Published in J Cell Sci on June 01, 2005
RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. Science (2015) 3.49
Subcellular mRNA localization in animal cells and why it matters. Science (2009) 2.54
Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. J Cell Biol (2007) 2.26
Visualization of mRNA translation in living cells. J Cell Biol (2006) 2.03
Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Nature (2008) 1.98
Remote control of gene function by local translation. Cell (2014) 1.72
Water permeation drives tumor cell migration in confined microenvironments. Cell (2014) 1.69
Regulation of cell migration by dynamic microtubules. Semin Cell Dev Biol (2011) 1.64
The retrovirus RNA trafficking granule: from birth to maturity. Retrovirology (2006) 1.63
Arp2/3 complex regulates asymmetric division and cytokinesis in mouse oocytes. PLoS One (2011) 1.34
Mechanisms and cellular roles of local protein synthesis in mammalian cells. Curr Opin Cell Biol (2008) 1.31
Neuronal mRNAs travel singly into dendrites. Proc Natl Acad Sci U S A (2012) 1.25
Principles and roles of mRNA localization in animal development. Development (2012) 1.23
β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration. Genes Dev (2012) 1.13
ZBP1 enhances cell polarity and reduces chemotaxis. J Cell Sci (2007) 1.11
STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines. Br J Cancer (2006) 1.08
Single mRNA tracking in live cells. Methods Enzymol (2010) 1.07
RNA localization and polarity: from A(PC) to Z(BP). Trends Cell Biol (2009) 1.07
Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells. BMC Cell Biol (2006) 1.05
A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation. J Pathol (2008) 1.01
mRNA detection of individual cells with the single cell nanoprobe method compared with in situ hybridization. J Nanobiotechnology (2007) 1.00
Analysis of the kinetics of transcription and replication of the rotavirus genome by RNA interference. J Virol (2009) 0.96
Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function. Transl Res (2011) 0.96
mRNA localization: an orchestration of assembly, traffic and synthesis. Traffic (2012) 0.94
Single molecule fluorescence approaches shed light on intracellular RNAs. Chem Rev (2014) 0.94
Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells. J Cell Sci (2009) 0.93
A quantitative evaluation of peroxidase inhibitors for tyramide signal amplification mediated cytochemistry and histochemistry. Histochem Cell Biol (2006) 0.93
An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho-GTP. J Cell Sci (2011) 0.93
A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila. Genetics (2007) 0.92
Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes. Elife (2016) 0.92
Analogue encoding of physicochemical properties of proteins in their cognate messenger RNAs. Nat Commun (2013) 0.91
Mis-localization of Arp2 mRNA impairs persistence of directional cell migration. Exp Cell Res (2010) 0.91
Actin binding proteins: their ups and downs in metastatic life. Cell Adh Migr (2013) 0.90
Rotavirus prevents the expression of host responses by blocking the nucleocytoplasmic transport of polyadenylated mRNAs. J Virol (2013) 0.89
Regulation of protein levels in subcellular domains through mRNA transport and localized translation. Mol Cell Proteomics (2010) 0.89
hnRNP Q regulates Cdc42-mediated neuronal morphogenesis. Mol Cell Biol (2012) 0.89
Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions. Dev Cell (2015) 0.87
LPA-induced mutually exclusive subcellular localization of active RhoA and Arp2 mRNA revealed by sequential FRET and FISH. Histochem Cell Biol (2009) 0.84
Molecular insights into intracellular RNA localization. Int Rev Cell Mol Biol (2013) 0.84
Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions. J Biol Chem (2008) 0.83
The Relationship between Dendritic Branch Dynamics and CPEB-Labeled RNP Granules Captured in Vivo. Front Neural Circuits (2009) 0.83
Direct RNA sequencing mediated identification of mRNA localized in protrusions of human MDA-MB-231 metastatic breast cancer cells. J Mol Signal (2013) 0.82
Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiae. PLoS One (2012) 0.80
Control of cell migration through mRNA localization and local translation. Wiley Interdiscip Rev RNA (2014) 0.79
Here, there, everywhere. mRNA localization in budding yeast. RNA Biol (2014) 0.79
Post-transcriptional control of gene expression in mouse early embryo development: a view from the tip of the iceberg. Genes (Basel) (2011) 0.78
Arp2/3 complex inhibition prevents meiotic maturation in porcine oocytes. PLoS One (2014) 0.77
Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification. Chem Sci (2017) 0.76
Genomic analysis of RNA localization. RNA Biol (2014) 0.76
Gag-dependent enrichment of HIV-1 RNA near the uropod membrane of polarized T cells. J Virol (2013) 0.76
How and why does Dia1 mRNA localize? Commun Integr Biol (2011) 0.76
Immediate translation of Formin DIAPH1 mRNA after its exiting the nucleus is required for its perinuclear localization in fibroblasts. PLoS One (2013) 0.76
Targeting Microtubules for Wound Repair. Adv Wound Care (New Rochelle) (2016) 0.75
Production of Xenopus tropicalis egg extracts to identify microtubule-associated RNAs. J Vis Exp (2013) 0.75
Localizing cellular housekeeping. Nat Rev Mol Cell Biol (2011) 0.75
RNP transport in cell biology: the long and winding road. Curr Opin Cell Biol (2017) 0.75
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (2003) 12.41
Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu Rev Biophys Biomol Struct (2000) 10.11
The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci U S A (1998) 9.33
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Curr Biol (2003) 6.66
Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype. J Cell Biol (1994) 6.33
Characterization of a beta-actin mRNA zipcode-binding protein. Mol Cell Biol (1997) 5.21
Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell (1986) 4.53
The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. J Cell Biol (1997) 4.34
The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. EMBO J (1988) 4.19
The intracellular localization of messenger RNAs. Cell (1995) 3.87
Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments. J Cell Biol (1993) 3.49
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J Biol Chem (1987) 3.20
Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba. J Cell Biol (1997) 3.11
Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions. Nature (1998) 2.61
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. Cell (2004) 2.57
Requirement of microfilaments in sorting of actin messenger RNA. Science (1991) 2.53
RNA on the move: the mRNA localization pathway. J Cell Biol (1993) 2.52
Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. Development (1989) 2.50
Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo. Curr Biol (1999) 2.45
beta-Actin messenger RNA localization and protein synthesis augment cell motility. J Cell Biol (1997) 2.43
The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility. Proc Natl Acad Sci U S A (2001) 2.40
Signaling to actin dynamics. J Cell Biol (1999) 2.26
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol (2002) 2.20
Microtubules mediate the localization of bicoid RNA during Drosophila oogenesis. Development (1991) 2.16
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation. J Cell Biol (1999) 2.14
Protein translation components are colocalized in granules in oligodendrocytes. J Cell Sci (1995) 2.13
Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins. Biochem J (1997) 2.12
Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. Cell (2001) 2.06
Beta-actin mRNA localization is regulated by signal transduction mechanisms. J Cell Biol (1994) 2.01
The travels of mRNAs through all cells large and small. FASEB J (1999) 1.84
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol (2002) 1.77
The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension. Curr Biol (2001) 1.62
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions. Mol Biol Cell (2002) 1.60
Effect of protein kinase inhibitor H-7 on the contractility, integrity, and membrane anchorage of the microfilament system. Cell Motil Cytoskeleton (1994) 1.51
2,3-Butanedione monoxime (BDM) as a myosin inhibitor. J Muscle Res Cell Motil (2002) 1.45
A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts. Curr Biol (2001) 1.28
Localization of actin messenger RNA during early ascidian development. Dev Biol (1983) 1.25
Apical localization of wingless transcripts is required for wingless signaling. Cell (2001) 1.22
Sorting of messenger RNAs in the cytoplasm: mRNA localization and the cytoskeleton. Exp Cell Res (1996) 1.09
Sensitive mRNA detection by fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification. J Histochem Cytochem (1998) 1.09
Use of oligodeoxynucleotide probes for quantitative in situ hybridization to actin mRNA. Anal Biochem (1987) 0.95
Detection and localization of actin mRNA isoforms in chicken muscle cells by in situ hybridization using biotinated oligonucleotide probes. J Cell Biochem (1990) 0.90
From silencing to gene expression: real-time analysis in single cells. Cell (2004) 7.73
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res (2004) 7.56
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res (2007) 6.60
Transcriptional pulsing of a developmental gene. Curr Biol (2006) 6.35
In vivo dynamics of RNA polymerase II transcription. Nat Struct Mol Biol (2007) 6.10
Single-RNA counting reveals alternative modes of gene expression in yeast. Nat Struct Mol Biol (2008) 6.09
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature (2005) 5.29
Single-cell gene expression profiling. Science (2002) 5.07
Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A (2004) 4.89
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med (2007) 4.63
Dynamics of single mRNPs in nuclei of living cells. Science (2004) 4.58
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
Intravital imaging of metastatic behavior through a mammary imaging window. Nat Methods (2008) 4.13
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res (2004) 4.04
Automatic clustering of orthologs and inparalogs shared by multiple proteomes. Bioinformatics (2006) 3.98
Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res (2002) 3.95
Cell migration in tumors. Curr Opin Cell Biol (2005) 3.88
Gene expression and the myth of the average cell. Trends Cell Biol (2003) 3.78
The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer (2007) 3.71
Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (2011) 3.67
Anatase TiO2 single crystals with a large percentage of reactive facets. Nature (2008) 3.66
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell (2013) 3.32
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
Fluorescence in situ hybridization: past, present and future. J Cell Sci (2003) 3.20
Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study. Ophthalmology (2004) 3.14
Cofilin produces newly polymerized actin filaments that are preferred for dendritic nucleation by the Arp2/3 complex. Curr Biol (2002) 3.06
The great escape: when cancer cells hijack the genes for chemotaxis and motility. Annu Rev Cell Dev Biol (2005) 2.97
Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell (2011) 2.92
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J Cell Biol (2009) 2.90
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A (2010) 2.89
Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol (2006) 2.86
Caribbean corals in crisis: record thermal stress, bleaching, and mortality in 2005. PLoS One (2010) 2.69
Visualization of single molecules of mRNA in situ. Methods Enzymol (2003) 2.62
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study. Can J Cardiol (2013) 2.60
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol (2004) 2.55
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners. Nat Cell Biol (2006) 2.52
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat (2007) 2.49
Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol (2003) 2.45
Probing the microenvironment of mammary tumors using multiphoton microscopy. J Mammary Gland Biol Neoplasia (2006) 2.40
How and why does beta-actin mRNA target? Biol Cell (2005) 2.38
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition. Mol Biol Cell (2005) 2.36
Macrophages promote collagen fibrillogenesis around terminal end buds of the developing mammary gland. Dev Dyn (2006) 2.35
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. Curr Biol (2011) 2.34
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons. J Neurosci (2003) 2.34
Gene expression profiling of human lung tissue from smokers with severe emphysema. Am J Respir Cell Mol Biol (2004) 2.33
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. J Clin Invest (2010) 2.29
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization. J Neurosci (2003) 2.28
A transgenic mouse for in vivo detection of endogenous labeled mRNA. Nat Methods (2011) 2.27
Cofilin takes the lead. J Cell Sci (2005) 2.27
Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. J Cell Biol (2007) 2.26
The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Mol Biol Cell (2008) 2.25
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol (2008) 2.23
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol (2002) 2.20
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biol (2007) 2.20
Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (2014) 2.20
Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure (2008) 2.17
Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis. Cancer Res (2006) 2.17
In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature (2010) 2.16
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 2.15
Directed cell invasion and migration during metastasis. Curr Opin Cell Biol (2011) 2.12
The structure of ferrihydrite, a nanocrystalline material. Science (2007) 2.11
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge. J Cell Sci (2002) 2.11
Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. BMC Genomics (2008) 2.11
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol (2006) 2.09
Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA. Mol Cell (2002) 2.08
A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev (2004) 2.05
Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization. Curr Biol (2003) 2.04
Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia (2007) 2.03
Visualization of mRNA translation in living cells. J Cell Biol (2006) 2.03
Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res (2007) 2.02
The cofilin activity cycle in lamellipodia and invadopodia. J Cell Biochem (2009) 1.99
Recent tobacco tax rate adjustment and its potential impact on tobacco control in China. Tob Control (2009) 1.95
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy. BMC Biotechnol (2005) 1.93
Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Curr Biol (2004) 1.91
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension. J Cell Sci (2004) 1.89
ZBP1 regulates mRNA stability during cellular stress. J Cell Biol (2006) 1.84
Fully automated, sequential tilt-series acquisition with Leginon. J Struct Biol (2009) 1.84
N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors. J Cell Sci (2012) 1.84
Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci Transl Med (2010) 1.84
Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single center. Nephrol Dial Transplant (2011) 1.82
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. J Neurosci (2006) 1.80
Transcription of functionally related constitutive genes is not coordinated. Nat Struct Mol Biol (2010) 1.78
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol (2002) 1.77
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury. Am J Respir Crit Care Med (2009) 1.77
Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J Exp Med (2013) 1.77
Imaging transcription in living cells. Annu Rev Biophys (2009) 1.76
Invadopodia and podosomes in tumor invasion. Eur J Cell Biol (2005) 1.75
Gemcitabine in the chemoradiotherapy for locally advanced pancreatic cancer: a meta-analysis. Radiother Oncol (2011) 1.75
An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. Cancer Res (2011) 1.75
HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am J Physiol Cell Physiol (2010) 1.75