Published in Stem Cells on January 01, 2004
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A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell (2008) 5.90
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Derivation of oocytes from mouse embryonic stem cells. Science (2003) 4.03
Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev (2002) 3.52
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming. Cell (2010) 3.08
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev (2003) 2.99
Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell (2009) 2.78
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell (2010) 2.73
Combinatorial control of gene expression. Nat Struct Mol Biol (2004) 2.66
Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A (2006) 2.65
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Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell (2010) 2.58
Oct4 is required for primordial germ cell survival. EMBO Rep (2004) 2.56
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Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell (2009) 2.26
Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol (2003) 2.24
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell (2013) 2.22
Stem cell pluripotency and transcription factor Oct4. Cell Res (2002) 1.99
A central role for TFIID in the pluripotent transcription circuitry. Nature (2013) 1.82
Human adult germline stem cells in question. Nature (2010) 1.74
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Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation. J Biol Chem (2007) 1.65
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Direct reprogramming of fibroblasts into epiblast stem cells. Nat Cell Biol (2010) 1.52
Absence of OCT4 expression in somatic tumor cell lines. Stem Cells (2007) 1.41
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Pluripotential reprogramming of the somatic genome in hybrid cells occurs with the first cell cycle. Stem Cells (2007) 1.37
Progeny from sperm obtained after ectopic grafting of neonatal mouse testes. Biol Reprod (2003) 1.31
A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture. Gene (2002) 1.28
Distinct developmental ground states of epiblast stem cell lines determine different pluripotency features. Stem Cells (2011) 1.21
Variable reprogramming of the pluripotent stem cell marker Oct4 in mouse clones: distinct developmental potentials in different culture environments. Stem Cells (2005) 1.21
Nanog: a new recruit to the embryonic stem cell orchestra. Cell (2003) 1.20
Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1. Cell Res (2011) 1.20
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS One (2013) 1.18
The caudal-related protein cdx2 promotes trophoblast differentiation of mouse embryonic stem cells. Stem Cells (2005) 1.17
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Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions. PLoS One (2012) 1.15
Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation. J Biol Chem (2004) 1.14
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. Nat Commun (2013) 1.12
Parthenogenetic stem cells for tissue-engineered heart repair. J Clin Invest (2013) 1.11
Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation. Development (2010) 1.10
Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2. Development (2010) 1.10
p53 connects tumorigenesis and reprogramming to pluripotency. J Exp Med (2010) 1.09
A unique Oct4 interface is crucial for reprogramming to pluripotency. Nat Cell Biol (2013) 1.08
Generation of induced pluripotent stem cells from neural stem cells. Nat Protoc (2009) 1.07
Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke. Stroke (2011) 1.07
Differential activity by DNA-induced quarternary structures of POU transcription factors. Biochem Pharmacol (2002) 1.07
Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. J Biol Chem (2010) 1.06
Induction of pluripotency in human cord blood unrestricted somatic stem cells. Exp Hematol (2010) 1.06
Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells. Nat Protoc (2010) 1.06
Induced pluripotent stem cells at nanoscale. Stem Cells Dev (2010) 1.05
Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells. Cytometry A (2011) 1.05
Epigenetic hierarchy governing Nestin expression. Stem Cells (2009) 1.05
Establishment of totipotency does not depend on Oct4A. Nat Cell Biol (2013) 1.05
Sonic hedgehog shedding results in functional activation of the solubilized protein. Dev Cell (2011) 1.02
Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells. PLoS Biol (2011) 1.02
Induction of pluripotency: from mouse to human. Cell (2007) 1.01
Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation. Cell Transplant (2008) 1.01
Regulatory circuits underlying pluripotency and reprogramming. Trends Pharmacol Sci (2009) 1.01
MicroRNA-221 regulates FAS-induced fulminant liver failure. Hepatology (2011) 1.01
Zfp296 is a novel, pluripotent-specific reprogramming factor. PLoS One (2012) 1.00
Pluripotency deficit in clones overcome by clone-clone aggregation: epigenetic complementation? EMBO J (2003) 0.99
TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Reports (2013) 0.98
Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle. Nat Commun (2012) 0.98
Oct4-enhanced green fluorescent protein transgenic pigs: a new large animal model for reprogramming studies. Stem Cells Dev (2011) 0.97
Neural induction intermediates exhibit distinct roles of Fgf signaling. Stem Cells (2010) 0.97
Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nat Commun (2012) 0.97
Enhanced reprogramming of Xist by induced upregulation of Tsix and Dnmt3a. Stem Cells (2008) 0.97
Identification of genes specific to mouse primordial germ cells through dynamic global gene expression. Hum Mol Genet (2010) 0.96
Differentiation efficiency of induced pluripotent stem cells depends on the number of reprogramming factors. Stem Cells (2012) 0.96
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Concise review: challenging the pluripotency of human testis-derived ESC-like cells. Stem Cells (2011) 0.94
Inhibition of TGFβ signaling promotes ground state pluripotency. Stem Cell Rev (2014) 0.94
Embryonic stem cells as a potential source of gametes. Semin Reprod Med (2006) 0.93
Reprogramming somatic gene activity by fusion with pluripotent cells. Stem Cell Rev (2006) 0.92
Activity of the germline-specific Oct4-GFP transgene in normal and clone mouse embryos. Methods Mol Biol (2004) 0.91
OBF1 enhances transcriptional potential of Oct1. EMBO J (2003) 0.91
Topographic effect on human induced pluripotent stem cells differentiation towards neuronal lineage. Biomaterials (2013) 0.91
Brief report: evaluating the potential of putative pluripotent cells derived from human testis. Stem Cells (2011) 0.90
Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell (2012) 0.89
Spermatogonia: origin, physiology and prospects for conservation and manipulation of the male germ line. Reprod Fertil Dev (2006) 0.89
Reprogramming and the mammalian germline: the Weismann barrier revisited. Curr Opin Cell Biol (2012) 0.89
Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs. Cell Stem Cell (2016) 0.89
Discovery of neuritogenic compound classes inspired by natural products. Angew Chem Int Ed Engl (2013) 0.88
Erasure of cellular memory by fusion with pluripotent cells. Stem Cells (2007) 0.88
Autologous pluripotent stem cells generated from adult mouse testicular biopsy. Stem Cell Rev (2012) 0.87
Generation of parthenogenetic induced pluripotent stem cells from parthenogenetic neural stem cells. Stem Cells (2009) 0.86
Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs. Genome Res (2013) 0.86
Directing reprogramming to pluripotency by transcription factors. Curr Opin Genet Dev (2012) 0.86
Nuclear distribution of Oct-4 transcription factor in transcriptionally active and inactive mouse oocytes and its relation to RNA polymerase II and splicing factors. J Cell Biochem (2003) 0.86
Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease. J Neurochem (2011) 0.84
Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: reprogramming potential. Reprod Fertil Dev (2005) 0.84
Generating oocytes and sperm from embryonic stem cells. Semin Reprod Med (2005) 0.84
Induced pluripotent stem cells. Methods Enzymol (2010) 0.83