Published in J Biol Chem on December 21, 2004
The gap junction cellular internet: connexin hemichannels enter the signalling limelight. Biochem J (2006) 2.24
Intracellular calcium changes trigger connexin 32 hemichannel opening. EMBO J (2005) 1.69
Gap junctions. Compr Physiol (2012) 1.59
Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia. Sci Signal (2012) 1.42
Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels. Proc Natl Acad Sci U S A (2012) 1.38
Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress. Front Biosci (2007) 1.34
Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor. Mol Biol Cell (2006) 1.30
Paracrine signaling through plasma membrane hemichannels. Biochim Biophys Acta (2012) 1.28
Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovasc Res (2012) 1.27
Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating. J Gen Physiol (2008) 1.26
How do seizures stop? Epilepsia (2008) 1.25
Adhesive properties of connexin hemichannels. Glia (2008) 1.14
A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury. PLoS One (2007) 1.12
Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm. Biochim Biophys Acta (2007) 1.11
Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y). J Gen Physiol (2013) 1.06
Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization. Am J Physiol Cell Physiol (2010) 1.05
K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis. J Am Chem Soc (2009) 0.97
Structural basis for the selective permeability of channels made of communicating junction proteins. Biochim Biophys Acta (2012) 0.97
Manipulating connexin communication channels: use of peptidomimetics and the translational outputs. J Membr Biol (2012) 0.95
Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces. J Biol Chem (2011) 0.94
Specific and selective peptide-membrane interactions revealed using quartz crystal microbalance. Biophys J (2007) 0.93
Cx23, a connexin with only four extracellular-loop cysteines, forms functional gap junction channels and hemichannels. FEBS Lett (2007) 0.92
Voltage-dependent gating of the Cx32*43E1 hemichannel: conformational changes at the channel entrances. J Gen Physiol (2013) 0.91
Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway. J Biol Chem (2012) 0.88
Functional evaluation of GJB2 variants in nonsyndromic hearing loss. Mol Med (2011) 0.85
The role of connexin 43 and hemichannels correlated with the astrocytic death following ischemia/reperfusion insult. Cell Mol Neurobiol (2013) 0.83
Differential modulation of unapposed connexin 43 hemichannel electrical conductance by protein kinase C isoforms. Pflugers Arch (2008) 0.83
Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost (2014) 0.83
Conformational maturation and post-ER multisubunit assembly of gap junction proteins. Mol Biol Cell (2009) 0.83
Synaptic impairment induced by paroxysmal ionic conditions in neocortex. Epilepsia (2010) 0.83
Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis. Am J Physiol Cell Physiol (2013) 0.83
Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing. Front Physiol (2014) 0.83
Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death. PLoS One (2012) 0.81
Multidimensional atomic force microscopy: a versatile novel technology for nanopharmacology research. AAPS J (2010) 0.80
Anti-arrhythmic effect of acupuncture pretreatment in the rats subjected to simulative global ischemia and reperfusion--involvement of intracellular Ca2+ and connexin 43. BMC Complement Altern Med (2015) 0.80
Dynamics of high-frequency synchronization during seizures. J Neurophysiol (2013) 0.79
Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation. J Mol Cell Cardiol (2015) 0.77
Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. Sci Rep (2014) 0.77
Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Tauopathies. Biochemistry (2015) 0.77
In vivo models of cortical acquired epilepsy. J Neurosci Methods (2015) 0.77
Specialized Functional Diversity and Interactions of the Na,K-ATPase. Front Physiol (2016) 0.76
Not what you thought: how H+ ions combine with taurine or other aminosulfonates to close Cx26 channels. J Gen Physiol (2011) 0.76
A history of gap junction structure: hexagonal arrays to atomic resolution. Cell Commun Adhes (2013) 0.76
Extracellular Ca2+ fluctuations in vivo affect afterhyperpolarization potential and modify firing patterns of neocortical neurons. Exp Neurol (2012) 0.75
Connexin 43 and Its Hemichannels Mediate Hypoxia-Ischemia-Induced Cell Death in Neonatal Rats. Child Neurol Open (2014) 0.75
Anti-arrhythmic effect of verapamil is accompanied by preservation of cx43 protein in rat heart. PLoS One (2013) 0.75
Atomic force microscopy shows connexin26 hemichannel clustering in purified membrane fragments. Biochemistry (2014) 0.75
Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H2O2 Production. J Biol Chem (2016) 0.75
Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications. Pharmacol Rev (2017) 0.75
Regulation of Cx45 hemichannels mediated by extracellular and intracellular calcium. Pflugers Arch (2012) 0.75
The pathological effects of connexin 26 variants related to hearing loss by in silico and in vitro analysis. Hum Genet (2016) 0.75
Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol (2015) 5.10
Amyloid ion channels: a common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A (2005) 3.91
Disparities in diabetes care: impact of mental illness. Arch Intern Med (2005) 2.45
Influence of topology on bacterial social interaction. Proc Natl Acad Sci U S A (2003) 2.07
Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma. Proteomics (2013) 1.93
Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome. Proc Natl Acad Sci U S A (2010) 1.48
New structures help the modeling of toxic amyloidbeta ion channels. Trends Biochem Sci (2008) 1.43
Engineering the cell-material interface for controlling stem cell adhesion, migration, and differentiation. Biomaterials (2011) 1.41
Mortality among patients with acute myocardial infarction: the influences of patient-centered care and evidence-based medicine. Health Serv Res (2010) 1.41
Does Helicobacter pylori infection play a role in iron deficiency anemia? A meta-analysis. World J Gastroenterol (2010) 1.34
Biomechanical properties of native basement membranes. FEBS J (2007) 1.31
Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels. Biophys J (2008) 1.30
MIAME/Plant - adding value to plant microarrray experiments. Plant Methods (2006) 1.29
Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function. Mol Biol Cell (2010) 1.23
Quantum mechanical/molecular mechanical investigation of the mechanism of C-H hydroxylation of camphor by cytochrome P450cam: theory supports a two-state rebound mechanism. J Am Chem Soc (2004) 1.22
β-Barrel topology of Alzheimer's β-amyloid ion channels. J Mol Biol (2010) 1.21
Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: atomic force microscopy force mapping of pulmonary endothelial monolayer. Nanomedicine (2008) 1.21
Racial/ethnic differences in diabetes care for older veterans: accounting for dual health system use changes conclusions. Med Care (2006) 1.20
The elusive oxidant species of cytochrome P450 enzymes: characterization by combined quantum mechanical/molecular mechanical (QM/MM) calculations. J Am Chem Soc (2002) 1.19
Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol (2008) 1.19
Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels. Biophys J (2009) 1.18
Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link. Biophys J (2011) 1.17
Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release. Nano Lett (2010) 1.17
Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity. Langmuir (2006) 1.16
Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. Biophys J (2008) 1.16
The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. J Exp Med (2009) 1.12
A decade of Bt cotton in Chinese fields: assessing the direct effects and indirect externalities of Bt cotton adoption in China. Sci China Life Sci (2010) 1.12
Study on acetate ion recognition and sensing in aqueous media using a novel and simple colorimetric sensor and its analytical application. Talanta (2007) 1.12
A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury. PLoS One (2007) 1.12
Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm. Biochim Biophys Acta (2007) 1.11
Iron deficiency anaemia can be improved after eradication of Helicobacter pylori. Postgrad Med J (2010) 1.11
Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells. Tissue Eng (2007) 1.11
Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology. J Phys Chem B (2012) 1.11
The combined effects of prenatal drug exposure and early adversity on neurobehavioral disinhibition in childhood and adolescence. Dev Psychopathol (2011) 1.09
Evaporative self-assembly assisted synthesis of polymeric nanoparticles by surface acoustic wave atomization. Nanotechnology (2008) 1.09
Structural convergence among diverse, toxic beta-sheet ion channels. J Phys Chem B (2010) 1.08
alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern. J Nutr (2006) 1.07
A new method for stranded whole transcriptome RNA-seq. Methods (2013) 1.05
Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics (2012) 1.03
DDIG-in: discriminating between disease-associated and neutral non-frameshifting micro-indels. Genome Biol (2013) 1.02
Antimicrobial properties of amyloid peptides. Mol Pharm (2011) 1.02
Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing. J Biol Chem (2006) 1.02
Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): a novel antibacterial peptide optimized against gram-negative human pathogens. J Med Chem (2010) 1.01
Motor and cognitive outcomes through three years of age in children exposed to prenatal methamphetamine. Neurotoxicol Teratol (2011) 1.00
Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions. Biochemistry (2012) 1.00
Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane. J Chem Theory Comput (2012) 0.99
COPI transport complexes bind to specific RNAs in neuronal cells. Hum Mol Genet (2012) 0.99
The effects of prenatal methamphetamine exposure on childhood growth patterns from birth to 3 years of age. Am J Perinatol (2011) 0.98
Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies. Biophys J (2010) 0.98
DEK overexpression in uterine cervical cancers. Pathol Int (2008) 0.98
AFM nanoindentations of diatom biosilica surfaces. Langmuir (2007) 0.98
K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis. J Am Chem Soc (2009) 0.97
Neurobehavioral disinhibition predicts initiation of substance use in children with prenatal cocaine exposure. Drug Alcohol Depend (2012) 0.96
Imaging real-time aggregation of amyloid beta protein (1-42) by atomic force microscopy. Peptides (2002) 0.96
Organization of cytochrome P450 enzymes involved in sex steroid synthesis: PROTEIN-PROTEIN INTERACTIONS IN LIPID MEMBRANES. J Biol Chem (2009) 0.95
All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers. J Chem Theory Comput (2012) 0.95
Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations. Biochemistry (2012) 0.95
Magnetic targeting of nanoparticles across the intact blood-brain barrier. J Control Release (2012) 0.95
Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces. J Biol Chem (2011) 0.94
High resolution scanning tunnelling microscopy of the beta-amyloid protein (Abeta1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly. J Struct Biol (2006) 0.94
Alzheimer's disease: which type of amyloid-preventing drug agents to employ? Phys Chem Chem Phys (2013) 0.91
Infant temperament and high-risk environment relate to behavior problems and language in toddlers. J Dev Behav Pediatr (2011) 0.91
CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells. J Hematol Oncol (2014) 0.90
Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: lab-on-a-chip system for lipid membranes and ion channels. Langmuir (2007) 0.90
Synthesis, characterization and biological activity of lanthanum(III) complexes containing 2-methylene-1,10-phenanthroline units bridged by aliphatic diamines. J Inorg Biochem (2005) 0.90
Neonatal neurobehavior effects following buprenorphine versus methadone exposure. Addiction (2012) 0.88
Pancreaticojejunostomy versus pancreaticogastrostomy after pancreaticoduodenectomy: a systematic review and meta-analysis. Dig Surg (2013) 0.88
High performance, LED powered, waveguide based total internal reflection microscopy. Sci Rep (2013) 0.87
Adaptive partitioning in combined quantum mechanical and molecular mechanical calculations of potential energy functions for multiscale simulations. J Phys Chem B (2007) 0.87
Prenatal methamphetamine exposure and inhibitory control among young school-age children. J Pediatr (2012) 0.87
Distribution of HPV genotypes in uterine cervical lesions in Yanbian, northern China. Pathol Int (2008) 0.86
Voltage-gated divalent currents in descending vasa recta pericytes. Am J Physiol Renal Physiol (2010) 0.86
Nanoscale structural and mechanical properties of nontypeable Haemophilus influenzae biofilms. J Bacteriol (2009) 0.86
Increased de novo lipogenesis in liver contributes to the augmented fat deposition in dexamethasone exposed broiler chickens (Gallus gallus domesticus). Comp Biochem Physiol C Toxicol Pharmacol (2009) 0.86
Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs. Chem Soc Rev (2014) 0.86
Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation. Soft Matter (2011) 0.86
Regulation of microRNA expression by rifampin in human hepatocytes. Drug Metab Dispos (2013) 0.85
Transthyretin oligomers induce calcium influx via voltage-gated calcium channels. J Neurochem (2006) 0.85
Graphene nanopore support system for simultaneous high-resolution AFM imaging and conductance measurements. ACS Appl Mater Interfaces (2014) 0.85
Tm3+-doped tellurite glasses for fiber amplifiers in broadband optical communication at 1.20 µm wavelength region. Opt Express (2010) 0.84
DNA zipper-based tweezers. Langmuir (2011) 0.84
[Study on processing technology and processing principles of atractrylodis macrocephalae rhizoma]. Zhongguo Zhong Yao Za Zhi (2011) 0.84
Ammonia-nitrogen and phosphates sorption from simulated reclaimed waters by modified clinoptilolite. J Hazard Mater (2012) 0.84
Effect of corticosterone on gene expression of feed intake regulatory peptides in laying hens. Comp Biochem Physiol B Biochem Mol Biol (2012) 0.83
Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment. J Phys Chem B (2013) 0.83
Subunit composition and role of Na+,K+-ATPases in ventricular myocytes. J Physiol Sci (2006) 0.83
Fasting alters protein expression of AMP-activated protein kinase in the hypothalamus of broiler chicks (Gallus gallus domesticus). Gen Comp Endocrinol (2012) 0.83
Correlation of atomic force microscopy and Raman micro-spectroscopy to study the effects of ex vivo treatment procedures on human red blood cells. Analyst (2010) 0.83
Glucocorticoids increase NPY gene expression via hypothalamic AMPK signaling in broiler chicks. Endocrinology (2014) 0.83
Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways. Physiol Genomics (2013) 0.82
Structure-Aware Lighting Design for Volume Visualization. IEEE Trans Vis Comput Graph (2012) 0.82
Heterogeneous elastic response of human lung microvascular endothelial cells to barrier modulating stimuli. Nanomedicine (2013) 0.82
Colorimetric recognizing of biologically important anions based on anion-induced tautomerism of the sensor. J Mol Recognit (2008) 0.82
An on-demand four-way junction DNAzyme nanoswitch driven by inosine-based partial strand displacement. Nanoscale (2014) 0.81
Effects of cyclic AMP on the function of the cardiac gap junction during hypoxia. Exp Clin Cardiol (2006) 0.81
Multicoefficient Gaussian-3 calculation of the rate constant for the OH + CH4 reaction and its 12C/13C kinetic isotope effect with emphasis on the effects of coordinate system and torsional treatment. J Phys Chem A (2007) 0.81
Impact of human pathogenic micro-insertions and micro-deletions on post-transcriptional regulation. Hum Mol Genet (2014) 0.81
[Determination of effective components in different positions of Panax notoginseng by HPLC]. Zhong Yao Cai (2009) 0.81
The role of diatom nanostructures in biasing diffusion to improve uptake in a patchy nutrient environment. PLoS One (2013) 0.81