Published in J Neurosci on November 21, 2012
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife (2015) 1.50
RIM controls homeostatic plasticity through modulation of the readily-releasable vesicle pool. J Neurosci (2012) 1.24
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Homeostatic plasticity at the Drosophila neuromuscular junction. Neuropharmacology (2013) 0.97
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Presynaptic ultrastructural plasticity along CA3→CA1 axons during long-term potentiation in mature hippocampus. J Comp Neurol (2013) 0.87
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Prion protein facilitates synaptic vesicle release by enhancing release probability. Hum Mol Genet (2014) 0.79
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Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release. J Cell Biol (2016) 0.76
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Studying synaptic efficiency by post-hoc immunolabelling. BMC Neurosci (2013) 0.75
A novel region in the CaV2.1 α1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone. Elife (2017) 0.75
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Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons. J Neurosci (2017) 0.75
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RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature (2002) 4.37
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A post-docking role for active zone protein Rim. Nat Neurosci (2001) 3.40
RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell (2011) 2.90
Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming. Neuron (2001) 2.49
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Maturation of active zone assembly by Drosophila Bruchpilot. J Cell Biol (2009) 2.34
RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone. Neuron (2011) 2.29
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Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J Biol Chem (2001) 1.86
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J (2005) 1.86
RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels. Neuron (2002) 1.81
Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system. J Neurochem (1994) 1.76
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1. J Cell Biol (2002) 1.65
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones. Proc Natl Acad Sci U S A (2002) 1.62
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. Science (2011) 1.59
Active zone localization of presynaptic calcium channels encoded by the cacophony locus of Drosophila. J Neurosci (2004) 1.55
Visualizing glutamatergic cell bodies and synapses in Drosophila larval and adult CNS. J Comp Neurol (2008) 1.54
Preferential localization of glutamate receptors opposite sites of high presynaptic release. Curr Biol (2004) 1.46
Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons. Nat Neurosci (2011) 1.34
Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins. Genomics (2003) 1.27
Vectors for the expression of tagged proteins in Drosophila. Biotechniques (2001) 1.27
Lack of synapsin I reduces the readily releasable pool of synaptic vesicles at central inhibitory synapses. J Neurosci (2007) 1.25
Rapid active zone remodeling during synaptic plasticity. J Neurosci (2011) 1.24
Structural and functional plasticity of the cytoplasmic active zone. Curr Opin Neurobiol (2010) 1.17
Molecular organization and assembly of the presynaptic active zone of neurotransmitter release. Results Probl Cell Differ (2006) 1.07
Redundant localization mechanisms of RIM and ELKS in Caenorhabditis elegans. J Neurosci (2005) 1.03
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell (2002) 3.21
Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron (2006) 3.17
Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron (2009) 3.15
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron (2012) 2.88
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MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. J Biol Chem (2010) 2.49
Differential localization of glutamate receptor subunits at the Drosophila neuromuscular junction. J Neurosci (2004) 2.43
A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration. Nat Neurosci (2009) 2.42
Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. J Neurosci (2005) 2.30
Increased expression of the Drosophila vesicular glutamate transporter leads to excess glutamate release and a compensatory decrease in quantal content. J Neurosci (2004) 2.30
Association between vitamin D and risk of colorectal cancer: a systematic review of prospective studies. J Clin Oncol (2011) 2.24
Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. Clin Cancer Res (2004) 2.13
No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis of 21 studies involving 24,063 subjects. Breast Cancer Res Treat (2010) 2.12
A single vesicular glutamate transporter is sufficient to fill a synaptic vesicle. Neuron (2006) 2.09
Rab3 dynamically controls protein composition at active zones. Neuron (2009) 2.07
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. Nat Genet (2011) 2.05
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat Genet (2012) 2.00
The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev (2007) 1.85
Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene (2004) 1.77
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology (2005) 1.67
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons. Nat Neurosci (2011) 1.66
S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE). PLoS One (2011) 1.63
The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation. Curr Biol (2004) 1.60
The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60
The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res (2005) 1.56
Visualizing glutamatergic cell bodies and synapses in Drosophila larval and adult CNS. J Comp Neurol (2008) 1.54
Candidate microRNA biomarkers in human colorectal cancer: systematic review profiling studies and experimental validation. Int J Cancer (2011) 1.46
Preferential localization of glutamate receptors opposite sites of high presynaptic release. Curr Biol (2004) 1.46
Lack of association between HER2 codon 655 polymorphism and breast cancer susceptibility: meta-analysis of 22 studies involving 19,341 subjects. Breast Cancer Res Treat (2010) 1.43
DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth. Neural Dev (2007) 1.40
The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Cell Rep (2013) 1.39
A new intertype recombinant between genotypes C and D of hepatitis B virus identified in China. J Gen Virol (2005) 1.38
Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway. J Neurosci (2010) 1.37
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proc Natl Acad Sci U S A (2013) 1.36
A robust and accurate binning algorithm for metagenomic sequences with arbitrary species abundance ratio. Bioinformatics (2011) 1.34
Sarm1-mediated axon degeneration requires both SAM and TIR interactions. J Neurosci (2013) 1.32
Ubiquitin and the synapse. Nat Rev Neurosci (2002) 1.29
Postfusional control of quantal current shape. Neuron (2004) 1.26
Stomatin-like protein 2 is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma. Clin Cancer Res (2006) 1.19
Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering. J Am Chem Soc (2012) 1.16
Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. Mol Cell Biol (2005) 1.16
SCG10 is a JNK target in the axonal degeneration pathway. Proc Natl Acad Sci U S A (2012) 1.16
Role for Kruppel-like factor 4 in determining the outcome of p53 response to DNA damage. Cancer Res (2009) 1.16
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J Cell Biol (2010) 1.13
XIAP is highly expressed in esophageal cancer and its downregulation by RNAi sensitizes esophageal carcinoma cell lines to chemotherapeutics. Cancer Biol Ther (2007) 1.11
The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma. Int J Cancer (2003) 1.06
Differential expression of S100 gene family in human esophageal squamous cell carcinoma. J Cancer Res Clin Oncol (2004) 1.06
Synthesis of Anti-beta-substituted gamma,delta-unsaturated amino acids via Eschenmoser-Claisen rearrangement. Org Lett (2006) 1.05
Three-tiered role of the pioneer factor GATA2 in promoting androgen-dependent gene expression in prostate cancer. Nucleic Acids Res (2014) 1.05
Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulation. J Biol Chem (2012) 1.05
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. J Neurosci (2012) 1.05
Synaptic defects in a Drosophila model of congenital muscular dystrophy. J Neurosci (2008) 1.05
Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by beta-catenin /TCF pathway in human esophageal squamous cell carcinoma. Int J Cancer (2005) 1.04
Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration. Neurobiol Dis (2010) 1.03
Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Proc Natl Acad Sci U S A (2002) 1.02
Overexpression of stefin A in human esophageal squamous cell carcinoma cells inhibits tumor cell growth, angiogenesis, invasion, and metastasis. Clin Cancer Res (2005) 1.02
The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction. J Neurosci (2006) 1.01
B23 regulates GADD45a nuclear translocation and contributes to GADD45a-induced cell cycle G2-M arrest. J Biol Chem (2005) 1.01
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet (2009) 1.00
Differential role of 14-3-3 family members in Xenopus development. Dev Dyn (2006) 1.00
Reduced MTA1 expression by RNAi inhibits in vitro invasion and migration of esophageal squamous cell carcinoma cell line. Clin Exp Metastasis (2006) 1.00
Streamlined expressed protein ligation using split inteins. J Am Chem Soc (2012) 0.99
Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan-induced diabetic rats. Phytother Res (2009) 0.99
High-level SLP-2 expression and HER-2/neu protein expression are associated with decreased breast cancer patient survival. Am J Clin Pathol (2007) 0.98
Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila. J Neurosci (2013) 0.97
Phr1 regulates retinogeniculate targeting independent of activity and ephrin-A signalling. Mol Cell Neurosci (2009) 0.96
Highwire regulates guidance of sister axons in the Drosophila mushroom body. J Neurosci (2011) 0.96
A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway. Biochem J (2009) 0.96
Comparing fuel reduction treatments for reducing wildfire size and intensity in a boreal forest landscape of northeastern China. Sci Total Environ (2013) 0.96
A novel gene, NMES1, downregulated in human esophageal squamous cell carcinoma. Int J Cancer (2002) 0.95
Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents. Cancer Biol Ther (2009) 0.95
S100A14, a member of the EF-hand calcium-binding proteins, is overexpressed in breast cancer and acts as a modulator of HER2 signaling. J Biol Chem (2013) 0.95
PP2A and GSK-3beta act antagonistically to regulate active zone development. J Neurosci (2009) 0.94
Drosophila sec10 is required for hormone secretion but not general exocytosis or neurotransmission. Traffic (2002) 0.94
Distinct presynaptic and postsynaptic dismantling processes of Drosophila neuromuscular junctions during metamorphosis. J Neurosci (2010) 0.94
Asymmetric Eschenmoser-Claisen rearrangement for anti-beta-substituted gamma,delta-unsaturated amino acids. Org Lett (2007) 0.94
The initial evaluation of non-peptidic small-molecule HDM2 inhibitors based on p53-HDM2 complex structure. Cancer Lett (2002) 0.94
Reelin is involved in transforming growth factor-β1-induced cell migration in esophageal carcinoma cells. PLoS One (2012) 0.94
CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma. Cancer Lett (2002) 0.93
Migfilin regulates esophageal cancer cell motility through promoting GSK-3β-mediated degradation of β-catenin. Mol Cancer Res (2012) 0.93
Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly. PLoS Genet (2013) 0.93
NetCAD: a network analysis tool for coronary artery disease-associated PPI network. Bioinformatics (2012) 0.93
Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. Int J Cancer (2007) 0.93
NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity. J Neurophysiol (2008) 0.93
Stomatin-like protein 2 is overexpressed and related to cell growth in human endometrial adenocarcinoma. Oncol Rep (2007) 0.93
Mutational analysis establishes a critical role for the N terminus of fragile X mental retardation protein FMRP. J Neurosci (2008) 0.93
A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B. J Pharmacol Exp Ther (2003) 0.92
Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria. Hum Mol Genet (2010) 0.92
HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila. Proc Natl Acad Sci U S A (2013) 0.92
Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma. Cancer Res (2009) 0.92
Peroxisome proliferator-activated receptor γ agonists induce cell cycle arrest through transcriptional regulation of Kruppel-like factor 4 (KLF4). J Biol Chem (2012) 0.92
The role of ubiquitin-mediated pathways in regulating synaptic development, axonal degeneration and regeneration: insights from fly and worm. J Physiol (2013) 0.91
CGAP: a new comprehensive platform for the comparative analysis of chloroplast genomes. BMC Bioinformatics (2013) 0.91