Published in Proc Natl Acad Sci U S A on January 11, 2005
A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol Cell Biol (2006) 1.94
Role of LDB1 in the transition from chromatin looping to transcription activation. Genes Dev (2014) 1.71
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX. Proc Natl Acad Sci U S A (2007) 1.45
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res (2012) 1.38
The NuRD architecture. Cell Mol Life Sci (2013) 1.18
Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA. J Mol Biol (2008) 1.14
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell Rep (2012) 1.12
Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor. Mol Cell (2009) 1.09
GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1. Mol Cell Biol (2005) 1.05
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proc Natl Acad Sci U S A (2011) 1.00
Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease. J Virol (2007) 0.90
Transcriptional mechanisms underlying hemoglobin synthesis. Cold Spring Harb Perspect Med (2013) 0.90
The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain. J Biol Chem (2011) 0.89
Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood (2013) 0.87
CTCF terminal segments are unstructured. Protein Sci (2010) 0.79
The zinc-finger domain was essential for porcine reproductive and respiratory syndrome virus nonstructural protein-1α to inhibit the production of interferon-β. J Interferon Cytokine Res (2013) 0.78
GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA. Protein Sci (2015) 0.76
GATA factor mutations in hematologic disease. Blood (2017) 0.75
The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. PLoS One (2014) 0.75
CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function. Genes Cells (2013) 0.75
Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold. PLoS One (2013) 0.75
Haploinsufficiency for ANKRD11-flanking genes makes the difference between KBG and 16q24.3 microdeletion syndromes: 12 new cases. Eur J Hum Genet (2017) 0.75
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Protein backbone angle restraints from searching a database for chemical shift and sequence homology. J Biomol NMR (1999) 26.99
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The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data. J Biomol NMR (1994) 16.20
Torsion angle dynamics for NMR structure calculation with the new program DYANA. J Mol Biol (1997) 15.40
The atomic structure of protein-protein recognition sites. J Mol Biol (1999) 12.63
The program XEASY for computer-supported NMR spectral analysis of biological macromolecules. J Biomol NMR (1995) 12.25
HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. J Am Chem Soc (2003) 11.65
FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell (1997) 5.78
Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene (2002) 4.80
Measurement of homo- and heteronuclear J couplings from quantitative J correlation. Methods Enzymol (1994) 3.97
Structural classification of zinc fingers: survey and summary. Nucleic Acids Res (2003) 3.94
NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1. Science (1993) 3.74
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nat Genet (2000) 3.50
Multidimensional heteronuclear nuclear magnetic resonance of proteins. Methods Enzymol (1994) 3.45
GATA transcription factors: key regulators of hematopoiesis. Exp Hematol (1995) 3.09
Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev (1998) 3.00
Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin. J Mol Biol (1997) 2.77
Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex. Mol Cell (1999) 2.66
Zinc fingers are sticking together. Trends Biochem Sci (1998) 2.63
Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. EMBO J (1999) 2.21
Calculation of protein structures with ambiguous distance restraints. Automated assignment of ambiguous NOE crosspeaks and disulphide connectivities. J Mol Biol (1995) 1.93
Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila. Genes Dev (1997) 1.73
The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila. Proc Natl Acad Sci U S A (2001) 1.72
X-linked thrombocytopenia caused by a novel mutation of GATA-1. Blood (2001) 1.49
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation. Blood (2001) 1.47
Engineering a protein scaffold from a PHD finger. Structure (2003) 1.42
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction. Blood (2002) 1.41
The N-terminal zinc finger of the erythroid transcription factor GATA-1 binds GATC motifs in DNA. J Biol Chem (2001) 1.35
GATA zinc finger interactions modulate DNA binding and transactivation. J Biol Chem (2000) 1.26
Combinatorial interactions of serpent, lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis. Proc Natl Acad Sci U S A (2003) 1.12
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. J Biol Chem (2003) 1.07
The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. J Biomol NMR (1999) 1.06
Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation. Hum Mol Genet (2002) 1.03
A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped. Eur J Biochem (2000) 0.98
Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. Structure (2000) 0.95
Characterization of the conserved interaction between GATA and FOG family proteins. J Biol Chem (2002) 0.89
A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3. J Biol Chem (2004) 0.89
Modification with SUMO. A role in transcriptional regulation. EMBO Rep (2003) 3.25
Protein interactions: is seeing believing? Trends Biochem Sci (2007) 2.85
The power of two: protein dimerization in biology. Trends Biochem Sci (2004) 2.52
Hop is an unusual homeobox gene that modulates cardiac development. Cell (2002) 2.52
Sticky fingers: zinc-fingers as protein-recognition motifs. Trends Biochem Sci (2007) 2.47
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat Struct Biol (2002) 2.32
Krüppel-like transcription factors: a functional family. Int J Biochem Cell Biol (2007) 2.31
Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Am J Hum Genet (2007) 1.97
A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo. J Biol Chem (2008) 1.72
Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia. J Clin Invest (2004) 1.65
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Biochem J (2009) 1.59
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci U S A (2011) 1.56
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. J Biol Chem (2011) 1.55
Protein-protein interactions in human disease. Curr Opin Struct Biol (2005) 1.52
Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. J Biol Chem (2002) 1.48
Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells. Mol Cell Biol (2007) 1.45
Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Mol Cell Biol (2003) 1.44
Engineering a protein scaffold from a PHD finger. Structure (2003) 1.42
Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity. Plant Cell (2007) 1.41
Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin. Cell (2004) 1.39
Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proc Natl Acad Sci U S A (2006) 1.38
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proc Natl Acad Sci U S A (2012) 1.37
Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis. Mol Cell Biol (2008) 1.36
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
Role for SUMO modification in facilitating transcriptional repression by BKLF. Mol Cell Biol (2005) 1.31
Human KLF17 is a new member of the Sp/KLF family of transcription factors. Genomics (2006) 1.31
An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis. J Clin Invest (2007) 1.30
Controlling the size of lipid droplets: lipid and protein factors. Curr Opin Cell Biol (2012) 1.30
Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex. EMBO J (2004) 1.28
Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities. Nucleic Acids Res (2003) 1.28
TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer. Cancer Res (2004) 1.27
Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad. Biochim Biophys Acta (2007) 1.27
Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem. Nature (2005) 1.22
Structural analysis of hydrophobins. Micron (2007) 1.20
Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity. J Biol Chem (2006) 1.20
Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein. J Biol Chem (2002) 1.20
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. EMBO J (2008) 1.19
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol (2013) 1.18
Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol (2014) 1.17
Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif. J Biol Chem (2004) 1.15
Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3. Biochem Biophys Res Commun (2004) 1.14
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proc Natl Acad Sci U S A (2006) 1.12
Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol (2008) 1.12
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH. J Biol Chem (2011) 1.11
Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses. PLoS Genet (2012) 1.11
Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4. EMBO J (2003) 1.09
The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2. J Biol Chem (2003) 1.09
Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. BMC Struct Biol (2007) 1.09
Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Mol Cell Biol (2011) 1.08
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. J Biol Chem (2003) 1.07
Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides? Trends Biochem Sci (2013) 1.07
GATA-1: one protein, many partners. Int J Biochem Cell Biol (2005) 1.07
Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Hum Mutat (2003) 1.06
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. J Biol Chem (2007) 1.05
Macromolecular NMR spectroscopy for the non-spectroscopist. FEBS J (2011) 1.04
Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. J Biol Chem (2010) 1.04
The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease. PLoS Negl Trop Dis (2009) 1.04
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol Cell Biol (2006) 1.04
Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins. Angew Chem Int Ed Engl (2012) 1.03
The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components. Mol Microbiol (2002) 1.02
Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA. J Mol Biol (2011) 1.01
LIM domain binding proteins 1 and 2 have different oligomeric states. J Mol Biol (2010) 1.00
A mechanism for Ikaros regulation of human globin gene switching. Br J Haematol (2008) 1.00
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proc Natl Acad Sci U S A (2011) 1.00
Two-timing zinc finger transcription factors liaising with RNA. Trends Biochem Sci (2012) 0.99
KAI1 promoter activity is dependent on p53, junB and AP2: evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells. Oncogene (2005) 0.99
Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification. J Biol Chem (2011) 0.98
Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia. Ann N Y Acad Sci (2005) 0.97
Stabilization of a binary protein complex by intein-mediated cyclization. Protein Sci (2006) 0.96
Crystal and solution structures of a superantigen from Yersinia pseudotuberculosis reveal a jelly-roll fold. Structure (2004) 0.96
Impaired B cell development in the absence of Krüppel-like factor 3. J Immunol (2011) 0.95
Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12. Proteins (2008) 0.95
The structure of the zinc finger domain from human splicing factor ZNF265 fold. J Biol Chem (2003) 0.95