Published in Hepatology on December 01, 2004
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev (2005) 2.02
Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. Genome Res (2010) 1.67
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways. Elife (2014) 1.01
Loss of HNF6 expression correlates with human pancreatic cancer progression. Lab Invest (2014) 0.95
Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol (2006) 0.94
Transcriptional activation by growth hormone of HNF-6-regulated hepatic genes, a potential mechanism for improved liver repair during biliary injury in mice. Am J Physiol Gastrointest Liver Physiol (2008) 0.93
Molecular mechanisms of bile duct development. Int J Biochem Cell Biol (2010) 0.92
Effects of contraction and insulin on protein synthesis, AMP-activated protein kinase and phosphorylation state of translation factors in rat skeletal muscle. Pflugers Arch (2007) 0.89
Differential transcriptional characteristics of small and large biliary epithelial cells derived from small and large bile ducts. Am J Physiol Gastrointest Liver Physiol (2010) 0.86
The Onecut transcription factor HNF-6 regulates in motor neurons the formation of the neuromuscular junctions. PLoS One (2012) 0.80
Cross Talk Between GH-Regulated Transcription Factors HNF6 and CUX2 in Adult Mouse Liver. Mol Endocrinol (2015) 0.77
Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice. BMC Genomics (2016) 0.77
Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas. Semin Cell Dev Biol (2016) 0.76
HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms. Genes Dev (2016) 0.75
Onecut transcription factors in development and disease. Trends Dev Biol (2016) 0.75
New Tools for Molecular Therapy of Hepatocellular Carcinoma. Diseases (2015) 0.75
Organogenesis and development of the liver. Dev Cell (2010) 3.71
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology (2011) 3.19
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology (2010) 3.16
The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development (2002) 2.89
Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host Microbe (2009) 2.58
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology (2006) 2.10
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev (2005) 2.02
The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade. Dev Biol (2003) 1.94
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis. Hepatology (2011) 1.84
Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell (2008) 1.70
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol (2009) 1.52
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas. Hum Mol Genet (2003) 1.50
Biliary differentiation and bile duct morphogenesis in development and disease. Int J Biochem Cell Biol (2009) 1.47
Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos. Hepatology (2002) 1.45
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. Biochem J (2004) 1.45
A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation. Gastroenterology (2011) 1.44
An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev Biol (2006) 1.39
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo. Proc Natl Acad Sci U S A (2011) 1.35
Plasticity of a transcriptional regulation network among alpha-proteobacteria is supported by the identification of CtrA targets in Brucella abortus. Mol Microbiol (2002) 1.21
The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration. Dev Biol (2007) 1.20
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol (2010) 1.20
Shh-dependent differentiation of intestinal tissue from embryonic pancreas by activin A. J Cell Sci (2004) 1.19
Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver. J Biol Chem (2004) 1.14
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut (2012) 1.14
A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells. Diabetes (2006) 1.13
Plasticity of hepatic cell differentiation: bipotential adult mouse liver clonal cell lines competent to differentiate in vitro and in vivo. Stem Cells (2006) 1.11
Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers. Stem Cells (2007) 1.09
Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol (2009) 1.09
Control of hepatic differentiation by activin/TGFbeta signaling. Cell Cycle (2006) 1.05
Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes. Proc Natl Acad Sci U S A (2004) 1.04
Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas. Dev Biol (2010) 1.04
Lymphocytes support oval cell-dependent liver regeneration. J Immunol (2008) 0.98
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest (2015) 0.95
Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol (2006) 0.94
Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2. Gene Expr Patterns (2003) 0.94
Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression. BMC Mol Biol (2014) 0.93
Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Development (2012) 0.93
Developmentally regulated N-terminal variants of the nuclear receptor hepatocyte nuclear factor 4alpha mediate multiple interactions through coactivator and corepressor-histone deacetylase complexes. J Biol Chem (2002) 0.93
MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun (2009) 0.93
Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6. Gastroenterology (2013) 0.92
Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns (2006) 0.92
The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm. J Biol Chem (2004) 0.92
In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J (2006) 0.92
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. J Cell Biol (2014) 0.91
Increased protein glycation in fructosamine 3-kinase-deficient mice. Biochem J (2006) 0.91
IFN-ε is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines. PLoS One (2013) 0.91
Interaction between Hhex and SOX13 modulates Wnt/TCF activity. J Biol Chem (2009) 0.90
Lack of cilia and differentiation defects in the liver of human foetuses with the Meckel syndrome. Liver Int (2007) 0.90
Gene transfer into mouse prepancreatic endoderm by whole embryo electroporation. JOP (2005) 0.90
Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol (2007) 0.90
Class III phosphoinositide 3-kinase/VPS34 and dynamin are critical for apical endocytic recycling. Traffic (2013) 0.88
Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. J Comp Neurol (2012) 0.88
Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol (2013) 0.87
Hepatic artery malformations associated with a primary defect in intrahepatic bile duct development. J Hepatol (2003) 0.87
Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cord. PLoS One (2013) 0.87
Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development. Biol Open (2012) 0.86
Embryonic liver cells and permanent lines as models for hepatocyte and bile duct cell differentiation. Mech Dev (2003) 0.85
Gamma c cytokines condition the progressive differentiation of CD4+ T cells. Proc Natl Acad Sci U S A (2007) 0.84
Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells. J Hepatol (2008) 0.83
Cell therapy for the diseased liver: from stem cell biology to novel models for hepatotropic human pathogens. Dis Model Mech (2008) 0.83
OC-3, a novel mammalian member of the ONECUT class of transcription factors. Biochem Biophys Res Commun (2002) 0.83
Intracellular targeting of the type-I alpha regulatory subunit of cAMP-dependent protein kinase. Trends Cardiovasc Med (2002) 0.82
Hepatocyte nuclear factor-6 stimulates transcription of the alpha-fetoprotein gene and synergizes with the retinoic-acid-receptor-related orphan receptor alpha-4. Biochem J (2003) 0.82