Published in J Bacteriol on December 01, 2004
Genome-scale analysis of escherichia coli FNR reveals complex features of transcription factor binding. PLoS Genet (2013) 1.28
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR. Proc Natl Acad Sci U S A (2007) 1.27
The O2 sensitivity of the transcription factor FNR is controlled by Ser24 modulating the kinetics of [4Fe-4S] to [2Fe-2S] conversion. Proc Natl Acad Sci U S A (2009) 1.15
Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli. Mol Microbiol (2012) 1.12
Comparative genomic analysis of regulation of anaerobic respiration in ten genomes from three families of gamma-proteobacteria (Enterobacteriaceae, Pasteurellaceae, Vibrionaceae). BMC Genomics (2007) 1.10
Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein. Proc Natl Acad Sci U S A (2012) 1.09
Iron-containing transcription factors and their roles as sensors. Curr Opin Chem Biol (2011) 1.07
The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets. BMC Microbiol (2011) 1.05
Bacterial iron-sulfur regulatory proteins as biological sensor-switches. Antioxid Redox Signal (2012) 1.05
Characterization of [4Fe-4S]-containing and cluster-free forms of Streptomyces WhiD. Biochemistry (2009) 1.04
Contributions of [4Fe-4S]-FNR and integration host factor to fnr transcriptional regulation. J Bacteriol (2007) 1.03
Deletion of genes encoding cytochrome oxidases and quinol monooxygenase blocks the aerobic-anaerobic shift in Escherichia coli K-12 MG1655. Appl Environ Microbiol (2010) 0.98
Phenotypic repertoire of the FNR regulatory network in Escherichia coli. Mol Microbiol (2010) 0.97
Regulation of aerobic-to-anaerobic transitions by the FNR cycle in Escherichia coli. J Mol Biol (2010) 0.95
Reduced apo-fumarate nitrate reductase regulator (apoFNR) as the major form of FNR in aerobically growing Escherichia coli. J Bacteriol (2007) 0.90
Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide. Virulence (2014) 0.88
X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters. Proc Natl Acad Sci U S A (2013) 0.87
Binding to DNA protects Neisseria meningitidis fumarate and nitrate reductase regulator (FNR) from oxygen. J Biol Chem (2009) 0.87
Aspartate 141 is the fourth ligand of the oxygen-sensing [4Fe-4S]2+ cluster of Bacillus subtilis transcriptional regulator Fnr. J Biol Chem (2010) 0.85
Posttranslational control of transcription factor FixK2, a key regulator for the Bradyrhizobium japonicum-soybean symbiosis. Proc Natl Acad Sci U S A (2009) 0.85
Iron-based redox switches in biology. Antioxid Redox Signal (2009) 0.85
Fe-S proteins that regulate gene expression. Biochim Biophys Acta (2014) 0.83
Astaxanthin as a Potential Neuroprotective Agent for Neurological Diseases. Mar Drugs (2015) 0.82
Oxygen sensing strategies in mammals and bacteria. J Inorg Biochem (2014) 0.81
Coordinate regulation of the Suf and Isc Fe-S cluster biogenesis pathways by IscR is essential for viability of Escherichia coli. J Bacteriol (2014) 0.80
Design principles of a conditional futile cycle exploited for regulation. Mol Biosyst (2015) 0.79
Impact of Anaerobiosis on Expression of the Iron-Responsive Fur and RyhB Regulons. MBio (2015) 0.78
In vivo demonstration of FNR dimers in response to lower O(2) availability. J Bacteriol (2007) 0.78
The oxygen sensor MgFnr controls magnetite biomineralization by regulation of denitrification in Magnetospirillum gryphiswaldense. BMC Microbiol (2014) 0.78
The PqrR transcriptional repressor of Pseudomonas aeruginosa transduces redox signals via an iron-containing prosthetic group. J Bacteriol (2009) 0.78
Influence of association state and DNA binding on the O₂-reactivity of [4Fe-4S] fumarate and nitrate reduction (FNR) regulator. Biochem J (2014) 0.77
Response of the oxygen sensor NreB to air in vivo: Fe-S-containing NreB and apo-NreB in aerobically and anaerobically growing Staphylococcus carnosus. J Bacteriol (2010) 0.77
Transcriptome-Level Signatures in Gene Expression and Gene Expression Variability during Bacterial Adaptive Evolution. mSphere (2017) 0.75
The biology of oxygen radicals. Science (1978) 13.21
Semi-micro methods for analysis of labile sulfide and of labile sulfide plus sulfane sulfur in unusually stable iron-sulfur proteins. Anal Biochem (1983) 4.26
The inactivation of Fe-S cluster containing hydro-lyases by superoxide. J Biol Chem (1993) 3.43
Assay of metabolic superoxide production in Escherichia coli. J Biol Chem (1991) 3.43
DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen. J Biol Chem (1996) 2.74
Effect of microaerophilic cell growth conditions on expression of the aerobic (cyoABCDE and cydAB) and anaerobic (narGHJI, frdABCD, and dmsABC) respiratory pathway genes in Escherichia coli. J Bacteriol (1996) 2.54
Iron-sulfur cluster disassembly in the FNR protein of Escherichia coli by O2: [4Fe-4S] to [2Fe-2S] conversion with loss of biological activity. Proc Natl Acad Sci U S A (1997) 2.38
Global gene expression profiling in Escherichia coli K12. The effects of oxygen availability and FNR. J Biol Chem (2003) 2.32
Oxygen permeability of phosphatidylcholine--cholesterol membranes. Proc Natl Acad Sci U S A (1989) 2.14
Function of trigger factor and DnaK in multidomain protein folding: increase in yield at the expense of folding speed. Cell (2004) 1.85
Reconstitution of the [4Fe-4S] cluster in FNR and demonstration of the aerobic-anaerobic transcription switch in vitro. Biochem J (1996) 1.78
Effect of temperature on in vivo protein synthetic capacity in Escherichia coli. J Bacteriol (1998) 1.62
O2-sensing and O2-dependent gene regulation in facultatively anaerobic bacteria. Arch Microbiol (1995) 1.49
Mechanism of oxygen sensing by the bacterial transcription factor fumarate-nitrate reduction (FNR). J Biol Chem (2003) 1.47
FNR is a direct oxygen sensor having a biphasic response curve. FEBS Lett (1997) 1.46
Bacterial growth: constant obsession with dN/dt. J Bacteriol (1999) 1.46
On the role of cyclic AMP and the Fnr protein in Escherichia coli growing anaerobically. Arch Microbiol (1987) 1.44
O2 as the regulatory signal for FNR-dependent gene regulation in Escherichia coli. J Bacteriol (1996) 1.42
Substitution of leucine 28 with histidine in the Escherichia coli transcription factor FNR results in increased stability of the [4Fe-4S](2+) cluster to oxygen. J Biol Chem (2000) 1.30
In vitro analysis of a constitutively active mutant form of the Escherichia coli global transcription factor FNR. J Mol Biol (1995) 1.28
Effect of cell growth rate on expression of the anaerobic respiratory pathway operons frdABCD, dmsABC, and narGHJI of Escherichia coli. J Bacteriol (1994) 1.26
Mössbauer spectroscopy as a tool for the study of activation/inactivation of the transcription regulator FNR in whole cells of Escherichia coli. Proc Natl Acad Sci U S A (1998) 1.26
Superoxide destroys the [2Fe-2S]2+ cluster of FNR from Escherichia coli. Biochemistry (2004) 1.25
Control of FNR function of Escherichia coli by O2 and reducing conditions. J Mol Microbiol Biotechnol (2002) 1.22
Characterization of the dimerization domain in the FNR transcription factor. J Biol Chem (2001) 1.12
Reversible interconversion of the functional state of the gene regulator FNR from Escherichia coli in vivo by O2 and iron availability. Arch Microbiol (1991) 1.10
FNR-dependent repression of ndh gene expression requires two upstream FNR-binding sites. Microbiology (1997) 1.07
FNR-dependent activation of the class II dmsA and narG promoters of Escherichia coli requires FNR-activating regions 1 and 3. Mol Microbiol (2000) 1.07
Characterization of activating region 3 from Escherichia coli FNR. J Mol Biol (2002) 0.91
Techniques for studying the oxygen-sensitive transcription factor FNR from Escherichia coli. Methods Enzymol (2003) 0.87
Genome-wide expression analysis indicates that FNR of Escherichia coli K-12 regulates a large number of genes of unknown function. J Bacteriol (2005) 2.56
IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O2-regulated genes in Escherichia coli. Mol Microbiol (2006) 2.26
The role of Fe-S proteins in sensing and regulation in bacteria. Curr Opin Microbiol (2003) 2.17
ClpXP-dependent proteolysis of FNR upon loss of its O2-sensing [4Fe-4S] cluster. J Mol Biol (2005) 1.31
Genome-scale analysis of escherichia coli FNR reveals complex features of transcription factor binding. PLoS Genet (2013) 1.28
Superoxide destroys the [2Fe-2S]2+ cluster of FNR from Escherichia coli. Biochemistry (2004) 1.25
Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli. Mol Microbiol (2012) 1.12
The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally. PLoS Genet (2013) 1.08
Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration. EMBO J (2007) 1.07
Iron-containing transcription factors and their roles as sensors. Curr Opin Chem Biol (2011) 1.07
Reconstruction of the core and extended regulons of global transcription factors. PLoS Genet (2010) 1.06
Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat Struct Mol Biol (2013) 1.05
Characterization of the [2Fe-2S] cluster of Escherichia coli transcription factor IscR. Biochemistry (2012) 1.05
Contributions of [4Fe-4S]-FNR and integration host factor to fnr transcriptional regulation. J Bacteriol (2007) 1.03
Complex physiology and compound stress responses during fermentation of alkali-pretreated corn stover hydrolysate by an Escherichia coli ethanologen. Appl Environ Microbiol (2012) 1.00
The impact of O(2) on the Fe-S cluster biogenesis requirements of Escherichia coli FNR. J Mol Biol (2008) 1.00
Regulation of FNR dimerization by subunit charge repulsion. J Biol Chem (2006) 1.00
Characterization of activating region 3 from Escherichia coli FNR. J Mol Biol (2002) 0.91
Techniques for studying the oxygen-sensitive transcription factor FNR from Escherichia coli. Methods Enzymol (2003) 0.87
A shared mechanism of SoxR activation by redox-cycling compounds. Mol Microbiol (2011) 0.84
Techniques to isolate O2-sensitive proteins: [4Fe-4S]-FNR as an example. Methods Enzymol (2009) 0.82
Evolution of the metabolic and regulatory networks associated with oxygen availability in two phytopathogenic enterobacteria. BMC Genomics (2012) 0.80
Additional determinants within Escherichia coli FNR activating region 1 and RNA polymerase alpha subunit required for transcription activation. J Bacteriol (2005) 0.79
Design principles of a conditional futile cycle exploited for regulation. Mol Biosyst (2015) 0.79
Global approaches for finding small RNA and small open reading frame functions. J Bacteriol (2010) 0.76
Dissecting the role of the N-terminal region of the Escherichia coli global transcription factor FNR. J Bacteriol (2008) 0.76
Transcriptome changes associated with anaerobic growth in Yersinia intermedia (ATCC29909). PLoS One (2013) 0.75
David Ezra Green. Biogr Mem Natl Acad Sci (2004) 0.75