Published in Cancer Res on December 15, 2004
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance. Proc Natl Acad Sci U S A (2011) 1.97
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database. Mol Cancer Ther (2009) 1.83
Identification and pathway analysis of microRNAs with no previous involvement in breast cancer. PLoS One (2012) 1.57
APC selectively mediates response to chemotherapeutic agents in breast cancer. BMC Cancer (2015) 1.39
Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2007) 1.19
Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites. Eukaryot Cell (2006) 1.09
Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate. PLoS One (2007) 1.06
SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes. PLoS One (2011) 1.01
Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resist Updat (2012) 1.01
Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer. Curr Pharm Biotechnol (2011) 1.01
Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents. Front Microbiol (2012) 0.98
Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins. Cancer Res (2009) 0.97
Cytotoxicity and Modes of Action of the Methanol Extracts of Six Cameroonian Medicinal Plants against Multidrug-Resistant Tumor Cells. Evid Based Complement Alternat Med (2013) 0.95
A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration. Blood (2008) 0.91
Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells. Invest New Drugs (2014) 0.86
Targeting mitochondrial cell death pathway to overcome drug resistance with a newly developed iron chelate. PLoS One (2010) 0.86
Mitochondrial ABC transporters function: the role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species. Biochim Biophys Acta (2012) 0.84
Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells. BMC Complement Altern Med (2015) 0.83
Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells. BMC Complement Altern Med (2013) 0.82
The role of ATP-binding cassette transporter A2 in childhood acute lymphoblastic leukemia multidrug resistance. Iran J Ped Hematol Oncol (2014) 0.80
Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells. Invest New Drugs (2015) 0.79
Transport processes of radiopharmaceuticals and -modulators. Radiat Oncol (2011) 0.78
Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties. J Cell Mol Med (2010) 0.78
Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines. BMC Complement Altern Med (2014) 0.78
Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance. Pharmaceuticals (Basel) (2016) 0.78
Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8. Mol Genet Genomics (2010) 0.77
Factors determining sensitivity and resistance of tumor cells to arsenic trioxide. PLoS One (2012) 0.77
A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells. BMC Complement Altern Med (2013) 0.76
RhoA regulates resistance to irinotecan by regulating membrane transporter and apoptosis signaling in colorectal cancer. Oncotarget (2016) 0.75
Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines. BMC Complement Altern Med (2016) 0.75
Analysis of expression of drug resistance-linked ABC transporters in cancer cells by quantitative RT-PCR. Methods Mol Biol (2010) 0.75
Cytotoxicity of methanol extracts of Annona muricata, Passiflora edulis and nine other Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines. Springerplus (2016) 0.75
Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line. Mediators Inflamm (2015) 0.75
Toxicogenomics of nanoparticulate delivery of etoposide: potential impact on nanotechnology in retinoblastoma therapy. Cancer Nanotechnol (2010) 0.75
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies. BMC Bioinformatics (2008) 2.54
Cameroonian medicinal plants: pharmacology and derived natural products. Front Pharmacol (2010) 1.80
Chemotherapy-induced resistance by ATP-binding cassette transporter genes. Biochim Biophys Acta (2007) 1.79
Molecular principles of cancer invasion and metastasis (review). Int J Oncol (2009) 1.66
Evidence-based Chinese medicine for cancer therapy. J Ethnopharmacol (2007) 1.47
Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts. J Ethnopharmacol (2011) 1.46
Toll-like 4 receptor variant, Asp299Gly, and reduced risk of hemorrhagic cystitis after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (2012) 1.42
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production. J Biol Chem (2010) 1.41
Antimicrobial activity of clove and rosemary essential oils alone and in combination. Phytother Res (2007) 1.39
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron. Free Radic Biol Med (2004) 1.37
Artesunate derived from traditional Chinese medicine induces DNA damage and repair. Cancer Res (2008) 1.31
Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate. Biochem Pharmacol (2004) 1.28
Modulation of human BCRP (ABCG2) activity by anti-HIV drugs. J Antimicrob Chemother (2007) 1.27
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway. J Cell Sci (2005) 1.26
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation. Clin Infect Dis (2008) 1.23
Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation. Methods (2002) 1.21
Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). Ann N Y Acad Sci (2007) 1.21
Antibacterial activity and anticancer activity of Rosmarinus officinalis L. essential oil compared to that of its main components. Molecules (2012) 1.20
A microarray-based detection system for genetically modified (GM) food ingredients. Plant Mol Biol (2006) 1.19
Artesunate in the treatment of metastatic uveal melanoma--first experiences. Oncol Rep (2005) 1.19
The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo. Antiviral Res (2005) 1.14
Leishmaniasis: drug resistance and natural products (review). Int J Mol Med (2008) 1.13
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts. Free Radic Biol Med (2002) 1.13
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants. PLoS One (2011) 1.12
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia. Clin Cancer Res (2006) 1.11
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system. Antiviral Res (2005) 1.10
Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells. Mol Cancer Ther (2011) 1.10
Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV). Planta Med (2006) 1.09
Polo-like kinase 1 as target for cancer therapy. Exp Hematol Oncol (2012) 1.09
Molecular biology of cantharidin in cancer cells. Chin Med (2007) 1.08
Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition. J Biol Chem (2012) 1.08
Proteome analysis and identification of symbiosis-related proteins from Medicago truncatula Gaertn. by two-dimensional electrophoresis and mass spectrometry. Electrophoresis (2002) 1.08
CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes. J Cell Sci (2006) 1.08
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases. Int J Cancer (2010) 1.07
Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities. J Ethnopharmacol (2010) 1.06
Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate. PLoS One (2007) 1.06
Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum. Biochem Pharmacol (2012) 1.05
Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense. J Ethnopharmacol (2013) 1.04
MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60. Cancer Genomics Proteomics (2010) 1.04
Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma. Anticancer Res (2011) 1.04
Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia. Mol Cancer Ther (2006) 1.03
Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells. Evid Based Complement Alternat Med (2012) 1.02
Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway. Chem Biol Interact (2010) 1.02
Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells. Nitric Oxide (2008) 1.02
UVB-induced premature senescence of human diploid skin fibroblasts. Int J Biochem Cell Biol (2002) 1.01
Stress-induced premature senescence and tissue ageing. Biochem Pharmacol (2002) 1.01
Therapeutic and diagnostic applications of nanoparticles. Curr Drug Targets (2011) 1.00
Drug resistance in Plasmodium: natural products in the fight against malaria. Mini Rev Med Chem (2009) 1.00
Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Treatment of human African trypanosomiasis with natural products (Review). Int J Mol Med (2008) 0.98
Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy. J Ethnopharmacol (2011) 0.98
Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients. Clin Cancer Res (2002) 0.97
First study of oral Artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markers. Anticancer Res (2011) 0.97
Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray. Biochem Pharmacol (2002) 0.96
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts. FEBS Lett (2002) 0.96
Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes. Toxicol Sci (2003) 0.96
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide. Cell Stress Chaperones (2002) 0.96
Hypomethylation of PRAME is responsible for its aberrant overexpression in human malignancies. Genes Chromosomes Cancer (2007) 0.95
Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions? ScientificWorldJournal (2002) 0.95
Clinical implications of c-Kit mutations in acute myelogenous leukemia. Curr Hematol Malig Rep (2009) 0.95
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo. BMC Cancer (2006) 0.95
Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from Geranium sibiricum L. J Agric Food Chem (2010) 0.95
Cytotoxicity and Modes of Action of the Methanol Extracts of Six Cameroonian Medicinal Plants against Multidrug-Resistant Tumor Cells. Evid Based Complement Alternat Med (2013) 0.95
P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs. J Ethnopharmacol (2011) 0.95
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin. Radiother Oncol (2012) 0.94
Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol. Planta Med (2011) 0.93
Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity. Bioresour Technol (2009) 0.93
Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia. Br J Haematol (2002) 0.93
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol. Phytomedicine (2013) 0.93
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. Int J Oncol (2003) 0.93
Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells. Biochem Pharmacol (2009) 0.92
New chips for molecular biology and diagnostics. Biotechnol Annu Rev (2002) 0.92
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts. FEBS Lett (2006) 0.92
Optimization of luteolin separation from pigeonpea [Cajanus cajan (L.) Millsp.] leaves by macroporous resins. J Chromatogr A (2006) 0.92
Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation. Antiviral Res (2011) 0.91
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines. Genes Chromosomes Cancer (2005) 0.91
Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa. Planta Med (2007) 0.91
Molecular mechanisms underlying St. John's wort drug interactions. Curr Drug Metab (2008) 0.91
Review. Drug resistance of human immunodeficiency virus and overcoming it by natural products. In Vivo (2009) 0.91
Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells. Molecules (2010) 0.91
Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms. J Ethnopharmacol (2012) 0.91
Fighting cancer with red wine? Molecular mechanisms of resveratrol. Crit Rev Food Sci Nutr (2009) 0.90
Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children. Biol Blood Marrow Transplant (2009) 0.90
Herpes simplex virus: Drug resistance and new treatment options using natural products (Review). Mol Med Rep (2011) 0.89
Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue. Lung Cancer (2012) 0.89
Fuzzy-logic based strategy for validation of multiplex methods: example with qualitative GMO assays. Transgenic Res (2009) 0.89
Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy? Evid Based Complement Alternat Med (2013) 0.88