Published in EMBO J on December 11, 2003
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A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion. EMBO J (2004) 1.65
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Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation. Proc Natl Acad Sci U S A (2004) 1.28
The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. J Cell Biol (2005) 1.24
Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion. EMBO J (2007) 1.19
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An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p. Science (2001) 1.51
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Vac8p release from the SNARE complex and its palmitoylation are coupled and essential for vacuole fusion. EMBO J (2001) 1.44
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Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain. Mol Biol Cell (2003) 1.22
Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion. J Cell Biol (2002) 1.20
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Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem (2001) 1.16
Yeast Golgi SNARE interactions are promiscuous. J Cell Sci (2000) 1.16
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The docking of primed vacuoles can be reversibly arrested by excess Sec17p (alpha-SNAP). J Biol Chem (2000) 1.07
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A novel cold-sensitive allele of the rate-limiting enzyme of fatty acid synthesis, acetyl coenzyme A carboxylase, affects the morphology of the yeast vacuole through acylation of Vac8p. Mol Cell Biol (2000) 0.98
Ykt6p is a multifunctional yeast R-SNARE that is required for multiple membrane transport pathways to the vacuole. Mol Biol Cell (2003) 0.94
Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates. Biochim Biophys Acta (2000) 0.89
Biochemical characterization of the vacuolar palmitoyl acyltransferase. FEBS Lett (2003) 0.88
Characterization of the sequence and expression of a Ykt6 prenylated SNARE from rat. DNA Cell Biol (1999) 0.78
The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. Dev Cell (2007) 2.44
Leucyl-tRNA synthetase controls TORC1 via the EGO complex. Mol Cell (2012) 2.37
The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol (2010) 2.19
The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol (2005) 1.85
Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex. Proc Natl Acad Sci U S A (2012) 1.66
Longins and their longin domains: regulated SNAREs and multifunctional SNARE regulators. Trends Biochem Sci (2004) 1.65
A cycle of Vam7p release from and PtdIns 3-P-dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion. J Cell Biol (2002) 1.62
CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion. J Cell Sci (2013) 1.56
Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex. Traffic (2010) 1.53
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Rab cascades and tethering factors in the endomembrane system. FEBS Lett (2007) 1.47
Multisubunit tethering complexes and their role in membrane fusion. Curr Biol (2010) 1.46
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Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
Vps41 phosphorylation and the Rab Ypt7 control the targeting of the HOPS complex to endosome-vacuole fusion sites. Mol Biol Cell (2009) 1.26
The CORVET subunit Vps8 cooperates with the Rab5 homolog Vps21 to induce clustering of late endosomal compartments. Mol Biol Cell (2009) 1.23
HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites. Mol Biol Cell (2011) 1.21
Self-interaction of a SNARE transmembrane domain promotes the hemifusion-to-fusion transition. J Mol Biol (2006) 1.15
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8. Proc Natl Acad Sci U S A (2005) 1.15
Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two-step reaction mechanism. Traffic (2009) 1.14
The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome. J Cell Sci (2010) 1.13
The relevance of salt bridges for the stability of the influenza virus hemagglutinin. FASEB J (2007) 1.13
Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins. Biochim Biophys Acta (2003) 1.11
Electron cryomicroscopy reveals different F1+F2 protein States in intact parainfluenza virions. J Virol (2008) 1.10
Palmitoylation determines the function of Vac8 at the yeast vacuole. J Cell Sci (2006) 1.03
The transmembrane domain of Vam3 affects the composition of cis- and trans-SNARE complexes to promote homotypic vacuole fusion. J Biol Chem (2002) 1.03
FLIM-FRET and FRAP reveal association of influenza virus haemagglutinin with membrane rafts. Biochem J (2010) 1.03
Membrane dynamics and fusion at late endosomes and vacuoles--Rab regulation, multisubunit tethering complexes and SNAREs. Eur J Cell Biol (2011) 1.00
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Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesis. J Biol Chem (2012) 1.00
Atg18 function in autophagy is regulated by specific sites within its β-propeller. J Cell Sci (2012) 0.98
The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes. Proc Natl Acad Sci U S A (2013) 0.98
Function and regulation of the endosomal fusion and fission machineries. Cold Spring Harb Perspect Biol (2014) 0.96
Guanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases. J Biol Chem (2013) 0.96
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. J Cell Sci (2014) 0.96
The SNARE Ykt6 is released from yeast vacuoles during an early stage of fusion. EMBO Rep (2005) 0.96
Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae. Biochem J (2004) 0.96
Hemagglutinin of influenza virus partitions into the nonraft domain of model membranes. Biophys J (2010) 0.95
The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell (2012) 0.94
Purification and in vitro analysis of yeast vacuoles. Methods Enzymol (2008) 0.94
The polybasic region is not essential for membrane binding of the matrix protein M1 of influenza virus. Virology (2008) 0.93
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Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite. Traffic (2012) 0.92
Endocytic Rabs in membrane trafficking and signaling. Biol Chem (2014) 0.91
Farnesylation of the SNARE protein Ykt6 increases its stability and helical folding. J Mol Biol (2008) 0.91
Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability. Proc Natl Acad Sci U S A (2006) 0.91
An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking. Traffic (2011) 0.90
Rab GTPases and tethering in the yeast endocytic pathway. Small GTPases (2011) 0.90
Depalmitoylation of Ykt6 prevents its entry into the multivesicular body pathway. Traffic (2008) 0.89
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The vacuolar V1/V0-ATPase is involved in the release of the HOPS subunit Vps41 from vacuoles, vacuole fragmentation and fusion. FEBS Lett (2008) 0.88
Biochemical characterization of the vacuolar palmitoyl acyltransferase. FEBS Lett (2003) 0.88
Guiding endosomal maturation. Cell (2010) 0.88
The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3. J Cell Biol (2013) 0.87
Equine arteritis virus is delivered to an acidic compartment of host cells via clathrin-dependent endocytosis. Virology (2008) 0.86
ATP-independent control of Vac8 palmitoylation by a SNARE subcomplex on yeast vacuoles. J Biol Chem (2005) 0.86
Intrinsic membrane association of the cytoplasmic tail of influenza virus M2 protein and lateral membrane sorting regulated by cholesterol binding and palmitoylation. Biochem J (2011) 0.86
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The N-terminal domains of Vps3 and Vps8 are critical for localization and function of the CORVET tethering complex on endosomes. PLoS One (2013) 0.85
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Intrinsic cytoskeleton-dependent clustering of influenza virus M2 protein with hemagglutinin assessed by FLIM-FRET. J Virol (2010) 0.85
The yeast Batten disease orthologue Btn1 controls endosome-Golgi retrograde transport via SNARE assembly. J Cell Biol (2011) 0.85
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In vitro selection of self-interacting transmembrane segments--membrane proteins approached from a different perspective. IUBMB Life (2002) 0.81
Probing protein palmitoylation at the yeast vacuole. Methods (2006) 0.80
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