Published in Mol Cell on January 07, 2005
Epidermal barrier formation and recovery in skin disorders. J Clin Invest (2006) 4.14
An accurate and interpretable model for siRNA efficacy prediction. BMC Bioinformatics (2006) 2.46
Kinase requirements in human cells: I. Comparing kinase requirements across various cell types. Proc Natl Acad Sci U S A (2008) 1.95
A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. EMBO J (2006) 1.71
Criteria for effective design, construction, and gene knockdown by shRNA vectors. BMC Biotechnol (2006) 1.60
RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. Mol Biol Cell (2006) 1.49
Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20. EMBO J (2006) 1.49
Retracted Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J (2007) 1.42
Resveratrol inhibits insulin responses in a SirT1-independent pathway. Biochem J (2006) 1.30
How golden is silence? Teaching undergraduates the power and limits of RNA interference. CBE Life Sci Educ (2006) 1.27
Quantum dots to monitor RNAi delivery and improve gene silencing. Nucleic Acids Res (2005) 1.26
Essential role of obscurin in cardiac myofibrillogenesis and hypertrophic response: evidence from small interfering RNA-mediated gene silencing. Histochem Cell Biol (2005) 1.14
Kinase requirements in human cells: IV. Differential kinase requirements in cervical and renal human tumor cell lines. Proc Natl Acad Sci U S A (2008) 1.12
A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. J RNAi Gene Silencing (2005) 1.06
Jumonji domain-containing protein 3 regulates histone 3 lysine 27 methylation during bovine preimplantation development. Proc Natl Acad Sci U S A (2012) 1.03
Large-scale production of dsRNA and siRNA pools for RNA interference utilizing bacteriophage phi6 RNA-dependent RNA polymerase. RNA (2007) 1.01
Multiplexing siRNAs to compress RNAi-based screen size in human cells. Nucleic Acids Res (2007) 0.98
Functional mapping of disease susceptibility loci using cell biology. Proc Natl Acad Sci U S A (2006) 0.89
A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells. Nucleic Acids Res (2009) 0.85
DSIR: assessing the design of highly potent siRNA by testing a set of cancer-relevant target genes. PLoS One (2012) 0.85
Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer. Breast Cancer Res (2012) 0.83
Single cell cytometry of protein function in RNAi treated cells and in native populations. BMC Cell Biol (2008) 0.81
Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival. Mol Cell Neurosci (2013) 0.80
Multifunctional genes. Mol Syst Biol (2005) 0.79
A comparison of multiple shRNA expression methods for combinatorial RNAi. Genet Vaccines Ther (2011) 0.79
Signaling through C/EBP homologous protein and death receptor 5 and calpain activation differentially regulate THP-1 cell maturation-dependent apoptosis induced by Shiga toxin type 1. Infect Immun (2010) 0.79
Efficient and gentle siRNA delivery by magnetofection. Biotech Histochem (2010) 0.78
Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development. Cancer Lett (2013) 0.77
RORC2 gene silencing in human Th17 cells by siRNA: design and evaluation of highly efficient siRNA. Avicenna J Med Biotechnol (2013) 0.77
RNA-mediated gene silencing in hematopoietic cells. J Biomed Biotechnol (2006) 0.76
Precise and efficient siRNA design: a key point in competent gene silencing. Cancer Gene Ther (2016) 0.76
5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis. Cancer Cell Int (2012) 0.75
Novel translational strategies in colorectal cancer research. World J Gastroenterol (2007) 0.75
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A (2004) 4.85
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells. Proc Natl Acad Sci U S A (2014) 2.50
Alcohol availability as a predictor of youth drinking and driving: a hierarchical analysis of survey and archival data. Alcohol Clin Exp Res (2003) 1.94
The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol Cancer Res (2008) 1.71
Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res (2006) 1.64
p53-Dependent induction of PVT1 and miR-1204. J Biol Chem (2011) 1.56
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. J Immunol (2005) 1.54
Applications of RNA interference in mammalian systems. Annu Rev Genomics Hum Genet (2007) 1.51
RNAi microarray analysis in cultured mammalian cells. Genome Res (2003) 1.51
Pvt1-encoded microRNAs in oncogenesis. Retrovirology (2008) 1.43
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells. Mol Cancer Ther (2006) 1.41
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proc Natl Acad Sci U S A (2013) 1.36
Synthetic mimics of small Mammalian cell surface receptors. J Am Chem Soc (2004) 1.34
Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response. J Biol Chem (2009) 1.31
SpliceCenter: a suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies. BMC Bioinformatics (2008) 1.29
The 8q24 gene desert: an oasis of non-coding transcriptional activity. Front Genet (2012) 1.28
Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome. Breast Cancer Res Treat (2009) 1.27
Tobacco free workplace policies and low socioeconomic status female bartenders in San Francisco. J Epidemiol Community Health (2006) 1.21
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. Breast Cancer Res Treat (2011) 1.19
MicroRNAs and genomic instability. Semin Cancer Biol (2006) 1.14
Cisplatin sensitivity mediated by WEE1 and CHK1 is mediated by miR-155 and the miR-15 family. Cancer Res (2012) 1.11
Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther (2009) 1.11
Evaluating medical marijuana dispensary policies: spatial methods for the study of environmentally-based interventions. Am J Community Psychol (2013) 1.06
Transcription poisoning by Topoisomerase I is controlled by gene length, splice sites, and miR-142-3p. Cancer Res (2013) 1.05
Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis. Proc Natl Acad Sci U S A (2013) 1.04
Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo. Respir Res (2006) 1.03
A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G. J Am Chem Soc (2006) 1.02
Formation of biofilms by Listeria monocytogenes under various growth conditions. J Food Prot (2005) 0.98
Multiplexing siRNAs to compress RNAi-based screen size in human cells. Nucleic Acids Res (2007) 0.98
Mismatched siRNAs downregulate mRNAs as a function of target site location. FEBS Lett (2006) 0.96
A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. Int J Cancer (2011) 0.95
Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Res (2013) 0.95
Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation. Eur J Cancer (2013) 0.90
An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane. Angew Chem Int Ed Engl (2004) 0.90
Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Mol Cancer (2012) 0.89
Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res (2014) 0.88
Assessing the Validity of On-Premise Alcohol License Data in Six Communities in California: Operating Characteristics and Outlet Densities. Subst Use Misuse (2013) 0.86
Elimination of Listeria monocytogenes biofilms by ozone, chlorine, and hydrogen peroxide. J Food Prot (2005) 0.85
Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines. RNA Biol (2013) 0.85
Correlates of persistent smoking in bars subject to smokefree workplace policy. Int J Environ Res Public Health (2009) 0.84
Identification of miRNAs that modulate glucocerebrosidase activity in Gaucher disease cells. RNA Biol (2014) 0.83
Allele-specific silencing of the dominant disease allele in sialuria by RNA interference. FASEB J (2008) 0.83
Genomic instability and mouse microRNAs. Toxicol Mech Methods (2011) 0.83
Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer. Breast Cancer Res (2012) 0.83
Survival of Shigella boydii 18 in bean salad. J Food Prot (2005) 0.82
Identification of mammalian protein quality control factors by high-throughput cellular imaging. PLoS One (2012) 0.81
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines. Clin Exp Metastasis (2014) 0.80
In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo. J Gene Med (2004) 0.80
Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries. J Am Chem Soc (2004) 0.79
Power ultrasound treatment of Listeria monocytogenes in apple cider. J Food Prot (2005) 0.79
Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions. Hum Gene Ther (2005) 0.79
High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them. Methods (2012) 0.78
Inactivation of Shigella boydii 18 IDPH and Listeria monocytogenes Scott A with power ultrasound at different acoustic energy densities and temperatures. J Food Sci (2007) 0.77
Removal of Listeria monocytogenes biofilms from stainless steel by use of ultrasound and ozone. J Food Prot (2009) 0.76
RNAi quashes polyQ. Nat Med (2004) 0.75
A new approach to the inhibition of gene expression. Trends Biotechnol (2002) 0.75
Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data. Nat Commun (2016) 0.75
Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma. NAR Cancer (2022) 0.75