Published in Trends Biotechnol on March 25, 2008
The genome of Tetranychus urticae reveals herbivorous pest adaptations. Nature (2011) 3.29
Emerging synergy between nanotechnology and implantable biosensors: a review. Biosens Bioelectron (2009) 1.67
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci U S A (2010) 1.51
Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties. Proc Natl Acad Sci U S A (2012) 1.33
Engineering the Salmonella type III secretion system to export spider silk monomers. Mol Syst Biol (2009) 1.26
Protein-based block copolymers. Biomacromolecules (2011) 1.11
Production of self-assembling biomaterials for tissue engineering. Trends Biotechnol (2009) 1.10
Three-dimensional scaffold made from recombinant spider Silk protein for tissue engineering. Dokl Biochem Biophys (2009) 1.05
Soft tissue augmentation using silk gels: an in vitro and in vivo study. J Periodontol (2009) 1.02
Structure-function-property-design interplay in biopolymers: spider silk. Acta Biomater (2013) 1.02
Batch production of a silk-elastin-like protein in E. coli BL21(DE3): key parameters for optimisation. Microb Cell Fact (2013) 0.97
Inducing β-sheets formation in synthetic spider silk fibers by aqueous post-spin stretching. Biomacromolecules (2011) 0.96
Recombinant DNA production of spider silk proteins. Microb Biotechnol (2013) 0.96
pH-Based Regulation of Hydrogel Mechanical Properties Through Mussel-Inspired Chemistry and Processing. Adv Funct Mater (2012) 0.92
Plasticity in major ampullate silk production in relation to spider phylogeny and ecology. PLoS One (2011) 0.90
Spinning gland transcriptomics from two main clades of spiders (order: Araneae)--insights on their molecular, anatomical and behavioral evolution. PLoS One (2011) 0.89
Human corneal limbal epithelial cell response to varying silk film geometric topography in vitro. Acta Biomater (2012) 0.88
Purification and cytotoxicity of tag-free bioengineered spider silk proteins. J Biomed Mater Res A (2012) 0.87
Natural and Genetically Engineered Proteins for Tissue Engineering. Prog Polym Sci (2012) 0.87
Silk constructs for delivery of musculoskeletal therapeutics. Adv Drug Deliv Rev (2012) 0.84
Silk-based biomaterials in biomedical textiles and fiber-based implants. Adv Healthc Mater (2015) 0.84
Effects of different post-spin stretching conditions on the mechanical properties of synthetic spider silk fibers. J Mech Behav Biomed Mater (2013) 0.83
Bioinspired silicification of silica-binding peptide-silk protein chimeras: comparison of chemically and genetically produced proteins. Biomacromolecules (2012) 0.81
Silk-Its Mysteries, How It Is Made, and How It Is Used. ACS Biomater Sci Eng (2015) 0.79
Clues for biomimetics from natural composite materials. Nanomedicine (Lond) (2012) 0.78
Multifunctional spider silk polymers for gene delivery to human mesenchymal stem cells. J Biomed Mater Res B Appl Biomater (2014) 0.77
Engineered disulfides improve mechanical properties of recombinant spider silk. Protein Sci (2009) 0.77
Influence of silk-silica fusion protein design on silica condensation in vitro and cellular calcification. RSC Adv (2016) 0.77
Spider wrapping silk fibre architecture arising from its modular soluble protein precursor. Sci Rep (2015) 0.76
Low-Tech, Pilot Scale Purification of a Recombinant Spider Silk Protein Analog from Tobacco Leaves. Int J Mol Sci (2016) 0.75
The method of purifying bioengineered spider silk determines the silk sphere properties. Sci Rep (2016) 0.75
Spider Silk-CBD-Cellulose Nanocrystal Composites: Mechanism of Assembly. Int J Mol Sci (2016) 0.75
Seed-Specific Expression of Spider Silk Protein Multimers Causes Long-Term Stability. Front Plant Sci (2016) 0.75
Silk-based biomaterials. Biomaterials (2003) 7.72
Mechanism of silk processing in insects and spiders. Nature (2003) 4.85
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. Nat Mater (2010) 4.62
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
New opportunities for an ancient material. Science (2010) 3.95
Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin. Biomaterials (2005) 3.87
In vitro degradation of silk fibroin. Biomaterials (2005) 3.56
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials (2006) 3.27
Villification: how the gut gets its villi. Science (2013) 2.94
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules (2004) 2.77
Cell differentiation by mechanical stress. FASEB J (2001) 2.56
Structure and properties of silk hydrogels. Biomacromolecules (2004) 2.50
A physically transient form of silicon electronics. Science (2012) 2.47
Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol (2013) 2.32
Vascularization strategies for tissue engineering. Tissue Eng Part B Rev (2009) 2.31
Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules (2011) 2.24
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater (2010) 2.20
Electrospinning Bombyx mori silk with poly(ethylene oxide). Biomacromolecules (2002) 2.20
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Macrophage responses to silk. Biomaterials (2003) 2.04
In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials (2005) 2.02
Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials (2005) 1.94
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A (2004) 1.94
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Silk microspheres for encapsulation and controlled release. J Control Release (2006) 1.81
Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules (2008) 1.79
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J Control Release (2008) 1.72
Biomaterial films of Bombyx mori silk fibroin with poly(ethylene oxide). Biomacromolecules (2004) 1.70
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays. Proc Natl Acad Sci U S A (2009) 1.69
Twenty-one millisecond pulsars in Terzan 5 using the Green Bank Telescope. Science (2005) 1.68
Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J Biomed Mater Res A (2006) 1.68
Human bone marrow stromal cell responses on electrospun silk fibroin mats. Biomaterials (2004) 1.67
Cartilage tissue engineering with silk scaffolds and human articular chondrocytes. Biomaterials (2006) 1.67
Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Rev (2009) 1.66
Silk fibroin microtubes for blood vessel engineering. Biomaterials (2007) 1.61
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res (2010) 1.61
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Modification of silk fibroin using diazonium coupling chemistry and the effects on hMSC proliferation and differentiation. Biomaterials (2008) 1.59
Silk film biomaterials for cornea tissue engineering. Biomaterials (2008) 1.58
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials (2006) 1.56
Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed (2008) 1.55
Mapping domain structures in silks from insects and spiders related to protein assembly. J Mol Biol (2004) 1.53
Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation. PLoS One (2010) 1.52
Electrospun silk biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev (2009) 1.52
In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. Biomaterials (2008) 1.51
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci U S A (2010) 1.51
GoQBot: a caterpillar-inspired soft-bodied rolling robot. Bioinspir Biomim (2011) 1.51
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Role of adult mesenchymal stem cells in bone tissue engineering applications: current status and future prospects. Tissue Eng (2005) 1.50
Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res (2007) 1.46
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells. Tissue Eng (2006) 1.45
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Relationships between mechanical properties and extracellular matrix constituents of the cervical stroma during pregnancy. Semin Perinatol (2009) 1.42
Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules (2009) 1.42
Mechanisms of silk fibroin sol-gel transitions. J Phys Chem B (2006) 1.41
Human bone marrow stromal cell and ligament fibroblast responses on RGD-modified silk fibers. J Biomed Mater Res A (2003) 1.40
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Retracted Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. Proc Natl Acad Sci U S A (2012) 1.39
Silk materials--a road to sustainable high technology. Adv Mater (2012) 1.38
Silicon electronics on silk as a path to bioresorbable, implantable devices. Appl Phys Lett (2009) 1.38
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One (2008) 1.37
Silk-based delivery systems of bioactive molecules. Adv Drug Deliv Rev (2010) 1.37
Biomaterials derived from silk-tropoelastin protein systems. Biomaterials (2010) 1.36
Biomaterials for the development of peripheral nerve guidance conduits. Tissue Eng Part B Rev (2011) 1.35
Electrogelation for protein adhesives. Adv Mater (2010) 1.34
Silk fibroin biomaterials for controlled release drug delivery. Expert Opin Drug Deliv (2011) 1.34
Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A (2006) 1.34
Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir (2005) 1.34
Genetic engineering of fibrous proteins: spider dragline silk and collagen. Adv Drug Deliv Rev (2002) 1.33
Matrix metalloproteinases and their clinical applications in orthopaedics. Clin Orthop Relat Res (2004) 1.32
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Can tissue engineering concepts advance tumor biology research? Trends Biotechnol (2010) 1.32
Comparative chondrogenesis of human cell sources in 3D scaffolds. J Tissue Eng Regen Med (2009) 1.31
Mechanism of enzymatic degradation of beta-sheet crystals. Biomaterials (2009) 1.30
Stabilization and release of enzymes from silk films. Macromol Biosci (2010) 1.30
In vitro 3D model for human vascularized adipose tissue. Tissue Eng Part A (2009) 1.29
Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials (2009) 1.29
Stabilization of enzymes in silk films. Biomacromolecules (2009) 1.29
Effect of scaffold design on bone morphology in vitro. Tissue Eng (2006) 1.28
Graphene-based wireless bacteria detection on tooth enamel. Nat Commun (2012) 1.28
Tissue engineering of ligaments. Annu Rev Biomed Eng (2004) 1.28
Nucleation and growth of mineralized bone matrix on silk-hydroxyapatite composite scaffolds. Biomaterials (2011) 1.28
RGD-functionalized bioengineered spider dragline silk biomaterial. Biomacromolecules (2006) 1.26
In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering. Biomaterials (2005) 1.26
Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev (2010) 1.25
Concise review: Mesenchymal stem cell tumor-homing: detection methods in disease model systems. Stem Cells (2011) 1.25
Engineering custom-designed osteochondral tissue grafts. Trends Biotechnol (2008) 1.25
Gel spinning of silk tubes for tissue engineering. Biomaterials (2008) 1.24
Osteogenic differentiation of human bone marrow stromal cells on partially demineralized bone scaffolds in vitro. Tissue Eng (2004) 1.24