Published in J Biol Chem on October 28, 2004
Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal (2010) 2.04
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex. Neuron (2008) 1.94
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol Biol Cell (2005) 1.69
Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration. Proc Natl Acad Sci U S A (2005) 1.32
Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. J Am Soc Nephrol (2010) 1.22
Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. Mol Cell Biol (2007) 1.08
Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1. Mol Cell Biol (2007) 1.07
Synaptic plasticity, a symphony in GEF. ACS Chem Neurosci (2010) 1.06
Endothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt. Mol Biol Cell (2008) 1.04
EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180. Oncogene (2013) 1.00
An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration. Nat Cell Biol (2014) 0.98
α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome. Am J Pathol (2013) 0.96
Role of VASP phosphorylation for the regulation of microglia chemotaxis via the regulation of focal adhesion formation/maturation. Mol Cell Neurosci (2009) 0.94
Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619. Prostaglandins Leukot Essent Fatty Acids (2008) 0.92
Endothelin-1 induces p66Shc activation through EGF receptor transactivation: Role of beta(1)Pix/Galpha(i3) interaction. Cell Signal (2009) 0.89
Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells. Mol Biol Cell (2011) 0.89
Roles of P21-activated kinases and associated proteins in epithelial wound healing. Int Rev Cell Mol Biol (2008) 0.85
Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors. Mol Vis (2011) 0.83
The role of beta(1)Pix/caveolin-1 interaction in endothelin signaling through Galpha subunits. Biochem Biophys Res Commun (2009) 0.83
Role of βPix in the Kidney. Front Physiol (2012) 0.83
Identification of phosphorylation sites in betaPIX and PAK1. J Cell Sci (2007) 0.81
The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochem Pharmacol (2006) 0.81
The protein kinase A regulatory subunit R1A (Prkar1a) plays critical roles in peripheral nerve development. J Neurosci (2013) 0.80
Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease. Kidney Int (2016) 0.80
Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1. Cancer Res (2016) 0.79
Guanylate cyclase and cyclic GMP-dependent protein kinase regulate agrin signaling at the developing neuromuscular junction. Dev Biol (2007) 0.78
The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin. J Biol Chem (2013) 0.78
P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS One (2016) 0.77
Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome. Matrix Biol (2016) 0.76
Endothelin and the glomerulus in chronic kidney disease. Semin Nephrol (2015) 0.75
The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. J Biol Chem (2004) 2.22
The impact of robotic surgery on pelvic lymph node dissection during radical prostatectomy for localized prostate cancer: the Brown University early robotic experience. Can J Urol (2009) 1.42
Thoracic intradural extramedullary capillary hemangioma. AJNR Am J Neuroradiol (2004) 1.31
Caveolar endocytosis is critical for BK virus infection of human renal proximal tubular epithelial cells. J Virol (2007) 1.24
Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases. Expert Rev Mol Med (2011) 1.22
Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. J Am Soc Nephrol (2010) 1.22
Regulation of MDR-1 (P-glycoprotein) by cyclooxygenase-2. J Biol Chem (2002) 1.17
Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. Mol Cell Biol (2007) 1.08
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. J Am Soc Nephrol (2013) 1.04
Endothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt. Mol Biol Cell (2008) 1.04
Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth. Anticancer Res (2009) 0.98
Regulation of TGF-beta1/MAPK-mediated PAI-1 gene expression by the actin cytoskeleton in human mesangial cells. Exp Cell Res (2007) 0.96
Intracellular trafficking pathway of BK Virus in human renal proximal tubular epithelial cells. Virology (2007) 0.96
Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. J Biol Chem (2003) 0.96
Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells. J Neurochem (2004) 0.95
Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading. J Cell Physiol (2009) 0.93
Mitochondrial genomic contribution to mitochondrial dysfunction in Alzheimer's disease. J Alzheimers Dis (2006) 0.93
CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. Oncogene (2003) 0.92
Endothelin-1 induces p66Shc activation through EGF receptor transactivation: Role of beta(1)Pix/Galpha(i3) interaction. Cell Signal (2009) 0.89
Stable propagation of human embryonic and induced pluripotent stem cells on decellularized human substrates. Biotechnol Prog (2010) 0.87
BK virus (BKV): infection, propagation, quantitation, purification, labeling, and analysis of cell entry. Curr Protoc Cell Biol (2009) 0.86
Repression of BK virus infection of human renal proximal tubular epithelial cells by pravastatin. Transplantation (2008) 0.85
Cyclooxygenase 2 rescues LNCaP prostate cancer cells from sanguinarine-induced apoptosis by a mechanism involving inhibition of nitric oxide synthase activity. Cancer Res (2006) 0.85
The role of beta(1)Pix/caveolin-1 interaction in endothelin signaling through Galpha subunits. Biochem Biophys Res Commun (2009) 0.83
Role of βPix in the Kidney. Front Physiol (2012) 0.83
Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system. Biochem Biophys Res Commun (2010) 0.83
20-HETE-producing enzymes are up-regulated in human cancers. Cancer Genomics Proteomics (2012) 0.82
CrkII associates with BCAR3 in response to endothelin-1 in human glomerular mesangial cells. Exp Biol Med (Maywood) (2006) 0.82
Exome sequencing in familial corticobasal degeneration. Parkinsonism Relat Disord (2013) 0.82
Endothelin 1 stimulates beta1Pix-dependent activation of Cdc42 through the G(salpha) pathway. Exp Biol Med (Maywood) (2006) 0.81
The Rac/Cdc42 guanine nucleotide exchange factor beta1Pix enhances mastoparan-activated Gi-dependent pathway in mast cells. Biochem Biophys Res Commun (2004) 0.80
Targeting 20-HETE producing enzymes in cancer - rationale, pharmacology, and clinical potential. Onco Targets Ther (2013) 0.80
Aortic cholesterol accumulation correlates with systemic inflammation but not hepatic and gonadal adipose tissue inflammation in low-density lipoprotein receptor null mice. Nutr Res (2013) 0.80
Upregulation of fibronectin expression by COX-2 is mediated by interaction with ELMO1. Cell Signal (2010) 0.79
Cyclooxygenase-2 inhibits tumor necrosis factor alpha-mediated apoptosis in renal glomerular mesangial cells. J Biol Chem (2003) 0.78
ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells. J Cell Physiol (2007) 0.78
Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells. Brain Res (2006) 0.77
C3G overexpression in glomerular epithelial cells during anti-GBM-induced glomerulonephritis. Kidney Int (2008) 0.77
Cyclooxygenase 2 inhibits SAPK activation in neuronal apoptosis. Biochem Biophys Res Commun (2003) 0.76
Endothelin signaling via guanine exchange factor C3G in renal glomerular mesangial cells. Can J Physiol Pharmacol (2010) 0.76
Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). J Am Soc Nephrol (2006) 0.76
Complexity of IFNγ signaling gets another twist. Cell Cycle (2011) 0.75
p66Shc regulates renal vascular tone in hypertension-induced nephropathy. J Clin Invest (2016) 0.75
The impact of silver nanoparticles on the composting of municipal solid waste. Environ Sci Technol (2013) 0.75