Published in Nature on November 18, 2004
Developmental plasticity and the origin of species differences. Proc Natl Acad Sci U S A (2005) 3.29
Foot strike patterns and collision forces in habitually barefoot versus shod runners. Nature (2010) 2.94
The childhood obesity epidemic as a result of nongenetic evolution: the maternal resources hypothesis. Mayo Clin Proc (2014) 2.86
Woody cover and hominin environments in the past 6 million years. Nature (2011) 2.66
The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives. J Exp Biol (2011) 2.34
Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell (2013) 2.17
Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans. Proc Natl Acad Sci U S A (2008) 2.15
Gene copy number variation spanning 60 million years of human and primate evolution. Genome Res (2007) 2.02
N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. Mol Cell Biol (2007) 1.87
High-temperature environments of human evolution in East Africa based on bond ordering in paleosol carbonates. Proc Natl Acad Sci U S A (2010) 1.77
Explaining human uniqueness: genome interactions with environment, behaviour and culture. Nat Rev Genet (2008) 1.67
Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. Antioxid Redox Signal (2012) 1.60
Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness. PLoS Biol (2014) 1.56
The foot of Homo floresiensis. Nature (2009) 1.53
The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell (2013) 1.51
Evolution of genetic and genomic features unique to the human lineage. Nat Rev Genet (2012) 1.44
Similarity of polygenic profiles limits the potential for elite human physical performance. J Physiol (2007) 1.33
Genetic architecture of voluntary exercise in an advanced intercross line of mice. Physiol Genomics (2010) 1.30
Leg length, body proportion, and health: a review with a note on beauty. Int J Environ Res Public Health (2010) 1.30
Behavioural defences in animals against pathogens and parasites: parallels with the pillars of medicine in humans. Philos Trans R Soc Lond B Biol Sci (2011) 1.23
Disease prevention--should we target obesity or sedentary lifestyle? Nat Rev Cardiol (2010) 1.22
Heart disease is common in humans and chimpanzees, but is caused by different pathological processes. Evol Appl (2009) 1.22
The up and down bobbing of human walking: a compromise between muscle work and efficiency. J Physiol (2007) 1.22
Development and the evolvability of human limbs. Proc Natl Acad Sci U S A (2010) 1.19
Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs. Physiol Rev (2015) 1.19
Locomotion and posture from the common hominoid ancestor to fully modern hominins, with special reference to the last common panin/hominin ancestor. J Anat (2008) 1.19
Physical activity when young provides lifelong benefits to cortical bone size and strength in men. Proc Natl Acad Sci U S A (2014) 1.18
The jewels of our genome: the search for the genomic changes underlying the evolutionarily unique capacities of the human brain. PLoS Genet (2006) 1.12
Targeted exercises against hip fragility. Osteoporos Int (2008) 1.12
Elastic energy storage in the shoulder and the evolution of high-speed throwing in Homo. Nature (2013) 1.11
Architecture, constraints, and behavior. Proc Natl Acad Sci U S A (2011) 1.07
Evolutionary aspects of human exercise--born to run purposefully. Ageing Res Rev (2012) 1.07
Exercise, energy intake, glucose homeostasis, and the brain. J Neurosci (2014) 1.06
The human foot and heel-sole-toe walking strategy: a mechanism enabling an inverted pendular gait with low isometric muscle force? J R Soc Interface (2012) 1.00
Bone quality: an empty term. PLoS Med (2007) 1.00
Cross-sectional geometry of weight-bearing tibia in female athletes subjected to different exercise loadings. Osteoporos Int (2009) 0.99
Divergent patterns of recent retroviral integrations in the human and chimpanzee genomes: probable transmissions between other primates and chimpanzees. J Virol (2006) 0.97
A synthesis of the theories and concepts of early human evolution. Philos Trans R Soc Lond B Biol Sci (2015) 0.96
The origin of human multi-modal communication. Philos Trans R Soc Lond B Biol Sci (2014) 0.96
Variation in foot strike patterns during running among habitually barefoot populations. PLoS One (2013) 0.96
Running forward: new frontiers in endurance exercise biology. Circulation (2014) 0.94
Impact of meat and Lower Palaeolithic food processing techniques on chewing in humans. Nature (2016) 0.94
Exercise-induced endocannabinoid signaling is modulated by intensity. Eur J Appl Physiol (2012) 0.94
Foot anatomy specialization for postural sensation and control. J Neurophysiol (2011) 0.93
Oldest evidence of tool making hominins in a grassland-dominated ecosystem. PLoS One (2009) 0.92
Electromyography activity across gait and incline: The impact of muscular activity on human morphology. Am J Phys Anthropol (2010) 0.92
Lucy's flat feet: the relationship between the ankle and rearfoot arching in early hominins. PLoS One (2010) 0.91
Arboreality, terrestriality and bipedalism. Philos Trans R Soc Lond B Biol Sci (2010) 0.91
The evolution of the human pelvis: changing adaptations to bipedalism, obstetrics and thermoregulation. Philos Trans R Soc Lond B Biol Sci (2015) 0.91
A relationship between attractiveness and performance in professional cyclists. Biol Lett (2014) 0.90
Genetic determinants of voluntary exercise. Trends Genet (2013) 0.90
Ultramarathon is an outstanding model for the study of adaptive responses to extreme load and stress. BMC Med (2012) 0.89
Physical activity reduces the risk of fragility fracture. PLoS Med (2007) 0.89
Relationship between exercise capacity and brain size in mammals. PLoS One (2011) 0.89
Exercise, APOE genotype, and the evolution of the human lifespan. Trends Neurosci (2014) 0.89
Mechanisms governing the health and performance benefits of exercise. Br J Pharmacol (2013) 0.89
The evolution of the upright posture and gait--a review and a new synthesis. Naturwissenschaften (2010) 0.88
Non-thermal modification of heat-loss responses during exercise in humans. Eur J Appl Physiol (2010) 0.86
The musculoskeletal system of humans is not tuned to maximize the economy of locomotion. Proc Natl Acad Sci U S A (2011) 0.86
Agrarian diet and diseases of affluence--do evolutionary novel dietary lectins cause leptin resistance? BMC Endocr Disord (2005) 0.85
Gracility of the modern Homo sapiens skeleton is the result of decreased biomechanical loading. Proc Natl Acad Sci U S A (2014) 0.85
An experimental investigation of the functional hypothesis and evolutionary advantage of stone-tipped spears. PLoS One (2014) 0.84
Differing evolutionary histories of the ACTN3*R577X polymorphism among the major human geographic groups. PLoS One (2015) 0.84
Impact loading and locomotor-respiratory coordination significantly influence breathing dynamics in running humans. PLoS One (2013) 0.83
Plasticity and modular control of locomotor patterns in neurological disorders with motor deficits. Front Comput Neurosci (2013) 0.83
Linking brains and brawn: exercise and the evolution of human neurobiology. Proc Biol Sci (2013) 0.83
Evolutionary Developmental Biology and Human Language Evolution: Constraints on Adaptation. Evol Biol (2012) 0.82
Why control activity? Evolutionary selection pressures affecting the development of physical activity genetic and biological regulation. Biomed Res Int (2013) 0.82
Effects of Physical (In)activity on Platelet Function. Biomed Res Int (2015) 0.82
Cardiac output and performance during a marathon race in middle-aged recreational runners. ScientificWorldJournal (2012) 0.82
Motivational and evolutionary aspects of a physical exercise training program: a longitudinal study. Front Psychol (2015) 0.82
A genetic basis of variation in eccrine sweat gland and hair follicle density. Proc Natl Acad Sci U S A (2015) 0.82
Body composition in Pan paniscus compared with Homo sapiens has implications for changes during human evolution. Proc Natl Acad Sci U S A (2015) 0.81
Cellular mechanisms of skin repair in humans and other mammals. J Cell Commun Signal (2016) 0.81
Superior pattern processing is the essence of the evolved human brain. Front Neurosci (2014) 0.81
Trunk orientation, stability, and quadrupedalism. Front Neurol (2013) 0.80
Challenging oneself intermittently to improve health. Dose Response (2014) 0.80
Human evolution: Those feet in ancient times. Nature (2012) 0.80
Biomechanical overload syndrome: defining a new diagnosis. Br J Sports Med (2012) 0.80
Recent origin of low trabecular bone density in modern humans. Proc Natl Acad Sci U S A (2014) 0.80
Exercise mitigates the stunting effect of cold temperature on limb elongation in mice by increasing solute delivery to the growth plate. J Appl Physiol (1985) (2010) 0.80
Human risk of diseases associated with red meat intake: Analysis of current theories and proposed role for metabolic incorporation of a non-human sialic acid. Mol Aspects Med (2016) 0.79
Social Bonds and Exercise: Evidence for a Reciprocal Relationship. PLoS One (2015) 0.79
The colours of humanity: the evolution of pigmentation in the human lineage. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection. Genome Res (2016) 0.79
Temporal labyrinths of eastern Eurasian Pleistocene humans. Proc Natl Acad Sci U S A (2014) 0.79
Shoes alter the spring-like function of the human foot during running. J R Soc Interface (2016) 0.78
Six Weeks Habituation of Simulated Barefoot Running Induces Neuromuscular Adaptations and Changes in Foot Strike Patterns in Female Runners. Med Sci Monit (2015) 0.78
Running from Paris to Beijing: biomechanical and physiological consequences. Eur J Appl Physiol (2009) 0.78
Evolution of the human hip. Part 1: the osseous framework. J Hip Preserv Surg (2014) 0.78
Exercise and cognitive function: a hypothesis for the association of type II diabetes mellitus and Alzheimer's disease from an evolutionary perspective. Diabetol Metab Syndr (2009) 0.78
Physical activity completed when young has residual bone benefits at 94 years of age: a within-subject controlled case study. J Musculoskelet Neuronal Interact (2014) 0.78
Confrontational scavenging as a possible source for language and cooperation. BMC Evol Biol (2011) 0.78
Olympics: Run for your life. Nature (2012) 0.78
The Foot's Arch and the Energetics of Human Locomotion. Sci Rep (2016) 0.78
Involvement of the TRPV1 channel in the modulation of spontaneous locomotor activity, physical performance and physical exercise-induced physiological responses. Braz J Med Biol Res (2016) 0.77
Muscle activation during maximal effort tasks: evidence of the selective forces that shaped the musculoskeletal system of humans. Biol Open (2015) 0.77
Robust efficiency and actuator saturation explain healthy heart rate control and variability. Proc Natl Acad Sci U S A (2014) 0.77
Palaeoanthropology: Homo floresiensis from head to toe. Nature (2009) 0.77
Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell (2013) 2.17
Virtual cranial reconstruction of Sahelanthropus tchadensis. Nature (2005) 1.72
The aging of Wolff's "law": ontogeny and responses to mechanical loading in cortical bone. Am J Phys Anthropol (2004) 1.71
New material of the earliest hominid from the Upper Miocene of Chad. Nature (2005) 1.66
Fetal load and the evolution of lumbar lordosis in bipedal hominins. Nature (2007) 1.52
The development of sex differences in digital formula from infancy in the Fels Longitudinal Study. Proc Biol Sci (2005) 1.45
Effects of footwear and strike type on running economy. Med Sci Sports Exerc (2012) 1.34
Foot strike and injury rates in endurance runners: a retrospective study. Med Sci Sports Exerc (2012) 1.34
A Wolff in sheep's clothing: trabecular bone adaptation in response to changes in joint loading orientation. Bone (2011) 1.26
Control and function of arm swing in human walking and running. J Exp Biol (2009) 1.19
Walking, running and the evolution of short toes in humans. J Exp Biol (2009) 1.15
Hyoid and tongue surface movements in speaking and eating. Arch Oral Biol (2002) 1.14
Elastic energy storage in the shoulder and the evolution of high-speed throwing in Homo. Nature (2013) 1.11
Seasonal fluctuations in birth weight and neonatal limb length; does prenatal vitamin D influence neonatal size and shape? Early Hum Dev (2005) 1.09
Mouse models and the evolutionary developmental biology of the skull. Integr Comp Biol (2008) 1.07
Middle cranial fossa anatomy and the origin of modern humans. Anat Rec (Hoboken) (2008) 0.98
Hand biomechanics during simulated stone tool use. J Hum Evol (2011) 0.95
Evolution of covariance in the mammalian skull. Novartis Found Symp (2007) 0.94
The effect of humeral torsion on rotational range of motion in the shoulder and throwing performance. J Anat (2012) 0.94
Season of birth is associated with anthropometric and neurocognitive outcomes during infancy and childhood in a general population birth cohort. Schizophr Res (2005) 0.93
Morphological affinities of the Sahelanthropus tchadensis (Late Miocene hominid from Chad) cranium. Proc Natl Acad Sci U S A (2005) 0.88
The coevolution of human hands and feet. Evolution (2010) 0.88
Calcaneus length determines running economy: implications for endurance running performance in modern humans and Neandertals. J Hum Evol (2011) 0.87
Bite force and occlusal stress production in hominin evolution. Am J Phys Anthropol (2013) 0.86
The influence of masticatory loading on craniofacial morphology: A test case across technological transitions in the Ohio valley. Am J Phys Anthropol (2010) 0.86
Free-living physical activity and energy expenditure of rural children and adolescents in the Nandi region of Kenya. Ann Hum Biol (2013) 0.84
Aerobic Capacity, Activity Levels and Daily Energy Expenditure in Male and Female Adolescents of the Kenyan Nandi Sub-Group. PLoS One (2013) 0.83
Of mice, rats and men: trabecular bone architecture in mammals scales to body mass with negative allometry. J Struct Biol (2013) 0.82
The evolution of endurance running and the tyranny of ethnography: a reply to Pickering and Bunn (2007). J Hum Evol (2007) 0.82
The Story of the Human Body: Evolution, Health and Disease. Fam Med (2016) 0.81
Human evolution: Those feet in ancient times. Nature (2012) 0.80
Palaeoanthropology: homing in on early Homo. Nature (2007) 0.77
Variation in estradiol level affects cortical bone growth in response to mechanical loading in sheep. J Exp Biol (2007) 0.77
Trabecular evidence for a human-like gait in Australopithecus africanus. PLoS One (2013) 0.77
Palaeoanthropology: Homo floresiensis from head to toe. Nature (2009) 0.77
Directional differences in the biaxial material properties of fascia lata and the implications for fascia function. Ann Biomed Eng (2014) 0.76
Cranial base flexion and H. erectus skulls. Science (2003) 0.75
Palaeoanthropology: further fossil finds from Flores. Nature (2005) 0.75
Extreme Endurance Exercise and Progressive Coronary Artery Disease. J Am Coll Cardiol (2017) 0.75