Published in Xenotransplantation on January 01, 2005
B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months. Am J Transplant (2011) 1.51
Genetic manipulation in pigs. Curr Opin Organ Transplant (2009) 0.90
Xenotransplantation as a model of integrated, multidisciplinary research. Organogenesis (2009) 0.86
Clinical xenotransplantation of organs: why aren't we there yet? PLoS Med (2007) 0.81
Cell engineering and molecular pharming for biopharmaceuticals. Open Med Chem J (2008) 0.75
The structure of haplotype blocks in the human genome. Science (2002) 50.88
Gene expression patterns in human liver cancers. Mol Biol Cell (2002) 6.93
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity (2010) 3.88
A transcriptional profile of aging in the human kidney. PLoS Biol (2004) 3.69
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation. J Pharmacol Exp Ther (2006) 3.46
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science (2003) 3.19
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates. Nat Med (2006) 2.83
Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation (2013) 2.55
Clinical trial of islet xenotransplantation in Mexico. Xenotransplantation (2006) 2.51
Concern Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest (2012) 2.23
Oxysterols direct immune cell migration via EBI2. Nature (2011) 2.19
Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs. Anesthesiology (2014) 2.06
Prolonged survival of porcine hepatocytes in cynomolgus monkeys. Gastroenterology (2006) 2.04
Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat. J Mol Cell Cardiol (2006) 1.99
Sudden cardiac death in the soccer field: a retrospective study in young soccer players from 2000 to 2013. Phys Sportsmed (2014) 1.98
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56
Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol (2005) 1.54
Sotrastaurin (AEB071) alone and in combination with cyclosporine A prolongs survival times of non-human primate recipients of life-supporting kidney allografts. Transplantation (2012) 1.54
Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine. J Virol (2002) 1.53
Host-derived circulating cells do not significantly contribute to cardiac regeneration in heterotopic rat heart transplants. Cardiovasc Res (2005) 1.48
Heterotopic cardiac xenotransplantation in rodents: report of a refined technique in a hamster-to-rat model. Microsurgery (2005) 1.47
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus. Arthritis Rheum (2008) 1.44
Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet (2002) 1.41
Increase in interleukin-1beta in late-life depression. Am J Psychiatry (2005) 1.40
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36
Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature Swine. J Virol (2004) 1.35
Identification of heat shock protein 60 as the ligand on Histoplasma capsulatum that mediates binding to CD18 receptors on human macrophages. J Immunol (2003) 1.31
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. PLoS Genet (2009) 1.30
The PKC inhibitor AEB071 may be a therapeutic option for psoriasis. J Clin Invest (2008) 1.27
Consequences of delayed pump infusion line change in patients with type 1 diabetes mellitus treated with continuous subcutaneous insulin infusion. J Diabetes Complications (2009) 1.26
Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons. Xenotransplantation (2004) 1.26
The streptozotocin-induced diabetic nude mouse model: differences between animals from different sources. Comp Med (2011) 1.23
HPLC-atmospheric pressure chemical ionization MS/MS for quantification of 15-F2t-isoprostane in human urine and plasma. Clin Chem (2007) 1.22
Biochemical mechanisms of cyclosporine neurotoxicity. Mol Interv (2004) 1.19
Novel endothelial cell markers in hepatocellular carcinoma. Mod Pathol (2004) 1.18
Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen. Am J Transplant (2004) 1.17
Metabolism of fostamatinib, the oral methylene phosphate prodrug of the spleen tyrosine kinase inhibitor R406 in humans: contribution of hepatic and gut bacterial processes to the overall biotransformation. Drug Metab Dispos (2010) 1.17
Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod Pathol (2006) 1.12
Cyclosporine pharmacokinetics and dosing modifications in human immunodeficiency virus-infected liver and kidney transplant recipients. Transplantation (2005) 1.10
Irradiation alters selection for oncogenic mutations in hematopoietic progenitors. Cancer Res (2009) 1.09
Absence of replication-competent human-tropic porcine endogenous retroviruses in the germ line DNA of inbred miniature Swine. J Virol (2004) 1.09
Development and validation of an assay for the quantification of 11 nucleotides using LC/LC-electrospray ionization-MS. Anal Biochem (2007) 1.09
Maintenance triple immunosuppression with cyclosporin A, mycophenolate sodium and steroids allows prolonged survival of primate recipients of hDAF porcine renal xenografts. Xenotransplantation (2003) 1.06
Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs. FASEB J (2004) 1.04
Progress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literature. Xenotransplantation (2014) 1.04
Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates. Transplantation (2005) 1.04
Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4. J Pharmacol Exp Ther (2002) 1.04
Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells. Br J Pharmacol (2009) 1.04
Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice. Arthritis Rheum (2010) 1.03
Cardiac interstitial cells express GATA4 and control dedifferentiation and cell cycle re-entry of adult cardiomyocytes. J Mol Cell Cardiol (2008) 1.03
Single dose of glutamine enhances myocardial tissue metabolism, glutathione content, and improves myocardial function after ischemia-reperfusion injury. JPEN J Parenter Enteral Nutr (2003) 1.01
Coagulation cascade activation triggers early failure of pig hearts expressing human complement regulatory genes. Xenotransplantation (2007) 1.01
Ultrasound-induced mild hyperthermia as a novel approach to increase drug uptake in brain microvessel endothelial cells. Pharm Res (2002) 1.00
Effects of lovastatin on breast cancer cells: a proteo-metabonomic study. Breast Cancer Res (2010) 1.00
Anti-non-Gal porcine endothelial cell antibodies in acute humoral xenograft rejection of hDAF-transgenic porcine hearts in cynomolgus monkeys. Xenotransplantation (2004) 0.99
Elicited antibodies in baboons exposed to tissues from alpha1,3-galactosyltransferase gene-knockout pigs. Transplantation (2006) 0.99
Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy. Cardiovasc Res (2012) 0.99
Co-stimulation blockade targeting CD154 and CD28/B7 modulates the induced antibody response after a pig-to-baboon cardiac xenograft. Xenotransplantation (2005) 0.99
CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam. J Pharmacol Exp Ther (2003) 0.99
Cyclosporine induces endothelial cell release of complement-activating microparticles. J Am Soc Nephrol (2013) 0.99
Enhanced induction of telomerase-specific CD4(+) T cells using dendritic cells transfected with RNA encoding a chimeric gene product. Cancer Res (2002) 0.98
Pharmacokinetics of mycophenolate mofetil and sirolimus in children. Ther Drug Monit (2008) 0.98
In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells. Stem Cell Rev (2011) 0.97
Gene capture by Helitron transposons reshuffles the transcriptome of maize. Genetics (2011) 0.97
Pharmacokinetic interactions between cyclosporine and protease inhibitors in HIV+ subjects. Drug Metab Pharmacokinet (2003) 0.97
Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts. J Immunol (2013) 0.96
Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing. Birth Defects Res A Clin Mol Teratol (2009) 0.96
Species incompatibilities in the pig-to-macaque islet xenotransplant model affect transplant outcome: a comparison with allotransplantation. Xenotransplantation (2011) 0.96
Greater free plasma VEGF and lower soluble VEGF receptor-1 in acute mountain sickness. J Appl Physiol (1985) (2005) 0.95
Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection. Xenotransplantation (2011) 0.95
Life-supporting function of genetically modified swine lungs in baboons. J Thorac Cardiovasc Surg (2007) 0.94
Human macrophages do not require phagosome acidification to mediate fungistatic/fungicidal activity against Histoplasma capsulatum. J Immunol (2006) 0.94
Intracerebral xenotransplantation: recent findings and perspectives for local immunosuppression. Curr Opin Organ Transplant (2011) 0.94
Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation. Nephron Exp Nephrol (2009) 0.94
alpha1,3-Galactosyltransferase gene-knockout miniature swine produce natural cytotoxic anti-Gal antibodies. Transplantation (2004) 0.94
In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates. J Heart Lung Transplant (2003) 0.93
Incidence of hyperacute rejection in pig-to-primate transplantation using organs from hDAF-transgenic donors. Transplantation (2002) 0.93
Humoral immunity and antibody-mediated rejection in solid organ transplantation. Semin Immunol (2011) 0.92
A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem (2011) 0.92
Genotyping of porcine endogenous retroviruses from a family of miniature swine. J Virol (2004) 0.92
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-- executive summary. Xenotransplantation (2009) 0.92
Association of bleeding and thrombosis with outcome in extracorporeal life support. Pediatr Crit Care Med (2015) 0.92
Polymer-free biolimus a9-coated stent demonstrates more sustained intimal inhibition, improved healing, and reduced inflammation compared with a polymer-coated sirolimus-eluting cypher stent in a porcine model. Circ Cardiovasc Interv (2010) 0.91
Quantification of 15-F2t-isoprostane in human plasma and urine: results from enzyme-linked immunoassay and liquid chromatography/tandem mass spectrometry cannot be compared. Rapid Commun Mass Spectrom (2011) 0.90
Interpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes. Mol Cancer Ther (2011) 0.90