Published in J Neurosci on November 17, 2004
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol (2010) 2.40
A single vesicular glutamate transporter is sufficient to fill a synaptic vesicle. Neuron (2006) 2.09
Rab3 dynamically controls protein composition at active zones. Neuron (2009) 2.07
Vesicular glutamate transport at a central synapse limits the acuity of visual perception in zebrafish. Neuron (2007) 1.96
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci (2005) 1.68
Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo. Proc Natl Acad Sci U S A (2014) 1.63
The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60
Single-cell mapping of neural and glial gene expression in the developing Drosophila CNS midline cells. Dev Biol (2006) 1.40
DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth. Neural Dev (2007) 1.40
A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles. Nat Neurosci (2009) 1.39
A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. J Cell Biol (2010) 1.33
Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. PLoS One (2008) 1.27
Unc-51 controls active zone density and protein composition by downregulating ERK signaling. J Neurosci (2009) 1.19
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J Cell Biol (2010) 1.13
Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin. Genetics (2008) 1.09
Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia. Biol Psychiatry (2007) 1.09
Synaptic vesicle protein trafficking at the glutamate synapse. Neuroscience (2008) 1.06
Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3. Proc Natl Acad Sci U S A (2006) 1.06
A glial amino-acid transporter controls synapse strength and courtship in Drosophila. Nat Neurosci (2007) 1.06
Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model. PLoS Genet (2012) 1.05
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. J Neurosci (2009) 1.04
Genetic inactivation of the vesicular glutamate transporter 2 (VGLUT2) in the mouse: what have we learnt about functional glutamatergic neurotransmission? Ups J Med Sci (2010) 1.03
Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration. Neurobiol Dis (2010) 1.03
Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron (2009) 1.02
Effects of chronic unpredictable stress and methamphetamine on hippocampal glutamate function. Brain Res (2007) 1.02
Normal dendrite growth in Drosophila motor neurons requires the AP-1 transcription factor. Dev Neurobiol (2008) 1.01
Dual regulation of Ca2+-dependent glutamate release from astrocytes: vesicular glutamate transporters and cytosolic glutamate levels. Glia (2009) 1.01
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet (2009) 1.00
Trafficking of vesicular neurotransmitter transporters. Traffic (2008) 0.99
Candidate glutamatergic neurons in the visual system of Drosophila. PLoS One (2011) 0.98
Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection. J Exp Biol (2010) 0.98
Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila. J Neurosci (2013) 0.97
Altered expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in Parkinson disease. Neurobiol Aging (2006) 0.97
Presynaptic calcium channel localization and calcium-dependent synaptic vesicle exocytosis regulated by the Fuseless protein. J Neurosci (2008) 0.97
Homeostatic plasticity at the Drosophila neuromuscular junction. Neuropharmacology (2013) 0.97
Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog. J Neurosci (2010) 0.96
Dynamics of glutamatergic signaling in the mushroom body of young adult Drosophila. Neural Dev (2010) 0.95
Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Hum Mol Genet (2014) 0.95
PP2A and GSK-3beta act antagonistically to regulate active zone development. J Neurosci (2009) 0.94
The wiring diagram of a glomerular olfactory system. Elife (2016) 0.94
FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption. J Cell Biol (2012) 0.93
Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production. Elife (2014) 0.92
Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster. Dev Biol (2008) 0.92
The role of ubiquitin-mediated pathways in regulating synaptic development, axonal degeneration and regeneration: insights from fly and worm. J Physiol (2013) 0.91
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling. J Neurosci (2013) 0.91
Identification of endophilins 1 and 3 as selective binding partners for VGLUT1 and their co-localization in neocortical glutamatergic synapses: implications for vesicular glutamate transporter trafficking and excitatory vesicle formation. Cell Mol Neurobiol (2006) 0.91
dbx mediates neuronal specification and differentiation through cross-repressive, lineage-specific interactions with eve and hb9. Development (2009) 0.90
Identification and analysis of a glutamatergic local interneuron lineage in the adult Drosophila olfactory system. Neural Syst Circuits (2011) 0.89
The Drosophila blood-brain barrier: development and function of a glial endothelium. Front Neurosci (2014) 0.89
Acoustic overexposure increases the expression of VGLUT-2 mediated projections from the lateral vestibular nucleus to the dorsal cochlear nucleus. PLoS One (2012) 0.88
New approaches for studying synaptic development, function, and plasticity using Drosophila as a model system. J Neurosci (2013) 0.88
The DISABLED protein functions in CLATHRIN-mediated synaptic vesicle endocytosis and exoendocytic coupling at the active zone. Proc Natl Acad Sci U S A (2011) 0.87
Drosophila Syd-1, liprin-α, and protein phosphatase 2A B' subunit Wrd function in a linear pathway to prevent ectopic accumulation of synaptic materials in distal axons. J Neurosci (2014) 0.87
Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease. Hum Mol Genet (2012) 0.87
SkpA restrains synaptic terminal growth during development and promotes axonal degeneration following injury. J Neurosci (2014) 0.87
Stoned B mediates sorting of integral synaptic vesicle proteins. Neuroscience (2008) 0.86
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci (2013) 0.86
The atypical cadherin flamingo regulates synaptogenesis and helps prevent axonal and synaptic degeneration in Drosophila. Mol Cell Neurosci (2007) 0.86
Constraints, independence, and evolution of thermal plasticity: probing genetic architecture of long- and short-term thermal acclimation. Proc Natl Acad Sci U S A (2015) 0.86
Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophr Res (2013) 0.86
Optogenetic acidification of synaptic vesicles and lysosomes. Nat Neurosci (2015) 0.85
Drosophila melanogaster as a genetic model system to study neurotransmitter transporters. Neurochem Int (2014) 0.85
Analysis of synaptic growth and function in Drosophila with an extended larval stage. J Neurosci (2012) 0.85
A putative vesicular transporter expressed in Drosophila mushroom bodies that mediates sexual behavior may define a neurotransmitter system. Neuron (2011) 0.85
Molecular mechanisms driving homeostatic plasticity of neurotransmitter release. Front Cell Neurosci (2013) 0.85
VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review. ISRN Neurol (2013) 0.85
Adar is essential for optimal presynaptic function. Mol Cell Neurosci (2012) 0.85
Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum. J Comp Neurol (2011) 0.84
Na(+) /H(+) exchange via the Drosophila vesicular glutamate transporter mediates activity-induced acid efflux from presynaptic terminals. J Physiol (2016) 0.84
Cholesterol and F-actin are required for clustering of recycling synaptic vesicle proteins in the presynaptic plasma membrane. J Physiol (2013) 0.84
NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. PLoS Biol (2013) 0.84
Homeostatic synaptic depression is achieved through a regulated decrease in presynaptic calcium channel abundance. Elife (2015) 0.83
Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons. Front Cell Neurosci (2014) 0.82
N-glycosylation requirements in neuromuscular synaptogenesis. Development (2013) 0.82
Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning. J Neurosci (2012) 0.82
Reduced expression of the vesicular acetylcholine transporter and neurotransmitter content affects synaptic vesicle distribution and shape in mouse neuromuscular junction. PLoS One (2013) 0.81
VGLUT3 does not synergize GABA/glycine release during functional refinement of an inhibitory auditory circuit. Front Neural Circuits (2014) 0.81
Insulin/IGF-regulated size scaling of neuroendocrine cells expressing the bHLH transcription factor Dimmed in Drosophila. PLoS Genet (2013) 0.81
Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin. Mol Biol Cell (2013) 0.81
Estradiol negative feedback regulation by glutamatergic afferents to A15 dopaminergic neurons: variation with season. Endocrinology (2009) 0.81
Neuronal Glud1 (glutamate dehydrogenase 1) over-expressing mice: increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression. Neurochem Int (2011) 0.81
The complete connectome of a learning and memory centre in an insect brain. Nature (2017) 0.81
Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum. J Comp Neurol (2014) 0.80
BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission. J Cell Sci (2015) 0.80
A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo. J Biol Chem (2010) 0.80
Drosophila neuroligin 1 regulates synaptic growth and function in response to activity and phosphoinositide-3-kinase. Mol Cell Neurosci (2012) 0.79
AP180 couples protein retrieval to clathrin-mediated endocytosis of synaptic vesicles. Traffic (2014) 0.79
Functional Characterization of a Vesicular Glutamate Transporter in an Interneuron That Makes Excitatory and Inhibitory Synaptic Connections in a Molluscan Neural Circuit. J Neurosci (2015) 0.78
Developmental up-regulation of vesicular glutamate transporter-1 promotes neocortical presynaptic terminal development. PLoS One (2012) 0.78
Distribution of vesicular glutamate transporters in the human brain. Front Neuroanat (2015) 0.78
ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. Nat Commun (2016) 0.78
FlpStop, a tool for conditional gene control in Drosophila. Elife (2017) 0.78
Drosophila larval to pupal switch under nutrient stress requires IP3R/Ca(2+) signalling in glutamatergic interneurons. Elife (2016) 0.77
l(2)01810 is a novel type of glutamate transporter that is responsible for megamitochondrial formation. Biochem J (2011) 0.77
SNARE-dependent glutamate release in megakaryocytes. Exp Hematol (2010) 0.77
The Drosophila KIF1A Homolog unc-104 Is Important for Site-Specific Synapse Maturation. Front Cell Neurosci (2016) 0.76
BMP signaling and microtubule organization regulate synaptic strength. Neuroscience (2015) 0.76
Expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in the rat dental pulp and trigeminal ganglion following inflammation. PLoS One (2014) 0.76
Presynaptic Molecular Determinants of Quantal Size. Front Synaptic Neurosci (2016) 0.75
Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron (2006) 3.17
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron (2009) 3.11
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron (2012) 2.88
Synaptic development: insights from Drosophila. Curr Opin Neurobiol (2007) 2.67
Differential localization of glutamate receptor subunits at the Drosophila neuromuscular junction. J Neurosci (2004) 2.43
A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration. Nat Neurosci (2009) 2.42
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury. J Cell Biol (2010) 2.40
Control of a kinesin-cargo linkage mechanism by JNK pathway kinases. Curr Biol (2007) 2.33
Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. J Neurosci (2005) 2.30
A single vesicular glutamate transporter is sufficient to fill a synaptic vesicle. Neuron (2006) 2.09
Rab3 dynamically controls protein composition at active zones. Neuron (2009) 2.07
The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev (2007) 1.85
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons. Nat Neurosci (2011) 1.66
The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60
Visualizing glutamatergic cell bodies and synapses in Drosophila larval and adult CNS. J Comp Neurol (2008) 1.54
Bimodal control of dendritic and axonal growth by the dual leucine zipper kinase pathway. PLoS Biol (2013) 1.51
Preferential localization of glutamate receptors opposite sites of high presynaptic release. Curr Biol (2004) 1.46
A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci (2007) 1.40
DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth. Neural Dev (2007) 1.40
The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Cell Rep (2013) 1.39
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation. Nat Chem Biol (2012) 1.37
Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway. J Neurosci (2010) 1.37
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proc Natl Acad Sci U S A (2013) 1.36
Sarm1-mediated axon degeneration requires both SAM and TIR interactions. J Neurosci (2013) 1.32
The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol Dis (2010) 1.31
Ubiquitin and the synapse. Nat Rev Neurosci (2002) 1.29
A conditioning lesion protects axons from degeneration via the Wallenda/DLK MAP kinase signaling cascade. J Neurosci (2012) 1.26
Postfusional control of quantal current shape. Neuron (2004) 1.26
SCG10 is a JNK target in the axonal degeneration pathway. Proc Natl Acad Sci U S A (2012) 1.16
Epidural hematomas after removal of percutaneous spinal cord stimulator trial leads: two case reports. Reg Anesth Pain Med (2013) 1.14
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J Cell Biol (2010) 1.13
A splice variant of the Drosophila vesicular monoamine transporter contains a conserved trafficking domain and functions in the storage of dopamine, serotonin, and octopamine. J Neurobiol (2005) 1.13
Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin. Genetics (2008) 1.09
Differential decline in behavioral performance of Drosophila melanogaster with age. Mech Ageing Dev (2006) 1.08
Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan. Aging Cell (2010) 1.08
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. J Neurosci (2012) 1.05
Synaptic defects in a Drosophila model of congenital muscular dystrophy. J Neurosci (2008) 1.05
Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration. Neurobiol Dis (2010) 1.03
Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Proc Natl Acad Sci U S A (2002) 1.02
The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction. J Neurosci (2006) 1.01
A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet (2008) 1.01
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet (2009) 1.00
RIM promotes calcium channel accumulation at active zones of the Drosophila neuromuscular junction. J Neurosci (2012) 1.00
Trafficking of vesicular neurotransmitter transporters. Traffic (2008) 0.99
Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection. J Exp Biol (2010) 0.98
Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila. J Neurosci (2013) 0.97
Highwire regulates guidance of sister axons in the Drosophila mushroom body. J Neurosci (2011) 0.96
Phr1 regulates retinogeniculate targeting independent of activity and ephrin-A signalling. Mol Cell Neurosci (2009) 0.96
PP2A and GSK-3beta act antagonistically to regulate active zone development. J Neurosci (2009) 0.94
The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5). Traffic (2006) 0.94
SLC18: Vesicular neurotransmitter transporters for monoamines and acetylcholine. Mol Aspects Med (2013) 0.93
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling. J Neurosci (2013) 0.91
Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function. Proc Natl Acad Sci U S A (2012) 0.90
Membrane topology of the Drosophila vesicular glutamate transporter. J Neurochem (2007) 0.89
Stathmin is required for stability of the Drosophila neuromuscular junction. J Neurosci (2011) 0.89
Dispensable, redundant, complementary, and cooperative roles of dopamine, octopamine, and serotonin in Drosophila melanogaster. Genetics (2012) 0.88
New approaches for studying synaptic development, function, and plasticity using Drosophila as a model system. J Neurosci (2013) 0.88
Sodium and potassium currents influence Wallerian degeneration of injured Drosophila axons. J Neurosci (2013) 0.88
The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance. J Neurosci (2011) 0.87
A screen for neurotransmitter transporters expressed in the visual system of Drosophila melanogaster identifies three novel genes. Dev Neurobiol (2007) 0.87
A large-scale RNAi screen identifies functional classes of genes shaping synaptic development and maintenance. Dev Biol (2012) 0.85
A putative vesicular transporter expressed in Drosophila mushroom bodies that mediates sexual behavior may define a neurotransmitter system. Neuron (2011) 0.85
The appropriate use of neurostimulation: avoidance and treatment of complications of neurostimulation therapies for the treatment of chronic pain. Neuromodulation Appropriateness Consensus Committee. Neuromodulation (2014) 0.84
The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains. J Biol Chem (2012) 0.84
Investigating the safety factor at an invertebrate neuromuscular junction. J Neurobiol (2005) 0.82
Rhythms and blues: modulation of oscillatory synchrony and the mechanism of action of antidepressant treatments. Ann N Y Acad Sci (2015) 0.80
A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo. J Biol Chem (2010) 0.80
Transport of polyamines in Drosophila S2 cells: kinetics, pharmacology and dependence on the plasma membrane proton gradient. Biochem J (2006) 0.79
Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol (2013) 0.79
A role for the membrane Golgi protein Ema in autophagy. Autophagy (2012) 0.79
Coordinating synaptic growth without being a nervous wreck. Neuron (2004) 0.78
EGFR signaling modulates synaptic connectivity via Gurken. Dev Neurobiol (2012) 0.76
Road rage and fruit flies. Nat Genet (2007) 0.75
Fast flies take a quantum leap. Neuron (2006) 0.75
Identification of potential mediators of retinotopic mapping: a comparative proteomic analysis of optic nerve from WT and Phr1 retinal knockout mice. J Proteome Res (2012) 0.75
Vesicular neurotransmitter transporter trafficking in vivo: moving from cells to flies. Fly (Austin) (2010) 0.75