Published in Dev Biol on May 15, 2004
Germline competent embryonic stem cells derived from rat blastocysts. Cell (2008) 5.52
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
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Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circ Heart Fail (2009) 2.72
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Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2. PLoS Genet (2008) 2.01
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Human embryonic stem cell transplantation to repair the infarcted myocardium. Heart (2007) 1.86
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Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol Prog (2009) 1.61
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A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (2009) 1.59
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Transcriptional analysis of early lineage commitment in human embryonic stem cells. BMC Dev Biol (2007) 1.31
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Immunological applications of stem cells in type 1 diabetes. Endocr Rev (2011) 1.20
Expression profiling of nuclear receptors in human and mouse embryonic stem cells. Mol Endocrinol (2009) 1.16
LongSAGE profiling of nine human embryonic stem cell lines. Genome Biol (2007) 1.15
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Functional genomics of 5- to 8-cell stage human embryos by blastomere single-cell cDNA analysis. PLoS One (2010) 1.10
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Functional cardiac tissue engineering. Regen Med (2012) 1.07
The multiparametric effects of hydrodynamic environments on stem cell culture. Tissue Eng Part B Rev (2011) 1.06
Nuclear receptor regulation of stemness and stem cell differentiation. Exp Mol Med (2009) 1.03
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Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cells. J Biol Chem (2010) 1.01
Keeping an eye on retinoblastoma control of human embryonic stem cells. J Cell Biochem (2009) 1.01
Safely targeting cancer stem cells via selective catenin coactivator antagonism. Cancer Sci (2014) 1.00
Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver. Histochem Cell Biol (2005) 0.99
The RB family is required for the self-renewal and survival of human embryonic stem cells. Nat Commun (2012) 0.99
Meta-analysis of differentiating mouse embryonic stem cell gene expression kinetics reveals early change of a small gene set. PLoS Comput Biol (2006) 0.98
Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells. Genomics (2006) 0.98
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells. Elife (2012) 0.97
FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans. EMBO J (2011) 0.97
A UTF1-based selection system for stable homogeneously pluripotent human embryonic stem cell cultures. Nucleic Acids Res (2007) 0.96
Modeling co-expression across species for complex traits: insights to the difference of human and mouse embryonic stem cells. PLoS Comput Biol (2010) 0.96
Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain. Development (2011) 0.96
Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal. Stem Cells Dev (2010) 0.96
Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells. Exp Mol Med (2014) 0.96
Paracrine and epigenetic control of trophectoderm differentiation from human embryonic stem cells: the role of bone morphogenic protein 4 and histone deacetylases. Stem Cells Dev (2011) 0.96
Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes. Circ Res (2015) 0.96
A large-scale proteomic analysis of human embryonic stem cells. BMC Genomics (2007) 0.95
Modeling Huntington's disease with induced pluripotent stem cells. Mol Cell Neurosci (2013) 0.94
Expression profiling of human glial precursors. BMC Dev Biol (2008) 0.94
Pluripotent stem cells for the study of CNS development. Front Mol Neurosci (2011) 0.92
Functional ion channels in stem cells. World J Stem Cells (2011) 0.91
Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells. Mol Hum Reprod (2008) 0.91
Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease. Brain Res (2006) 0.91
Identification and characterization of side population cells in embryonic stem cell cultures. Stem Cells Dev (2009) 0.90
Alkaline phosphatase in stem cells. Stem Cells Int (2015) 0.90
Potentiality of embryonic stem cells: an ethical problem even with alternative stem cell sources. J Med Ethics (2006) 0.88
A comparative anatomic and physiologic overview of the porcine heart. J Am Assoc Lab Anim Sci (2014) 0.88
Induced pluripotent stem cells and the stability of the differentiated state. EMBO Rep (2009) 0.87
Regulation of embryonic stem cell pluripotency by heat shock protein 90. Stem Cells (2012) 0.87
Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk. Environ Health Perspect (2009) 0.86
Small molecules and stem cells. Potency and lineage commitment: the new quest for the fountain of youth. J Med Chem (2010) 0.86
Cardiac regeneration using pluripotent stem cells--progression to large animal models. Stem Cell Res (2014) 0.86
Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment. Cytometry A (2009) 0.85
A novel method for cross-species gene expression analysis. BMC Bioinformatics (2013) 0.85
Asynchronous replication and autosome-pair non-equivalence in human embryonic stem cells. PLoS One (2009) 0.85
Potential for pharmacological manipulation of human embryonic stem cells. Br J Pharmacol (2013) 0.85
Vascular potential of human pluripotent stem cells. Arterioscler Thromb Vasc Biol (2010) 0.85
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells. Reprod Biol Endocrinol (2006) 0.84
Genome resource banking of biomedically important laboratory animals. Theriogenology (2012) 0.83
The Dynamics of Global Chromatin Remodeling are Pivotal for Tracking the Normal Pluripotency of Human Embryonic Stem Cells. Anat Physiol (2012) 0.83
Production of human pluripotent stem cell therapeutics under defined xeno-free conditions: progress and challenges. Stem Cell Rev (2015) 0.83
Differentiation of nonhuman primate embryonic stem cells along neural lineages. Differentiation (2008) 0.83
Altered characteristics of cancer stem/initiating cells in a breast cancer cell line treated with persistent 5-FU chemotherapy. Exp Ther Med (2011) 0.83
Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response. Eur Biophys J (2012) 0.82
The effect of estrogen compounds on human embryoid bodies. Reprod Sci (2012) 0.81
The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells. PLoS One (2013) 0.81
Evaluation of in vitro cytotoxicity and paracellular permeability of intact monolayers with mouse embryonic stem cells. Toxicol In Vitro (2008) 0.81
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells Dev (2012) 0.81
State of the art in stem cell research: human embryonic stem cells, induced pluripotent stem cells, and transdifferentiation. J Blood Transfus (2012) 0.80
Novel insights into embryonic stem cell self-renewal revealed through comparative human and mouse systems biology networks. Stem Cells (2014) 0.80
Stimulation of cultured h9 human embryonic stem cells with thyroid stimulating hormone does not lead to formation of thyroid-like cells. Stem Cells Int (2012) 0.79
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol (2006) 10.95
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol (2008) 10.60
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Regulatory networks define phenotypic classes of human stem cell lines. Nature (2008) 4.98
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol (2004) 4.50
Gene expression in human embryonic stem cell lines: unique molecular signature. Blood (2003) 3.73
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res (2002) 3.69
Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 3.66
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol (2010) 3.21
Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells (2005) 3.16
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood (2007) 3.05
Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells. Nat Biotechnol (2010) 2.97
Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc Natl Acad Sci U S A (2003) 2.86
High-efficiency RNA interference in human embryonic stem cells. Stem Cells (2005) 2.76
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells (2005) 2.74
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci (2008) 2.67
Characterization and culture of human embryonic stem cells. Nat Biotechnol (2005) 2.67
Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation. Glia (2005) 2.60
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 2.53
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem (2002) 2.45
LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem Cells (2004) 2.37
Dopaminergic differentiation of human embryonic stem cells. Stem Cells (2004) 2.30
Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation. Stem Cells Dev (2014) 2.27
Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord. Nat Biotechnol (2004) 2.26
MPSS profiling of human embryonic stem cells. BMC Dev Biol (2004) 2.17
Multipotent vasculogenic pericytes from human pluripotent stem cells promote recovery of murine ischemic limb. Circulation (2011) 2.16
Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium. Stem Cells (2005) 2.09
Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. Nat Biotechnol (2011) 2.08
Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction. Stem Cells (2005) 2.06
Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes. Am J Physiol Heart Circ Physiol (2003) 2.05
Human embryonic and induced pluripotent stem cell-derived cardiomyocytes exhibit beat rate variability and power-law behavior. Circulation (2012) 2.02
Long-term culture of human embryonic stem cells in feeder-free conditions. Dev Dyn (2004) 2.01
A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med (2009) 1.96
High-resolution electrophysiological assessment of human embryonic stem cell-derived cardiomyocytes: a novel in vitro model for the study of conduction. Circ Res (2002) 1.91
High-dosage ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A: results of a randomized, double-masked, controlled trial. JAMA Neurol (2013) 1.90
Differentiation of human embryonic stem cells into insulin-producing clusters. Stem Cells (2004) 1.88
Controlled, scalable embryonic stem cell differentiation culture. Stem Cells (2004) 1.87
Human embryonic stem cell transplantation to repair the infarcted myocardium. Heart (2007) 1.86
X-inactivation status varies in human embryonic stem cell lines. Stem Cells (2005) 1.84
Properties of a fetal multipotent neural stem cell (NEP cell). Dev Biol (2002) 1.75
Selective ablation of human embryonic stem cells expressing a "suicide" gene. Stem Cells (2003) 1.75
Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001. Stem Cells Dev (2004) 1.75
Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth. Stem Cells (2004) 1.74
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (2010) 1.74
Membrane properties of rat embryonic multipotent neural stem cells. J Neurochem (2004) 1.73
The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials (2007) 1.72
Recovery from paralysis in adult rats using embryonic stem cells. Ann Neurol (2006) 1.69
CD44 expression identifies astrocyte-restricted precursor cells. Dev Biol (2004) 1.66
HIV-associated sensory neuropathies. AIDS (2002) 1.65
Neuroimmunophilin ligands protect cavernous nerves after crush injury in the rat: new experimental paradigms. Eur Urol (2006) 1.63
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research. Stem Cells (2007) 1.62
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies. BMC Dev Biol (2005) 1.61
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.60
Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev Dyn (2004) 1.60
X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected. J Cell Physiol (2008) 1.59
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (2009) 1.59
Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem Cells (2005) 1.58
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines. BMC Dev Biol (2006) 1.58
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. PLoS Biol (2009) 1.57
Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation. J Cell Mol Med (2012) 1.55
Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo. Mol Cell Neurosci (2006) 1.53
Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol (2003) 1.53
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS. J Comp Neurol (2007) 1.51
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells. BMC Dev Biol (2008) 1.49
Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: protease inhibitor-mediated neurotoxicity. Ann Neurol (2006) 1.49
Generation of hepatocyte-like cells from human embryonic stem cells. Cell Transplant (2003) 1.49
Developing safe therapies from human pluripotent stem cells. Nat Biotechnol (2009) 1.48
Toward cell replacement therapy: promises and caveats. Exp Neurol (2003) 1.47
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking. J Neurosci (2008) 1.45
Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells. J Cell Mol Med (2011) 1.43