combinatory effect of fluconazole and FDA-approved drugs against Candida albicans. J Infect Chemother (2013) 0.81
TX-1123: an antitumor 2-hydroxyarylidene-4-cyclopentene-1,3-dione as a protein tyrosine kinase inhibitor having low mitochondrial toxicity. Bioorg Med Chem (2002) 0.81
Design, synthesis, and biological evaluation of aminoboronic acids as growth-factor receptor inhibitors of EGFR and VEGFR-1 tyrosine kinases. Chembiochem (2004) 0.80
Identification of LY83583 as a specific inhibitor of Candida albicans MPS1 protein kinase. Biochem Biophys Res Commun (2011) 0.79
A cell-based, microplate colorimetric screen identifies 7,8-benzoflavone and green tea gallate catechins as inhibitors of the hepatitis C virus. Biol Pharm Bull (2012) 0.79
Anicequol, a novel inhibitor for anchorage-independent growth of tumor cells from Penicillium aurantiogriseum Dierckx TP-F0213. J Antibiot (Tokyo) (2002) 0.79
p38MAPK and Rho-dependent kinase are involved in anoikis induced by anicequol or 25-hydroxycholesterol in DLD-1 colon cancer cells. Biochem Biophys Res Commun (2012) 0.78
Beta-hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases. Jpn J Cancer Res (2002) 0.77
Cytotoxic and EGFR tyrosine kinase inhibitory activities of aglycone derivatives obtained by enzymatic hydrolysis of oleoside-type secoiridoid glucosides, oleuropein and ligustroside. J Nat Med (2010) 0.76
Acid-labile subunit in growth hormone excess and deficiency in adults: evaluation of its diagnostic value in comparison with insulin-like growth factor (IGF)-I and IGF-binding protein-3. Endocr J (2002) 0.76
[ABC transporters of pathogenic fungi: recent advances in functional analyses]. Nihon Ishinkin Gakkai Zasshi (2005) 0.76
Alkyl isothiocyanates suppress epidermal growth factor receptor kinase activity but augment tyrosine kinase activity. Cancer Epidemiol (2009) 0.76
Gamma-herpesviruses and cellular signaling in AIDS-associated malignancies. Cancer Sci (2007) 0.76
New cytotoxic bisindole alkaloids with protein tyrosine kinase inhibitory activity from a myxomycete Lycogala epidendrum. Bioorg Med Chem Lett (2005) 0.76
Is Histoplasma capsulatum a native inhabitant of Japan? Microbiol Immunol (2008) 0.76
Induction of heat-shock protein 70 by prostaglandin A₁ inhibits HIV-1 Vif-mediated degradation of APOBEC3G. Antiviral Res (2013) 0.76
Design of antiangiogenic hypoxic cell radiosensitizers: 2-nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety. Bioorg Med Chem (2008) 0.75
A mammalian two-hybrid screening system for inhibitors of interaction between HIV Nef and the cellular tyrosine kinase Hck. Antiviral Res (2002) 0.75
[The 15th result of screening for antineoplastic agents]. Gan To Kagaku Ryoho (2013) 0.75
[Curative Surgery for Advanced Gastric Cancer with Extensive Lymph Node Metastasis after Long-Term Chemotherapy]. Gan To Kagaku Ryoho (2015) 0.75
The Relationship between Occurrence Timing of Dispensing Errors and Subsequent Danger to Patients under the Situation According to the Classification of Drugs by Efficacy. Yakugaku Zasshi (2016) 0.75
Benzamides and benzamidines as specific inhibitors of epidermal growth factor receptor and v-Src protein tyrosine kinases. Bioorg Med Chem (2004) 0.75
Synthesis and biological evaluation of benzamides and benzamidines: structural requirement of a pyrimidine ring for inhibition of EGFR tyrosine kinase. Bioorg Med Chem Lett (2004) 0.75
[An inflammatory pseudotumor of the liver mimicking a metastatic lesion of gallbladder cancer - a case report]. Gan To Kagaku Ryoho (2014) 0.75
[Two cases of rectal NET excised by laparoscopic surgery]. Gan To Kagaku Ryoho (2014) 0.75
[Screening of protein kinase inhibitors]. Gan To Kagaku Ryoho (2004) 0.75
[The 14th result of screening for antineoplastic agents]. Gan To Kagaku Ryoho (2013) 0.75
The resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells. Biol Pharm Bull (2010) 0.75