Published in J Neurosci on November 17, 2004
RACK1, A multifaceted scaffolding protein: Structure and function. Cell Commun Signal (2011) 2.16
Brain-derived neurotrophic factor and cocaine addiction. Brain Res (2009) 1.76
Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. J Neurosci (2009) 1.62
Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum. Biol Psychiatry (2012) 1.61
Neuroscience of alcoholism: molecular and cellular mechanisms. Cell Mol Life Sci (2009) 1.32
Role of BDNF and GDNF in drug reward and relapse: a review. Neurosci Biobehav Rev (2009) 1.31
Signaling pathways mediating alcohol effects. Curr Top Behav Neurosci (2013) 1.20
Escalating ethanol intake is associated with altered corticostriatal BDNF expression. J Neurochem (2009) 1.13
Acute ethanol modulates glutamatergic and serotonergic phase shifts of the mouse circadian clock in vitro. Neuroscience (2008) 1.12
Chromatin remodeling--a novel strategy to control excessive alcohol drinking. Transl Psychiatry (2013) 1.11
microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking. J Neurosci (2014) 1.11
The role of amygdaloid brain-derived neurotrophic factor, activity-regulated cytoskeleton-associated protein and dendritic spines in anxiety and alcoholism. Addict Biol (2010) 1.10
Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis. Neurosci Biobehav Rev (2013) 1.10
Genomic analysis of individual differences in ethanol drinking: evidence for non-genetic factors in C57BL/6 mice. PLoS One (2011) 1.08
GDNF--a potential target to treat addiction. Pharmacol Ther (2008) 1.07
Ethanol-BDNF interactions: still more questions than answers. Pharmacol Ther (2008) 1.06
Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice. Addict Biol (2011) 1.05
Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence. Pharmacogenomics J (2012) 1.02
GDNF is an endogenous negative regulator of ethanol-mediated reward and of ethanol consumption after a period of abstinence. Alcohol Clin Exp Res (2009) 1.02
TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology (2010) 1.01
Nucleotide sequence variation within the human tyrosine kinase B neurotrophin receptor gene: association with antisocial alcohol dependence. Pharmacogenomics J (2007) 1.00
Epigenetic regulation of BDNF expression via the scaffolding protein RACK1. J Biol Chem (2010) 0.99
RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency. Cell Mol Life Sci (2012) 0.95
MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption. Mol Psychiatry (2014) 0.95
Brain-derived neurotrophic factor-estrogen interactions in the hippocampal mossy fiber pathway: implications for normal brain function and disease. Neuroscience (2012) 0.94
Alcohol induced depressive-like behavior is associated with a reduction in hippocampal BDNF. Pharmacol Biochem Behav (2011) 0.94
BDNF-mediated regulation of ethanol consumption requires the activation of the MAP kinase pathway and protein synthesis. Eur J Neurosci (2012) 0.93
Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward. J Neurosci (2011) 0.90
The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors. J Neurosci (2012) 0.90
Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcohol Clin Exp Res (2006) 0.90
Corticostriatal BDNF and alcohol addiction. Brain Res (2015) 0.89
Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription. J Biol Chem (2011) 0.88
The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice That Is Reversed by Tropomyosin Receptor Kinase B Activation. Biol Psychiatry (2015) 0.87
Chronic ethanol exposure produces time- and brain region-dependent changes in gene coexpression networks. PLoS One (2015) 0.87
Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. Alcohol Clin Exp Res (2013) 0.86
Alcoholism and diabetes mellitus. Diabetes Metab J (2012) 0.86
Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation. Mol Cancer (2008) 0.85
Ethanol neurotoxicity in the developing cerebellum: underlying mechanisms and implications. Brain Sci (2013) 0.85
Biological studies on alcohol-induced neuronal damage. Psychiatry Investig (2008) 0.85
Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell. Brain Res (2014) 0.84
Molecular mechanisms underlying alcohol-drinking behaviours. Nat Rev Neurosci (2016) 0.83
Long-term effects of peripubertal binge EtOH exposure on hippocampal microRNA expression in the rat. PLoS One (2014) 0.83
Nicotine dependence and serum BDNF levels in male patients with schizophrenia. Psychopharmacology (Berl) (2010) 0.82
Alcohol dependence-induced regulation of the proliferation and survival of adult brain progenitors is associated with altered BDNF-TrkB signaling. Brain Struct Funct (2015) 0.82
Stress, epigenetics, and alcoholism. Alcohol Res (2012) 0.82
Sign-tracking to an appetitive cue predicts incubation of conditioned fear in rats. Behav Brain Res (2014) 0.82
Serum and plasma brain-derived neurotrophic factor (BDNF) in abstinent alcoholics and social drinkers. Alcohol (2012) 0.82
Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol. Alcohol Res Health (2008) 0.82
The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease. Front Synaptic Neurosci (2014) 0.81
Voluntary exercise decreases ethanol preference and consumption in C57BL/6 adolescent mice: sex differences and hippocampal BDNF expression. Physiol Behav (2014) 0.81
Advances in genetic studies of substance abuse in China. Shanghai Arch Psychiatry (2013) 0.81
Opposite effects of acute ethanol exposure on GAP-43 and BDNF expression in the hippocampus versus the cerebellum of juvenile rats. Alcohol (2011) 0.80
Ethanol-induced increases in extracellular dopamine are blunted in brain-derived neurotrophic factor heterozygous mice. Neurosci Lett (2010) 0.80
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone. Neuropsychopharmacology (2014) 0.80
Effects of cigarette smoking and alcohol use on neurocognition and BDNF levels in a Chinese population. Psychopharmacology (Berl) (2015) 0.80
Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking. Brain Res (2014) 0.79
Deletion of Prkcz increases intermittent ethanol consumption in mice. Alcohol Clin Exp Res (2013) 0.79
GDNF is a novel ethanol-responsive gene in the VTA: implications for the development and persistence of excessive drinking. Addict Biol (2013) 0.79
Adolescent Alcohol Exposure: Burden of Epigenetic Reprogramming, Synaptic Remodeling, and Adult Psychopathology. Front Neurosci (2016) 0.77
Juvenile Traumatic Brain Injury Increases Alcohol Consumption and Reward in Female Mice. J Neurotrauma (2015) 0.77
Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors. Alcohol Clin Exp Res (2016) 0.77
Neurotrophins in the ventral tegmental area: Role in social stress, mood disorders and drug abuse. Neuroscience (2014) 0.76
Short-term ethanol exposure causes imbalanced neurotrophic factor allocation in the basal forebrain cholinergic system: a novel insight into understanding the initial processes of alcohol addiction. J Neural Transm (Vienna) (2013) 0.76
Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expression. Neuropharmacology (2016) 0.75
Serum NPY and BNDF response to a behavioral stressor in alcohol-dependent and healthy control participants. Psychopharmacology (Berl) (2011) 0.75
Alcohol, Brain Derived Neurotrophic Factor and Obesity among People Living with HIV. J AIDS Clin Res (2013) 0.75
Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence. Braz J Med Biol Res (2015) 0.75
The Neurotrophic Factor Receptor p75 in the Rat Dorsolateral Striatum Drives Excessive Alcohol Drinking. J Neurosci (2016) 0.75
The BDNF Val66Met polymorphism enhances glutamatergic transmission but diminishes activity-dependent synaptic plasticity in the dorsolateral striatum. Neuropharmacology (2016) 0.75
Effects of Ethanol on the Expression Level of Various BDNF mRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats. Int J Mol Sci (2015) 0.75
Mood Disorders and BDNF Relationship with Alcohol Drinking Trajectories among PLWH Receiving Care. J Alcohol Drug Depend (2014) 0.75
Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial. Neuropsychopharmacology (2017) 0.75
Contingent and non-contingent recreational-like exposure to ethanol alters BDNF expression and signaling in the cortico-accumbal network differently. Psychopharmacology (Berl) (2016) 0.75
Viral-mediated overexpression of the Myelin Transcription Factor 1 (MyT1) in the dentate gyrus attenuates anxiety- and ethanol-related behaviors in rats. Psychopharmacology (Berl) (2017) 0.75
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron (2011) 3.49
Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. Neuron (2003) 2.81
A causal link between prediction errors, dopamine neurons and learning. Nat Neurosci (2013) 2.68
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol (2009) 2.63
Rapid strengthening of thalamo-amygdala synapses mediates cue-reward learning. Nature (2008) 2.47
RACK1, A multifaceted scaffolding protein: Structure and function. Cell Commun Signal (2011) 2.16
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med (2011) 2.10
General and outcome-specific forms of Pavlovian-instrumental transfer: the effect of shifts in motivational state and inactivation of the ventral tegmental area. Eur J Neurosci (2007) 1.89
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders. Proc Natl Acad Sci U S A (2010) 1.88
Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake. FASEB J (2008) 1.87
A developmental switch of AMPA receptor subunits in neocortical pyramidal neurons. J Neurosci (2002) 1.86
Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior. J Neurosci (2007) 1.72
Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. J Neurosci (2012) 1.65
Cocaine enhances NMDA receptor-mediated currents in ventral tegmental area cells via dopamine D5 receptor-dependent redistribution of NMDA receptors. J Neurosci (2006) 1.63
Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. J Neurosci (2009) 1.62
Habitual alcohol seeking: time course and the contribution of subregions of the dorsal striatum. Biol Psychiatry (2012) 1.61
NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1. Proc Natl Acad Sci U S A (2002) 1.59
Context is a trigger for relapse to alcohol. Behav Brain Res (2005) 1.58
Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol (2011) 1.58
Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proc Natl Acad Sci U S A (2005) 1.55
The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism. Mol Pharmacol (2004) 1.50
Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse. J Neurosci (2010) 1.46
Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol. J Neurosci (2003) 1.44
Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Curr Biol (2008) 1.44
Inactivation of the lateral but not medial dorsal striatum eliminates the excitatory impact of Pavlovian stimuli on instrumental responding. J Neurosci (2007) 1.44
Amygdala neurons differentially encode motivation and reinforcement. J Neurosci (2007) 1.41
Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma. Proc Natl Acad Sci U S A (2008) 1.41
Excessive alcohol consumption is blocked by glial cell line-derived neurotrophic factor. Alcohol (2009) 1.39
Substantial similarity in amygdala neuronal activity during conditioned appetitive and aversive emotional arousal. Proc Natl Acad Sci U S A (2009) 1.38
Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1. FASEB J (2006) 1.37
Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci (2006) 1.36
Separable roles of the nucleus accumbens core and shell in context- and cue-induced alcohol-seeking. Neuropsychopharmacology (2009) 1.36
GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci U S A (2008) 1.35
Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake. Nat Neurosci (2013) 1.35
Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies. PLoS One (2010) 1.34
Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. J Biol Chem (2003) 1.32
Ethanol seeking triggered by environmental context is attenuated by blocking dopamine D1 receptors in the nucleus accumbens core and shell in rats. Psychopharmacology (Berl) (2009) 1.32
Posterior dorsomedial striatum is critical for both selective instrumental and Pavlovian reward learning. Eur J Neurosci (2010) 1.30
Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse. Nat Neurosci (2013) 1.29
Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration. Mol Cell Biol (2006) 1.27
betagamma Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption. Cell (2002) 1.26
Anxiogenic and aversive effects of corticotropin-releasing factor (CRF) in the bed nucleus of the stria terminalis in the rat: role of CRF receptor subtypes. Psychopharmacology (Berl) (2006) 1.24
Amygdala neural encoding of the absence of reward during extinction. J Neurosci (2010) 1.21
Ethanol-associated cues produce general pavlovian-instrumental transfer. Alcohol Clin Exp Res (2007) 1.20
Spatial and temporal regulation of RACK1 function and N-methyl-D-aspartate receptor activity through WD40 motif-mediated dimerization. J Biol Chem (2004) 1.20
Context-induced relapse of conditioned behavioral responding to ethanol cues in rats. Biol Psychiatry (2008) 1.19
Homer isoforms differentially regulate cocaine-induced neuroplasticity. Neuropsychopharmacology (2006) 1.18
Ethanol alters trafficking and functional N-methyl-D-aspartate receptor NR2 subunit ratio via H-Ras. J Biol Chem (2005) 1.18
Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. J Neurosci (2011) 1.17
PKCbetaII modulates translation independently from mTOR and through RACK1. Biochem J (2008) 1.15
The dopamine D3 receptor is part of a homeostatic pathway regulating ethanol consumption. J Neurosci (2006) 1.15
Altered glutamatergic neurotransmission in the striatum regulates ethanol sensitivity and intake in mice lacking ENT1. Behav Brain Res (2010) 1.15
Escalating ethanol intake is associated with altered corticostriatal BDNF expression. J Neurochem (2009) 1.13
Reinstated ethanol-seeking in rats is modulated by environmental context and requires the nucleus accumbens core. Eur J Neurosci (2008) 1.13
Ethanol operant self-administration in rats is regulated by adenosine A2 receptors. Alcohol Clin Exp Res (2004) 1.13
Safety encoding in the basal amygdala. J Neurosci (2013) 1.13
The nucleus accumbens core and shell are critical for the expression, but not the consolidation, of Pavlovian conditioned approach. Behav Brain Res (2008) 1.12
The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal (2009) 1.12
Extrasynaptic delta-containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake. Proc Natl Acad Sci U S A (2011) 1.12
Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. J Biol Chem (2007) 1.09
Methylphenidate facilitates learning-induced amygdala plasticity. Nat Neurosci (2010) 1.09
Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol. J Neurosci (2009) 1.08
Alcohol seeking in C57BL/6 mice induced by conditioned cues and contexts in the extinction-reinstatement model. Alcohol (2006) 1.07
AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors. Biol Psychiatry (2011) 1.07
Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption. J Neurosci (2005) 1.07
GDNF--a potential target to treat addiction. Pharmacol Ther (2008) 1.07