Published in Biochem J on October 15, 2006
L-2-hydroxyglutaric aciduria, a defect of metabolite repair. J Inherit Metab Dis (2007) 2.02
L: -2-Hydroxyglutaric aciduria, a disorder of metabolite repair. J Inherit Metab Dis (2008) 1.40
Role of advanced glycation end products in cellular signaling. Redox Biol (2014) 1.36
Expression of biomass-degrading enzymes is a major event during conidium development in Trichoderma reesei. Eukaryot Cell (2011) 1.10
Advanced glycation end products, diabetes and ageing. Z Gerontol Geriatr (2007) 0.97
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues. Biochemistry (2011) 0.91
Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cell Mol Life Sci (2010) 0.89
Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles. J Lipid Res (2014) 0.89
Homocysteine methyltransferases Mht1 and Sam4 prevent the accumulation of age-damaged (R,S)-AdoMet in the yeast Saccharomyces cerevisiae. J Biol Chem (2010) 0.84
The fructosamine 3-kinase knockout mouse: a tool for testing the glycation hypothesis of intracellular protein damage in diabetes and aging. Biochem J (2006) 0.82
Medical bioremediation of age-related diseases. Microb Cell Fact (2009) 0.76
Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells. PLoS One (2014) 0.76
Identification of protein-ribulosamine-5-phosphatase as human low-molecular-mass protein tyrosine phosphatase-A. Biochem J (2007) 0.75
Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases. Histochem Cell Biol (2016) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell (1991) 14.23
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals. Proc Natl Acad Sci U S A (2001) 3.62
Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med (1984) 3.14
The glucose transporter family: structure, function and tissue-specific expression. Biochem J (1993) 3.00
Repair of oxidized proteins. Identification of a new methionine sulfoxide reductase. J Biol Chem (2001) 2.40
Lilly Lecture 1993. Glycation and diabetic complications. Diabetes (1994) 1.92
Aging as war between chemical and biochemical processes: protein methylation and the recognition of age-damaged proteins for repair. Ageing Res Rev (2003) 1.90
Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice. Proc Natl Acad Sci U S A (1997) 1.75
Fructosamine 3-kinase is involved in an intracellular deglycation pathway in human erythrocytes. Biochem J (2002) 1.70
The Amadori product on protein: structure and reactions. Prog Clin Biol Res (1989) 1.61
The Amadori rearrangement. Adv Carbohydr Chem (1955) 1.60
Enzymes that catalyse the restructuring of proteins. Curr Opin Struct Biol (2000) 1.58
Sites of nonenzymatic glycosylation of human hemoglobin A. J Biol Chem (1980) 1.56
Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase. Biochemistry (1999) 1.38
Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase. Diabetes (2000) 1.34
Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo. Diabetes (2001) 1.25
Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli. J Biol Chem (2002) 1.20
Metabolic transit of early and advanced Maillard products. Prog Food Nutr Sci (1981) 1.10
Use of protein-based standards in automated colorimetric determinations of fructosamine in serum. Clin Chem (1985) 1.08
Phenotypic analysis of seizure-prone mice lacking L-isoaspartate (D-aspartate) O-methyltransferase. J Biol Chem (1999) 1.04
Identification of fructosamine residues deglycated by fructosamine-3-kinase in human hemoglobin. J Biol Chem (2004) 1.01
A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines. Diabetes (2003) 0.94
Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein. J Biol Chem (2004) 0.93
Some clues as to the regulation, expression, function, and distribution of fructosamine-3-kinase and fructosamine-3-kinase-related protein. Ann N Y Acad Sci (2005) 0.91
Transport and metabolism studies with fructose amino acids. Prog Food Nutr Sci (1981) 0.87
Variability in erythrocyte fructosamine 3-kinase activity in humans correlates with polymorphisms in the FN3K gene and impacts on haemoglobin glycation at specific sites. Diabetes Metab (2006) 0.86
Application of affinity chromatography for separation and quantitation of glycosylated hemoglobins. J Lab Clin Med (1983) 0.83
Nutritional and metabolic consequences of the early Maillard reaction of heat treated milk in the pig. Significance for man. Eur J Nutr (2002) 0.78
Tolvaptan in patients with autosomal dominant polycystic kidney disease. N Engl J Med (2012) 9.88
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med (2003) 7.86
Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria. Am J Hum Genet (2004) 4.08
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Gastroenterology (2012) 3.34
Evolving importance of kidney disease: from subspecialty to global health burden. Lancet (2013) 3.30
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology (2011) 3.19
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development (2002) 2.89
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat Genet (2011) 2.74
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Curr Biol (2002) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Vitamin C. Biosynthesis, recycling and degradation in mammals. FEBS J (2007) 2.55
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis. J Biol Chem (2003) 2.45
Cubilin is essential for albumin reabsorption in the renal proximal tubule. J Am Soc Nephrol (2010) 2.42
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. J Biol Chem (2006) 2.29
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491. J Biol Chem (2005) 2.24
A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria. Proc Natl Acad Sci U S A (2004) 2.19
The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology (2006) 2.10
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev (2005) 2.02
High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease. Kidney Int (2005) 2.02
Mutations in SEC63 cause autosomal dominant polycystic liver disease. Nat Genet (2004) 1.96
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proc Natl Acad Sci U S A (2003) 1.87
Transcriptional and functional analyses of SLC12A3 mutations: new clues for the pathogenesis of Gitelman syndrome. J Am Soc Nephrol (2007) 1.84
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis. Hepatology (2011) 1.84
A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin. J Am Soc Nephrol (2003) 1.77
Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen. J Exp Med (2005) 1.75
Progression of coronary artery calcification and thoracic aorta calcification in kidney transplant recipients. Am J Kidney Dis (2011) 1.74
Identification of a dehydrogenase acting on D-2-hydroxyglutarate. Biochem J (2004) 1.72
Fructosamine 3-kinase is involved in an intracellular deglycation pathway in human erythrocytes. Biochem J (2002) 1.70
Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules. Proc Natl Acad Sci U S A (2010) 1.70
Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. Genome Res (2010) 1.67
A role for Rhesus factor Rhcg in renal ammonium excretion and male fertility. Nature (2008) 1.61
Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria. Mol Microbiol (2012) 1.61
PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli. Biochem J (2013) 1.60
Autosomal dominant polycystic kidney disease is associated with central and nephrogenic defects in osmoregulation. Kidney Int (2012) 1.58
Spectrum of mutations in Gitelman syndrome. J Am Soc Nephrol (2011) 1.57
The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease. Kidney Int (2011) 1.56
Metabolite damage and its repair or pre-emption. Nat Chem Biol (2013) 1.50
Coronary artery calcification: a strong predictor of cardiovascular events in renal transplant recipients. Nephrol Dial Transplant (2010) 1.50
Influence of the endothelial nitric oxide synthase gene on conventional and ambulatory blood pressure: sib-pair analysis and haplotype study. J Hypertens (2005) 1.48
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. Biochem J (2004) 1.45
L-carnitine is an osmotic agent suitable for peritoneal dialysis. Kidney Int (2011) 1.45
A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation. Gastroenterology (2011) 1.44
An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells. Eur J Pharm Sci (2007) 1.43
A periplasmic reducing system protects single cysteine residues from oxidation. Science (2009) 1.42
Regulated acid-base transport in the collecting duct. Pflugers Arch (2009) 1.42
Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases. Cancer Res (2012) 1.41
Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 Study. Am J Kidney Dis (2011) 1.39
Tamm-Horsfall protein or uromodulin: new ideas about an old molecule. Nephrol Dial Transplant (2005) 1.25
Gitelman's syndrome: towards genotype-phenotype correlations? Pediatr Nephrol (2006) 1.24
A primary culture of mouse proximal tubular cells, established on collagen-coated membranes. Am J Physiol Renal Physiol (2007) 1.22
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells. Proc Natl Acad Sci U S A (2007) 1.21
The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration. Dev Biol (2007) 1.20
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol (2010) 1.20
TMEM165 deficiency causes a congenital disorder of glycosylation. Am J Hum Genet (2012) 1.20
CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia. Am J Hum Genet (2011) 1.20
Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli. J Biol Chem (2002) 1.20
AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase. J Biol Chem (2008) 1.19
Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis. Proc Natl Acad Sci U S A (2008) 1.18
Renal phenotype of the cystinosis mouse model is dependent upon genetic background. Nephrol Dial Transplant (2009) 1.18
Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase. J Biol Chem (2001) 1.16
Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. Retrovirology (2012) 1.16
Aortic stiffness and central wave reflections predict outcome in renal transplant recipients. Hypertension (2011) 1.15
MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. PLoS One (2011) 1.15
Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver. J Biol Chem (2004) 1.14
Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1). J Biol Chem (2010) 1.14
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut (2012) 1.14
A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells. Diabetes (2006) 1.13
A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure. Hum Mol Genet (2010) 1.13
Pituitary stalk hemangioblastoma: the fourth case report and review of the literature. Clin Neurol Neurosurg (2006) 1.12
New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases. Mol Cell Biol (2006) 1.11
Anti-IL-17A autovaccination prevents clinical and histological manifestations of experimental autoimmune encephalomyelitis. Ann N Y Acad Sci (2007) 1.11
Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair. J Biol Chem (2011) 1.10
Molecular Physiology of Water Balance. N Engl J Med (2015) 1.10
Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2. J Biol Chem (2003) 1.10
Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma. Mol Cancer (2007) 1.09
Phenotype and outcome in hereditary tubulointerstitial nephritis secondary to UMOD mutations. Clin J Am Soc Nephrol (2011) 1.09
Expression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney development. Am J Pathol (2002) 1.08
The effect of common uromodulin variants on urinary protein level and gene transcription. Kidney Int (2013) 1.08
Diagnosis, management, and prognosis of HNF1B nephropathy in adulthood. Kidney Int (2011) 1.07
CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease. Am J Physiol Renal Physiol (2009) 1.06
Renal cyst infection in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant (2007) 1.05
Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver. Hepatology (2004) 1.05
Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease. Biochim Biophys Acta (2011) 1.05
The protein-disulfide isomerase DsbC cooperates with SurA and DsbA in the assembly of the essential β-barrel protein LptD. J Biol Chem (2010) 1.03
Renal expression of parvalbumin is critical for NaCl handling and response to diuretics. Proc Natl Acad Sci U S A (2007) 1.03
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase. Biochem J (2012) 1.03
Identification of in vivo phosphorylation sites on human deoxycytidine kinase. Role of Ser-74 in the control of enzyme activity. J Biol Chem (2005) 1.03