Published in Development on April 01, 2010
The cellular basis for animal regeneration. Dev Cell (2011) 2.14
JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling. PLoS Genet (2014) 1.51
Stem cell systems and regeneration in planaria. Dev Genes Evol (2012) 1.51
Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach. Genome Biol (2012) 1.31
Constitutive gene expression and the specification of tissue identity in adult planarian biology. Trends Genet (2011) 1.30
The history and enduring contributions of planarians to the study of animal regeneration. Wiley Interdiscip Rev Dev Biol (2012) 1.28
A dual platform approach to transcript discovery for the planarian Schmidtea mediterranea to establish RNAseq for stem cell and regeneration biology. PLoS One (2010) 1.16
PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. Development (2012) 1.13
Specialized progenitors and regeneration. Development (2013) 1.10
The planarian flatworm: an in vivo model for stem cell biology and nervous system regeneration. Dis Model Mech (2010) 1.09
Next generation organelles: structure and role of germ granules in the germline. Mol Reprod Dev (2012) 1.01
Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea. BMC Genomics (2010) 1.01
A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation. PLoS Negl Trop Dis (2012) 0.98
Essential elements for translation: the germline factor Vasa functions broadly in somatic cells. Development (2015) 0.87
Bacterial symbiosis maintenance in the asexually reproducing and regenerating flatworm Paracatenula galateia. PLoS One (2012) 0.83
PIWI homologs mediate histone H4 mRNA localization to planarian chromatoid bodies. Development (2014) 0.82
A proteomics approach to decipher the molecular nature of planarian stem cells. BMC Genomics (2011) 0.82
Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection. EBioMedicine (2017) 0.80
Molecular cloning and characterization of SL3: a stem cell-specific SL RNA from the planarian Schmidtea mediterranea. Gene (2013) 0.80
Proliferation pattern during rostrum regeneration of the symbiotic flatworm Paracatenula galateia: a pulse-chase-pulse analysis. Cell Tissue Res (2012) 0.79
Planarians as a model to assess in vivo the role of matrix metalloproteinase genes during homeostasis and regeneration. PLoS One (2013) 0.78
Posterior Wnts Have Distinct Roles in Specification and Patterning of the Planarian Posterior Region. Int J Mol Sci (2015) 0.78
Alternative flow cytometry strategies to analyze stem cells and cell death in planarians. Regeneration (Oxf) (2016) 0.75
Planarians sense simulated microgravity and hypergravity. Biomed Res Int (2014) 0.75
Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell (2009) 11.65
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 8.65
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell (2008) 7.79
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature (2008) 7.07
Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell (2008) 5.90
Regulatory networks in embryo-derived pluripotent stem cells. Nat Rev Mol Cell Biol (2005) 4.52
Direct reprogramming of human neural stem cells by OCT4. Nature (2009) 4.32
Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell (2012) 4.28
Derivation of oocytes from mouse embryonic stem cells. Science (2003) 4.03
Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev (2002) 3.52
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming. Cell (2010) 3.08
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev (2003) 2.99
Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell (2009) 2.78
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell (2010) 2.73
Combinatorial control of gene expression. Nat Struct Mol Biol (2004) 2.66
Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A (2006) 2.65
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell (2010) 2.58
Oct4 is required for primordial germ cell survival. EMBO Rep (2004) 2.56
Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (2009) 2.29
Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell (2009) 2.26
Identification and characterization of stem cells in prepubertal spermatogenesis in mice. Dev Biol (2003) 2.24
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell (2013) 2.22
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells. Blood (2010) 2.17
Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells (2004) 2.02
Stem cell pluripotency and transcription factor Oct4. Cell Res (2002) 1.99
Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians. Development (2008) 1.83
A central role for TFIID in the pluripotent transcription circuitry. Nature (2013) 1.82
Human adult germline stem cells in question. Nature (2010) 1.74
Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol Ther (2011) 1.69
SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic (2007) 1.66
Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation. J Biol Chem (2007) 1.65
FGF signalling inhibits neural induction in human embryonic stem cells. EMBO J (2011) 1.61
Direct reprogramming of fibroblasts into epiblast stem cells. Nat Cell Biol (2010) 1.52
The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians. Dev Biol (2007) 1.47
Absence of OCT4 expression in somatic tumor cell lines. Stem Cells (2007) 1.41
Post-translational regulation of Oct4 transcriptional activity. PLoS One (2009) 1.41
Pluripotential reprogramming of the somatic genome in hybrid cells occurs with the first cell cycle. Stem Cells (2007) 1.37
Progeny from sperm obtained after ectopic grafting of neonatal mouse testes. Biol Reprod (2003) 1.31
A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture. Gene (2002) 1.28
Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation. Stem Cells (2015) 1.27
The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes. Mol Biol Cell (2003) 1.27
Noggin and noggin-like genes control dorsoventral axis regeneration in planarians. Curr Biol (2011) 1.25
Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution? Evol Dev (2003) 1.23
The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion. J Biol Chem (2002) 1.23
Regulation of developmental lymphangiogenesis by Syk(+) leukocytes. Dev Cell (2010) 1.22
Distinct developmental ground states of epiblast stem cell lines determine different pluripotency features. Stem Cells (2011) 1.21
Variable reprogramming of the pluripotent stem cell marker Oct4 in mouse clones: distinct developmental potentials in different culture environments. Stem Cells (2005) 1.21
Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1. Cell Res (2011) 1.20
Nanog: a new recruit to the embryonic stem cell orchestra. Cell (2003) 1.20
Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J (2012) 1.19
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling. PLoS One (2013) 1.18
The caudal-related protein cdx2 promotes trophoblast differentiation of mouse embryonic stem cells. Stem Cells (2005) 1.17
Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology? Oncogene (2004) 1.16
CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis. Blood (2010) 1.16
Concise review: Oct4 and more: the reprogramming expressway. Stem Cells (2012) 1.16
Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions. PLoS One (2012) 1.15
Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation. J Biol Chem (2004) 1.14
Gradients in planarian regeneration and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.14
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. Nat Commun (2013) 1.12
Parthenogenetic stem cells for tissue-engineered heart repair. J Clin Invest (2013) 1.11
The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration. Dev Genes Evol (2007) 1.10
Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2. Development (2010) 1.10
p53 connects tumorigenesis and reprogramming to pluripotency. J Exp Med (2010) 1.09
A unique Oct4 interface is crucial for reprogramming to pluripotency. Nat Cell Biol (2013) 1.08
Generation of induced pluripotent stem cells from neural stem cells. Nat Protoc (2009) 1.07
Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke. Stroke (2011) 1.07
Differential activity by DNA-induced quarternary structures of POU transcription factors. Biochem Pharmacol (2002) 1.07
Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. J Biol Chem (2010) 1.06
Induction of pluripotency in human cord blood unrestricted somatic stem cells. Exp Hematol (2010) 1.06
Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells. Nat Protoc (2010) 1.06
Induced pluripotent stem cells at nanoscale. Stem Cells Dev (2010) 1.05
Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells. Cytometry A (2011) 1.05
Epigenetic hierarchy governing Nestin expression. Stem Cells (2009) 1.05
Establishment of totipotency does not depend on Oct4A. Nat Cell Biol (2013) 1.05
Djeyes absent (Djeya) controls prototypic planarian eye regeneration by cooperating with the transcription factor Djsix-1. Dev Biol (2004) 1.03
The genetic network of prototypic planarian eye regeneration is Pax6 independent. Development (2002) 1.03
Annexin A8 regulates late endosome organization and function. Mol Biol Cell (2008) 1.03
Early planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway. Dev Biol (2011) 1.02