Published in Biomaterials on May 01, 2005
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules (2011) 2.24
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J Control Release (2008) 1.72
Three-dimensional scaffolds for tissue engineering applications: role of porosity and pore size. Tissue Eng Part B Rev (2013) 1.60
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Biodegradation of silk biomaterials. Int J Mol Sci (2009) 1.55
In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. Biomaterials (2008) 1.51
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix. Tissue Eng Part A (2009) 1.44
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Rheological properties of peptide-based hydrogels for biomedical and other applications. Chem Soc Rev (2010) 1.37
Silk-based delivery systems of bioactive molecules. Adv Drug Deliv Rev (2010) 1.37
Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A (2006) 1.34
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Comparative chondrogenesis of human cell sources in 3D scaffolds. J Tissue Eng Regen Med (2009) 1.31
In vitro 3D model for human vascularized adipose tissue. Tissue Eng Part A (2009) 1.29
Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials (2009) 1.29
Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev (2010) 1.25
Gel spinning of silk tubes for tissue engineering. Biomaterials (2008) 1.24
Collagen scaffolds populated with human marrow stromal cells reduce lesion volume and improve functional outcome after traumatic brain injury. Neurosurgery (2007) 1.24
Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine. Semin Cell Dev Biol (2009) 1.21
Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells. Acta Biomater (2012) 1.18
Evaluation of gel spun silk-based biomaterials in a murine model of bladder augmentation. Biomaterials (2010) 1.18
Antiepileptic effects of silk-polymer based adenosine release in kindled rats. Exp Neurol (2009) 1.18
Multilayered silk scaffolds for meniscus tissue engineering. Biomaterials (2010) 1.18
Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses. Biomaterials (2007) 1.17
Biomedical applications of chemically-modified silk fibroin. J Mater Chem (2009) 1.17
Response of human corneal fibroblasts on silk film surface patterns. Macromol Biosci (2010) 1.14
Nanofibrous architecture of silk fibroin scaffolds prepared with a mild self-assembly process. Biomaterials (2010) 1.14
Helicoidal multi-lamellar features of RGD-functionalized silk biomaterials for corneal tissue engineering. Biomaterials (2010) 1.12
Relationships between degradability of silk scaffolds and osteogenesis. Biomaterials (2010) 1.11
The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials (2011) 1.11
Effect of hydration on silk film material properties. Macromol Biosci (2010) 1.09
Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty. Biomaterials (2013) 1.08
Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts. Biomaterials (2009) 1.06
Degradation mechanism and control of silk fibroin. Biomacromolecules (2011) 1.06
Silk fibroin electrogelation mechanisms. Acta Biomater (2011) 1.04
The use of bi-layer silk fibroin scaffolds and small intestinal submucosa matrices to support bladder tissue regeneration in a rat model of spinal cord injury. Biomaterials (2014) 1.04
Silkworm and spider silk scaffolds for chondrocyte support. J Mater Sci Mater Med (2008) 1.02
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs. Chem Rev (2016) 1.02
Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors. J R Soc Interface (2008) 1.01
Genipin-crosslinked cartilage-derived matrix as a scaffold for human adipose-derived stem cell chondrogenesis. Tissue Eng Part A (2012) 1.01
Antibiotic-Releasing Silk Biomaterials for Infection Prevention and Treatment. Adv Funct Mater (2012) 0.99
A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis. Biomaterials (2011) 0.99
A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs. Biomaterials (2012) 0.99
Reinforcing silk scaffolds with silk particles. Macromol Biosci (2010) 0.98
The effect of manipulation of silk scaffold fabrication parameters on matrix performance in a murine model of bladder augmentation. Biomaterials (2011) 0.97
Mechanical improvements to reinforced porous silk scaffolds. J Biomed Mater Res A (2011) 0.97
The performance of silk scaffolds in a rat model of augmentation cystoplasty. Biomaterials (2013) 0.96
Charge-Tunable Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Adv Funct Mater (2013) 0.95
Interactions between spider silk and cells--NIH/3T3 fibroblasts seeded on miniature weaving frames. PLoS One (2010) 0.94
Silk hydrogel for cartilage tissue engineering. J Biomed Mater Res B Appl Biomater (2010) 0.94
Non-invasive characterization of structure and morphology of silk fibroin biomaterials using non-linear microscopy. Biomaterials (2008) 0.93
Adipogenic differentiation of human adipose-derived stem cells on 3D silk scaffolds. Methods Mol Biol (2011) 0.92
Mechanisms of controlled release from silk fibroin films. Biomacromolecules (2011) 0.91
Cervical tissue engineering using silk scaffolds and human cervical cells. Tissue Eng Part A (2010) 0.91
Sustained volume retention in vivo with adipocyte and lipoaspirate seeded silk scaffolds. Biomaterials (2013) 0.91
Sustainable three-dimensional tissue model of human adipose tissue. Tissue Eng Part C Methods (2013) 0.90
Engineering cartilage and bone using human mesenchymal stem cells. J Orthop Sci (2007) 0.89
Tissue engineering a surrogate niche for metastatic cancer cells. Biomaterials (2015) 0.88
Human adipose-derived cells can serve as a single-cell source for the in vitro cultivation of vascularized bone grafts. J Tissue Eng Regen Med (2012) 0.88
Salt-leached silk scaffolds with tunable mechanical properties. Biomacromolecules (2012) 0.88
Hypoxia and amino acid supplementation synergistically promote the osteogenesis of human mesenchymal stem cells on silk protein scaffolds. Tissue Eng Part A (2010) 0.87
Impact of processing parameters on the haemocompatibility of Bombyx mori silk films. Biomaterials (2011) 0.86
Impact of silk biomaterial structure on proteolysis. Acta Biomater (2014) 0.86
Stem cell-based meniscus tissue engineering. Tissue Eng Part A (2011) 0.86
Reversible hydrogel-solution system of silk with high beta-sheet content. Biomacromolecules (2014) 0.86
Effects of hyperinsulinemia on lipolytic function of three-dimensional adipocyte/endothelial co-cultures. Tissue Eng Part C Methods (2010) 0.86
Evaluation of silk biomaterials in combination with extracellular matrix coatings for bladder tissue engineering with primary and pluripotent cells. PLoS One (2013) 0.85
Chip-based comparison of the osteogenesis of human bone marrow- and adipose tissue-derived mesenchymal stem cells under mechanical stimulation. PLoS One (2012) 0.85
Lipolytic function of adipocyte/endothelial cocultures. Tissue Eng Part A (2011) 0.85
Human stem cell neuronal differentiation on silk-carbon nanotube composite. Nanoscale Res Lett (2012) 0.85
Neural responses to electrical stimulation on patterned silk films. J Biomed Mater Res A (2013) 0.84
Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering. ACS Biomater Sci Eng (2015) 0.83
A mild process to design silk scaffolds with reduced β-sheet structure and various topographies at the nanometer scale. Acta Biomater (2014) 0.83
Human dental pulp progenitor cell behavior on aqueous and hexafluoroisopropanol based silk scaffolds. J Biomed Mater Res A (2011) 0.83
Silk-fibrin/hyaluronic acid composite gels for nucleus pulposus tissue regeneration. Tissue Eng Part A (2011) 0.83
The influence of scaffold material on chondrocytes under inflammatory conditions. Acta Biomater (2013) 0.83
Treatment of traumatic brain injury in mice with bone marrow stromal cell-impregnated collagen scaffolds. J Neurosurg (2009) 0.83
Fabrication and characteristics of chitosan sponge as a tissue engineering scaffold. Biomed Res Int (2014) 0.82
Development of a new carbon nanotube-alginate-hydroxyapatite tricomponent composite scaffold for application in bone tissue engineering. Int J Nanomedicine (2015) 0.82
Characterization of dielectrophoresis-aligned nanofibrous silk fibroin-chitosan scaffold and its interactions with endothelial cells for tissue engineering applications. Acta Biomater (2014) 0.82
Silk as a biocohesive sacrificial binder in the fabrication of hydroxyapatite load bearing scaffolds. Biomaterials (2014) 0.82
Silk Biomaterials with Vascularization Capacity. Adv Funct Mater (2015) 0.81
Acellular bi-layer silk fibroin scaffolds support tissue regeneration in a rabbit model of onlay urethroplasty. PLoS One (2014) 0.81
Silk-based injectable biomaterial as an alternative to cervical cerclage: an in vitro study. Reprod Sci (2012) 0.81
Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols. Bonekey Rep (2016) 0.81
Osteoinductive recombinant silk fusion proteins for bone regeneration. Acta Biomater (2016) 0.80
Acellular bi-layer silk fibroin scaffolds support functional tissue regeneration in a rat model of onlay esophagoplasty. Biomaterials (2015) 0.80
Multiple silk coatings on biphasic calcium phosphate scaffolds: effect on physical and mechanical properties and in vitro osteogenic response of human mesenchymal stem cells. Biomacromolecules (2013) 0.80
Annulus fibrosus tissue engineering using lamellar silk scaffolds. J Tissue Eng Regen Med (2012) 0.80
Biomimetic design and fabrication of porous chitosan–gelatin liver scaffolds with hierarchical channel network. J Mater Sci Mater Med (2014) 0.79
In vitro chondrogenic differentiation of human adipose-derived stem cells with silk scaffolds. J Tissue Eng (2012) 0.79
Evaluation of alginate-chitosan semi IPNs as cartilage scaffolds. J Mater Sci Mater Med (2008) 0.79
Silk-based biomaterials. Biomaterials (2003) 7.72
Mechanism of silk processing in insects and spiders. Nature (2003) 4.85
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. Nat Mater (2010) 4.62
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
New opportunities for an ancient material. Science (2010) 3.95
In vitro degradation of silk fibroin. Biomaterials (2005) 3.56
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials (2006) 3.27
Villification: how the gut gets its villi. Science (2013) 2.94
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules (2004) 2.77
Cell differentiation by mechanical stress. FASEB J (2001) 2.56
Structure and properties of silk hydrogels. Biomacromolecules (2004) 2.50
A physically transient form of silicon electronics. Science (2012) 2.47
Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol (2013) 2.32
Vascularization strategies for tissue engineering. Tissue Eng Part B Rev (2009) 2.31
Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules (2011) 2.24
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater (2010) 2.20
Electrospinning Bombyx mori silk with poly(ethylene oxide). Biomacromolecules (2002) 2.20
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Traffic jams reduce hydrolytic efficiency of cellulase on cellulose surface. Science (2011) 2.09
Macrophage responses to silk. Biomaterials (2003) 2.04
In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials (2005) 2.02
Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials (2005) 1.94
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A (2004) 1.94
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Silk microspheres for encapsulation and controlled release. J Control Release (2006) 1.81
Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules (2008) 1.79
High speed atomic force microscopy visualizes processive movement of Trichoderma reesei cellobiohydrolase I on crystalline cellulose. J Biol Chem (2009) 1.75
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J Control Release (2008) 1.72
Biomaterial films of Bombyx mori silk fibroin with poly(ethylene oxide). Biomacromolecules (2004) 1.70
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays. Proc Natl Acad Sci U S A (2009) 1.69
Twenty-one millisecond pulsars in Terzan 5 using the Green Bank Telescope. Science (2005) 1.68
Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J Biomed Mater Res A (2006) 1.68
Human bone marrow stromal cell responses on electrospun silk fibroin mats. Biomaterials (2004) 1.67
Cartilage tissue engineering with silk scaffolds and human articular chondrocytes. Biomaterials (2006) 1.67
Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Rev (2009) 1.66
Silk fibroin microtubes for blood vessel engineering. Biomaterials (2007) 1.61
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res (2010) 1.61
Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med (2010) 1.60
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Modification of silk fibroin using diazonium coupling chemistry and the effects on hMSC proliferation and differentiation. Biomaterials (2008) 1.59
Silk film biomaterials for cornea tissue engineering. Biomaterials (2008) 1.58
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials (2006) 1.56
Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed (2008) 1.55
Mapping domain structures in silks from insects and spiders related to protein assembly. J Mol Biol (2004) 1.53
Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation. PLoS One (2010) 1.52
Electrospun silk biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev (2009) 1.52
In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. Biomaterials (2008) 1.51
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci U S A (2010) 1.51
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Role of adult mesenchymal stem cells in bone tissue engineering applications: current status and future prospects. Tissue Eng (2005) 1.50
Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res (2007) 1.46
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells. Tissue Eng (2006) 1.45
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Relationships between mechanical properties and extracellular matrix constituents of the cervical stroma during pregnancy. Semin Perinatol (2009) 1.42
Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules (2009) 1.42
Mechanisms of silk fibroin sol-gel transitions. J Phys Chem B (2006) 1.41
Human bone marrow stromal cell and ligament fibroblast responses on RGD-modified silk fibers. J Biomed Mater Res A (2003) 1.40
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Retracted Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. Proc Natl Acad Sci U S A (2012) 1.39
Silk materials--a road to sustainable high technology. Adv Mater (2012) 1.38
Silicon electronics on silk as a path to bioresorbable, implantable devices. Appl Phys Lett (2009) 1.38
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Spider silks and their applications. Trends Biotechnol (2008) 1.37
Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One (2008) 1.37
Silk-based delivery systems of bioactive molecules. Adv Drug Deliv Rev (2010) 1.37
Biomaterials derived from silk-tropoelastin protein systems. Biomaterials (2010) 1.36
Biomaterials for the development of peripheral nerve guidance conduits. Tissue Eng Part B Rev (2011) 1.35
Electrogelation for protein adhesives. Adv Mater (2010) 1.34
Nanoporous cellulose as metal nanoparticles support. Biomacromolecules (2009) 1.34
Silk fibroin biomaterials for controlled release drug delivery. Expert Opin Drug Deliv (2011) 1.34
Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A (2006) 1.34
Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir (2005) 1.34
Genetic engineering of fibrous proteins: spider dragline silk and collagen. Adv Drug Deliv Rev (2002) 1.33
Matrix metalloproteinases and their clinical applications in orthopaedics. Clin Orthop Relat Res (2004) 1.32
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Can tissue engineering concepts advance tumor biology research? Trends Biotechnol (2010) 1.32
Comparative chondrogenesis of human cell sources in 3D scaffolds. J Tissue Eng Regen Med (2009) 1.31
Mechanism of enzymatic degradation of beta-sheet crystals. Biomaterials (2009) 1.30
Stabilization and release of enzymes from silk films. Macromol Biosci (2010) 1.30
In vitro 3D model for human vascularized adipose tissue. Tissue Eng Part A (2009) 1.29
Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials (2009) 1.29
Stabilization of enzymes in silk films. Biomacromolecules (2009) 1.29
Effect of scaffold design on bone morphology in vitro. Tissue Eng (2006) 1.28
Activation of crystalline cellulose to cellulose III(I) results in efficient hydrolysis by cellobiohydrolase. FEBS J (2007) 1.28
Graphene-based wireless bacteria detection on tooth enamel. Nat Commun (2012) 1.28
Tissue engineering of ligaments. Annu Rev Biomed Eng (2004) 1.28
Nucleation and growth of mineralized bone matrix on silk-hydroxyapatite composite scaffolds. Biomaterials (2011) 1.28
RGD-functionalized bioengineered spider dragline silk biomaterial. Biomacromolecules (2006) 1.26