| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Cameroonian medicinal plants: pharmacology and derived natural products.
|
Front Pharmacol
|
2010
|
1.80
|
|
2
|
Chemotherapy-induced resistance by ATP-binding cassette transporter genes.
|
Biochim Biophys Acta
|
2007
|
1.79
|
|
3
|
Molecular principles of cancer invasion and metastasis (review).
|
Int J Oncol
|
2009
|
1.66
|
|
4
|
Evidence-based Chinese medicine for cancer therapy.
|
J Ethnopharmacol
|
2007
|
1.47
|
|
5
|
Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts.
|
J Ethnopharmacol
|
2011
|
1.46
|
|
6
|
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.
|
J Biol Chem
|
2010
|
1.41
|
|
7
|
Antimicrobial activity of clove and rosemary essential oils alone and in combination.
|
Phytother Res
|
2007
|
1.39
|
|
8
|
Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes.
|
Cancer Res
|
2004
|
1.32
|
|
9
|
Artesunate derived from traditional Chinese medicine induces DNA damage and repair.
|
Cancer Res
|
2008
|
1.31
|
|
10
|
Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate.
|
Biochem Pharmacol
|
2004
|
1.28
|
|
11
|
Modulation of human BCRP (ABCG2) activity by anti-HIV drugs.
|
J Antimicrob Chemother
|
2007
|
1.27
|
|
12
|
A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
|
Oncotarget
|
2013
|
1.27
|
|
13
|
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
|
Clin Infect Dis
|
2008
|
1.23
|
|
14
|
Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation.
|
Methods
|
2002
|
1.21
|
|
15
|
Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components.
|
Molecules
|
2012
|
1.20
|
|
16
|
Artesunate in the treatment of metastatic uveal melanoma--first experiences.
|
Oncol Rep
|
2005
|
1.19
|
|
17
|
The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.
|
Antiviral Res
|
2005
|
1.14
|
|
18
|
Leishmaniasis: drug resistance and natural products (review).
|
Int J Mol Med
|
2008
|
1.13
|
|
19
|
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants.
|
PLoS One
|
2011
|
1.12
|
|
20
|
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia.
|
Clin Cancer Res
|
2006
|
1.11
|
|
21
|
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system.
|
Antiviral Res
|
2005
|
1.10
|
|
22
|
Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells.
|
Mol Cancer Ther
|
2011
|
1.10
|
|
23
|
Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV).
|
Planta Med
|
2006
|
1.09
|
|
24
|
Polo-like kinase 1 as target for cancer therapy.
|
Exp Hematol Oncol
|
2012
|
1.09
|
|
25
|
Molecular biology of cantharidin in cancer cells.
|
Chin Med
|
2007
|
1.08
|
|
26
|
Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition.
|
J Biol Chem
|
2012
|
1.08
|
|
27
|
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.
|
Int J Cancer
|
2010
|
1.07
|
|
28
|
Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate.
|
PLoS One
|
2007
|
1.06
|
|
29
|
Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities.
|
J Ethnopharmacol
|
2010
|
1.06
|
|
30
|
Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum.
|
Biochem Pharmacol
|
2012
|
1.05
|
|
31
|
Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense.
|
J Ethnopharmacol
|
2013
|
1.04
|
|
32
|
MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60.
|
Cancer Genomics Proteomics
|
2010
|
1.04
|
|
33
|
Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma.
|
Anticancer Res
|
2011
|
1.04
|
|
34
|
Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.
|
Evid Based Complement Alternat Med
|
2012
|
1.02
|
|
35
|
Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway.
|
Chem Biol Interact
|
2010
|
1.02
|
|
36
|
Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells.
|
Nitric Oxide
|
2008
|
1.02
|
|
37
|
Drug resistance in Plasmodium: natural products in the fight against malaria.
|
Mini Rev Med Chem
|
2009
|
1.00
|
|
38
|
Therapeutic and diagnostic applications of nanoparticles.
|
Curr Drug Targets
|
2011
|
1.00
|
|
39
|
Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Treatment of human African trypanosomiasis with natural products (Review).
|
Int J Mol Med
|
2008
|
0.98
|
|
40
|
Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy.
|
J Ethnopharmacol
|
2011
|
0.98
|
|
41
|
Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients.
|
Clin Cancer Res
|
2002
|
0.97
|
|
42
|
First study of oral Artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markers.
|
Anticancer Res
|
2011
|
0.97
|
|
43
|
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo.
|
BMC Cancer
|
2006
|
0.95
|
|
44
|
Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from Geranium sibiricum L.
|
J Agric Food Chem
|
2010
|
0.95
|
|
45
|
P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs.
|
J Ethnopharmacol
|
2011
|
0.95
|
|
46
|
Cytotoxicity and Modes of Action of the Methanol Extracts of Six Cameroonian Medicinal Plants against Multidrug-Resistant Tumor Cells.
|
Evid Based Complement Alternat Med
|
2013
|
0.95
|
|
47
|
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.
|
Radiother Oncol
|
2012
|
0.94
|
|
48
|
Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol.
|
Planta Med
|
2011
|
0.93
|
|
49
|
Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity.
|
Bioresour Technol
|
2009
|
0.93
|
|
50
|
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol.
|
Phytomedicine
|
2013
|
0.93
|
|
51
|
Optimization of luteolin separation from pigeonpea [Cajanus cajan (L.) Millsp.] leaves by macroporous resins.
|
J Chromatogr A
|
2006
|
0.92
|
|
52
|
Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells.
|
Biochem Pharmacol
|
2009
|
0.92
|
|
53
|
Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.
|
Antiviral Res
|
2011
|
0.91
|
|
54
|
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.
|
Genes Chromosomes Cancer
|
2005
|
0.91
|
|
55
|
Molecular mechanisms underlying St. John's wort drug interactions.
|
Curr Drug Metab
|
2008
|
0.91
|
|
56
|
Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.
|
Molecules
|
2010
|
0.91
|
|
57
|
Review. Drug resistance of human immunodeficiency virus and overcoming it by natural products.
|
In Vivo
|
2009
|
0.91
|
|
58
|
Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.
|
Planta Med
|
2007
|
0.91
|
|
59
|
Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms.
|
J Ethnopharmacol
|
2012
|
0.91
|
|
60
|
Fighting cancer with red wine? Molecular mechanisms of resveratrol.
|
Crit Rev Food Sci Nutr
|
2009
|
0.90
|
|
61
|
Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.
|
Lung Cancer
|
2012
|
0.89
|
|
62
|
Herpes simplex virus: Drug resistance and new treatment options using natural products (Review).
|
Mol Med Rep
|
2011
|
0.89
|
|
63
|
Natural products as promising drug candidates for the treatment of hepatitis B and C.
|
Acta Pharmacol Sin
|
2008
|
0.88
|
|
64
|
Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?
|
Evid Based Complement Alternat Med
|
2013
|
0.88
|
|
65
|
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
|
PLoS One
|
2011
|
0.88
|
|
66
|
Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.
|
Curr Drug Discov Technol
|
2010
|
0.88
|
|
67
|
Cancer therapy with natural products and medicinal plants.
|
Planta Med
|
2010
|
0.88
|
|
68
|
Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.
|
Cancer Genomics Proteomics
|
2010
|
0.88
|
|
69
|
Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.
|
Molecules
|
2010
|
0.87
|
|
70
|
Berberine inhibits cell growth and mediates caspase-independent cell death in human pancreatic cancer cells.
|
Planta Med
|
2010
|
0.87
|
|
71
|
Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway.
|
J Agric Food Chem
|
2013
|
0.87
|
|
72
|
Safety and efficacy field study of artesunate for dogs with non-resectable tumours.
|
Anticancer Res
|
2013
|
0.87
|
|
73
|
Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC-MS.
|
J Sep Sci
|
2008
|
0.87
|
|
74
|
A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner.
|
J Ethnopharmacol
|
2010
|
0.86
|
|
75
|
Anti-cancer natural product library from traditional chinese medicine.
|
Comb Chem High Throughput Screen
|
2008
|
0.86
|
|
76
|
Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.
|
J Ethnopharmacol
|
2012
|
0.86
|
|
77
|
In vitro antioxidant and antimicrobial activity of extracts from Morus alba L. leaves, stems and fruits.
|
Am J Chin Med
|
2012
|
0.86
|
|
78
|
Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells.
|
Invest New Drugs
|
2014
|
0.86
|
|
79
|
Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis.
|
Clin Cancer Res
|
2006
|
0.86
|
|
80
|
Activity of novel plant extracts against medullary thyroid carcinoma cells.
|
Anticancer Res
|
2004
|
0.86
|
|
81
|
Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae).
|
J Pharm Pharmacol
|
2009
|
0.86
|
|
82
|
Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines.
|
J Neurosurg
|
2004
|
0.85
|
|
83
|
Three-dimensional modeling of glucose-6-phosphate dehydrogenase-deficient variants from German ancestry.
|
PLoS One
|
2007
|
0.85
|
|
84
|
Activity investigation of pinostrobin towards herpes simplex virus-1 as determined by atomic force microscopy.
|
Phytomedicine
|
2010
|
0.84
|
|
85
|
Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine.
|
Cancer Genomics Proteomics
|
2010
|
0.84
|
|
86
|
Phytomedicine in otorhinolaryngology and pulmonology: clinical trials with herbal remedies.
|
Pharmaceuticals (Basel)
|
2012
|
0.84
|
|
87
|
Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer.
|
Biochimie
|
2011
|
0.83
|
|
88
|
Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: a feasibility study.
|
Zhong Xi Yi Jie He Xue Bao
|
2012
|
0.83
|
|
89
|
Polyhydroxylated steroidal glycosides from Paris polyphylla.
|
J Nat Prod
|
2012
|
0.83
|
|
90
|
In vitro antioxidant properties, DNA damage protective activity, and xanthine oxidase inhibitory effect of cajaninstilbene acid, a stilbene compound derived from pigeon pea [Cajanus cajan (L.) Millsp.] leaves.
|
J Agric Food Chem
|
2010
|
0.82
|
|
91
|
Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis.
|
Bioorg Med Chem
|
2013
|
0.82
|
|
92
|
Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells.
|
BMC Complement Altern Med
|
2013
|
0.82
|
|
93
|
Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel.
|
Int J Oncol
|
2008
|
0.82
|
|
94
|
Microarray-based mRNA expression profiling of leukemia cells treated with the flavonoid, casticin.
|
Cancer Genomics Proteomics
|
2012
|
0.82
|
|
95
|
Antibacterial activity and cytotoxicity of selected Egyptian medicinal plants.
|
Planta Med
|
2011
|
0.82
|
|
96
|
Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy.
|
Planta Med
|
2007
|
0.82
|
|
97
|
EGFR but not PDGFR-beta expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines.
|
Anticancer Res
|
2003
|
0.82
|
|
98
|
Role of transporter genes in cisplatin resistance.
|
In Vivo
|
2008
|
0.82
|
|
99
|
The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.
|
Curr Cancer Drug Targets
|
2009
|
0.82
|
|
100
|
Separation of 7-xylosyl-10-deacetyl paclitaxel and 10-deacetylbaccatin III from the remainder extracts free of paclitaxel using macroporous resins.
|
J Chromatogr A
|
2007
|
0.82
|
|
101
|
Antiangiogenic activity and pharmacogenomics of medicinal plants from traditional korean medicine.
|
Evid Based Complement Alternat Med
|
2013
|
0.82
|
|
102
|
Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells.
|
J Med Chem
|
2010
|
0.82
|
|
103
|
Nobel Prize for artemisinin brings phytotherapy into the spotlight.
|
Phytomedicine
|
2015
|
0.81
|
|
104
|
Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms.
|
Int J Mol Med
|
2005
|
0.81
|
|
105
|
Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine.
|
Biochem Pharmacol
|
2011
|
0.81
|
|
106
|
Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine.
|
Planta Med
|
2010
|
0.81
|
|
107
|
Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells.
|
Eur J Pharmacol
|
2010
|
0.81
|
|
108
|
Effect of artesunate on immune cells in ret-transgenic mouse melanoma model.
|
Anticancer Drugs
|
2009
|
0.81
|
|
109
|
UV-induced changes of active components and antioxidant activity in postharvest pigeon pea [Cajanus cajan (L.) Millsp.] leaves.
|
J Agric Food Chem
|
2013
|
0.81
|
|
110
|
Determination and quantification of astragalosides in Radix Astragali and its medicinal products using LC-MS.
|
J Sep Sci
|
2009
|
0.81
|
|
111
|
Integration of Different "-omics" Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells.
|
Evid Based Complement Alternat Med
|
2013
|
0.81
|
|
112
|
Determination of paclitaxel and its analogues in the needles of Taxus species by using negative pressure cavitation extraction followed by HPLC-MS-MS.
|
J Sep Sci
|
2009
|
0.80
|
|
113
|
Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics.
|
Methods
|
2012
|
0.80
|
|
114
|
Inhibition of epidermal growth factor receptor over-expressing cancer cells by the aphorphine-type isoquinoline alkaloid, dicentrine.
|
Biochem Pharmacol
|
2009
|
0.80
|
|
115
|
Factors determining sensitivity or resistance of tumor cell lines towards artesunate.
|
Chem Biol Interact
|
2010
|
0.80
|
|
116
|
Fighting mycobacterial infections by antibiotics, phytochemicals and vaccines.
|
Microbes Infect
|
2010
|
0.80
|
|
117
|
The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein--a well-known, yet poorly understood drug transporter.
|
Invest New Drugs
|
2014
|
0.80
|
|
118
|
Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas.
|
Arch Med Res
|
2004
|
0.80
|
|
119
|
Aptamers as a novel tool for diagnostics and therapy.
|
Invest New Drugs
|
2015
|
0.80
|
|
120
|
Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway.
|
Chem Biol Interact
|
2012
|
0.80
|
|
121
|
Inhibition of epidermal growth factor receptor-overexpressing cancer cells by camptothecin, 20-(N,N-diethyl) glycinate.
|
Biochem Pharmacol
|
2010
|
0.80
|
|
122
|
Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway.
|
Chem Biol Interact
|
2012
|
0.80
|
|
123
|
Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate.
|
Int J Oncol
|
2009
|
0.79
|
|
124
|
Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, guieranone A.
|
Cell Div
|
2012
|
0.79
|
|
125
|
Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells.
|
Front Neurosci
|
2013
|
0.79
|
|
126
|
Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells.
|
Invest New Drugs
|
2015
|
0.79
|
|
127
|
Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi.
|
Planta Med
|
2006
|
0.79
|
|
128
|
Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives.
|
J Nutr Biochem
|
2011
|
0.79
|
|
129
|
Inhibition of inducible nitric oxide synthase by bis(helenalinyl)glutarate in RAW264.7 macrophages.
|
Biochem Pharmacol
|
2010
|
0.79
|
|
130
|
Genomic imbalances in T-cell acute lymphoblastic leukemia cell lines.
|
Int J Oncol
|
2002
|
0.79
|
|
131
|
Cytotoxic activity of curcumin towards CCRF-CEM leukemia cells and its effect on DNA damage.
|
Molecules
|
2009
|
0.79
|
|
132
|
Effects of Scrophularia ningpoensis Hemsl. on Inhibition of Proliferation, Apoptosis Induction and NF-κB Signaling of Immortalized and Cancer Cell Lines.
|
Pharmaceuticals (Basel)
|
2012
|
0.79
|
|
133
|
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells.
|
Toxicol Appl Pharmacol
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2012
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