Published in Hum Mol Genet on November 21, 2012
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat Chem (2013) 1.48
Spinal muscular atrophy: development and implementation of potential treatments. Ann Neurol (2013) 1.01
Dilysine motifs in exon 2b of SMN protein mediate binding to the COPI vesicle protein α-COP and neurite outgrowth in a cell culture model of spinal muscular atrophy. Hum Mol Genet (2013) 0.88
Regulation of microRNA expression by rifampin in human hepatocytes. Drug Metab Dispos (2013) 0.85
Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways. Physiol Genomics (2013) 0.82
Lipopolysaccharide treatment induces genome-wide pre-mRNA splicing pattern changes in mouse bone marrow stromal stem cells. BMC Genomics (2016) 0.80
Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking. Pharmacol Biochem Behav (2014) 0.78
Golgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport Vesicles. Front Neurosci (2015) 0.78
α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth. Hum Mol Genet (2015) 0.77
Age-Related Changes in MicroRNA Expression and Pharmacogenes in Human Liver. Clin Pharmacol Ther (2015) 0.77
Gemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN Expression. J Biol Chem (2015) 0.77
ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects. Am J Hum Genet (2016) 0.76
Depletion of ε-COP in the COPI Vesicular Coat Reduces Cleistothecium Production in Aspergillus nidulans. Mycobiology (2015) 0.75
SCYL pseudokinases in neuronal function and survival. Neural Regen Res (2016) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
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MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res (2009) 23.27
Moderated statistical tests for assessing differences in tag abundance. Bioinformatics (2007) 22.87
Small-sample estimation of negative binomial dispersion, with applications to SAGE data. Biostatistics (2007) 18.19
Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature (2008) 12.21
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
BFAST: an alignment tool for large scale genome resequencing. PLoS One (2009) 7.48
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell (2001) 6.50
Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res (2005) 5.34
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J Neurochem (2006) 3.67
Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell (2012) 3.50
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev Dyn (1992) 3.14
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Subcellular mRNA localization in animal cells and why it matters. Science (2009) 2.54
Immunoprecipitation of mRNA-protein complexes. Nat Protoc (2006) 2.21
Mechanisms of subcellular mRNA localization. Cell (2002) 2.21
bicoid RNA localization requires specific binding of an endosomal sorting complex. Nature (2007) 2.11
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. RNA (2010) 2.07
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet (2002) 2.05
The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions. Science (2012) 1.90
Synthesis of beta-tubulin, actin, and other proteins in axons of sympathetic neurons in compartmented cultures. J Neurosci (1999) 1.89
The COPI system: molecular mechanisms and function. FEBS Lett (2009) 1.88
Local RNA translation at the synapse and in disease. J Neurosci (2011) 1.83
The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences. Neuroscience (2003) 1.69
Mechanisms of dendritic mRNA transport and its role in synaptic tagging. EMBO J (2011) 1.58
G-quadruplexes in RNA biology. Wiley Interdiscip Rev RNA (2012) 1.55
Coordination of endoplasmic reticulum and mRNA localization to the yeast bud. Curr Biol (2006) 1.45
A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci (2008) 1.40
Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains. Nat Struct Mol Biol (2009) 1.31
Endoplasmic reticulum export site formation and function in dendrites. J Neurosci (2004) 1.28
Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev (2012) 1.26
Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat. J Cell Biol (2011) 1.25
The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro. Cell Motil Cytoskeleton (1998) 1.24
HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects. Hum Mol Genet (2010) 1.21
GAP-43 mRNA in growth cones is associated with HuD and ribosomes. J Neurobiol (2004) 1.21
Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic. J Biol Chem (2008) 1.17
Single-molecule assays reveal that RNA localization signals regulate dynein-dynactin copy number on individual transcript cargoes. Nat Cell Biol (2012) 1.17
Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers. EMBO Rep (2011) 1.17
Inhibition of axonal growth by brefeldin A in hippocampal neurons in culture. J Neurosci (1997) 1.14
RNA localisation in the nervous system. Semin Cell Dev Biol (2007) 1.09
In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein. J Biol Chem (2007) 1.08
The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet (2011) 1.08
The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Front Neural Circuits (2010) 1.05
Copb1-facilitated axonal transport and translation of kappa opioid-receptor mRNA. Proc Natl Acad Sci U S A (2007) 1.03
Arf1p provides an unexpected link between COPI vesicles and mRNA in Saccharomyces cerevisiae. Mol Biol Cell (2004) 0.94
Messenger RNA on the move: implications for cell polarity. Int J Biochem Cell Biol (2001) 0.93
Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration. PLoS Genet (2010) 0.92
Human pathologies associated with defective RNA transport and localization in the nervous system. Biol Cell (2007) 0.83
The cytoplasmic coatomer protein COPI. A potential translational regulator. J Biol Chem (1999) 0.78
RNA localization: new roles for an evolutionarily ancient mechanism. Semin Cell Dev Biol (2007) 0.78
miR2Disease: a manually curated database for microRNA deregulation in human disease. Nucleic Acids Res (2008) 6.30
Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol (2015) 5.10
Amyloid ion channels: a common structural link for protein-misfolding disease. Proc Natl Acad Sci U S A (2005) 3.91
Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Res (2008) 3.33
Disparities in diabetes care: impact of mental illness. Arch Intern Med (2005) 2.45
Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron. Mol Cell Biol (2006) 2.41
Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Res (2009) 2.27
Predicting intrinsic disorder in proteins: an overview. Cell Res (2009) 2.24
Influence of topology on bacterial social interaction. Proc Natl Acad Sci U S A (2003) 2.07
MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst (2010) 1.94
Alcohol alters DNA methylation patterns and inhibits neural stem cell differentiation. Alcohol Clin Exp Res (2011) 1.88
Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes. Nucleic Acids Res (2006) 1.84
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy. J Cell Biol (2003) 1.75
Optimal graph search segmentation using arc-weighted graph for simultaneous surface detection of bladder and prostate. Med Image Comput Comput Assist Interv (2009) 1.69
In vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes. RNA (2004) 1.60
An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy. Biochem Biophys Res Commun (2004) 1.56
SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet (2002) 1.53
A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology. BMC Genomics (2008) 1.49
Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chem Biol (2004) 1.45
Calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannels. J Biol Chem (2004) 1.44
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. J Cell Sci (2006) 1.42
Mortality among patients with acute myocardial infarction: the influences of patient-centered care and evidence-based medicine. Health Serv Res (2010) 1.41
Knee loading dynamically alters intramedullary pressure in mouse femora. Bone (2006) 1.40
Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. PLoS One (2012) 1.40
ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance. Mol Cell (2006) 1.39
Prioritization of disease microRNAs through a human phenome-microRNAome network. BMC Syst Biol (2010) 1.37
Knee-loading modality drives molecular transport in mouse femur. Ann Biomed Eng (2006) 1.36
Does Helicobacter pylori infection play a role in iron deficiency anemia? A meta-analysis. World J Gastroenterol (2010) 1.34
Gene expression patterns in bone following mechanical loading. J Bone Miner Res (2011) 1.32
Biomechanical properties of native basement membranes. FEBS J (2007) 1.31
Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene. J Biol Chem (2011) 1.31
NGSUtils: a software suite for analyzing and manipulating next-generation sequencing datasets. Bioinformatics (2013) 1.28
Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance. Bioinformatics (2008) 1.27
The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle (2012) 1.24
Quantum mechanical/molecular mechanical investigation of the mechanism of C-H hydroxylation of camphor by cytochrome P450cam: theory supports a two-state rebound mechanism. J Am Chem Soc (2004) 1.22
AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer. Mol Cell Biol (2008) 1.21
Racial/ethnic differences in diabetes care for older veterans: accounting for dual health system use changes conclusions. Med Care (2006) 1.20
A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem (2001) 1.20
Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Med Genomics (2013) 1.19
The elusive oxidant species of cytochrome P450 enzymes: characterization by combined quantum mechanical/molecular mechanical (QM/MM) calculations. J Am Chem Soc (2002) 1.19
GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplant (2008) 1.19
Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model. Hum Mol Genet (2009) 1.19
Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol (2008) 1.19
Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes. J Virol (2002) 1.19
A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum Mol Genet (2010) 1.15
Chromosome 7 and 19 trisomy in cultured human neural progenitor cells. PLoS One (2009) 1.13
A decade of Bt cotton in Chinese fields: assessing the direct effects and indirect externalities of Bt cotton adoption in China. Sci China Life Sci (2010) 1.12
Study on acetate ion recognition and sensing in aqueous media using a novel and simple colorimetric sensor and its analytical application. Talanta (2007) 1.12
Transcription factor and microRNA regulation in androgen-dependent and -independent prostate cancer cells. BMC Genomics (2008) 1.12
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am J Hum Genet (2013) 1.11
Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm. Biochim Biophys Acta (2007) 1.11
Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells. Tissue Eng (2007) 1.11
Iron deficiency anaemia can be improved after eradication of Helicobacter pylori. Postgrad Med J (2010) 1.11
Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy. J Neurosci Methods (2007) 1.11
Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras. J Virol (2004) 1.10
Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer. Cancer Cell (2013) 1.09
The combined effects of prenatal drug exposure and early adversity on neurobehavioral disinhibition in childhood and adolescence. Dev Psychopathol (2011) 1.09
The regulation and regulatory activities of alternative splicing of the SMN gene. Crit Rev Eukaryot Gene Expr (2004) 1.08
Alteration of gene expression by alcohol exposure at early neurulation. BMC Genomics (2011) 1.08
The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet (2011) 1.08
alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern. J Nutr (2006) 1.07
RNA polymerase II binding patterns reveal genomic regions involved in microRNA gene regulation. PLoS One (2010) 1.07
Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells. Gastroenterology (2012) 1.07
Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture. Stem Cells Transl Med (2014) 1.07
Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients. Breast Cancer Res (2011) 1.05
A new method for stranded whole transcriptome RNA-seq. Methods (2013) 1.05
Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF. Cell Transplant (2008) 1.05
Identification of genes and pathways involved in kidney renal clear cell carcinoma. BMC Bioinformatics (2014) 1.05
Laboratory methods for high-throughput genotyping. Cold Spring Harb Protoc (2009) 1.04
A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers. Oncotarget (2010) 1.03
Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics (2012) 1.03
Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins. Antiviral Res (2006) 1.02
DDIG-in: discriminating between disease-associated and neutral non-frameshifting micro-indels. Genome Biol (2013) 1.02
Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. BMC Genomics (2008) 1.02
Motor and cognitive outcomes through three years of age in children exposed to prenatal methamphetamine. Neurotoxicol Teratol (2011) 1.00
Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Mol Cell Biol (2010) 1.00
A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer. BMC Syst Biol (2011) 0.99
TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells. Epigenetics (2014) 0.99
DEK overexpression in uterine cervical cancers. Pathol Int (2008) 0.98
The effects of prenatal methamphetamine exposure on childhood growth patterns from birth to 3 years of age. Am J Perinatol (2011) 0.98
Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability. J Virol (2008) 0.97
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol (2013) 0.97
Activation of CpxRA in Haemophilus ducreyi primarily inhibits the expression of its targets, including major virulence determinants. J Bacteriol (2013) 0.97
Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data. BMC Genomics (2012) 0.96
Neurobehavioral disinhibition predicts initiation of substance use in children with prenatal cocaine exposure. Drug Alcohol Depend (2012) 0.96
Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT. J Virol (2007) 0.96
Imaging real-time aggregation of amyloid beta protein (1-42) by atomic force microscopy. Peptides (2002) 0.96
Graph search with appearance and shape information for 3-D prostate and bladder segmentation. Med Image Comput Comput Assist Interv (2010) 0.95
Genome-wide prediction of cis-acting RNA elements regulating tissue-specific pre-mRNA alternative splicing. BMC Genomics (2009) 0.95
Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation. J Virol (2006) 0.93
Simultaneous inferences based on empirical Bayes methods and false discovery rates ineQTL data analysis. BMC Genomics (2013) 0.93
The Ewing's sarcoma protein interacts with the Tudor domain of the survival motor neuron protein. Brain Res Mol Brain Res (2003) 0.92
Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank. Breast Cancer Res (2014) 0.92
PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy. Cell Cycle (2012) 0.91
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. J Med Chem (2011) 0.91
Infant temperament and high-risk environment relate to behavior problems and language in toddlers. J Dev Behav Pediatr (2011) 0.91
CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells. J Hematol Oncol (2014) 0.90