X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 3645509)

Published in Proc Natl Acad Sci U S A on April 17, 2013

Authors

Yvain Nicolet1, Roman Rohac, Lydie Martin, Juan C Fontecilla-Camps

Author Affiliations

1: Metalloproteins Unit, Institut de Biologie Structurale J.-P. Ebel, Commissariat à l'Energie Atomique-Centre National de la Recherche Scientifique-Université Grenoble-Alpes, 38027 Grenoble, France. yvain.nicolet@ibs.fr

Articles citing this

Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers. Chem Rev (2014) 1.13

The iron-sulfur cluster assembly machineries in plants: current knowledge and open questions. Front Plant Sci (2013) 1.13

[FeFe]-hydrogenase maturation: insights into the role HydE plays in dithiomethylamine biosynthesis. Biochemistry (2015) 0.86

The diabetes drug target MitoNEET governs a novel trafficking pathway to rebuild an Fe-S cluster into cytosolic aconitase/iron regulatory protein 1. J Biol Chem (2014) 0.86

Radical S-adenosyl-L-methionine chemistry in the synthesis of hydrogenase and nitrogenase metal cofactors. J Biol Chem (2014) 0.86

Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE. Nat Chem (2016) 0.81

EPR Spectroscopic Studies of [FeFe]-Hydrogenase Maturation. Catal Letters (2015) 0.80

Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics. Biochim Biophys Acta (2015) 0.78

The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium. Sci Adv (2015) 0.77

Mass spectrometric identification of intermediates in the O2-driven [4Fe-4S] to [2Fe-2S] cluster conversion in FNR. Proc Natl Acad Sci U S A (2017) 0.76

Structural and functional characterization of the hydrogenase-maturation HydF protein. Nat Chem Biol (2017) 0.75

Biosynthesis of the [FeFe] Hydrogenase H Cluster: A Central Role for the Radical SAM Enzyme HydG. Inorg Chem (2015) 0.75

Electron Spin Relaxation and Biochemical Characterization of the Hydrogenase Maturase HydF: Insights into [2Fe-2S] and [4Fe-4S] Cluster Communication and Hydrogenase Activation. Biochemistry (2017) 0.75

Articles cited by this

Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01

Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43

Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55

Structure, function, and formation of biological iron-sulfur clusters. Annu Rev Biochem (2005) 6.82

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods. Nucleic Acids Res (2001) 6.49

Structure/function relationships of [NiFe]- and [FeFe]-hydrogenases. Chem Rev (2007) 3.75

Rapid colorimetric micromethod for the quantitation of complexed iron in biological samples. Methods Enzymol (1988) 3.65

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. Science (2006) 2.88

DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen. J Biol Chem (1996) 2.74

A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase. Biochemistry (2008) 2.09

Crystal structure of human iron regulatory protein 1 as cytosolic aconitase. Structure (2006) 2.01

Transfer of sulfur from IscS to IscU during Fe/S cluster assembly. J Biol Chem (2001) 1.96

Contrasting sensitivities of Escherichia coli aconitases A and B to oxidation and iron depletion. J Bacteriol (2003) 1.88

The inactivation of yeast enolase by 2,3-butanedione. Arch Biochem Biophys (1978) 1.79

Sulfur transfer from IscS to IscU: the first step in iron-sulfur cluster biosynthesis. J Am Chem Soc (2001) 1.68

The state of cluster SH and S2- of aconitase during cluster interconversions and removal. A convenient preparation of apoenzyme. J Biol Chem (1988) 1.60

Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima. FEBS Lett (2005) 1.53

Mechanism of oxygen sensing by the bacterial transcription factor fumarate-nitrate reduction (FNR). J Biol Chem (2003) 1.47

Modular organization and identification of a mononuclear iron-binding site within the NifU protein. J Biol Inorg Chem (2000) 1.40

Quantitative assessment of oxygen availability: perceived aerobiosis and its effect on flux distribution in the respiratory chain of Escherichia coli. J Bacteriol (2002) 1.39

(IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer. Angew Chem Int Ed Engl (2012) 1.37

X-ray structure of the [FeFe]-hydrogenase maturase HydE from Thermotoga maritima. J Biol Chem (2008) 1.33

Kinetic analysis of the oxidative conversion of the [4Fe-4S]2+ cluster of FNR to a [2Fe-2S]2+ Cluster. J Bacteriol (2004) 1.31

Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR. Proc Natl Acad Sci U S A (2007) 1.27

AdoMet radical proteins--from structure to evolution--alignment of divergent protein sequences reveals strong secondary structure element conservation. Nucleic Acids Res (2004) 1.24

Iron-sulfur cluster biosynthesis: characterization of iron nucleation sites for assembly of the [2Fe-2S]2+ cluster core in IscU proteins. J Am Chem Soc (2002) 1.10

Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein. Proc Natl Acad Sci U S A (2012) 1.09

Iron-containing transcription factors and their roles as sensors. Curr Opin Chem Biol (2011) 1.07

Surprising cofactors in metalloenzymes. Curr Opin Struct Biol (2003) 1.06

Influence of the environment on the [4Fe-4S]2+ to [2Fe-2S]2+ cluster switch in the transcriptional regulator FNR. J Am Chem Soc (2008) 1.03

Iron-sulfur cluster sensor-regulators. Curr Opin Chem Biol (2012) 1.03

Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S].FNR of Escherichia coli. FEBS J (2005) 0.84

Articles by these authors

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. Science (2006) 2.88

Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products. J Biol Chem (2003) 2.88

Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase. Nat Struct Biol (2003) 2.75

The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J Biol Chem (2003) 2.02

Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein. Structure (2006) 1.90

Structure and activation of the C1 complex of complement: unraveling the puzzle. Trends Immunol (2004) 1.59

X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.57

Structural insights into the innate immune recognition specificities of L- and H-ficolins. EMBO J (2007) 1.53

Structural differences between the ready and unready oxidized states of [NiFe] hydrogenases. J Biol Inorg Chem (2005) 1.47

Visible light-driven H(2) production by hydrogenases attached to dye-sensitized TiO(2) nanoparticles. J Am Chem Soc (2009) 1.41

(IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer. Angew Chem Int Ed Engl (2012) 1.37

Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization. Eur J Biochem (2002) 1.35

Electrochemical definitions of O2 sensitivity and oxidative inactivation in hydrogenases. J Am Chem Soc (2005) 1.33

X-ray structure of the [FeFe]-hydrogenase maturase HydE from Thermotoga maritima. J Biol Chem (2008) 1.33

The role of the maturase HydG in [FeFe]-hydrogenase active site synthesis and assembly. FEBS Lett (2009) 1.26

Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin. J Biol Chem (2009) 1.16

The difference a Se makes? Oxygen-tolerant hydrogen production by the [NiFeSe]-hydrogenase from Desulfomicrobium baculatum. J Am Chem Soc (2008) 1.15

Experimental approaches to kinetics of gas diffusion in hydrogenase. Proc Natl Acad Sci U S A (2008) 1.12

Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins. Proc Natl Acad Sci U S A (2009) 1.12

Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins. J Biol Chem (2008) 1.08

Electrochemical kinetic investigations of the reactions of [FeFe]-hydrogenases with carbon monoxide and oxygen: comparing the importance of gas tunnels and active-site electronic/redox effects. J Am Chem Soc (2009) 1.05

Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch. J Biol Chem (2007) 1.04

Introduction of methionines in the gas channel makes [NiFe] hydrogenase aero-tolerant. J Am Chem Soc (2009) 1.00

Carbon monoxide dehydrogenase reaction mechanism: a likely case of abnormal CO2 insertion to a Ni-H(-) bond. Inorg Chem (2011) 1.00

Electronic states of the O2-tolerant [NiFe] hydrogenase proximal cluster. Proc Natl Acad Sci U S A (2013) 1.00

Principles of sustained enzymatic hydrogen oxidation in the presence of oxygen--the crucial influence of high potential Fe-S clusters in the electron relay of [NiFe]-hydrogenases. J Am Chem Soc (2013) 0.99

Crystal structure of tryptophan lyase (NosL): evidence for radical formation at the amino group of tryptophan. Angew Chem Int Ed Engl (2014) 0.99

A glycyl free radical as the precursor in the synthesis of carbon monoxide and cyanide by the [FeFe]-hydrogenase maturase HydG. FEBS Lett (2010) 0.99

Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate. Structure (2006) 0.98

The structural plasticity of the proximal [4Fe3S] cluster is responsible for the O2 tolerance of membrane-bound [NiFe] hydrogenases. Angew Chem Int Ed Engl (2013) 0.98

How light-harvesting semiconductors can alter the bias of reversible electrocatalysts in favor of H2 production and CO2 reduction. J Am Chem Soc (2013) 0.94

The quest for a functional substrate access tunnel in FeFe hydrogenase. Faraday Discuss (2011) 0.94

Catalytic electrochemistry of a [NiFeSe]-hydrogenase on TiO2 and demonstration of its suitability for visible-light driven H2 production. Chem Commun (Camb) (2008) 0.94

A QM/MM study of proton transport pathways in a [NiFe] hydrogenase. Proteins (2008) 0.93

Structural insights into the recognition properties of human ficolins. J Innate Immun (2009) 0.92

Crystallographic evidence for a CO/CO(2) tunnel gating mechanism in the bifunctional carbon monoxide dehydrogenase/acetyl coenzyme A synthase from Moorella thermoacetica. J Biol Inorg Chem (2004) 0.92

Function of the tunnel in acetylcoenzyme A synthase/carbon monoxide dehydrogenase. J Biol Inorg Chem (2006) 0.92

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response. Cell Res (2013) 0.90

Structure-function relationships in [FeFe]-hydrogenase active site maturation. J Biol Chem (2012) 0.89

DHR51, the Drosophila melanogaster homologue of the human photoreceptor cell-specific nuclear receptor, is a thiolate heme-binding protein. Biochemistry (2008) 0.87

Electrochemical investigations of the interconversions between catalytic and inhibited states of the [FeFe]-hydrogenase from Desulfovibrio desulfuricans. J Am Chem Soc (2006) 0.87

Structural bases for the catalytic mechanism of Ni-containing carbon monoxide dehydrogenases. Dalton Trans (2005) 0.85

Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae. Acta Crystallogr D Biol Crystallogr (2003) 0.84

Crystal structure of HydG from Carboxydothermus hydrogenoformans: a trifunctional [FeFe]-hydrogenase maturase. Chembiochem (2014) 0.83

Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states. J Biol Inorg Chem (2014) 0.83

Structural characterization of a putative endogenous metal chelator in the periplasmic nickel transporter NikA. Biochemistry (2008) 0.83

Crystallographic and spectroscopic evidence for high affinity binding of FeEDTA(H2O)- to the periplasmic nickel transporter NikA. J Am Chem Soc (2005) 0.83

The protein environment drives selectivity for sulfide oxidation by an artificial metalloenzyme. Chembiochem (2009) 0.82

Biochemistry. A natural choice for activating hydrogen. Science (2008) 0.82

Crystallographic snapshots of the reaction of aromatic C-H with O(2) catalysed by a protein-bound iron complex. Nat Chem (2010) 0.82

The possible role of an [FeFe]-hydrogenase-like protein in the plant responses to changing atmospheric oxygen levels. J Inorg Biochem (2008) 0.82

Crystal structure and functional studies of an unusual L-cysteine desulfurase from Archaeoglobus fulgidus. Dalton Trans (2012) 0.81

The crystal structure of Fe₄S₄ quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad. J Am Chem Soc (2014) 0.80

Density functional calculations for modeling the active site of nickel-iron hydrogenases. 2. Predictions for the unready and ready States and the corresponding activation processes. Inorg Chem (2002) 0.79

Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica. Biochemistry (2009) 0.79

Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase. Chembiochem (2003) 0.79

Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5. J Innate Immun (2014) 0.79

Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5: conformational analysis, dimerisation and consequences for receptor activation. Chembiochem (2014) 0.78

The binding mode of Ni-(L-His)2 in NikA revealed by X-ray crystallography. J Inorg Biochem (2012) 0.78

Formaldehyde--a rapid and reversible inhibitor of hydrogen production by [FeFe]-hydrogenases. J Am Chem Soc (2011) 0.77

[NiFe]-hydrogenases revisited: nickel-carboxamido bond formation in a variant with accrued O2-tolerance and a tentative re-interpretation of Ni-SI states. Metallomics (2015) 0.77

The enamine intermediate may not be universal to thiamine catalysis. Angew Chem Int Ed Engl (2007) 0.76

The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin. PLoS One (2013) 0.76

Histidine 416 of the periplasmic binding protein NikA is essential for nickel uptake in Escherichia coli. FEBS Lett (2011) 0.76

The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design. J Biol Inorg Chem (2012) 0.75

The enamine intermediate may not be universal to thiamine catalysis. Angew Chem Int Ed Engl (2008) 0.75

Artificial metalloenzymes derived from bovine β-lactoglobulin for the asymmetric transfer hydrogenation of an aryl ketone--synthesis, characterization and catalytic activity. Dalton Trans (2014) 0.75