Published in Am J Physiol Heart Circ Physiol on January 06, 2005
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn. Am J Physiol Lung Cell Mol Physiol (2012) 0.99
Vascular TRP channels: performing under pressure and going with the flow. Physiology (Bethesda) (2014) 0.89
Oxidative stress induces gastric submucosal arteriolar dysfunction in the elderly. World J Gastroenterol (2013) 0.88
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiol Rev (2016) 0.81
CYP2C29 produces superoxide in response to shear stress. Microcirculation (2012) 0.79
Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem (1974) 15.45
Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res (2000) 10.95
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci U S A (1996) 4.20
Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation (2001) 3.54
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem (2002) 2.94
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest (2000) 2.89
Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest (2002) 2.89
Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc Natl Acad Sci U S A (2001) 2.63
Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci (1998) 2.39
Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res (2003) 2.31
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation (2003) 2.30
NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium. Am J Physiol (1994) 2.21
Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles. Circ Res (2003) 2.09
Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice. Circ Res (2003) 1.89
Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation (2002) 1.87
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. Cardiovasc Res (2003) 1.78
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am J Physiol Heart Circ Physiol (2001) 1.71
Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ Res (2002) 1.64
ADMA and oxidative stress. Atheroscler Suppl (2003) 1.56
Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology (1998) 1.52
Vascular extracellular superoxide dismutase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation (2000) 1.45
Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts. Circulation (2002) 1.19
Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice. Free Radic Biol Med (2001) 1.13
Modeling the influence of superoxide dismutase on superoxide and nitric oxide interactions, including reversible inhibition of oxygen consumption. Free Radic Biol Med (2003) 1.11
Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest (2003) 1.08
Superoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD. Am J Physiol Heart Circ Physiol (2001) 1.02
Overexpression of copper/zinc superoxide dismutase does not prevent neonatal lethality in mutant mice that lack manganese superoxide dismutase. Free Radic Biol Med (2000) 0.98
Vasomotor responses in MnSOD-deficient mice. Am J Physiol Heart Circ Physiol (2004) 0.96
Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. Arterioscler Thromb Vasc Biol (1997) 0.94
Limited exercise capacity in heterozygous manganese superoxide dismutase gene-knockout mice: roles of superoxide anion and nitric oxide. Circulation (2005) 0.93
Superoxide and nitric oxide: consequences of varying rates of production and consumption: a theoretical treatment. Free Radic Biol Med (2002) 0.90
A role for dietary copper in nitric oxide-mediated vasodilation. Microcirculation (1995) 0.86
Changes in NO bioavailability regulate cardiac O2 consumption: control by intramitochondrial SOD2 and intracellular myoglobin. Am J Physiol Heart Circ Physiol (2003) 0.82
Emergence of Porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences. J Vet Diagn Invest (2013) 6.77
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A (2005) 4.13
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res (2002) 3.51
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation (2003) 2.56
Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol (2003) 2.52
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation (2008) 2.47
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res (2008) 2.31
Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus. Circ Res (2006) 2.26
Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci (2010) 2.24
Identification of a coronary vascular progenitor cell in the human heart. Proc Natl Acad Sci U S A (2009) 2.23
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation. Am J Physiol Heart Circ Physiol (2007) 2.20
Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries. FASEB J (2003) 2.13
Hand motion classification using a multi-channel surface electromyography sensor. Sensors (Basel) (2012) 2.07
Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circ Res (2006) 1.93
Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation (2005) 1.91
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol (2008) 1.87
Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol (2006) 1.86
Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH. Am J Physiol Heart Circ Physiol (2006) 1.86
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation (2008) 1.82
eNOS uncoupling and endothelial dysfunction in aged vessels. Am J Physiol Heart Circ Physiol (2009) 1.81
D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetes. Circulation (2005) 1.78
Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart. J Mol Cell Cardiol (2006) 1.73
Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics (2004) 1.73
High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation (2003) 1.73
Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure. Cardiovasc Res (2005) 1.70
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure. Circulation (2002) 1.65
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation. Am J Physiol Lung Cell Mol Physiol (2006) 1.63
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension (2009) 1.63
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell (2007) 1.62
Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries. Am J Physiol Heart Circ Physiol (2004) 1.59
Preservation of NO production by statins in the treatment of heart failure. Cardiovasc Res (2003) 1.59
Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase. Circulation (2005) 1.55
Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries. Am J Physiol Lung Cell Mol Physiol (2003) 1.54
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure. J Mol Cell Cardiol (2004) 1.49
Hexagonal nanoporous germanium through surfactant-driven self-assembly of Zintl clusters. Nature (2006) 1.48
Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes. Am J Physiol Heart Circ Physiol (2005) 1.47
PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler Thromb Vasc Biol (2005) 1.47
Thromboxane receptor stimulation suppresses guanylate cyclase-mediated relaxation of radial arteries. Ann Thorac Surg (2006) 1.43
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. Am J Physiol Heart Circ Physiol (2003) 1.43
Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. Am J Physiol Heart Circ Physiol (2004) 1.43
Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins. Arterioscler Thromb Vasc Biol (2005) 1.42
Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade. Circ Res (2003) 1.41
Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH. Am J Physiol Heart Circ Physiol (2009) 1.38
Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities. J Biol Chem (2005) 1.33
Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol (2003) 1.32
Oxidative stress and accelerated vascular aging: implications for cigarette smoking. Front Biosci (Landmark Ed) (2009) 1.30
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol (2005) 1.29
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am J Pathol (2004) 1.28
Full-Length Genome Sequence of a Plaque-Cloned Virulent Porcine Epidemic Diarrhea Virus Isolate (USA/Iowa/18984/2013) from a Midwestern U.S. Swine Herd. Genome Announc (2013) 1.28
Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries. Am J Physiol Heart Circ Physiol (2003) 1.27
Gender-specific regulation of cardiovascular function: estrogen as key player. Microcirculation (2004) 1.25
Oxidative stress in vascular senescence: lessons from successfully aging species. Front Biosci (2008) 1.24
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor. J Mol Cell Cardiol (2009) 1.24
Enhanced cell sorting and manipulation with combined optical tweezer and microfluidic chip technologies. Lab Chip (2011) 1.24
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.23
Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function. Arterioscler Thromb Vasc Biol (2008) 1.23
Neurogenesis after traumatic brain injury. Neurosurg Clin N Am (2007) 1.22
Epoxyeicosatrienoic acids are released to mediate shear stress-dependent hyperpolarization of arteriolar smooth muscle. Circ Res (2005) 1.22
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest (2013) 1.21
Oxidant and redox signaling in vascular oxygen sensing: implications for systemic and pulmonary hypertension. Antioxid Redox Signal (2008) 1.18
Effects of hypoxia on relationships between cytosolic and mitochondrial NAD(P)H redox and superoxide generation in coronary arterial smooth muscle. Am J Physiol Heart Circ Physiol (2008) 1.16
Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice. Am J Physiol Heart Circ Physiol (2002) 1.14
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats. Am J Physiol Heart Circ Physiol (2003) 1.12
Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart. J Card Fail (2007) 1.11
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions. Arterioscler Thromb Vasc Biol (2003) 1.11
Aging enhances pressure-induced arterial superoxide formation. Am J Physiol Heart Circ Physiol (2007) 1.10
Estrogen elicits cytochrome P450--mediated flow-induced dilation of arterioles in NO deficiency: role of PI3K-Akt phosphorylation in genomic regulation. Circ Res (2003) 1.10