Published in Nat Immunol on December 26, 2004
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity (2007) 3.54
DNA methylation dynamics in health and disease. Nat Struct Mol Biol (2013) 2.58
An epigenetic signature for monoallelic olfactory receptor expression. Cell (2011) 2.56
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol (2008) 2.40
PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks. Mutat Res (2008) 2.31
Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. Nat Immunol (2012) 2.16
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Mol Cell Biol (2005) 2.07
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol (2009) 1.98
Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. Nat Immunol (2008) 1.78
Roles of the NF-kappaB pathway in lymphocyte development and function. Cold Spring Harb Perspect Biol (2009) 1.63
Chromatin architecture and the generation of antigen receptor diversity. Cell (2009) 1.59
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity (2008) 1.43
Interferon regulatory factor 4 and 8 in B-cell development. Trends Immunol (2008) 1.41
Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells. Nat Immunol (2008) 1.24
Allelic exclusion of immunoglobulin genes: models and mechanisms. Immunol Rev (2010) 1.17
Functional analysis of histone methyltransferase g9a in B and T lymphocytes. J Immunol (2008) 1.12
Ikaros controls isotype selection during immunoglobulin class switch recombination. J Exp Med (2009) 1.10
Monoallelic gene expression in mammals. Chromosoma (2009) 1.08
Allelic inactivation of rDNA loci. Genes Dev (2009) 1.04
A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location. J Immunol (2011) 1.03
The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling. J Immunol (2009) 1.01
Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination. EMBO J (2013) 1.01
Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci. J Exp Med (2006) 1.01
Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development. Proc Natl Acad Sci U S A (2008) 0.98
Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion. EMBO J (2007) 0.94
Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus. Proc Natl Acad Sci U S A (2008) 0.93
Epigenetic control of recombination in the immune system. Semin Immunol (2010) 0.91
Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers. Cell Rep (2013) 0.90
Clonal allelic predetermination of immunoglobulin-κ rearrangement. Nature (2012) 0.89
Nuclear compartmentalization of odorant receptor genes. Proc Natl Acad Sci U S A (2014) 0.87
Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions. PLoS Biol (2014) 0.85
A reappraisal of evidence for probabilistic models of allelic exclusion. Proc Natl Acad Sci U S A (2008) 0.85
Epigenetic regulation of antigen receptor gene rearrangement. Curr Opin Immunol (2011) 0.85
An autoregulatory mechanism imposes allosteric control on the V(D)J recombinase by histone H3 methylation. Cell Rep (2014) 0.84
Combined immunofluorescence and DNA FISH on 3D-preserved interphase nuclei to study changes in 3D nuclear organization. J Vis Exp (2013) 0.84
Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes. Front Immunol (2014) 0.82
Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'. Immunology (2013) 0.82
Heterochromatin as an incubator for pathology and treatment non-response: implication for neuropsychiatric illness. Pharmacogenomics J (2012) 0.81
Epigenetic histone modifications do not control Igkappa locus contraction and intranuclear localization in cells with dual B cell-macrophage potential. J Immunol (2006) 0.81
Ikaros in B cell development and function. World J Biol Chem (2011) 0.81
Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation. Cell Rep (2016) 0.80
The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails. Dev Comp Immunol (2008) 0.80
Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes. Mol Immunol (2007) 0.80
Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA. Mol Cytogenet (2009) 0.80
Control of V(D)J Recombination through Transcriptional Elongation and Changes in Locus Chromatin Structure and Nuclear Organization. Genet Res Int (2011) 0.80
High resolution analysis of the chromatin landscape of the IgE switch region in human B cells. PLoS One (2011) 0.79
Epigenetics of antigen-receptor gene assembly. Curr Opin Genet Dev (2007) 0.79
A novel pax5-binding regulatory element in the igκ locus. Front Immunol (2014) 0.79
The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination. Mol Cell Biol (2013) 0.78
HP-1γ Controls High-Affinity Antibody Response to T-Dependent Antigens. Front Immunol (2014) 0.77
Sequestration within nuclear chromocenters is not a requirement for silencing olfactory receptor transcription in a placode-derived cell line. Nucleus (2014) 0.76
A developmentally controlled competitive STAT5-PU.1 DNA binding mechanism regulates activity of the Ig κ E3' enhancer. J Immunol (2012) 0.76
Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males. BMC Med Genomics (2010) 0.76
Temporal and spatial regulation of V(D)J recombination: interactions of extrinsic factors with the RAG complex. Adv Exp Med Biol (2009) 0.76
Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoire. BMC Immunol (2014) 0.76
Nuclear location and the control of developmental progression. Curr Opin Genet Dev (2012) 0.76
Immunoglobulin kappa enhancers are differentially regulated at the level of chromatin structure. Mol Immunol (2007) 0.75
Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci. Nucleic Acids Res (2015) 0.75
H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase. Proc Natl Acad Sci U S A (2017) 0.75
A move to exclude. Nat Immunol (2005) 0.75
Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity (2003) 21.56
Development of monocytes, macrophages, and dendritic cells. Science (2010) 12.86
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci (2005) 11.55
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet (2006) 10.47
VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell (2006) 9.32
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science (2005) 8.97
Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci (2006) 8.25
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2012) 6.18
A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science (2005) 5.88
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods (2005) 5.59
Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity (2009) 5.43
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med (2008) 5.42
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol (2006) 5.16
Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat Genet (2006) 4.97
Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J Exp Med (2006) 4.91
Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science (2014) 4.91
Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell (2003) 4.50
In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med (2005) 4.34
MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One (2006) 4.29
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat Med (2002) 4.02
Developmental programming of CpG island methylation profiles in the human genome. Nat Struct Mol Biol (2009) 3.96
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol (2005) 3.75
Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. PLoS Med (2009) 3.68
Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev (2004) 3.66
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity (2012) 3.18
Distinct differentiation potential of blood monocyte subsets in the lung. J Immunol (2007) 3.16
Recombination centres and the orchestration of V(D)J recombination. Nat Rev Immunol (2011) 3.12
Yin Yang 1 is a critical regulator of B-cell development. Genes Dev (2007) 3.06
The role of DNA methylation in setting up chromatin structure during development. Nat Genet (2003) 3.06
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes. J Exp Med (2004) 2.68
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity (2011) 2.61
DNA methylation dynamics in health and disease. Nat Struct Mol Biol (2013) 2.58
Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J Immunol (2007) 2.55
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52
Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches. Nat Immunol (2008) 2.33
Programming of DNA methylation patterns. Annu Rev Biochem (2012) 2.32
Alveolar type II epithelial cells present antigen to CD4(+) T cells and induce Foxp3(+) regulatory T cells. Am J Respir Crit Care Med (2008) 2.15
Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus. Immunity (2013) 2.08
CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen. Immunity (2006) 2.06
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome. Immunity (2008) 2.04
The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system. FASEB J (2006) 2.04
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation. Nat Neurosci (2013) 2.03
Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria. Nat Rev Immunol (2010) 2.02
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol (2009) 1.98
CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells. Proc Natl Acad Sci U S A (2010) 1.94
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. J Exp Med (2008) 1.92
Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation. EMBO J (2004) 1.90
DNA replication timing of the human beta-globin domain is controlled by histone modification at the origin. Genes Dev (2008) 1.89
Transepithelial pathogen uptake into the small intestinal lamina propria. J Immunol (2006) 1.88
Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Blood (2012) 1.82
Uterine DCs are crucial for decidua formation during embryo implantation in mice. J Clin Invest (2008) 1.82
Establishment of transcriptional competence in early and late S phase. Nature (2002) 1.81
Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages. J Exp Med (2011) 1.80
Replicating by the clock. Nat Rev Mol Cell Biol (2003) 1.79
Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J Clin Invest (2006) 1.78
Monocytes: subsets, origins, fates and functions. Curr Opin Hematol (2010) 1.77
Three pathways to mature macrophages in the early mouse yolk sac. Blood (2005) 1.76
CKIα ablation highlights a critical role for p53 in invasiveness control. Nature (2011) 1.72
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nat Immunol (2007) 1.68
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med (2007) 1.68
A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element. J Biol Chem (2002) 1.67
In vivo structure/function and expression analysis of the CX3C chemokine fractalkine. Blood (2011) 1.63
Epigenetics of haematopoietic cell development. Nat Rev Immunol (2011) 1.58
Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation. Eur J Immunol (2011) 1.56
Lung dendritic cells rapidly mediate anthrax spore entry through the pulmonary route. J Immunol (2007) 1.56
Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J Clin Invest (2007) 1.51
Origins and tissue-context-dependent fates of blood monocytes. Immunol Cell Biol (2008) 1.50
Intestinal macrophages: well educated exceptions from the rule. Trends Immunol (2013) 1.47
Role of DNA methylation in stable gene repression. J Biol Chem (2007) 1.45
CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells. J Immunol (2005) 1.44
Distinct in vivo dendritic cell activation by live versus killed Listeria monocytogenes. Eur J Immunol (2005) 1.40
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest (2011) 1.39
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat Immunol (2012) 1.38
Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells. Proc Natl Acad Sci U S A (2007) 1.35
Monoallelic gene expression: a repertoire of recurrent themes. Immunol Rev (2004) 1.32
Defining dendritic cells by conditional and constitutive cell ablation. Immunol Rev (2010) 1.31
Macrophages: development and tissue specialization. Annu Rev Immunol (2015) 1.30
Microglia, seen from the CX3CR1 angle. Front Cell Neurosci (2013) 1.30
Shifts in replication timing actively affect histone acetylation during nucleosome reassembly. Mol Cell (2009) 1.27
The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nat Cell Biol (2012) 1.27
The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium. Invest Ophthalmol Vis Sci (2007) 1.24
Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance. Infect Immun (2006) 1.23
Silence of the genes--mechanisms of long-term repression. Nat Rev Genet (2005) 1.23
The imprinting mechanism of the Prader-Willi/Angelman regional control center. EMBO J (2002) 1.22
Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense. Immunol Cell Biol (2013) 1.20
The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles. J Immunol (2005) 1.19
CTCF elements direct allele-specific undermethylation at the imprinted H19 locus. Curr Biol (2004) 1.18
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells. Immunity (2012) 1.17
Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns. J Invest Dermatol (2006) 1.17
On-site education of VEGF-recruited monocytes improves their performance as angiogenic and arteriogenic accessory cells. J Exp Med (2013) 1.14
Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses. J Immunol (2007) 1.13
A stepwise epigenetic process controls immunoglobulin allelic exclusion. Nat Rev Immunol (2004) 1.13
Coupled pre-mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli. Mol Syst Biol (2011) 1.13
Choreography of Ig allelic exclusion. Curr Opin Immunol (2008) 1.07