Published in Mol Cell Biol on February 01, 2005
Mammalian Krüppel-like factors in health and diseases. Physiol Rev (2010) 4.09
A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo. J Biol Chem (2008) 1.72
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol Cell Biol (2007) 1.69
Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex. Mol Cell Biol (2007) 1.49
Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells. Mol Cell Biol (2007) 1.45
Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis. Mol Cell Biol (2008) 1.36
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx. Proc Natl Acad Sci U S A (2005) 1.33
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol (2013) 1.18
SUMOylation regulates nuclear localization of Krüppel-like factor 5. J Biol Chem (2008) 1.18
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence. Mol Cell Biol (2006) 1.12
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol Cell Biol (2006) 1.04
Epithelial sodium channel (ENaC) is multi-ubiquitinated at the cell surface. Biochem J (2007) 0.97
SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancy. Nucleic Acids Res (2007) 0.95
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo. Mol Cell Biol (2012) 0.93
A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4. J Biol Chem (2010) 0.92
Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5. PLoS One (2011) 0.92
KLF3 regulates muscle-specific gene expression and synergizes with serum response factor on KLF binding sites. Mol Cell Biol (2010) 0.90
ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. PLoS Genet (2013) 0.87
Sumoylation of Krüppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation. J Biol Chem (2013) 0.87
Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP). J Biol Chem (2010) 0.87
Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2). Diabetes (2013) 0.86
CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking. J Biol Chem (2013) 0.83
GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J Biol Chem (2010) 0.83
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster. BMC Bioinformatics (2010) 0.83
SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons. Channels (Austin) (2013) 0.82
Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation. J Biol Chem (2013) 0.81
SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4. PLoS One (2012) 0.80
Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity. J Biol Chem (2015) 0.78
SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation. PLoS One (2012) 0.78
Arabidopsis HFR1 is a potential nuclear substrate regulated by the Xanthomonas type III effector XopD(Xcc8004). PLoS One (2015) 0.78
Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells. BMC Mol Biol (2014) 0.76
Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3). J Biol Chem (2016) 0.76
Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain. Nucleic Acids Res (2015) 0.75
Epigenetic dysfunctional diseases and therapy for infection and inflammation. Biochim Biophys Acta (2016) 0.75
Krüppel-like factors in mammalian stem cells and development. Development (2017) 0.75
Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program. Mol Cell (2017) 0.75
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature (2002) 14.63
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Themes and variations on ubiquitylation. Nat Rev Mol Cell Biol (2001) 8.68
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell (1998) 6.62
Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature (2003) 6.48
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature (2003) 6.31
The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell (2002) 5.80
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev (2001) 5.79
Sp1- and Krüppel-like transcription factors. Genome Biol (2003) 5.42
SUMO--nonclassical ubiquitin. Annu Rev Cell Dev Biol (2000) 5.37
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3. J Biol Chem (2000) 5.30
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J Biol Chem (2001) 5.04
How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol (2003) 4.90
An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell (2001) 4.81
Nuclear and unclear functions of SUMO. Nat Rev Mol Cell Biol (2003) 4.76
SUMO, ubiquitin's mysterious cousin. Nat Rev Mol Cell Biol (2001) 4.65
A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells. Anal Biochem (1986) 4.60
The polycomb protein Pc2 is a SUMO E3. Cell (2003) 3.91
Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor. Nature (1989) 3.76
A tale of three fingers: the family of mammalian Sp/XKLF transcription factors. Nucleic Acids Res (1999) 3.68
P300 transcriptional repression is mediated by SUMO modification. Mol Cell (2003) 3.67
Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol Cell (2001) 3.56
Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J (1988) 3.34
Modification with SUMO. A role in transcriptional regulation. EMBO Rep (2003) 3.25
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol Cell Biol (2002) 3.25
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission. Curr Biol (2004) 3.21
A superfamily of protein tags: ubiquitin, SUMO and related modifiers. Trends Biochem Sci (2003) 3.19
Histone sumoylation is associated with transcriptional repression. Proc Natl Acad Sci U S A (2003) 3.18
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators. EMBO J (1998) 3.06
SUMO promotes HDAC-mediated transcriptional repression. Mol Cell (2004) 2.97
SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Mol Cell (2002) 2.93
SUMO: ligases, isopeptidases and nuclear pores. Trends Biochem Sci (2003) 2.92
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). Proc Natl Acad Sci U S A (2000) 2.79
Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO J (2002) 2.77
Ubch9 conjugates SUMO but not ubiquitin. FEBS Lett (1997) 2.73
c-Jun and p53 activity is modulated by SUMO-1 modification. J Biol Chem (2000) 2.71
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J (2002) 2.56
Two different virus-inducible elements are required for human beta-interferon gene regulation. EMBO J (1989) 2.50
Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. Cell (2003) 2.42
Transcription factor Sp3 is silenced through SUMO modification by PIAS1. EMBO J (2002) 2.41
Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells. Mol Cell Biol (1996) 2.31
Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity. Mol Cell (2003) 2.23
PIAS/SUMO: new partners in transcriptional regulation. Cell Mol Life Sci (2003) 2.15
SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities. J Biol Chem (2002) 1.99
C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Mol Cell Biol (1999) 1.97
PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription. J Biol Chem (2002) 1.90
A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy. Mol Cell Biol (2000) 1.90
The CtBP family: enigmatic and enzymatic transcriptional co-repressors. Bioessays (2001) 1.86
SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4. J Biol Chem (2003) 1.82
Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport. Traffic (2002) 1.82
Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity. J Biol Chem (2002) 1.71
Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy. Proc Natl Acad Sci U S A (2003) 1.60
Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding. Mol Cell (2003) 1.57
ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation. Mol Endocrinol (2000) 1.55
Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation. J Biol Chem (2002) 1.54
SUMO: of branched proteins and nuclear bodies. Oncogene (2001) 1.52
A synergy control motif within the attenuator domain of CCAAT/enhancer-binding protein alpha inhibits transcriptional synergy through its PIASy-enhanced modification by SUMO-1 or SUMO-3. J Biol Chem (2003) 1.52
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1. Proc Natl Acad Sci U S A (1999) 1.45
The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression. J Biol Chem (2002) 1.40
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. J Biol Chem (2002) 1.36
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. Biochem J (2002) 1.33
The histone deacetylase 9 gene encodes multiple protein isoforms. J Biol Chem (2003) 1.32
Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities. J Biol Chem (2000) 1.28
hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci. EMBO J (2003) 1.28
How to activate a damage-tolerant polymerase: consequences of PCNA modifications by ubiquitin and SUMO. Cell Cycle (2004) 1.21
SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling. J Biol Chem (2002) 1.20
Repression of Smad4 transcriptional activity by SUMO modification. Biochem J (2004) 1.17
The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2. J Biol Chem (2003) 1.09
Modification with SUMO. A role in transcriptional regulation. EMBO Rep (2003) 3.25
Protein interactions: is seeing believing? Trends Biochem Sci (2007) 2.85
Sticky fingers: zinc-fingers as protein-recognition motifs. Trends Biochem Sci (2007) 2.47
Krüppel-like transcription factors: a functional family. Int J Biochem Cell Biol (2007) 2.31
A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo. J Biol Chem (2008) 1.72
Salicylate induced tinnitus: behavioral measures and neural activity in auditory cortex of awake rats. Hear Res (2006) 1.67
Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells. Mol Cell Biol (2007) 1.45
Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Mol Cell Biol (2003) 1.44
Engineering a protein scaffold from a PHD finger. Structure (2003) 1.42
Functional cross-antagonism between transcription factors FLI-1 and EKLF. Mol Cell Biol (2003) 1.42
Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis. Mol Cell Biol (2008) 1.36
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
Human KLF17 is a new member of the Sp/KLF family of transcription factors. Genomics (2006) 1.31
Controlling the size of lipid droplets: lipid and protein factors. Curr Opin Cell Biol (2012) 1.30
Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities. Nucleic Acids Res (2003) 1.28
Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad. Biochim Biophys Acta (2007) 1.27
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol (2013) 1.18
Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor. Genome Biol (2014) 1.17
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction. Proc Natl Acad Sci U S A (2005) 1.10
The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2. J Biol Chem (2003) 1.09
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. J Biol Chem (2003) 1.07
Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides? Trends Biochem Sci (2013) 1.07
Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Hum Mutat (2003) 1.06
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. J Biol Chem (2007) 1.05
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol Cell Biol (2006) 1.04
A mechanism for Ikaros regulation of human globin gene switching. Br J Haematol (2008) 1.00
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proc Natl Acad Sci U S A (2011) 1.00
Two-timing zinc finger transcription factors liaising with RNA. Trends Biochem Sci (2012) 0.99
KAI1 promoter activity is dependent on p53, junB and AP2: evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells. Oncogene (2005) 0.99
Impaired B cell development in the absence of Krüppel-like factor 3. J Immunol (2011) 0.95
PU.1 and Haematopoietic Cell Fate: Dosage Matters. Int J Cell Biol (2011) 0.94
Diminished cortical inhibition in an aging mouse model of chronic tinnitus. J Neurosci (2012) 0.94
The Ikaros family protein Eos associates with C-terminal-binding protein corepressors. Eur J Biochem (2002) 0.94
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo. Mol Cell Biol (2012) 0.93
Solution structure of the THAP domain from Caenorhabditis elegans C-terminal binding protein (CtBP). J Mol Biol (2006) 0.92
Protein-protein interactions: analysis of a false positive GST pulldown result. Proteins (2011) 0.92
NMR structure of the human Mediator MED25 ACID domain. J Struct Biol (2010) 0.92
Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU.1. J Biol Chem (2006) 0.92
Activation and repression of interleukin-12 p40 transcription by erythroid Kruppel-like factor in macrophages. J Biol Chem (2004) 0.92
KLF3 regulates muscle-specific gene expression and synergizes with serum response factor on KLF binding sites. Mol Cell Biol (2010) 0.90
A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. Structure (2002) 0.89
Characterization of the conserved interaction between GATA and FOG family proteins. J Biol Chem (2002) 0.89
The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain. J Biol Chem (2011) 0.89
The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF). IUBMB Life (2011) 0.89
Holding Tight: Cell Junctions and Cancer Spread. Trends Cancer Res (2012) 0.89
A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3. J Biol Chem (2004) 0.89
A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP. FEBS J (2006) 0.89
Homo- and heterodimerization in transcriptional regulation. Adv Exp Med Biol (2012) 0.88
The Caenorhabditis elegans protein CTBP-1 defines a new group of THAP domain-containing CtBP corepressors. J Mol Biol (2007) 0.87
Identification of regulatory regions within the KAI1 promoter: a role for binding of AP1, AP2 and p53. Gene (2003) 0.87
ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. PLoS Genet (2013) 0.87
Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor. Nucleic Acids Res (2013) 0.86
Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2). Diabetes (2013) 0.86
New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. J Biol Chem (2013) 0.85
C-terminal binding protein: A metabolic sensor implicated in regulating adipogenesis. Int J Biochem Cell Biol (2011) 0.85
Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). Blood (2011) 0.84
Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers. Biochemistry (2004) 0.84
A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden. Am J Hum Genet (2013) 0.84
GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J Biol Chem (2010) 0.83
Purification of SUMO-1 modified IκBα and complex formation with NF-κB. Protein Expr Purif (2011) 0.81
Plasmodium falciparum inhibitor-3 homolog increases protein phosphatase type 1 activity and is essential for parasitic survival. J Biol Chem (2011) 0.80
The C-terminal domain of Eos forms a high order complex in solution. J Biol Chem (2003) 0.79
Structural insights into ChpT, an essential dimeric histidine phosphotransferase regulating the cell cycle in Caulobacter crescentus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.79
Solution structure of the N-terminal transactivation domain of ERM modified by SUMO-1. Biochem Biophys Res Commun (2010) 0.79
Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting. Structure (2005) 0.78
The coactivator activator CoAA regulates PEA3 group member transcriptional activity. Biochem J (2011) 0.78
Mutual repression of transcriptional activation between the ETS-related factor ERG and estrogen receptor. Oncogene (2003) 0.77
Homeodomain interacting protein kinase (HPK-1) is required in the soma for robust germline proliferation in C. elegans. Dev Dyn (2013) 0.77
Hls5 regulated erythroid differentiation by modulating GATA-1 activity. Blood (2007) 0.76
Lack of association of a spontaneous mutation of the Chrm2 gene with behavioral and physiologic phenotypic differences in inbred mice. Comp Med (2010) 0.75
Cellular Reprogramming toward the Erythroid Lineage. Int J Cell Biol (2011) 0.75
Signal transduction by BvgS sensor kinase. BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY. J Biol Chem (2015) 0.75