Published in Stem Cells on January 01, 2004
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS One (2011) 2.74
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A (2007) 2.60
Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. EMBO J (2011) 2.51
Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin. Stem Cells (2006) 2.37
Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian rats. Stem Cells (2007) 2.22
Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A (2008) 1.97
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (2010) 1.74
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. Proc Natl Acad Sci U S A (2006) 1.69
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J Cell Sci (2011) 1.50
Specification of neuronal and glial subtypes from human pluripotent stem cells. Cell Mol Life Sci (2011) 1.40
Assessment of stromal-derived inducing activity in the generation of dopaminergic neurons from human embryonic stem cells. Stem Cells (2008) 1.37
Directed differentiation of mouse embryonic stem cells into thyroid follicular cells. Endocrinology (2006) 1.35
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. PLoS One (2008) 1.29
Specification of midbrain dopamine neurons from primate pluripotent stem cells. Stem Cells (2012) 1.28
Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells. Stem Cells (2005) 1.22
A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo. Brain Res (2006) 1.17
Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease. Stem Cells (2006) 1.16
A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells. PLoS One (2009) 1.11
Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits. Stem Cells (2006) 1.11
Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A (2011) 1.10
Human embryonic stem cell differentiation toward regional specific neural precursors. Stem Cells (2009) 1.10
Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix. Proc Natl Acad Sci U S A (2006) 1.05
Human embryonic stem cells for brain repair? Philos Trans R Soc Lond B Biol Sci (2008) 1.04
Achieving stable human stem cell engraftment and survival in the CNS: is the future of regenerative medicine immunodeficient? Regen Med (2011) 1.03
Human embryonic stem cells: derivation, culture, and differentiation: a review. Restor Neurol Neurosci (2010) 1.02
Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PLoS One (2012) 1.02
Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons. PLoS One (2008) 0.97
Important precautions when deriving patient-specific neural elements from pluripotent cells. Cytotherapy (2009) 0.97
An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection. Neuropsychopharmacology (2006) 0.97
Cell-based therapies for Parkinson disease—past insights and future potential. Nat Rev Neurol (2015) 0.97
Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells. Mol Brain (2008) 0.96
Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. Stem Cells Int (2012) 0.95
A large-scale proteomic analysis of human embryonic stem cells. BMC Genomics (2007) 0.95
It's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation. Neurochem Res (2012) 0.94
Effects of histocompatibility and host immune responses on the tumorigenicity of pluripotent stem cells. Semin Immunopathol (2011) 0.94
Early specification of dopaminergic phenotype during ES cell differentiation. BMC Dev Biol (2007) 0.91
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem Cells Dev (2013) 0.91
Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease. Brain Res (2006) 0.91
Autofluorescent cells in rat brain can be convincing impostors in green fluorescent reporter studies. J Neurosci Methods (2011) 0.91
Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons. PLoS One (2009) 0.90
Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra. PLoS One (2011) 0.90
Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells (2009) 0.90
Conditions for tumor-free and dopamine neuron-enriched grafts after transplanting human ES cell-derived neural precursor cells. Mol Ther (2009) 0.89
"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells. BMC Genomics (2007) 0.88
Nanofiber matrices promote the neuronal differentiation of human embryonic stem cell-derived neural precursors in vitro. Tissue Eng Part A (2010) 0.87
Cell-based therapies for Parkinson's disease: past, present, and future. Antioxid Redox Signal (2009) 0.85
The Human Model: Changing Focus on Autism Research. Biol Psychiatry (2015) 0.85
Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells. Front Neuroanat (2007) 0.84
Dopaminergic neurons derived from BG01V2, a variant of human embryonic stem cell line BG01. Restor Neurol Neurosci (2008) 0.84
Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models. Stem Cells Cloning (2013) 0.83
A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies. Front Cell Neurosci (2013) 0.81
Preclinical assessment of stem cell therapies for neurological diseases. ILAR J (2009) 0.81
Pluripotent stem cells for Parkinson's disease: progress and challenges. Stem Cell Res Ther (2013) 0.80
Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells. PLoS One (2015) 0.80
Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells. J Comp Neurol (2014) 0.80
Development of stem cell-based therapy for Parkinson's disease. Transl Neurodegener (2015) 0.80
Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells. Front Genet (2014) 0.80
Dopamine release from transplanted neural stem cells in Parkinsonian rat striatum in vivo. Proc Natl Acad Sci U S A (2014) 0.79
Directed dopaminergic neuron differentiation from human pluripotent stem cells. J Vis Exp (2014) 0.79
Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20. Front Neurosci (2008) 0.79
Human embryonic stem cells which express hrGFP in the undifferentiated state and during dopaminergic differentiation. Restor Neurol Neurosci (2009) 0.79
Stem cells in development of therapeutics for Parkinson's disease: a perspective. J Cell Biochem (2008) 0.78
Human embryonic stem cells: a potential source of transplantable neural progenitor cells. Neurosurg Focus (2008) 0.78
Human embryonic stem cell technology: large scale cell amplification and differentiation. Cytotechnology (2006) 0.77
The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale. PLoS One (2013) 0.77
Thyroid stem cells--danger or resource? Acta Otorhinolaryngol Ital (2009) 0.77
Functional differentiation of midbrain neurons from human cord blood-derived induced pluripotent stem cells. Stem Cell Res Ther (2014) 0.77
Constraining the Pluripotent Fate of Human Embryonic Stem Cells for Tissue Engineering and Cell Therapy - The Turning Point of Cell-Based Regenerative Medicine. Br Biotechnol J (2013) 0.77
Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. PLoS One (2013) 0.76
Potential sources of stem cells as a regenerative therapy for Parkinson's disease. Stem Cells Cloning (2010) 0.76
Can pluripotent stem cells be used in cell-based therapy? Cell Reprogram (2014) 0.76
A new technique for modeling neuronal connectivity using human pluripotent stem cells. Restor Neurol Neurosci (2015) 0.76
Immortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neurons. J Cell Mol Med (2012) 0.76
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS One (2012) 0.76
The Production and Characteristics of a Mouse's Embryonic Stem Cell Lineage, Transfected by the Glia Neurotrophic Factor and Gene Fused with the Green Fluorescent Protein Gene. Acta Naturae (2009) 0.75
Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy. Stem Cells Int (2016) 0.75
PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes. PLoS One (2016) 0.75
Function of mouse embryonic stem cell-derived supporting cells in neural progenitor cell maturation and long term expansion. PLoS One (2013) 0.75
[Stem cells--cloning, plasticity, bioethic]. Wien Med Wochenschr (2008) 0.75
A Compendium of Preparation and Application of Stem Cells in Parkinson's Disease: Current Status and Future Prospects. Front Aging Neurosci (2016) 0.75
Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther (2014) 0.75
Interneurons of the neocortical inhibitory system. Nat Rev Neurosci (2004) 13.33
Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex. Nat Rev Neurosci (2008) 8.14
Analysis of microarray data using Z score transformation. J Mol Diagn (2003) 6.82
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med (2006) 6.04
An administrative claims measure suitable for profiling hospital performance on the basis of 30-day all-cause readmission rates among patients with heart failure. Circ Cardiovasc Qual Outcomes (2008) 6.00
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med (2015) 5.71
Patterns of hospital performance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ Cardiovasc Qual Outcomes (2009) 5.66
An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with an acute myocardial infarction. Circulation (2006) 5.35
National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008. JAMA (2011) 5.16
Regulatory networks define phenotypic classes of human stem cell lines. Nature (2008) 4.98
A cis-regulatory map of the Drosophila genome. Nature (2011) 4.80
An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with heart failure. Circulation (2006) 4.52
RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature (2002) 4.37
Trends in length of stay and short-term outcomes among Medicare patients hospitalized for heart failure, 1993-2006. JAMA (2010) 4.36
Reduction in acute myocardial infarction mortality in the United States: risk-standardized mortality rates from 1995-2006. JAMA (2009) 4.24
Association between maintenance of certification examination scores and quality of care for medicare beneficiaries. Arch Intern Med (2008) 4.20
The melting Himalayas: cascading effects of climate change on water, biodiversity, and livelihoods. Conserv Biol (2009) 4.02
Recent national trends in readmission rates after heart failure hospitalization. Circ Heart Fail (2009) 3.95
Effect of air pollution control on life expectancy in the United States: an analysis of 545 U.S. counties for the period from 2000 to 2007. Epidemiology (2013) 3.93
Genomic alterations in cultured human embryonic stem cells. Nat Genet (2005) 3.89
Gene expression in human embryonic stem cell lines: unique molecular signature. Blood (2003) 3.73
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science (2011) 3.66
Recent declines in hospitalizations for acute myocardial infarction for Medicare fee-for-service beneficiaries: progress and continuing challenges. Circulation (2010) 3.32
Differences between human and mouse embryonic stem cells. Dev Biol (2004) 3.30
Synaptic connections and small circuits involving excitatory and inhibitory neurons in layers 2-5 of adult rat and cat neocortex: triple intracellular recordings and biocytin labelling in vitro. Cereb Cortex (2002) 3.28
Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells (2005) 3.16
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood (2007) 3.05
RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell (2011) 2.90
Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. J Neurosci (2005) 2.76
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells (2005) 2.74
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci (2008) 2.67
New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Causes of blindness and visual impairment in urban and rural areas in Beijing: the Beijing Eye Study. Ophthalmology (2006) 2.59
Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environ Health Perspect (2011) 2.56
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem (2002) 2.45
High myopia and glaucoma susceptibility the Beijing Eye Study. Ophthalmology (2006) 2.40
National patterns of risk-standardized mortality and readmission for acute myocardial infarction and heart failure. Update on publicly reported outcomes measures based on the 2010 release. Circ Cardiovasc Qual Outcomes (2010) 2.33
Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation. Stem Cells Dev (2014) 2.27
An administrative claims model for profiling hospital 30-day mortality rates for pneumonia patients. PLoS One (2011) 2.22
Hospital volume and 30-day mortality for three common medical conditions. N Engl J Med (2010) 2.20
Outcomes of deep anterior lamellar keratoplasty using the big-bubble technique in various corneal diseases. Am J Ophthalmol (2012) 2.20
The performance of US hospitals as reflected in risk-standardized 30-day mortality and readmission rates for medicare beneficiaries with pneumonia. J Hosp Med (2010) 2.20
Effectiveness and acceptability of a computerized decision support system using modified Wells criteria for evaluation of suspected pulmonary embolism. Ann Emerg Med (2010) 2.19
MPSS profiling of human embryonic stem cells. BMC Dev Biol (2004) 2.17
Association of retail tobacco marketing with adolescent smoking. Am J Public Health (2004) 2.15
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proc Natl Acad Sci U S A (2009) 2.15
National trends in outcomes among elderly patients with heart failure. Am J Med (2006) 2.13
Regional variation in the treatment and outcomes of myocardial infarction: investigating New England's advantage. Am Heart J (2003) 2.11
Relationship between hospital readmission and mortality rates for patients hospitalized with acute myocardial infarction, heart failure, or pneumonia. JAMA (2013) 2.06
Hospital-acquired pressure ulcers: results from the national Medicare Patient Safety Monitoring System study. J Am Geriatr Soc (2012) 2.03
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron (2009) 2.01
Long-term culture of human embryonic stem cells in feeder-free conditions. Dev Dyn (2004) 2.01
An Arabidopsis glutathione peroxidase functions as both a redox transducer and a scavenger in abscisic acid and drought stress responses. Plant Cell (2006) 2.01
Systematic review and meta-analysis of Meniett therapy for Meniere's disease. Laryngoscope (2014) 1.98
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy (2010) 1.97
"America's Best Hospitals" in the treatment of acute myocardial infarction. Arch Intern Med (2007) 1.96
Fatty acid regulation of hepatic gene transcription. J Nutr (2005) 1.96
Children's food consumption during television viewing. Am J Clin Nutr (2004) 1.95
Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex. Proc Natl Acad Sci U S A (2007) 1.92
Comparison of hospital risk-standardized mortality rates calculated by using in-hospital and 30-day models: an observational study with implications for hospital profiling. Ann Intern Med (2012) 1.90
Stress-induced relapse to cocaine seeking: roles for the CRF(2) receptor and CRF-binding protein in the ventral tegmental area of the rat. Psychopharmacology (Berl) (2007) 1.86
Inosine reduces ischemic brain injury in rats. Stroke (2005) 1.83
Coronary heart disease mortality for six ethnic groups in California, 1990-2000. Ann Epidemiol (2004) 1.83
Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression. Hepatology (2015) 1.81
Developmental switch in the contribution of presynaptic and postsynaptic NMDA receptors to long-term depression. J Neurosci (2007) 1.81
Rates of acute care admissions for frail older people living with met versus unmet activity of daily living needs. J Am Geriatr Soc (2006) 1.79
Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology (2008) 1.79
Stroke patient outcomes in US hospitals before the start of the Joint Commission Primary Stroke Center certification program. Stroke (2009) 1.78
Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophr Res (2002) 1.76
Properties of a fetal multipotent neural stem cell (NEP cell). Dev Biol (2002) 1.75
Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001. Stem Cells Dev (2004) 1.75
Predictors of the incident metabolic syndrome in adults: the Insulin Resistance Atherosclerosis Study. Diabetes Care (2004) 1.74
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J (2007) 1.74
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (2010) 1.74
Membrane properties of rat embryonic multipotent neural stem cells. J Neurochem (2004) 1.73
Risk and predictors of stroke after myocardial infarction among the elderly: results from the Cooperative Cardiovascular Project. Circulation (2002) 1.71
PDZ domains of Par-3 as potential phosphoinositide signaling integrators. Mol Cell (2007) 1.70
MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biochem J (2011) 1.67
Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro. Virology (2007) 1.66
CD44 expression identifies astrocyte-restricted precursor cells. Dev Biol (2004) 1.66
Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex. Cereb Cortex (2006) 1.64
The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders. Neuropsychopharmacology (2006) 1.64
Retinol binding protein 4 stimulates hepatic sterol regulatory element-binding protein 1 and increases lipogenesis through the peroxisome proliferator-activated receptor-γ coactivator 1β-dependent pathway. Hepatology (2013) 1.63