Published in Genome Res on October 01, 2003
MARS: microarray analysis, retrieval, and storage system. BMC Bioinformatics (2005) 2.14
DNA microarrays in herbal drug research. Evid Based Complement Alternat Med (2006) 1.70
Genetic alteration and gene expression modulation during cancer progression. Mol Cancer (2004) 1.50
Automatic nuclei segmentation in H&E stained breast cancer histopathology images. PLoS One (2013) 1.43
The potential of high-content high-throughput microscopy in drug discovery. Br J Pharmacol (2007) 1.42
RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci U S A (2004) 1.29
Functional genomics in radiation biology: a gateway to cellular systems-level studies. Radiat Environ Biophys (2007) 1.18
High-throughput analysis of signals regulating stem cell fate and function. Curr Opin Chem Biol (2007) 1.15
Substrate-mediated delivery from self-assembled monolayers: effect of surface ionization, hydrophilicity, and patterning. Acta Biomater (2005) 1.14
MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. Sci Signal (2012) 1.13
Cell-controlled and spatially arrayed gene delivery from fibrin hydrogels. Biomaterials (2009) 1.09
Localized transfection on arrays of magnetic beads coated with PCR products. Nat Methods (2005) 1.06
Quantitative analysis of highly parallel transfection in cell microarrays. Nucleic Acids Res (2004) 1.01
A cell spot microarray method for production of high density siRNA transfection microarrays. BMC Genomics (2011) 0.98
Surfection: a new platform for transfected cell arrays. Nucleic Acids Res (2004) 0.97
In situ electroporation of surface-bound siRNAs in microwell arrays. Lab Chip (2012) 0.95
Bioluminescence imaging for assessment and normalization in transfected cell arrays. Biotechnol Bioeng (2007) 0.94
Spatially and temporally controlled gene transfer by electroporation into adherent cells on plasmid DNA-loaded electrodes. Nucleic Acids Res (2004) 0.90
Highly parallel introduction of nucleic acids into mammalian cells grown in microwell arrays. Lab Chip (2009) 0.88
Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2. Neoplasia (2010) 0.88
The living microarray: a high-throughput platform for measuring transcription dynamics in single cells. BMC Genomics (2011) 0.84
Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Res (2008) 0.83
The Cancer BioChip System: a functional genomic assay for anchorage-independent three-dimensional breast cancer cell growth. Horm Cancer (2012) 0.81
Single cell cytometry of protein function in RNAi treated cells and in native populations. BMC Cell Biol (2008) 0.81
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. PLoS One (2014) 0.77
Living Cell Microarrays: An Overview of Concepts. Microarrays (Basel) (2016) 0.77
Quantifying Stochastic Noise in Cultured Circadian Reporter Cells. PLoS Comput Biol (2015) 0.76
Phenotypic MicroRNA Microarrays. Microarrays (Basel) (2013) 0.75
Knockdown of E2f1 by RNA interference impairs proliferation of rat cells in vitro. Genet Mol Biol (2010) 0.75
Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays. Microarrays (Basel) (2013) 0.75
Decoding the riddle: the dawn of RNAi for the study of gene-gene and gene-environment interactions. Environ Health Perspect (2004) 0.75
Optimizing cell arrays for accurate functional genomics. BMC Res Notes (2012) 0.75
High-throughput in situ cell electroporation microsystem for parallel delivery of single guide RNAs into mammalian cells. Sci Rep (2017) 0.75
Surface-mediated nucleic acid delivery by lipoplexes prepared in microwell arrays. Small (2013) 0.75
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
RNA interference. Nature (2002) 22.28
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature (2000) 15.98
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature (2000) 9.82
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature (2003) 7.80
Gene silencing in mammals by small interfering RNAs. Nat Rev Genet (2002) 7.80
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Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A (2001) 7.12
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet (2002) 6.26
Microarrays of cells expressing defined cDNAs. Nature (2001) 5.05
Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr Biol (2002) 3.30
Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation. Proc Natl Acad Sci U S A (1999) 3.15
RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans. Curr Biol (2001) 2.78
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev (2003) 2.76
RNA interference: the new somatic cell genetics? Cancer Cell (2002) 2.05
Clinical and functional target validation using tissue and cell microarrays. Curr Opin Chem Biol (2002) 1.02
Consortium uses RNAi to uncover genes' function. Lancet (2003) 0.81
High frequency of BRAF mutations in nevi. Nat Genet (2002) 9.95
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol (2007) 9.29
Probabilistic Boolean Networks: a rule-based uncertainty model for gene regulatory networks. Bioinformatics (2002) 6.90
Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res (2002) 5.99
Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am J Pathol (2002) 5.20
Is cross-validation valid for small-sample microarray classification? Bioinformatics (2004) 5.19
Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science (2011) 5.04
Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature (2011) 5.01
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A (2004) 4.85
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Proc Natl Acad Sci U S A (2007) 4.80
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell (2012) 4.29
Somatic STAT3 mutations in large granular lymphocytic leukemia. N Engl J Med (2012) 4.15
MicroRNA in prostate, bladder, and kidney cancer: a systematic review. Eur Urol (2011) 3.57
A simple genetic architecture underlies morphological variation in dogs. PLoS Biol (2010) 3.46
Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues. Genome Biol (2008) 3.16
Gene selection: a Bayesian variable selection approach. Bioinformatics (2003) 3.14
Are data from different gene expression microarray platforms comparable? Genomics (2004) 3.13
Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol Syst Biol (2006) 3.01
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming. Cancer Res (2006) 2.82
Coat variation in the domestic dog is governed by variants in three genes. Science (2009) 2.70
miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors. PLoS One (2011) 2.70
Identification of fusion genes in breast cancer by paired-end RNA-sequencing. Genome Biol (2011) 2.64
Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res (2005) 2.64
Integrated network analysis platform for protein-protein interactions. Nat Methods (2008) 2.63
Small-sample precision of ROC-related estimates. Bioinformatics (2010) 2.56
Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. EMBO J (2011) 2.55
Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. Nat Genet (2004) 2.44
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. Breast Cancer Res Treat (2010) 2.40
Optimal number of features as a function of sample size for various classification rules. Bioinformatics (2004) 2.37
On the organization of bioinformatics core services in biology-based research institutes. Bioinformatics (2011) 2.29
CGH-Plotter: MATLAB toolbox for CGH-data analysis. Bioinformatics (2003) 2.28
PINA v2.0: mining interactome modules. Nucleic Acids Res (2011) 2.23
Frequent truncating mutations of STAG2 in bladder cancer. Nat Genet (2013) 2.20
Ratio statistics of gene expression levels and applications to microarray data analysis. Bioinformatics (2002) 2.19
Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner. J Immunol (2009) 2.11
Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors. Genes Chromosomes Cancer (2010) 2.11
The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study. Breast Cancer Res Treat (2005) 2.10
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. Cancer Res (2011) 2.07
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
SHARPIN is an endogenous inhibitor of β1-integrin activation. Nat Cell Biol (2011) 2.01
Gene perturbation and intervention in probabilistic Boolean networks. Bioinformatics (2002) 1.98
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme. Genome Med (2010) 1.94
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia. Cancer Discov (2013) 1.93
The role of certain Post classes in Boolean network models of genetic networks. Proc Natl Acad Sci U S A (2003) 1.89
FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells. Cancer Res (2010) 1.88
SNiPer-HD: improved genotype calling accuracy by an expectation-maximization algorithm for high-density SNP arrays. Bioinformatics (2006) 1.88
Inferring gene regulatory networks from time series data using the minimum description length principle. Bioinformatics (2006) 1.85
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity (2011) 1.83
A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses. PLoS One (2010) 1.83
Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells. Cancer Res (2011) 1.82
CIP2A is associated with human breast cancer aggressivity. Clin Cancer Res (2009) 1.81
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood (2013) 1.80
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155. Nat Med (2011) 1.79
Generating Boolean networks with a prescribed attractor structure. Bioinformatics (2005) 1.78
Optimized LOWESS normalization parameter selection for DNA microarray data. BMC Bioinformatics (2004) 1.73
FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells. Cancer Res (2012) 1.72
The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol Cancer Res (2008) 1.71
Unraveling gene-gene interactions regulated by ligands of the aryl hydrocarbon receptor. Environ Health Perspect (2004) 1.70
Integrin trafficking regulated by Rab21 is necessary for cytokinesis. Dev Cell (2008) 1.70
Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer. Nat Rev Clin Oncol (2011) 1.69
High-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: impact of copy number on gene expression. Neoplasia (2004) 1.66
Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res (2006) 1.64
Relationships between probabilistic Boolean networks and dynamic Bayesian networks as models of gene regulatory networks. Signal Processing (2006) 1.61
Defining and assaying RNAi in mammalian cells. Mol Cell (2005) 1.60
Allelic imbalance at rs6983267 suggests selection of the risk allele in somatic colorectal tumor evolution. Cancer Res (2008) 1.59
Clinical validation of candidate genes associated with prostate cancer progression in the CWR22 model system using tissue microarrays. Cancer Res (2002) 1.58
Large-scale profiling of archival lymph nodes reveals pervasive remodeling of the follicular lymphoma methylome. Cancer Res (2009) 1.58
Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling. Cell (2008) 1.58
Strong feature sets from small samples. J Comput Biol (2002) 1.57
A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks. Bioinformatics (2004) 1.57
p53-Dependent induction of PVT1 and miR-1204. J Biol Chem (2011) 1.56
Gene-expression profiling predicts recurrence in Dukes' C colorectal cancer. Gastroenterology (2005) 1.56
Decorrelation of the true and estimated classifier errors in high-dimensional settings. EURASIP J Bioinform Syst Biol (2007) 1.54
Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. J Immunol (2005) 1.54
Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development. Cancer Res (2005) 1.52
Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat. Cancer Res (2004) 1.52
Imiquimod in the treatment of breast cancer skin metastasis. J Clin Oncol (2014) 1.51
Applications of RNA interference in mammalian systems. Annu Rev Genomics Hum Genet (2007) 1.51
Growing genetic regulatory networks from seed genes. Bioinformatics (2004) 1.49
Intervention in context-sensitive probabilistic Boolean networks. Bioinformatics (2004) 1.48
Inferring connectivity of genetic regulatory networks using information-theoretic criteria. IEEE/ACM Trans Comput Biol Bioinform (2008) 1.47
Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy. J Clin Invest (2015) 1.46
Efficient experimental design for uncertainty reduction in gene regulatory networks. BMC Bioinformatics (2015) 1.45
Pvt1-encoded microRNAs in oncogenesis. Retrovirology (2008) 1.43
Global gene expression profile of human cord blood-derived CD133+ cells. Stem Cells (2005) 1.42
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells. Mol Cancer Ther (2006) 1.41
Reporting bias when using real data sets to analyze classification performance. Bioinformatics (2009) 1.41
Use of IgE and IgG4 epitope binding to predict the outcome of oral immunotherapy in cow's milk allergy. Pediatr Allergy Immunol (2014) 1.41
Steady-state analysis of genetic regulatory networks modelled by probabilistic boolean networks. Comp Funct Genomics (2003) 1.39
MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer. Neoplasia (2012) 1.39
What should be expected from feature selection in small-sample settings. Bioinformatics (2006) 1.38
Intervention in gene regulatory networks via greedy control policies based on long-run behavior. BMC Syst Biol (2009) 1.38
Confidence intervals for the true classification error conditioned on the estimated error. Technol Cancer Res Treat (2006) 1.37
Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network. BMC Bioinformatics (2010) 1.36
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. Cancer Res (2007) 1.35