Published in Circ Res on January 06, 2005
Mechanical control of tissue and organ development. Development (2010) 3.18
Principles of planar polarity in animal development. Development (2011) 2.94
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
Myocardial lineage development. Circ Res (2010) 1.98
Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A (2008) 1.90
The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex. PLoS Genet (2008) 1.80
Planar cell polarity signaling in vertebrates. Bioessays (2007) 1.62
Epicardial-myocardial signaling directing coronary vasculogenesis. Circ Res (2010) 1.46
Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Proc Natl Acad Sci U S A (2007) 1.46
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development (2010) 1.26
Cardiovascular development and the colonizing cardiac neural crest lineage. ScientificWorldJournal (2007) 1.26
The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis. Development (2007) 1.23
Primary cilia in planar cell polarity regulation of the inner ear. Curr Top Dev Biol (2008) 1.23
Noncanonical frizzled signaling regulates cell polarity of growth plate chondrocytes. Development (2009) 1.22
Functional profiling of human atrial and ventricular gene expression. Pflugers Arch (2005) 1.21
Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol (2007) 1.18
Regulation of PCP by the Fat signaling pathway. Genes Dev (2013) 1.17
Shaping the mammalian auditory sensory organ by the planar cell polarity pathway. Int J Dev Biol (2007) 1.17
Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2. Development (2009) 1.14
WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development. Biol Reprod (2010) 1.12
Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development (2009) 1.10
Alternative Wnt pathways and receptors. Cold Spring Harb Perspect Biol (2012) 1.09
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol (2013) 1.09
Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development. J Clin Invest (2009) 1.09
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
Synaptic Wnt signaling-a contributor to major psychiatric disorders? J Neurodev Disord (2011) 1.06
Nitric oxide sustains long-term skeletal muscle regeneration by regulating fate of satellite cells via signaling pathways requiring Vangl2 and cyclic GMP. Stem Cells (2012) 1.00
The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circ Res (2010) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Atrioventricular valve development: new perspectives on an old theme. Differentiation (2012) 0.98
Molecular mechanism of ventricular trabeculation/compaction and the pathogenesis of the left ventricular noncompaction cardiomyopathy (LVNC). Am J Med Genet C Semin Med Genet (2013) 0.96
Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis. Dev Biol (2012) 0.96
Planar cell polarity in Drosophila. Organogenesis (2011) 0.95
Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion. Mol Biol Cell (2012) 0.94
A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell (2011) 0.93
Planar cell polarity signaling in collective cell movements during morphogenesis and disease. Curr Genomics (2012) 0.91
The role of vertebrate nonmuscle Myosin II in development and human disease. Bioarchitecture (2014) 0.90
The kidney and planar cell polarity. Curr Top Dev Biol (2012) 0.89
The importance of Wnt signaling in cardiovascular development. Pediatr Cardiol (2009) 0.88
Human embryonic stem cell-derived cardiomyocytes migrate in response to gradients of fibronectin and Wnt5a. Stem Cells Dev (2013) 0.87
Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development. PLoS Genet (2014) 0.84
Left cardiac isomerism in the Sonic hedgehog null mouse. J Anat (2009) 0.83
Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndrome. Hum Mol Genet (2014) 0.83
Imbalanced expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles. PLoS One (2014) 0.83
A point mutation in Myh10 causes major defects in heart development and body wall closure. Circ Cardiovasc Genet (2014) 0.82
Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice. Dev Dyn (2013) 0.82
In vivo studies on nonmuscle myosin II expression and function in heart development. Front Biosci (Landmark Ed) (2012) 0.81
Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H). J Anat (2009) 0.81
Planar cell polarity signaling pathway in congenital heart diseases. J Biomed Biotechnol (2011) 0.80
Planar cell polarity and the kidney. Nephrol Dial Transplant (2013) 0.78
Wnt, a driver of myocardialization? Circ Res (2005) 0.78
Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. Circ Res (2016) 0.78
The Planar Cell Polarity Transmembrane Protein Vangl2 Promotes Dendrite, Spine and Glutamatergic Synapse Formation in the Mammalian Forebrain. Mol Neuropsychiatry (2016) 0.77
Non-muscle myosin II in disease: mechanisms and therapeutic opportunities. Dis Model Mech (2015) 0.76
Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry. Mol Neuropsychiatry (2017) 0.75
Satellite Cells in Muscular Dystrophy - Lost in Polarity. Trends Mol Med (2016) 0.75
A GAL4-inducible transgenic tool kit for the in vivo modulation of Rho GTPase activity in zebrafish. Dev Dyn (2016) 0.75
DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly. Dev Biol (2015) 0.75
The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye. Dis Model Mech (2014) 0.75
Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development: possible role in convergent extension. PLoS One (2015) 0.75
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet (2005) 4.76
The genetic basis of mammalian neurulation. Nat Rev Genet (2003) 4.14
An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science (2005) 3.61
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol (2003) 3.31
The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation. Hum Mol Genet (2006) 3.06
A feasibility study of signed consent for the collection of patient identifiable information for a national paediatric clinical audit database. BMJ (2005) 2.96
FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain (2003) 2.55
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure. Development (2007) 2.45
Genetics of human neural tube defects. Hum Mol Genet (2009) 2.28
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Hum Mol Genet (2006) 2.14
Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse. Hum Mol Genet (2003) 2.11
In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A. Genesis (2005) 2.08
Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization. Circ Res (2007) 1.85
Neural tube defects. Annu Rev Neurosci (2014) 1.69
Non-cell-autonomous roles for the planar cell polarity gene Vangl2 in development of the coronary circulation. Circ Res (2008) 1.60
Folic acid prevents exencephaly in Cited2 deficient mice. Hum Mol Genet (2002) 1.55
Fetal spina bifida in a mouse model: loss of neural function in utero. J Neurosurg (2007) 1.53
Spatiotemporal analysis of programmed cell death during mouse cardiac septation. Anat Rec A Discov Mol Cell Evol Biol (2004) 1.51
Development of the vertebrate central nervous system: formation of the neural tube. Prenat Diagn (2009) 1.49
Sonic hedgehog and the molecular regulation of mouse neural tube closure. Development (2002) 1.44
Cordon-bleu is a conserved gene involved in neural tube formation. Dev Biol (2003) 1.44
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Dis Model Mech (2013) 1.34
Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function. Hum Mol Genet (2008) 1.33
The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. Hum Mol Genet (2010) 1.30
Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development (2007) 1.27
Integrity of the methylation cycle is essential for mammalian neural tube closure. Birth Defects Res A Clin Mol Teratol (2006) 1.26
Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci (2010) 1.25
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice. Dis Model Mech (2013) 1.18
Mouse models of neural tube defects: investigating preventive mechanisms. Am J Med Genet C Semin Med Genet (2005) 1.17
Abnormal folate metabolism in foetuses affected by neural tube defects. Brain (2007) 1.16
The relationship between sonic Hedgehog signaling, cilia, and neural tube defects. Birth Defects Res A Clin Mol Teratol (2010) 1.16
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet (2009) 1.16
Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model. Hum Mol Genet (2007) 1.15
Apoptosis is not required for mammalian neural tube closure. Proc Natl Acad Sci U S A (2009) 1.11
Expression pattern of glypican-4 suggests multiple roles during mouse development. Dev Dyn (2005) 1.11
Vang-like 2 and noncanonical Wnt signaling in outflow tract development. Trends Cardiovasc Med (2006) 1.09
Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia. Dev Biol (2009) 1.08
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis. Hum Mutat (2011) 1.06
Real-time optical gating for three-dimensional beating heart imaging. J Biomed Opt (2011) 1.04
Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans. Hum Mol Genet (2011) 1.03
Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet (2003) 1.02
Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol (2012) 1.01
Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant effect. Development (2004) 1.00
Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos. FEBS Lett (2006) 1.00
The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled. Dev Biol (2012) 1.00
Maternal diabetes increases the risk of caudal regression caused by retinoic acid. Diabetes (2002) 1.00
MRC-Wellcome Trust Human Developmental Biology Resource: enabling studies of human developmental gene expression. Trends Genet (2005) 0.99
Normal and abnormal development of the intrapericardial arterial trunks in humans and mice. Cardiovasc Res (2012) 0.98
Clarification of the identity of the mammalian fifth pharyngeal arch artery. Clin Anat (2012) 0.97
Dishevelled: linking convergent extension with neural tube closure. Trends Neurosci (2003) 0.96
Getting to the heart of planar cell polarity signaling. Birth Defects Res A Clin Mol Teratol (2011) 0.96
Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos. Anat Embryol (Berl) (2003) 0.95
Reduction in fragile X related 1 protein causes cardiomyopathy and muscular dystrophy in zebrafish. J Exp Biol (2009) 0.94
Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.94
Dorsoventral patterning in oesophageal atresia with tracheo-oesophageal fistula: Evidence from a new mouse model. J Pediatr Surg (2002) 0.94
Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death. Dev Biol (2009) 0.93
The genetic background of the curly tail strain confers susceptibility to folate-deficiency-induced exencephaly. Birth Defects Res A Clin Mol Teratol (2010) 0.93
Role of Sonic hedgehog in the development of the trachea and oesophagus. J Pediatr Surg (2003) 0.92
Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets. Cardiovasc Res (2013) 0.91
Understanding the causes and prevention of neural tube defects: Insights from the splotch mouse model. Birth Defects Res A Clin Mol Teratol (2009) 0.90
Grainyhead genes and mammalian neural tube closure. Birth Defects Res A Clin Mol Teratol (2008) 0.90
Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice. PLoS Genet (2012) 0.90
Cells migrating from the neural crest contribute to the innervation of the venous pole of the heart. J Anat (2007) 0.88
Neural crest cell survival is dependent on Rho kinase and is required for development of the mid face in mouse embryos. PLoS One (2012) 0.88
Cloning and characterization of Igsf9 in mouse and human: a new member of the immunoglobulin superfamily expressed in the developing nervous system. Genomics (2002) 0.88
The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development. Dev Dyn (2010) 0.88
Tethering of the spinal cord in mouse fetuses and neonates with spina bifida. J Neurosurg (2003) 0.87
EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion. Int J Dev Biol (2009) 0.87
Development of the outflow tracts with reference to aortopulmonary windows and aortoventricular tunnels. Cardiol Young (2010) 0.87
Epithelial fusion during neural tube morphogenesis. Birth Defects Res A Clin Mol Teratol (2012) 0.86
Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity. Development (2013) 0.86
Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse. Hum Mol Genet (2011) 0.86
Autonomic innervation of the developing heart: origins and function. Clin Anat (2009) 0.85
Differential protein expression at the stage of neural tube closure in the mouse embryo. J Biol Chem (2002) 0.85
Heparan sulphate proteoglycans and spinal neurulation in the mouse embryo. Development (2002) 0.84