Published in Trends Biochem Sci on December 01, 2004
Exploring the human genome with functional maps. Genome Res (2009) 2.69
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Mol Biol Cell (2006) 2.02
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90
Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs. Mol Biol Cell (2010) 1.89
BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor. Curr Biol (2012) 1.74
Cellular functions of NSF: not just SNAPs and SNAREs. FEBS Lett (2007) 1.42
A SNARE complex unique to seed plants is required for protein storage vacuole biogenesis and seed development of Arabidopsis thaliana. Plant Cell (2008) 1.38
Increases in the number of SNARE genes parallels the rise of multicellularity among the green plants. Plant Physiol (2007) 1.34
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. Open Biol (2012) 1.29
Role of HRB in clathrin-dependent endocytosis. J Biol Chem (2008) 1.28
Cdc42 and actin control polarized expression of TI-VAMP vesicles to neuronal growth cones and their fusion with the plasma membrane. Mol Biol Cell (2005) 1.26
Separate inputs modulate phosphorylation-dependent and -independent type VI secretion activation. Mol Microbiol (2011) 1.25
Molecular complexes that direct rhodopsin transport to primary cilia. Prog Retin Eye Res (2013) 1.16
The secretory system of Arabidopsis. Arabidopsis Book (2008) 1.16
Longin-like folds identified in CHiPS and DUF254 proteins: vesicle trafficking complexes conserved in eukaryotic evolution. Protein Sci (2006) 1.15
SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery. Mol Biol Cell (2008) 1.13
The Tetrahymena thermophila phagosome proteome. Eukaryot Cell (2006) 1.11
SNARE complexes of different composition jointly mediate membrane fusion in Arabidopsis cytokinesis. Mol Biol Cell (2013) 1.04
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein. Mol Biol Cell (2006) 0.98
Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex. Dev Cell (2012) 0.96
The SNARE Ykt6 is released from yeast vacuoles during an early stage of fusion. EMBO Rep (2005) 0.96
Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. Blood (2012) 0.95
Arabidopsis R-SNARE proteins VAMP721 and VAMP722 are required for cell plate formation. PLoS One (2011) 0.95
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels. Biochem J (2009) 0.93
The SNARE protein family of Leishmania major. BMC Genomics (2006) 0.92
Comparative analysis of plant genomes allows the definition of the "Phytolongins": a novel non-SNARE longin domain protein family. BMC Genomics (2009) 0.89
The longin SNARE VAMP7/TI-VAMP adopts a closed conformation. J Biol Chem (2010) 0.88
Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology. Pharmacol Rev (2017) 0.87
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation. PLoS One (2013) 0.87
The role of non-canonical SNAREs in synaptic vesicle recycling. Cell Logist (2012) 0.85
Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi. BMC Evol Biol (2009) 0.84
Myocilin, a component of a membrane-associated protein complex driven by a homologous Q-SNARE domain. Biochemistry (2012) 0.82
A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency. BMC Med Genet (2014) 0.81
The pollen-specific R-SNARE/longin PiVAMP726 mediates fusion of endo- and exocytic compartments in pollen tube tip growth. J Exp Bot (2012) 0.81
A comparative analysis of trypanosomatid SNARE proteins. Parasitol Int (2013) 0.81
Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. EMBO J (2016) 0.80
VAMP-7 links granule exocytosis to actin reorganization during platelet activation. Blood (2015) 0.80
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain. Sci Rep (2016) 0.79
The longin domain regulates the steady-state dynamics of Sec22 in Plasmodium falciparum. Eukaryot Cell (2009) 0.78
Distinct subcellular localization of a group of synaptobrevin-like SNAREs in Paramecium tetraurelia and effects of silencing SNARE-specific chaperone NSF. Eukaryot Cell (2009) 0.77
On the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from Genotype. Trends Cell Biol (2016) 0.77
VAMP7 modulates ciliary biogenesis in kidney cells. PLoS One (2014) 0.77
VAMP721 conformations unmask an extended motif for K+ channel binding and gating control. Plant Physiol (2016) 0.75
Subcellular localization and trafficking of phytolongins (non-SNARE longins) in the plant secretory pathway. J Exp Bot (2016) 0.75
Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. BMC Mol Biol (2011) 0.75
Functional Analysis of Developmentally Regulated Genes chs7 and sec22 in the Ascomycete Sordaria macrospora. G3 (Bethesda) (2015) 0.75
Discovering vesicle traffic network constraints by model checking. PLoS One (2017) 0.75
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol (2002) 3.36
Rethinking 'secondary' metabolism: physiological roles for phenazine antibiotics. Nat Chem Biol (2006) 2.86
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity (2004) 2.47
The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. Dev Cell (2007) 2.44
Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia. Lancet (2003) 2.39
Leucyl-tRNA synthetase controls TORC1 via the EGO complex. Mol Cell (2012) 2.37
Retroviral genomic RNAs are transported to the plasma membrane by endosomal vesicles. Dev Cell (2003) 2.22
The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol (2010) 2.19
Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J Biol Chem (2004) 2.17
Pyocyanin alters redox homeostasis and carbon flux through central metabolic pathways in Pseudomonas aeruginosa PA14. J Bacteriol (2007) 1.95
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol (2005) 1.85
Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria. Cell Rep (2013) 1.82
Signal-mediated dynamic retention of glycosyltransferases in the Golgi. Science (2008) 1.71
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex. Proc Natl Acad Sci U S A (2012) 1.66
A cycle of Vam7p release from and PtdIns 3-P-dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion. J Cell Biol (2002) 1.62
CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion. J Cell Sci (2013) 1.56
SNAP-25 modulation of calcium dynamics underlies differences in GABAergic and glutamatergic responsiveness to depolarization. Neuron (2004) 1.56
MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Curr Biol (2008) 1.55
Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex. Traffic (2010) 1.53
On the mechanism of protein palmitoylation. EMBO Rep (2004) 1.52
Rab cascades and tethering factors in the endomembrane system. FEBS Lett (2007) 1.47
Multisubunit tethering complexes and their role in membrane fusion. Curr Biol (2010) 1.46
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking. FEBS Lett (2009) 1.40
Yeast vacuole fusion: a model system for eukaryotic endomembrane dynamics. Autophagy (2007) 1.35
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A (2006) 1.28
Role of HRB in clathrin-dependent endocytosis. J Biol Chem (2008) 1.28
Cdc42 and actin control polarized expression of TI-VAMP vesicles to neuronal growth cones and their fusion with the plasma membrane. Mol Biol Cell (2005) 1.26
Vps41 phosphorylation and the Rab Ypt7 control the targeting of the HOPS complex to endosome-vacuole fusion sites. Mol Biol Cell (2009) 1.26
The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments. Mol Biol Cell (2009) 1.23
A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery. Dev Cell (2012) 1.22
v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. J Cell Biol (2007) 1.21
VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites. Nat Immunol (2013) 1.21
HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites. Mol Biol Cell (2011) 1.21
Phenazines affect biofilm formation by Pseudomonas aeruginosa in similar ways at various scales. Res Microbiol (2010) 1.19
The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion. EMBO J (2003) 1.19
Control of Candida albicans metabolism and biofilm formation by Pseudomonas aeruginosa phenazines. MBio (2013) 1.18
Confocal imaging and tracking of the exocytotic routes for D-serine-mediated gliotransmission. Glia (2008) 1.15
Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells. Eur J Immunol (2008) 1.15
Self-interaction of a SNARE transmembrane domain promotes the hemifusion-to-fusion transition. J Mol Biol (2006) 1.15
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8. Proc Natl Acad Sci U S A (2005) 1.15
Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion. Proc Natl Acad Sci U S A (2005) 1.15
Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two-step reaction mechanism. Traffic (2009) 1.14
The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome. J Cell Sci (2010) 1.13
Computer-aided biotechnology: from immuno-informatics to reverse vaccinology. Trends Biotechnol (2008) 1.13
Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins. Biochim Biophys Acta (2003) 1.11
Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration. Biol Cell (2007) 1.11
Dynamic interaction of amphiphysin with N-WASP regulates actin assembly. J Biol Chem (2009) 1.10
DNA binding shifts the redox potential of the transcription factor SoxR. Proc Natl Acad Sci U S A (2008) 1.10
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep (2009) 1.10
Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity. Proc Natl Acad Sci U S A (2012) 1.10
The tetanus neurotoxin-sensitive and insensitive routes to and from the plasma membrane: fast and slow pathways? Traffic (2005) 1.08
DNA methylation 40 years later: Its role in human health and disease. J Cell Physiol (2005) 1.08
Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins. J Biol Chem (2008) 1.07
Chromosome territory reorganization in a human disease with altered DNA methylation. Proc Natl Acad Sci U S A (2007) 1.06
What is the function of neuronal AP-3? Biol Cell (2007) 1.05
Distinct v-SNAREs regulate direct and indirect apical delivery in polarized epithelial cells. J Cell Sci (2007) 1.05
Palmitoylation determines the function of Vac8 at the yeast vacuole. J Cell Sci (2006) 1.03
The transmembrane domain of Vam3 affects the composition of cis- and trans-SNARE complexes to promote homotypic vacuole fusion. J Biol Chem (2002) 1.03
Cross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion. Mol Biol Cell (2003) 1.03
Ectopic expression of syntaxin 1 in the ER redirects TI-VAMP- and cellubrevin-containing vesicles. J Cell Sci (2003) 1.03
The syntaxins SYP31 and SYP81 control ER-Golgi trafficking in the plant secretory pathway. Traffic (2008) 1.03
Fast turnover of L1 adhesions in neuronal growth cones involving both surface diffusion and exo/endocytosis of L1 molecules. Mol Biol Cell (2007) 1.02
Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP. Mol Biol Cell (2004) 1.01
Membrane dynamics and fusion at late endosomes and vacuoles--Rab regulation, multisubunit tethering complexes and SNAREs. Eur J Cell Biol (2011) 1.00
Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesis. J Biol Chem (2012) 1.00
Epigenetic alteration of microRNAs in DNMT3B-mutated patients of ICF syndrome. Epigenetics (2010) 0.99
Atg18 function in autophagy is regulated by specific sites within its β-propeller. J Cell Sci (2012) 0.98
The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes. Proc Natl Acad Sci U S A (2013) 0.98
Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes. Hum Mol Genet (2002) 0.98
Weak effect of membrane diffusion on the rate of receptor accumulation at adhesive contacts. Biophys J (2005) 0.98
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein. Mol Biol Cell (2006) 0.98
Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci (2012) 0.97
NERVE: new enhanced reverse vaccinology environment. BMC Biotechnol (2006) 0.97
F₄-neuroprostanes mediate neurological severity in Rett syndrome. Clin Chim Acta (2011) 0.97
Function and regulation of the endosomal fusion and fission machineries. Cold Spring Harb Perspect Biol (2014) 0.96
Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling. J Cell Sci (2010) 0.96
Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae. Biochem J (2004) 0.96
Guanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases. J Biol Chem (2013) 0.96
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. J Cell Sci (2014) 0.96
Complex events in the evolution of the human pseudoautosomal region 2 (PAR2). Genome Res (2003) 0.96
The SNARE Ykt6 is released from yeast vacuoles during an early stage of fusion. EMBO Rep (2005) 0.96
Identification of the amino acid residues rendering TI-VAMP insensitive toward botulinum neurotoxin B. J Mol Biol (2006) 0.95
The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell (2012) 0.94
Purification and in vitro analysis of yeast vacuoles. Methods Enzymol (2008) 0.94
Increased levels of 4HNE-protein plasma adducts in Rett syndrome. Clin Biochem (2011) 0.93
F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome. J Lipid Res (2011) 0.93
A conserved N-terminal arginine-motif in GOLPH3-family proteins mediates binding to coatomer. Traffic (2012) 0.93
The cell outgrowth secretory endosome (COSE): a specialized compartment involved in neuronal morphogenesis. Biol Cell (2003) 0.93
Quantifying neurite growth mediated by interactions among secretory vesicles, microtubules, and actin networks. Biophys J (2009) 0.92