Published in Biomaterials on June 01, 2005
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Silk fibroin microtubes for blood vessel engineering. Biomaterials (2007) 1.61
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed (2008) 1.55
Biodegradation of silk biomaterials. Int J Mol Sci (2009) 1.55
Electrospun silk biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev (2009) 1.52
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Biological and biomechanical assessment of a long-term bioresorbable silk-derived surgical mesh in an abdominal body wall defect model. Hernia (2009) 1.39
Silicon electronics on silk as a path to bioresorbable, implantable devices. Appl Phys Lett (2009) 1.38
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. Biomacromolecules (2007) 1.37
Rheological properties of peptide-based hydrogels for biomedical and other applications. Chem Soc Rev (2010) 1.37
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Mechanism of enzymatic degradation of beta-sheet crystals. Biomaterials (2009) 1.30
Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev (2010) 1.25
Peptide-based Biopolymers in Biomedicine and Biotechnology. Mater Sci Eng R Rep (2008) 1.25
Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine. Semin Cell Dev Biol (2009) 1.21
Silk Fibroin Microfluidic Devices. Adv Mater (2007) 1.21
Non-equilibrium silk fibroin adhesives. J Struct Biol (2009) 1.20
Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells. Acta Biomater (2012) 1.18
Antiepileptic effects of silk-polymer based adenosine release in kindled rats. Exp Neurol (2009) 1.18
Lyophilized silk fibroin hydrogels for the sustained local delivery of therapeutic monoclonal antibodies. Biomaterials (2011) 1.18
Multilayered silk scaffolds for meniscus tissue engineering. Biomaterials (2010) 1.18
Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses. Biomaterials (2007) 1.17
Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies. Epilepsy Res (2009) 1.17
Biomedical applications of chemically-modified silk fibroin. J Mater Chem (2009) 1.17
The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials (2011) 1.11
Porous silk scaffolds can be used for tissue engineering annulus fibrosus. Eur Spine J (2007) 1.09
Effect of hydration on silk film material properties. Macromol Biosci (2010) 1.09
Silk fibroin encapsulated powder reservoirs for sustained release of adenosine. J Control Release (2010) 1.09
Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing. Acta Biomater (2008) 1.08
Silk coatings on PLGA and alginate microspheres for protein delivery. Biomaterials (2007) 1.06
Degradation mechanism and control of silk fibroin. Biomacromolecules (2011) 1.06
Osteoinductive silk-silica composite biomaterials for bone regeneration. Biomaterials (2010) 1.05
Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation. Biochem Pharmacol (2009) 1.03
Soft tissue augmentation using silk gels: an in vitro and in vivo study. J Periodontol (2009) 1.02
Silkworm and spider silk scaffolds for chondrocyte support. J Mater Sci Mater Med (2008) 1.02
Artificial skin--culturing of different skin cell lines for generating an artificial skin substitute on cross-weaved spider silk fibres. PLoS One (2011) 1.00
Antibiotic-Releasing Silk Biomaterials for Infection Prevention and Treatment. Adv Funct Mater (2012) 0.99
A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs. Biomaterials (2012) 0.99
Reinforcing silk scaffolds with silk particles. Macromol Biosci (2010) 0.98
Review physical and chemical aspects of stabilization of compounds in silk. Biopolymers (2012) 0.98
Clinical outcomes of silk patch in acute tympanic membrane perforation. Clin Exp Otorhinolaryngol (2015) 0.95
Charge-Tunable Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Adv Funct Mater (2013) 0.95
Silk-based biomaterials for sustained drug delivery. J Control Release (2014) 0.94
Adipogenic differentiation of human adipose-derived stem cells on 3D silk scaffolds. Methods Mol Biol (2011) 0.92
Mechanisms of controlled release from silk fibroin films. Biomacromolecules (2011) 0.91
Cytocompatibility of regenerated silk fibroin film: a medical biomaterial applicable to wound healing. J Zhejiang Univ Sci B (2010) 0.90
Fabrication and intermolecular interactions of silk fibroin/hydroxybutyl chitosan blended nanofibers. Int J Mol Sci (2011) 0.90
Sustainable three-dimensional tissue model of human adipose tissue. Tissue Eng Part C Methods (2013) 0.90
Influence of post-treatment with 75% (v/v) ethanol vapor on the properties of SF/P(LLA-CL) nanofibrous scaffolds. Int J Mol Sci (2012) 0.87
Silk fibroin protein from mulberry and non-mulberry silkworms: cytotoxicity, biocompatibility and kinetics of L929 murine fibroblast adhesion. J Mater Sci Mater Med (2008) 0.87
A silk hydrogel-based delivery system of bone morphogenetic protein for the treatment of large bone defects. J Mech Behav Biomed Mater (2011) 0.87
Silk fibroin and polyethylene glycol-based biocompatible tissue adhesives. J Biomed Mater Res A (2011) 0.87
Slowly degradable porous silk microfabricated scaffolds for vascularized tissue formation. Adv Funct Mater (2013) 0.87
Remodeling of tissue-engineered bone structures in vivo. Eur J Pharm Biopharm (2013) 0.87
Preparation of double-raschel knitted silk vascular grafts and evaluation of short-term function in a rat abdominal aorta. J Artif Organs (2011) 0.87
Impact of silk biomaterial structure on proteolysis. Acta Biomater (2014) 0.86
Stem cell-based meniscus tissue engineering. Tissue Eng Part A (2011) 0.86
Accelerated In Vitro Degradation of Optically Clear Low β-Sheet Silk Films by Enzyme-Mediated Pretreatment. Transl Vis Sci Technol (2013) 0.85
Production of silk sericin/silk fibroin blend nanofibers. Nanoscale Res Lett (2011) 0.85
Mechanisms of monoclonal antibody stabilization and release from silk biomaterials. Biomaterials (2013) 0.85
Human stem cell neuronal differentiation on silk-carbon nanotube composite. Nanoscale Res Lett (2012) 0.85
Silk constructs for delivery of musculoskeletal therapeutics. Adv Drug Deliv Rev (2012) 0.84
A 12-month Survey of Early Use and Surgeon Satisfaction with a New Highly Purified Silk Matrix: SERI Surgical Scaffold. Plast Reconstr Surg Glob Open (2014) 0.84
A shape memory stent of poly(ε-caprolactone-co-DL-lactide) copolymer for potential treatment of esophageal stenosis. J Mater Sci Mater Med (2011) 0.84
Silk-based biomaterials in biomedical textiles and fiber-based implants. Adv Healthc Mater (2015) 0.84
Stimulus-responsive hydrogels: Theory, modern advances, and applications. Mater Sci Eng R Rep (2015) 0.83
Mechanisms of enzymatic degradation of amyloid Beta microfibrils generating nanofilaments and nanospheres related to cytotoxicity. Biochemistry (2010) 0.83
Arrayed Hollow Channels in Silk-based Scaffolds Provide Functional Outcomes for Engineering Critically-sized Tissue Constructs. Adv Funct Mater (2014) 0.83
Influence of the mechanical environment on the engineering of mineralised tissues using human dental pulp stem cells and silk fibroin scaffolds. PLoS One (2014) 0.82
Incorporation of proteinase inhibitors into silk-based delivery devices for enhanced control of degradation and drug release. Biomaterials (2010) 0.82
Silk fibroin-based nanoparticles for drug delivery. Int J Mol Sci (2015) 0.81
Multiple silk coatings on biphasic calcium phosphate scaffolds: effect on physical and mechanical properties and in vitro osteogenic response of human mesenchymal stem cells. Biomacromolecules (2013) 0.80
Multifunctionalized electrospun silk fibers promote axon regeneration in central nervous system. Adv Funct Mater (2011) 0.80
Effect of silk protein processing on drug delivery from silk films. Macromol Biosci (2013) 0.80
Static axial stretching enhances the mechanical properties and cellular responses of fibrin microthreads. Acta Biomater (2014) 0.79
In vivo bioresponses to silk proteins. Biomaterials (2015) 0.79
A model for the stretch-mediated enzymatic degradation of silk fibers. J Mech Behav Biomed Mater (2010) 0.79
Film-based Implants for Supporting Neuron-Electrode Integrated Interfaces for The Brain. Adv Funct Mater (2014) 0.79
Different Types of Peptide Detected by Mass Spectrometry among Fresh Silk and Archaeological Silk Remains for Distinguishing Modern Contamination. PLoS One (2015) 0.79
Clinical application of a silk fibroin protein biologic scaffold for abdominal wall fascial reinforcement. Plast Reconstr Surg Glob Open (2014) 0.78
Injectable silk-based biomaterials for cervical tissue augmentation: an in vitro study. Am J Obstet Gynecol (2015) 0.78
Stability of silk and collagen protein materials in space. Sci Rep (2013) 0.77
Structure and biodegradation mechanism of milled Bombyx mori silk particles. Biomacromolecules (2012) 0.77
An antibacterial and absorbable silk-based fixation material with impressive mechanical properties and biocompatibility. Sci Rep (2016) 0.77
Will silk fibroin nanofiber scaffolds ever hold a useful place in Translational Regenerative Medicine? Int J Burns Trauma (2011) 0.76
Cell proliferation by silk gut incorporating FGF-2 protein microcrystals. Sci Rep (2015) 0.76
Development of a silk and collagen fiber scaffold for anterior cruciate ligament reconstruction. J Mater Sci Mater Med (2012) 0.76
Accelerated in vitro degradation of optically clear low-β sheet silk films by enzyme-mediated pretreatment. JAMA Ophthalmol (2013) 0.75
Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. Int J Pharm (2015) 0.75
Characterization of Silk Fibroin/Chitosan 3D Porous Scaffold and In Vitro Cytology. PLoS One (2015) 0.75
Effect of β-sheet crystalline content on mass transfer in silk films. J Memb Sci (2011) 0.75
Adenosine-associated delivery systems. J Drug Target (2015) 0.75
microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A (2006) 8.24
Silk-based biomaterials. Biomaterials (2003) 7.72
Mechanism of silk processing in insects and spiders. Nature (2003) 4.85
Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proc Natl Acad Sci U S A (2008) 4.79
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. Nat Mater (2010) 4.62
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
New opportunities for an ancient material. Science (2010) 3.95
miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol Ther (2007) 3.93
Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin. Biomaterials (2005) 3.87
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials (2006) 3.27
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Villification: how the gut gets its villi. Science (2013) 2.94
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules (2004) 2.77
Cell differentiation by mechanical stress. FASEB J (2001) 2.56
Structure and properties of silk hydrogels. Biomacromolecules (2004) 2.50
Exome sequencing of a multigenerational human pedigree. PLoS One (2009) 2.48
A physically transient form of silicon electronics. Science (2012) 2.47
Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol (2013) 2.32
Vascularization strategies for tissue engineering. Tissue Eng Part B Rev (2009) 2.31
Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules (2011) 2.24
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater (2010) 2.20
Electrospinning Bombyx mori silk with poly(ethylene oxide). Biomacromolecules (2002) 2.20
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Exome sequencing allows for rapid gene identification in a Charcot-Marie-Tooth family. Ann Neurol (2011) 2.09
Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol (2010) 2.08
Macrophage responses to silk. Biomaterials (2003) 2.04
In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials (2005) 2.02
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials (2005) 1.94
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A (2004) 1.94
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Silk microspheres for encapsulation and controlled release. J Control Release (2006) 1.81
Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization. Cancer Res (2005) 1.80
Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules (2008) 1.79
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J Control Release (2008) 1.72
Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma. Cancer Res (2006) 1.70
Biomaterial films of Bombyx mori silk fibroin with poly(ethylene oxide). Biomacromolecules (2004) 1.70
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays. Proc Natl Acad Sci U S A (2009) 1.69
Twenty-one millisecond pulsars in Terzan 5 using the Green Bank Telescope. Science (2005) 1.68
Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J Biomed Mater Res A (2006) 1.68
Human bone marrow stromal cell responses on electrospun silk fibroin mats. Biomaterials (2004) 1.67
Cartilage tissue engineering with silk scaffolds and human articular chondrocytes. Biomaterials (2006) 1.67
Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Rev (2009) 1.66
Silk fibroin microtubes for blood vessel engineering. Biomaterials (2007) 1.61
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res (2010) 1.61
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Modification of silk fibroin using diazonium coupling chemistry and the effects on hMSC proliferation and differentiation. Biomaterials (2008) 1.59
Bone morphogenetic protein-2 decorated silk fibroin films induce osteogenic differentiation of human bone marrow stromal cells. J Biomed Mater Res A (2004) 1.59
Silk film biomaterials for cornea tissue engineering. Biomaterials (2008) 1.58
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials (2006) 1.56
Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed (2008) 1.55
Mapping domain structures in silks from insects and spiders related to protein assembly. J Mol Biol (2004) 1.53
Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation. PLoS One (2010) 1.52
Electrospun silk biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev (2009) 1.52
In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. Biomaterials (2008) 1.51
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci U S A (2010) 1.51
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Role of adult mesenchymal stem cells in bone tissue engineering applications: current status and future prospects. Tissue Eng (2005) 1.50
Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer. Clin Cancer Res (2007) 1.48
Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res (2007) 1.46
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells. Tissue Eng (2006) 1.45
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Relationships between mechanical properties and extracellular matrix constituents of the cervical stroma during pregnancy. Semin Perinatol (2009) 1.42
Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules (2009) 1.42
Mechanisms of silk fibroin sol-gel transitions. J Phys Chem B (2006) 1.41
Human bone marrow stromal cell and ligament fibroblast responses on RGD-modified silk fibers. J Biomed Mater Res A (2003) 1.40
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Timing of granulocyte-colony stimulating factor treatment after acute myocardial infarction and recovery of left ventricular function: results from the STEMMI trial. Int J Cardiol (2009) 1.39
Retracted Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. Proc Natl Acad Sci U S A (2012) 1.39
Silk materials--a road to sustainable high technology. Adv Mater (2012) 1.38
Silicon electronics on silk as a path to bioresorbable, implantable devices. Appl Phys Lett (2009) 1.38
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One (2008) 1.37
Spider silks and their applications. Trends Biotechnol (2008) 1.37
Transcriptional coactivator Drosophila eyes absent homologue 2 is up-regulated in epithelial ovarian cancer and promotes tumor growth. Cancer Res (2005) 1.37
Silk-based delivery systems of bioactive molecules. Adv Drug Deliv Rev (2010) 1.37
Biomaterials derived from silk-tropoelastin protein systems. Biomaterials (2010) 1.36
Biomaterials for the development of peripheral nerve guidance conduits. Tissue Eng Part B Rev (2011) 1.35
Electrogelation for protein adhesives. Adv Mater (2010) 1.34
Silk fibroin biomaterials for controlled release drug delivery. Expert Opin Drug Deliv (2011) 1.34
Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A (2006) 1.34
Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir (2005) 1.34
Genetic engineering of fibrous proteins: spider dragline silk and collagen. Adv Drug Deliv Rev (2002) 1.33