Published in Genomics on January 01, 2005
Influence of genetic background on genetically engineered mouse phenotypes. Methods Mol Biol (2009) 1.70
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia. Nat Commun (2012) 1.13
Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility. Proc Natl Acad Sci U S A (2006) 0.97
Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus. Proc Natl Acad Sci U S A (2012) 0.84
Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans. Proc Natl Acad Sci U S A (2014) 0.83
Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tract. Int J Biol Sci (2010) 0.83
Mice with disrupted TGFbeta signaling have normal cerebella development, but exhibit facial dysmorphogenesis and strain-dependent deficits in their body wall. Cell Mol Neurobiol (2009) 0.78
Mouse genetic background influences the dental phenotype. Cells Tissues Organs (2014) 0.78
Common polymorphisms in angiogenesis. Cold Spring Harb Perspect Med (2012) 0.78
Tgf-Beta superfamily receptors-targets for antiangiogenic therapy? J Oncol (2010) 0.77
Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model. PLoS One (2014) 0.75
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Nature (2012) 4.01
Identification of protein pheromones that promote aggressive behaviour. Nature (2007) 3.55
Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat Cell Biol (2002) 3.52
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47
The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs. Cell (2010) 2.88
Differentiation plasticity regulated by TGF-beta family proteins in development and disease. Nat Cell Biol (2007) 2.75
Evolutionary dynamics of Vibrio cholerae O1 following a single-source introduction to Haiti. MBio (2013) 2.24
Complexities of TGF-β targeted cancer therapy. Int J Biol Sci (2012) 1.84
TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion. J Cell Sci (2012) 1.74
Transforming growth factor-beta in breast cancer: too much, too late. Breast Cancer Res (2009) 1.51
TGF beta signaling in health and disease. Nat Genet (2004) 1.48
The type I TGF-beta receptor is covalently modified and regulated by sumoylation. Nat Cell Biol (2008) 1.37
Ten simple rules for editing Wikipedia. PLoS Comput Biol (2010) 1.36
The class I bHLH factors E2-2A and E2-2B regulate EMT. J Cell Sci (2009) 1.34
TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Clin Cancer Res (2011) 1.30
TGF beta inhibition for cancer therapy. Curr Cancer Drug Targets (2006) 1.24
Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res (2002) 1.23
Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing. Nucleic Acids Res (2012) 1.21
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia. Nat Commun (2012) 1.13
Phase transitions in biogenic amorphous calcium carbonate. Proc Natl Acad Sci U S A (2012) 1.10
The paradoxical TGF-β vasculopathies. Nat Genet (2012) 1.09
Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β. J Neurosci (2012) 1.08
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression. Am J Hum Genet (2009) 1.08
Global methylation state at base-pair resolution of the Caulobacter genome throughout the cell cycle. Proc Natl Acad Sci U S A (2013) 1.06
Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochem Biophys Res Commun (2006) 1.06
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. PLoS Genet (2012) 1.06
The mouse genetics toolkit: revealing function and mechanism. Genome Biol (2011) 1.05
Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice. Hum Mol Genet (2003) 1.03
Mutations of TGFbeta signaling molecules in human disease. Ann Med (2006) 1.03
Olfactory mechanisms of stereotyped behavior: on the scent of specialized circuits. Curr Opin Neurobiol (2010) 1.03
Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761. Cancer Res (2011) 1.01
Sexual dimorphism in olfactory signaling. Curr Opin Neurobiol (2010) 1.01
Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility. Proc Natl Acad Sci U S A (2006) 0.97
ISCB computational biology Wikipedia competition. PLoS Comput Biol (2013) 0.96
Mouse strain-dependent heterogeneity of resting limbal vasculature. Invest Ophthalmol Vis Sci (2004) 0.93
ATM mutations are rare in familial chronic lymphocytic leukemia. Blood (2002) 0.91
Time to underpin Wikipedia wisdom. Nature (2010) 0.90
The genomic basis of vomeronasal-mediated behaviour. Mamm Genome (2013) 0.90
Relationship between glutathione S-transferase M1, T1, and P1 polymorphisms and chronic lymphocytic leukemia. Blood (2002) 0.89
The Giardia cell cycle progresses independently of the anaphase-promoting complex. J Cell Sci (2013) 0.89
TGFbeta inhibition of yolk-sac-like differentiation of human embryonic stem-cell-derived embryoid bodies illustrates differences between early mouse and human development. J Cell Sci (2006) 0.88
Multiple Genome Sequences of Helicobacter pylori Strains of Diverse Disease and Antibiotic Resistance Backgrounds from Malaysia. Genome Announc (2013) 0.87
Genomic variation in the vomeronasal receptor gene repertoires of inbred mice. BMC Genomics (2012) 0.87
Large-scale analysis of gene structure in rhodopsin-like GPCRs: evidence for widespread loss of an ancient intron. Gene (2004) 0.86
LUSH shapes up for a starring role in olfaction. Cell (2008) 0.84
Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus. Proc Natl Acad Sci U S A (2012) 0.84
Cell-cycle regulation of formin-mediated actin cable assembly. Proc Natl Acad Sci U S A (2013) 0.83
Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients. Clin Cancer Res (2009) 0.81
The complexities of TGF-β action during mammary and squamous cell carcinogenesis. Curr Pharm Biotechnol (2011) 0.81
Somatic mosaicism for the p.His1047Arg mutation in PIK3CA in a girl with mesenteric lipomatosis. Am J Med Genet A (2014) 0.80
Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition. PLoS One (2012) 0.80
Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles. Genome Res (2015) 0.79
Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology. J Invest Dermatol (2013) 0.79
Generation of the Sotos syndrome deletion in mice. Mamm Genome (2012) 0.79
Olfaction and olfactory-mediated behaviour in psychiatric disease models. Cell Tissue Res (2013) 0.79
A sweet link between TGFbeta and vascular disease? Nat Genet (2006) 0.79
Taking thalidomide out of rehab. Nat Med (2010) 0.78
Instability of CAG-trinucleotide repeats in chronic lymphocytic leukemia. Leuk Lymphoma (2002) 0.77
Breakpoints in the ataxia telangiectasia gene arise at the RGYW somatic hypermutation motif. Oncogene (2002) 0.76
BMP-9 balances endothelial cell fate. Proc Natl Acad Sci U S A (2013) 0.75
An animal model to evaluate the function and regulation of the adaptively evolving stress protein SEP53 in oesophageal bile damage responses. Cell Stress Chaperones (2008) 0.75
27th International Mammalian Genome Conference meeting report. Mamm Genome (2014) 0.75
Cancer: dangerous liaisons. Nature (2004) 0.75