Published in J Cell Sci on January 01, 2005
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
Chemotaxis in cancer. Nat Rev Cancer (2011) 3.68
The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci (2008) 3.04
Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. Cell (2007) 2.59
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol (2006) 2.59
Apical trafficking in epithelial cells: signals, clusters and motors. J Cell Sci (2009) 2.08
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol (2005) 2.05
The cofilin activity cycle in lamellipodia and invadopodia. J Cell Biochem (2009) 1.99
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J Cell Biol (2007) 1.93
Dicing with dogma: de-branching the lamellipodium. Trends Cell Biol (2010) 1.63
Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen. J Exp Med (2008) 1.63
Aip1 and cofilin promote rapid turnover of yeast actin patches and cables: a coordinated mechanism for severing and capping filaments. Mol Biol Cell (2006) 1.62
Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adh Migr (2011) 1.60
Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane. Neuron (2012) 1.58
A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J Cell Sci (2009) 1.45
Anesthetics impact the resolution of inflammation. PLoS One (2008) 1.42
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol (2011) 1.38
Regulation of membrane trafficking, cytoskeleton dynamics, and cell polarity by ROP/RAC GTPases. Plant Physiol (2008) 1.37
Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo. J Cell Sci (2010) 1.35
Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin. J Biol Chem (2010) 1.32
Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes. Cell Motil Cytoskeleton (2008) 1.31
Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. Cancer Cell (2012) 1.26
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
MicroRNA-205 promotes keratinocyte migration via the lipid phosphatase SHIP2. FASEB J (2010) 1.22
ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin. Dev Cell (2012) 1.20
The cytoskeleton coordinates the early events of B-cell activation. Cold Spring Harb Perspect Biol (2011) 1.17
The two Caenorhabditis elegans actin-depolymerizing factor/cofilin proteins differently enhance actin filament severing and depolymerization. Biochemistry (2005) 1.16
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin. EMBO J (2007) 1.14
Quantitative analysis of G-actin transport in motile cells. Biophys J (2008) 1.12
Growing actin networks form lamellipodium and lamellum by self-assembly. Biophys J (2008) 1.10
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A. Oncogene (2010) 1.10
Enhancement of actin-depolymerizing factor/cofilin-dependent actin disassembly by actin-interacting protein 1 is required for organized actin filament assembly in the Caenorhabditis elegans body wall muscle. Mol Biol Cell (2006) 1.05
An open model of actin dendritic nucleation. Biophys J (2009) 1.05
The actin cytoskeleton as a sensor and mediator of apoptosis. Bioarchitecture (2012) 1.03
Regulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupe. Traffic (2006) 1.01
MicroRNAs in skin and wound healing. Physiol Genomics (2010) 1.00
Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines. Open Neurosci J (2009) 0.99
Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data. Proc Natl Acad Sci U S A (2007) 0.98
Mammalian adenylyl cyclase-associated protein 1 (CAP1) regulates cofilin function, the actin cytoskeleton, and cell adhesion. J Biol Chem (2013) 0.96
Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer. Pharmacol Rev (2014) 0.96
Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering. Mol Biol Cell (2009) 0.94
Porphyromonas gingivalis SerB-mediated dephosphorylation of host cell cofilin modulates invasion efficiency. Cell Microbiol (2012) 0.93
ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol (2015) 0.93
Enrichment of distinct microfilament-associated and GTP-binding-proteins in membrane/microvilli fractions from lymphoid cells. J Proteome Res (2008) 0.93
Modeling of protein binary complexes using structural mass spectrometry data. Protein Sci (2007) 0.93
Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget (2015) 0.92
Immune pathology associated with altered actin cytoskeleton regulation. Autoimmunity (2010) 0.92
Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway. Cell Commun Signal (2013) 0.92
Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities. J Biol Chem (2009) 0.90
Application for proteomic techniques in studying osteoarthritis: a review. Front Physiol (2011) 0.90
Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics. PLoS One (2012) 0.90
Spatial regulation of RhoC activity defines protrusion formation in migrating cells. J Cell Sci (2013) 0.90
The increase in mitochondrial association with actin precedes Bax translocation in apoptosis. Biochem J (2006) 0.90
Cytoskeleton targeting value in prostate cancer treatment. Am J Clin Exp Urol (2014) 0.90
Actin dynamics regulated by the balance of neuronal Wiskott-Aldrich syndrome protein (N-WASP) and cofilin activities determines the biphasic response of glucose-induced insulin secretion. J Biol Chem (2013) 0.89
Mesenchymal migration as a therapeutic target in glioblastoma. J Oncol (2010) 0.89
β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma. J Biol Chem (2012) 0.89
Mechanical interplay between invadopodia and the nucleus in cultured cancer cells. Sci Rep (2015) 0.89
Microdomains in forebrain spines: an ultrastructural perspective. Mol Neurobiol (2012) 0.89
Phosphorylation of Ser 402 impedes phosphatase activity of slingshot 1. EMBO Rep (2011) 0.87
ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival. Cell Rep (2015) 0.87
Allele-specific effects of human deafness gamma-actin mutations (DFNA20/26) on the actin/cofilin interaction. J Biol Chem (2009) 0.86
Brefeldin A-inhibited ADP-ribosylation factor activator BIG2 regulates cell migration via integrin β1 cycling and actin remodeling. Proc Natl Acad Sci U S A (2012) 0.84
Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons. Mol Biol Cell (2012) 0.84
Phosphatidylinositol (4,5)-bisphosphate regulation of N-methyl-D-aspartate receptor channels in cortical neurons. Mol Pharmacol (2009) 0.84
Regulation of osteoclasts by membrane-derived lipid mediators. Cell Mol Life Sci (2013) 0.83
Redox regulation of 14-3-3ζ controls monocyte migration. Arterioscler Thromb Vasc Biol (2014) 0.80
MEK signalling tunes actin treadmilling for interstitial lymphocyte migration. EMBO J (2010) 0.79
Double-stranded RNA-dependent protein kinase regulates the motility of breast cancer cells. PLoS One (2012) 0.78
Stress as a possible mechanism in melanoma progression. Dermatol Res Pract (2010) 0.77
Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin. J Cell Sci (2014) 0.77
Regulation of pulmonary endothelial barrier function by kinases. Am J Physiol Lung Cell Mol Physiol (2016) 0.76
Mouse Genetic Models of Human Brain Disorders. Front Genet (2016) 0.76
Epithelial microfilament regulators show regional distribution in mouse conjunctiva. Mol Vis (2010) 0.76
Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics. J Biol Chem (2014) 0.76
Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays. Sci Rep (2015) 0.76
Observation and kinematic description of long actin tracks induced by spherical beads. Biophys J (2010) 0.76
Microfabricated Systems and Assays for Studying the Cytoskeletal Organization, Micromechanics, and Motility Patterns of Cancerous Cells. Adv Mater Interfaces (2014) 0.75
The Zuo Jin Wan Formula Induces Mitochondrial Apoptosis of Cisplatin-Resistant Gastric Cancer Cells via Cofilin-1. Evid Based Complement Alternat Med (2016) 0.75
Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration. Sci Rep (2016) 0.75
Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels. Proc Natl Acad Sci U S A (2015) 0.75
MIEN1 drives breast tumor cell migration by regulating cytoskeletal-focal adhesion dynamics. Oncotarget (2016) 0.75
Selection of genes associated with variations in the Circle of Willis in gerbils using suppression subtractive hybridization. PLoS One (2015) 0.75
The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions. PLoS Genet (2016) 0.75
Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing. Mol Cell Proteomics (2015) 0.75
Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation. Sci Rep (2017) 0.75
Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex. Neoplasia (2017) 0.75
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res (2004) 7.56
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res (2007) 6.60
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
Intravital imaging of metastatic behavior through a mammary imaging window. Nat Methods (2008) 4.13
Cell migration in tumors. Curr Opin Cell Biol (2005) 3.88
The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer (2007) 3.71
Cofilin produces newly polymerized actin filaments that are preferred for dendritic nucleation by the Arp2/3 complex. Curr Biol (2002) 3.06
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J Cell Biol (2009) 2.90
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A (2010) 2.89
Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol (2006) 2.86
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol (2004) 2.55
Probing the microenvironment of mammary tumors using multiphoton microscopy. J Mammary Gland Biol Neoplasia (2006) 2.40
Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland. Dev Dyn (2006) 2.35
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. Curr Biol (2011) 2.34
Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. J Cell Biol (2007) 2.26
Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis. Cancer Res (2006) 2.17
Directed cell invasion and migration during metastasis. Curr Opin Cell Biol (2011) 2.12
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J Cell Sci (2002) 2.11
Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia (2007) 2.03
Visualization of mRNA translation in living cells. J Cell Biol (2006) 2.03
The cofilin activity cycle in lamellipodia and invadopodia. J Cell Biochem (2009) 1.99
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy. BMC Biotechnol (2005) 1.93
Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Curr Biol (2004) 1.91
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci (2004) 1.89
N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors. J Cell Sci (2012) 1.84
Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J Exp Med (2013) 1.77
Invadopodia and podosomes in tumor invasion. Eur J Cell Biol (2005) 1.75
An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. Cancer Res (2011) 1.75
WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells. J Cell Biol (2008) 1.73
Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging. Nat Protoc (2011) 1.67
Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding. J Cell Biol (2008) 1.61
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Mol Biol Cell (2002) 1.60
N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells. Cell Motil Cytoskeleton (2009) 1.54
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia. J Cell Sci (2010) 1.53
High-resolution multiphoton imaging of tumors in vivo. Cold Spring Harb Protoc (2011) 1.52
A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J Cell Sci (2009) 1.45
Metastasis: tumor cells becoming MENAcing. Trends Cell Biol (2010) 1.44
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol (2011) 1.38
A neural Wiskott-Aldrich Syndrome protein-mediated pathway for localized activation of actin polymerization that is regulated by cortactin. J Biol Chem (2004) 1.37
Dendra2 photoswitching through the Mammary Imaging Window. J Vis Exp (2009) 1.36
β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell (2013) 1.29
The PCH family member MAYP/PSTPIP2 directly regulates F-actin bundling and enhances filopodia formation and motility in macrophages. Mol Biol Cell (2005) 1.22
Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation. Cell Motil Cytoskeleton (2004) 1.21
Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide. Am J Trop Med Hyg (2007) 1.20
Imaging mRNA movement from transcription sites to translation sites. Semin Cell Dev Biol (2007) 1.17
The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42. J Biol Chem (2009) 1.13
Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. J Biol Chem (2003) 1.12
Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells. Curr Biol (2013) 1.11
Ric-8 enhances G protein betagamma-dependent signaling in response to betagamma-binding peptides in intact cells. Mol Pharmacol (2005) 1.07
Structure of the prolidase from Pyrococcus furiosus. Biochemistry (2004) 1.06
Contribution of CXCL12 secretion to invasion of breast cancer cells. Breast Cancer Res (2012) 1.05
Regulatory interactions between the amino terminus of G-protein betagamma subunits and the catalytic domain of phospholipase Cbeta2. J Biol Chem (2004) 1.05
Cell motility: insights from the backstage. Nat Cell Biol (2002) 1.03
Description and characterization of a chamber for viewing and quantifying cancer cell chemotaxis. Cell Motil Cytoskeleton (2005) 1.03
Imaging tumor cell movement in vivo. Curr Protoc Cell Biol (2007) 1.02
Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in liquid chromatography-multiple reaction monitoring-MS (LC-MRM-MS). Mol Cell Proteomics (2013) 1.01
Microenvironments dictating tumor cell dormancy. Recent Results Cancer Res (2012) 1.01
Moving in the right direction-nanoimaging in cancer cell motility and metastasis. Microsc Res Tech (2007) 1.00
Quantification of PtdIns(3,4,5)P(3) dynamics in EGF-stimulated carcinoma cells: a comparison of PH-domain-mediated methods with immunological methods. Biochem J (2008) 0.99
The therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injury. PLoS One (2012) 0.97
Visualization of actin polymerization in invasive structures of macrophages and carcinoma cells using photoconvertible β-actin-Dendra2 fusion proteins. PLoS One (2011) 0.96
Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK. Am J Pathol (2009) 0.96
Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion. J Cell Sci (2011) 0.95
Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes. Eur J Cell Biol (2010) 0.95
Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering. Mol Biol Cell (2009) 0.94
Stretching the timescale of intravital imaging in tumors. Cell Adh Migr (2009) 0.94
Advantages of delaying the onset of rehabilitative reaching training in rats with incomplete spinal cord injury. Eur J Neurosci (2009) 0.92
In vivo assay for tumor cell invasion. Methods Mol Biol (2009) 0.92
High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis. Methods Mol Biol (2013) 0.91
A temporal model of cofilin regulation and the early peak of actin barbed ends in invasive tumor cells. Biophys J (2011) 0.90
Spatial regulation of RhoC activity defines protrusion formation in migrating cells. J Cell Sci (2013) 0.90
N-WASP has the ability to compensate for the loss of WASP in macrophage podosome formation and chemotaxis. Exp Cell Res (2010) 0.88
Imaging of gene expression in living cells and tissues. J Biomed Opt (2005) 0.88
Suspension matrices for improved Schwann-cell survival after implantation into the injured rat spinal cord. J Neurotrauma (2010) 0.88
Rapid chemokinetic movement and the invasive potential of lung cancer cells; a functional molecular study. BMC Cancer (2006) 0.87
Imaging tumor cell movement in vivo. Curr Protoc Cell Biol (2013) 0.83
Modeling the synergy of cofilin and Arp2/3 in lamellipodial protrusive activity. Biophys J (2013) 0.81
Live cell imaging of RhoGTPase biosensors in tumor cells. Methods Mol Biol (2013) 0.80
The use of fluorescent proteins for intravital imaging of cancer cell invasion. Methods Mol Biol (2012) 0.79
MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma. Arch Pathol Lab Med (2015) 0.79
Dose and chemical modification considerations for continuous cyclic AMP analog delivery to the injured CNS. J Neurotrauma (2009) 0.78
The in vivo invasion assay: preparation and handling of collection needles. Cold Spring Harb Protoc (2011) 0.78