Published in J Clin Invest on February 22, 2013
Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model. Circ Res (2015) 1.21
Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J (2013) 1.15
Induced pluripotent stem cells for post-myocardial infarction repair: remarkable opportunities and challenges. Circ Res (2014) 1.09
Patching the heart: cardiac repair from within and outside. Circ Res (2013) 1.04
The angiogenic properties of mesenchymal stem/stromal cells and their therapeutic potential. Br Med Bull (2013) 1.04
Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther (2014) 0.95
Materials science and tissue engineering: repairing the heart. Mayo Clin Proc (2013) 0.87
Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features. Stem Cells Transl Med (2014) 0.84
The potential and challenges of using stem cells for cardiovascular repair and regeneration. Genes Dis (2014) 0.83
Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines. Circ Cardiovasc Genet (2013) 0.83
Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair. Stem Cell Res Ther (2013) 0.83
Pluripotent stem cell derived cardiomyocytes for cardiac repair. Curr Treat Options Cardiovasc Med (2014) 0.82
Bioreactor for modulation of cardiac microtissue phenotype by combined static stretch and electrical stimulation. Biofabrication (2014) 0.82
Concise review: Engineering myocardial tissue: the convergence of stem cells biology and tissue engineering technology. Stem Cells (2013) 0.81
Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation. Stem Cells (2014) 0.81
Directing parthenogenetic stem cells differentiate into adipocytes for engineering injectable adipose tissue. Stem Cells Int (2014) 0.80
Cardiac tissue engineering and regeneration using cell-based therapy. Stem Cells Cloning (2015) 0.78
Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS One (2014) 0.77
Translational aspects of cardiac cell therapy. J Cell Mol Med (2015) 0.77
Cardiac engraftment of genetically-selected parthenogenetic stem cell-derived cardiomyocytes. PLoS One (2015) 0.76
Parthenogenesis and Human Assisted Reproduction. Stem Cells Int (2015) 0.76
Striated muscle function, regeneration, and repair. Cell Mol Life Sci (2016) 0.76
Translating Myocardial Remuscularization. Circ Res (2017) 0.75
Micron-scale voltage and [Ca(2+)]i imaging in the intact heart. Front Physiol (2014) 0.75
Preclinical study of mouse pluripotent parthenogenetic embryonic stem cell derivatives for the construction of tissue-engineered skin equivalent. Stem Cell Res Ther (2016) 0.75
Virgin birth: engineered heart muscle from parthenogenetic stem cells. J Clin Invest (2013) 0.75
Computational Detection of Stage-Specific Transcription Factor Clusters during Heart Development. Front Genet (2016) 0.75
Myocardial Tissue Engineering for Regenerative Applications. Curr Cardiol Rep (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A (1993) 20.33
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell (2010) 15.58
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature (2012) 7.80
Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet (2012) 7.70
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell (2011) 6.71
Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest (2001) 6.59
Heart regeneration. Nature (2011) 5.91
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med (2006) 4.74
Tissue engineering of a differentiated cardiac muscle construct. Circ Res (2002) 4.50
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol (2004) 4.50
Pluripotency of spermatogonial stem cells from adult mouse testis. Nature (2006) 4.29
Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature (1984) 4.22
Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J Clin Invest (1996) 3.87
Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching. Lancet (2005) 3.73
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell (2012) 3.66
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature (2012) 3.63
Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res (2002) 3.52
Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation (2008) 3.11
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. Differentiation (1991) 2.97
Cardiomyocyte differentiation of human induced pluripotent stem cells. Circulation (2009) 2.86
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nat Biotechnol (2011) 2.84
Patient-specific stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells (2007) 2.58
Parthenogenetic stem cells in nonhuman primates. Science (2002) 2.54
Parthenogenic origin of benign ovarian teratomas. N Engl J Med (1975) 2.53
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nat Methods (2011) 2.29
Physiological coupling of donor and host cardiomyocytes after cellular transplantation. Circ Res (2003) 2.14
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell (2007) 2.14
Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res (2007) 1.83
Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains. Dev Biol (2007) 1.61
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res (2007) 1.58
A functional analysis of imprinting in parthenogenetic embryonic stem cells. Development (1994) 1.41
Unisexual reproduction among vertebrates. Trends Genet (2011) 1.41
Histocompatible embryonic stem cells by parthenogenesis. Science (2006) 1.36
Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells. Circ Res (2007) 1.32
X-chromosome instability in pluripotential stem cell lines derived from parthenogenetic embryos. J Embryol Exp Morphol (1983) 1.30
Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci U S A (2003) 1.19
Human leukocyte antigen matching estimations in a hypothetical bank of human embryonic stem cell lines in the Japanese population for use in cell transplantation therapy. Stem Cells (2006) 1.16
Birth of parthenote mice directly from parthenogenetic embryonic stem cells. Stem Cells (2009) 1.13
Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts. Eur Heart J (2012) 1.10
Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cell Mol Life Sci (2009) 1.00
Methylation status of imprinting centers for H19/IGF2 and SNURF/SNRPN in primate embryonic stem cells. Stem Cells (2006) 0.99
Parthenotes as a source of embryonic stem cells. Cell Prolif (2008) 0.94
Abnormal development of embryonic and extraembryonic cell lineages in parthenogenetic mouse embryos. Dev Dyn (1994) 0.94
Temporal and spatial selection against parthenogenetic cells during development of fetal chimeras. Development (1990) 0.91
Generation of parthenogenetic induced pluripotent stem cells from parthenogenetic neural stem cells. Stem Cells (2009) 0.86
Embryonic and embryonic-like stem cells in heart muscle engineering. J Mol Cell Cardiol (2010) 0.85
Systematic non-uniform distribution of parthenogenetic cells in adult mouse chimaeras. Development (1989) 0.85
Cardiac differentiation of human embryonic stem cells and their assembly into engineered heart muscle. Curr Protoc Cell Biol (2012) 0.84
Synthetic matrices to serve as niches for muscle cell transplantation. Cells Tissues Organs (2011) 0.79
Defective chorioallantoic fusion in mid-gestation lethality of parthenogenone<-->tetraploid chimeras. Dev Biol (1996) 0.79
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med (2008) 13.02
Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell (2009) 11.65
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell (2008) 10.34
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature (2008) 10.27
Oncogene-induced senescence as an initial barrier in lymphoma development. Nature (2005) 9.16
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature (2004) 8.87
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell (2008) 7.79
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature (2008) 7.07
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell (2011) 6.71
Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol (2005) 6.71
Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin Cancer Res (2007) 6.59
Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. J Am Coll Cardiol (2005) 5.99
A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell (2008) 5.90
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nat Med (2010) 4.76
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med (2006) 4.74
Development of definitive endoderm from embryonic stem cells in culture. Development (2004) 4.61
Regulatory networks in embryo-derived pluripotent stem cells. Nat Rev Mol Cell Biol (2005) 4.52
Direct reprogramming of human neural stem cells by OCT4. Nature (2009) 4.32
Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell (2012) 4.28
Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature (2004) 4.20
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia. J Clin Invest (2006) 4.06
Derivation of oocytes from mouse embryonic stem cells. Science (2003) 4.03
Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood (2007) 3.71
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell (2012) 3.66
Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development (2003) 3.60
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science (2005) 3.58
Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev (2002) 3.52
Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: a comparative study using intravascular ultrasound. J Am Coll Cardiol (2006) 3.36
TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome. Blood (2011) 3.32
Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1. Circ Res (2004) 3.30
What is the role of beta-adrenergic signaling in heart failure? Circ Res (2003) 3.22
Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia. J Clin Oncol (2011) 3.17
Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferon-α in newly diagnosed chronic myeloid leukemia. J Clin Oncol (2011) 3.09
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming. Cell (2010) 3.08
BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol (2006) 3.02
Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast. Mol Cell (2008) 3.01
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev (2003) 2.99
Cardiomyocyte cell cycle regulation. Circ Res (2002) 2.99
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation (2002) 2.98
Diagnostic accuracy of dual-source multi-slice CT-coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease. Eur Heart J (2007) 2.96
Cardiac regeneration: repopulating the heart. Annu Rev Physiol (2006) 2.92
Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice. Circ Res (2004) 2.92
Transcriptional profiling identifies Id2 function in dendritic cell development. Nat Immunol (2003) 2.91
TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression. J Clin Oncol (2011) 2.88
High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood (2006) 2.87
SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nat Biotechnol (2011) 2.84
Dimorphic effects of Notch signaling in bone homeostasis. Nat Med (2008) 2.82
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (2011) 2.82
A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell (2012) 2.81
Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell (2009) 2.78
Identification and targeting of the ROSA26 locus in human embryonic stem cells. Nat Biotechnol (2007) 2.75
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell (2010) 2.73
Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood (2012) 2.69
Combinatorial control of gene expression. Nat Struct Mol Biol (2004) 2.66
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial. Clin Cancer Res (2010) 2.66
Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A (2006) 2.65
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
The self and social cognition: the role of cortical midline structures and mirror neurons. Trends Cogn Sci (2007) 2.59
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell (2010) 2.58
Oct4 is required for primordial germ cell survival. EMBO Rep (2004) 2.56
Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans. J Clin Invest (2008) 2.54
Cardiomyogenic potential of C-kit(+)-expressing cells derived from neonatal and adult mouse hearts. Circulation (2010) 2.52
Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. J Am Coll Cardiol (2004) 2.52
Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50
Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol (2014) 2.40
Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Circ Res (2010) 2.38
Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor. J Clin Oncol (2010) 2.38
A noncytotoxic DsRed variant for whole-cell labeling. Nat Methods (2008) 2.34
Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 2.33
Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin Cancer Res (2005) 2.31
Unmasking of brugada syndrome by lithium. Circulation (2005) 2.30
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. J Clin Invest (2010) 2.29
Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (2009) 2.29
Optimizing engineered heart tissue for therapeutic applications as surrogate heart muscle. Circulation (2006) 2.26
Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell (2009) 2.26
Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes. J Clin Oncol (2011) 2.26
Complications of non-compaction of the left ventricular myocardium in a paediatric population: a prospective study. Eur Heart J (2006) 2.25
Cell-based cardiac repair: reflections at the 10-year point. Circulation (2005) 2.25
Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol (2003) 2.24
Single nucleotide polymorphism in the mutational hotspot of WT1 predicts a favorable outcome in patients with cytogenetically normal acute myeloid leukemia. J Clin Oncol (2009) 2.23
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat Biotechnol (2011) 2.22
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell (2013) 2.22
Differential cardiac remodeling in preload versus afterload. Circulation (2010) 2.20
Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice. Circ Res (2007) 2.18