Published in Proc Natl Acad Sci U S A on July 09, 2003
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol (2009) 4.16
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Mol Biol Cell (2006) 2.02
Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb. Cell (2008) 1.75
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell (2011) 1.66
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. Mol Biol Cell (2006) 1.64
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep (2004) 1.62
Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic. Mol Biol Cell (2008) 1.58
v-SNARE composition distinguishes synaptic vesicle pools. Neuron (2011) 1.54
Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. J Biol Chem (2008) 1.45
Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles. Mol Biol Cell (2005) 1.40
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. Dev Cell (2013) 1.36
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A (2006) 1.28
Role of HRB in clathrin-dependent endocytosis. J Biol Chem (2008) 1.28
Cdc42 and actin control polarized expression of TI-VAMP vesicles to neuronal growth cones and their fusion with the plasma membrane. Mol Biol Cell (2005) 1.26
Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles. Mol Biol Cell (2009) 1.22
v-SNARE cellubrevin is required for basolateral sorting of AP-1B-dependent cargo in polarized epithelial cells. J Cell Biol (2007) 1.21
AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. EMBO Rep (2003) 1.17
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep (2009) 1.10
Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion. EMBO Rep (2015) 1.09
Cross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion. Mol Biol Cell (2003) 1.03
SNAP25, but not syntaxin 1A, recycles via an ARF6-regulated pathway in neuroendocrine cells. Mol Biol Cell (2005) 1.03
Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids. Mol Phylogenet Evol (2013) 1.02
Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes. J Biol Chem (2010) 1.02
Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP. Mol Biol Cell (2004) 1.01
The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation. Nat Struct Mol Biol (2012) 1.01
Characterization of hepatitis C virus core protein multimerization and membrane envelopment: revelation of a cascade of core-membrane interactions. J Virol (2009) 1.01
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface. Dev Cell (2014) 0.98
Discovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-II. Small GTPases (2013) 0.98
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein. Mol Biol Cell (2006) 0.98
Coiled-coil interactions are required for post-Golgi R-SNARE trafficking. EMBO Rep (2009) 0.98
Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival. J Biol Chem (2008) 0.96
Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex. Dev Cell (2012) 0.96
Disassembly of all SNARE complexes by N-ethylmaleimide-sensitive factor (NSF) is initiated by a conserved 1:1 interaction between α-soluble NSF attachment protein (SNAP) and SNARE complex. J Biol Chem (2013) 0.95
Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A (2011) 0.95
A second SNARE role for exocytic SNAP25 in endosome fusion. Mol Biol Cell (2006) 0.92
Tumor protein D52 expression and Ca2+-dependent phosphorylation modulates lysosomal membrane protein trafficking to the plasma membrane. Am J Physiol Cell Physiol (2009) 0.91
Comparative analysis of plant genomes allows the definition of the "Phytolongins": a novel non-SNARE longin domain protein family. BMC Genomics (2009) 0.89
The longin SNARE VAMP7/TI-VAMP adopts a closed conformation. J Biol Chem (2010) 0.88
Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation. PLoS One (2013) 0.87
BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers. J Cell Biol (2016) 0.87
Molecular underpinnings of synaptic vesicle pool heterogeneity. Traffic (2015) 0.85
The Arabidopsis R-SNARE VAMP721 Interacts with KAT1 and KC1 K+ Channels to Moderate K+ Current at the Plasma Membrane. Plant Cell (2015) 0.83
Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles. Cold Spring Harb Perspect Biol (2013) 0.83
Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran. Inflamm Res (2010) 0.82
The pollen-specific R-SNARE/longin PiVAMP726 mediates fusion of endo- and exocytic compartments in pollen tube tip growth. J Exp Bot (2012) 0.81
Endosomal sorting of VAMP3 is regulated by PI4K2A. J Cell Sci (2014) 0.81
Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation. Mol Cell Biol (2015) 0.81
Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain. J Biol Chem (2013) 0.80
Rab32 is essential for maintaining functional acidocalcisomes, and for growth and infectivity of Trypanosoma cruzi. J Cell Sci (2015) 0.80
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis. Mol Biol Cell (2013) 0.79
AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes. PLoS One (2012) 0.79
Mycobacterium avium MAV_2941 mimics phosphoinositol-3-kinase to interfere with macrophage phagosome maturation. Microbes Infect (2015) 0.78
The longin domain regulates the steady-state dynamics of Sec22 in Plasmodium falciparum. Eukaryot Cell (2009) 0.78
VAMP7 modulates ciliary biogenesis in kidney cells. PLoS One (2014) 0.77
p115-SNARE interactions: a dynamic cycle of p115 binding monomeric SNARE motifs and releasing assembled bundles. Traffic (2015) 0.76
The Q-soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-associated Membrane Proteins (VAMPs). J Biol Chem (2015) 0.76
Subcellular Trafficking of Mammalian Lysosomal Proteins: An Extended View. Int J Mol Sci (2016) 0.76
Lipid Regulated Intramolecular Conformational Dynamics of SNARE-Protein Ykt6. Sci Rep (2016) 0.75
Mapping of the spontaneous deletion in the Ap3d1 gene of mocha mice: fast and reliable genotyping. BMC Res Notes (2008) 0.75
Subcellular localization and trafficking of phytolongins (non-SNARE longins) in the plant secretory pathway. J Exp Bot (2016) 0.75
Adaptor protein-3: A key player in RBL-2H3 mast cell mediator release. PLoS One (2017) 0.75
Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. BMC Mol Biol (2011) 0.75
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Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor. Mol Cell (1999) 4.67
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Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. Proc Natl Acad Sci U S A (1999) 3.16
Characterization of the adaptor-related protein complex, AP-3. J Cell Biol (1997) 2.76
Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron (1998) 2.73
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Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. Science (1998) 2.14
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells. Mol Biol Cell (1998) 2.11
VAMP-7 mediates vesicular transport from endosomes to lysosomes. J Cell Biol (1999) 2.01
Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells. Proc Natl Acad Sci U S A (1999) 1.95
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth. J Cell Biol (2000) 1.82
Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE. J Cell Biol (1998) 1.58
The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding. J Biol Chem (2001) 1.57
An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p. Science (2001) 1.51
Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain. Trends Biochem Sci (2001) 1.41
Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell. Nat Med (2002) 1.35
The delta subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface. Proc Natl Acad Sci U S A (2002) 1.32
A common exocytotic mechanism mediates axonal and dendritic outgrowth. J Neurosci (2001) 1.31
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The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes. J Neurosci (2001) 1.22
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain. Mol Biol Cell (2003) 1.22
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A novel snare N-terminal domain revealed by the crystal structure of Sec22b. J Biol Chem (2001) 1.17
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The protein tyrosine kinase Hck is located on lysosomal vesicles that are physically and functionally distinct from CD63-positive lysosomes in human macrophages. J Cell Sci (2002) 1.07
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NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
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Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 4.94
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Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J (2002) 3.53
Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature (2007) 3.51
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TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
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Functional proteomics mapping of a human signaling pathway. Genome Res (2004) 3.04
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Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. Dev Cell (2005) 2.75
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity (2004) 2.47
Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia. Lancet (2003) 2.39
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell (2011) 2.34
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Retroviral genomic RNAs are transported to the plasma membrane by endosomal vesicles. Dev Cell (2003) 2.22
Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J Biol Chem (2004) 2.17
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AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
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Regulation of Notch signalling by non-visual beta-arrestin. Nat Cell Biol (2005) 1.79
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TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
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Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60
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Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
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An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. PLoS Biol (2009) 1.48
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The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation. EMBO J (2004) 1.41
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