Published in BMC Physiol on January 12, 2005
Muscle KATP channels: recent insights to energy sensing and myoprotection. Physiol Rev (2010) 2.06
Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1. Circ Res (2008) 1.98
Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes. Heart Rhythm (2010) 1.89
Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8. Heart Rhythm (2011) 1.87
Hydrogen sulphide and angiogenesis: mechanisms and applications. Br J Pharmacol (2011) 1.63
The host response to sepsis and developmental impact. Pediatrics (2010) 1.62
Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proc Natl Acad Sci U S A (2009) 1.28
Differential K(ATP) channel pharmacology in intact mouse heart. J Mol Cell Cardiol (2009) 1.26
KATP channels and cardiovascular disease: suddenly a syndrome. Circ Res (2013) 1.23
PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors. Am J Physiol Regul Integr Comp Physiol (2007) 1.22
Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms. J Physiol (2006) 1.22
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol (2006) 1.22
Cardiac sarcolemmal K(ATP) channels: Latest twists in a questing tale! J Mol Cell Cardiol (2009) 1.17
Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress. J Mol Cell Cardiol (2007) 1.13
Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activity. J Mol Cell Cardiol (2007) 1.12
Ankyrin-B regulates Kir6.2 membrane expression and function in heart. J Biol Chem (2010) 1.09
A short motif in Kir6.1 consisting of four phosphorylation repeats underlies the vascular KATP channel inhibition by protein kinase C. J Biol Chem (2007) 1.03
Molecular basis and structural insight of vascular K(ATP) channel gating by S-glutathionylation. J Biol Chem (2011) 1.00
Endosomal KATP channels as a reservoir after myocardial ischemia: a role for SUR2 subunits. Am J Physiol Heart Circ Physiol (2010) 0.98
α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion. Am J Physiol Endocrinol Metab (2010) 0.98
PKA-dependent activation of the vascular smooth muscle isoform of KATP channels by vasoactive intestinal polypeptide and its effect on relaxation of the mesenteric resistance artery. Biochim Biophys Acta (2007) 0.98
Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels. J Physiol (2005) 0.95
Expression of inwardly rectifying potassium channel subunits in native human retinal pigment epithelium. Exp Eye Res (2008) 0.94
Molecular biology of K(ATP) channels and implications for health and disease. IUBMB Life (2009) 0.93
Heterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated disk. J Biol Chem (2012) 0.90
Sulfonylurea receptor 1 subunits of ATP-sensitive potassium channels and myocardial ischemia/reperfusion injury. Trends Cardiovasc Med (2009) 0.88
Subsecond regulation of striatal dopamine release by pre-synaptic KATP channels. J Neurochem (2011) 0.84
Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel. Circ Res (2011) 0.84
HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels. J Mol Cell Cardiol (2010) 0.84
Dystrophin is required for the normal function of the cardio-protective K(ATP) channel in cardiomyocytes. PLoS One (2011) 0.83
Cardiac Mechano-Gated Ion Channels and Arrhythmias. Circ Res (2016) 0.82
KATP Channels in the Cardiovascular System. Physiol Rev (2016) 0.82
Cardiac specific ATP-sensitive K+ channel (KATP) overexpression results in embryonic lethality. J Mol Cell Cardiol (2012) 0.81
Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation. Am J Physiol Heart Circ Physiol (2010) 0.81
Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart. Acta Physiol (Oxf) (2007) 0.80
Natriuretic peptides modulate ATP-sensitive K(+) channels in rat ventricular cardiomyocytes. Basic Res Cardiol (2014) 0.80
The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits. J Physiol (2007) 0.80
PPARgamma and Agonists against Cancer: Rational Design of Complementation Treatments. PPAR Res (2008) 0.78
Measuring and evaluating the role of ATP-sensitive K+ channels in cardiac muscle. J Mol Cell Cardiol (2012) 0.78
The KCNJ8-S422L variant previously associated with J-wave syndromes is found at an increased frequency in Ashkenazi Jews. Eur J Hum Genet (2013) 0.78
A gain-of-function I(K-ATP) mutation and its role in sudden cardiac death associated with J-wave syndromes. Heart Rhythm (2010) 0.77
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Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis. Viruses (2009) 0.75
Molecular analysis of ATP-sensitive K⁺ channel subunits expressed in mouse vas deferens myocytes. Br J Pharmacol (2014) 0.75
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo. Br J Pharmacol (2006) 0.75
An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging. Front Pharmacol (2016) 0.75
Functional roles of KATP channel subunits in metabolic inhibition. J Mol Cell Cardiol (2013) 0.75
Effect of tobacco smoke on hydrogen sulfide-induced rat thoracic aorta relaxation. Braz J Med Biol Res (2017) 0.75
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Octameric stoichiometry of the KATP channel complex. J Gen Physiol (1997) 3.48
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Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. Proc Natl Acad Sci U S A (1998) 3.11
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Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1. Nat Med (2002) 2.45
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Molecular composition of mitochondrial ATP-sensitive potassium channels probed by viral Kir gene transfer. J Mol Cell Cardiol (2000) 1.88
Distribution of Kir6.0 and SUR2 ATP-sensitive potassium channel subunits in isolated ventricular myocytes. J Mol Cell Cardiol (2003) 1.85
Comparison of fixation protocols for adherent cultured cells applied to a GFP fusion protein of the epidermal growth factor receptor. Cytometry (1999) 1.77
Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondria. J Biol Chem (1992) 1.72
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The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle. J Physiol (1996) 1.50
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Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells. Circ Res (1998) 1.39
Disruption of Sur2-containing K(ATP) channels enhances insulin-stimulated glucose uptake in skeletal muscle. Proc Natl Acad Sci U S A (2001) 1.38
A mechanism for ATP-sensitive potassium channel diversity: Functional coassembly of two pore-forming subunits. Proc Natl Acad Sci U S A (2001) 1.31
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Adenosine potentiates flow-induced dilation of coronary arterioles by activating KATP channels in endothelium. Am J Physiol (1995) 1.13
K ATP channels of primary human coronary artery endothelial cells consist of a heteromultimeric complex of Kir6.1, Kir6.2, and SUR2B subunits. J Mol Cell Cardiol (2004) 1.08
Differential expression of Kir6.1 and SUR2B mRNAs in the vasculature of various tissues in rats. J Membr Biol (2003) 1.04
Heterogeneous populations of K+ channels mediate EDRF release to flow but not agonists in rabbit aorta. Am J Physiol (1994) 1.03
Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts. FEBS Lett (2003) 0.98
Endothelial ATP-sensitive potassium channels mediate coronary microvascular dilation to hyperosmolarity. Am J Physiol (1997) 0.98
Potassium channels in the vasculature. Curr Opin Nephrol Hypertens (1998) 0.98
A novel K(ATP) current in cultured neonatal rat atrial appendage cardiomyocytes. Circ Res (1999) 0.95
ATP-sensitive potassium channels in capillaries isolated from guinea-pig heart. J Physiol (2000) 0.93
Myocardial ischemia induces differential regulation of KATP channel gene expression in rat hearts. J Clin Invest (1997) 0.92
Coronary arteriolar dilation to acidosis: role of ATP-sensitive potassium channels and pertussis toxin-sensitive G proteins. Circulation (1999) 0.91
Reciprocal regulation of expression of pore-forming KATP channel genes by hypoxia. Mol Cell Biochem (2001) 0.89
Channel activators regulate ATP-sensitive potassium channel (KIR6.1) expression in chick cardiomyocytes. FEBS Lett (1997) 0.85
Specific antagonism by glibenclamide of negative inotropic effects of potassium channel openers in canine atrial muscle. Jpn J Pharmacol (1990) 0.80
Rapid whole-genome sequencing for genetic disease diagnosis in neonatal intensive care units. Sci Transl Med (2012) 5.16
Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1. Cell Metab (2008) 2.22
Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery. Am J Respir Cell Mol Biol (2002) 2.06
Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1. Circ Res (2008) 1.98
Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity. Circ Res (2011) 1.97
Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells. Proc Natl Acad Sci U S A (2005) 1.91
Retracted The large-conductance Ca2+-activated K+ channel is essential for innate immunity. Nature (2004) 1.85
Novel insights into hydrogen sulfide--mediated cytoprotection. Antioxid Redox Signal (2010) 1.79
PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells. Am J Physiol Cell Physiol (2005) 1.56
Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells. Mol Cell (2006) 1.55
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations. J Am Coll Cardiol (2005) 1.40
Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J Biol Chem (2012) 1.40
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells. J Physiol (2006) 1.36
In situ maleimide bridging of disulfides and a new approach to protein PEGylation. Bioconjug Chem (2011) 1.33
Sarcolemmal ATP-sensitive K(+) channels control energy expenditure determining body weight. Cell Metab (2010) 1.31
The glycolytic enzymes, glyceraldehyde-3-phosphate dehydrogenase, triose-phosphate isomerase, and pyruvate kinase are components of the K(ATP) channel macromolecular complex and regulate its function. J Biol Chem (2005) 1.30
The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1. Mol Cell Biol (2005) 1.26
Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. J Physiol (2007) 1.24
Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study. Eur Heart J (2012) 1.24
Cysteine-674 of the sarco/endoplasmic reticulum calcium ATPase is required for the inhibition of cell migration by nitric oxide. Arterioscler Thromb Vasc Biol (2007) 1.23
SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart. Dev Cell (2009) 1.23
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol (2006) 1.22
Monitoring changes in membrane phosphatidylinositol 4,5-bisphosphate in living cells using a domain from the transcription factor tubby. J Physiol (2008) 1.19
Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis. Proc Natl Acad Sci U S A (2011) 1.19
Transgenic expression of a dominant negative K(ATP) channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion. FASEB J (2007) 1.19
Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics. J Biol Chem (2005) 1.18
Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia. J Mol Cell Cardiol (2010) 1.15
Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart. Pediatr Res (2005) 1.14
Vascular oxidative stress: the common link in hypertensive and diabetic vascular disease. J Cardiovasc Pharmacol (2010) 1.13
The molecular composition of K(ATP) channels in human pulmonary artery smooth muscle cells and their modulation by growth. Am J Respir Cell Mol Biol (2002) 1.12
Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1). Cardiovasc Res (2005) 1.11
Multisite phosphorylation mechanism for protein kinase A activation of the smooth muscle ATP-sensitive K+ channel. Circ Res (2004) 1.10
K ATP channels of primary human coronary artery endothelial cells consist of a heteromultimeric complex of Kir6.1, Kir6.2, and SUR2B subunits. J Mol Cell Cardiol (2004) 1.08
Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells. Mol Cell Biol (2006) 1.08
Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells. J Physiol (2008) 1.06
Noncoding RNA expression in myocardium from infants with tetralogy of Fallot. Circ Cardiovasc Genet (2012) 1.05
Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation (2008) 1.05
Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1. Mol Biol Cell (2005) 1.03
Assembly limits the pharmacological complexity of ATP-sensitive potassium channels. J Biol Chem (2002) 1.01
Mechanistic basis for the pathogenesis of long QT syndrome associated with a common splicing mutation in KCNQ1 gene. J Mol Cell Cardiol (2007) 1.01
PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. Pflugers Arch (2007) 1.00
Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. Circ Arrhythm Electrophysiol (2011) 1.00
Mutation site dependent variability of cardiac events in Japanese LQT2 form of congenital long-QT syndrome. Circ J (2008) 0.99
Endosomal KATP channels as a reservoir after myocardial ischemia: a role for SUR2 subunits. Am J Physiol Heart Circ Physiol (2010) 0.98
Characterization of a binding site for anionic phospholipids on KCNQ1. J Biol Chem (2010) 0.98
In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells. Stem Cell Rev (2011) 0.97
Ethical considerations associated with clinical use of next-generation sequencing in children. J Pediatr (2011) 0.97
Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability. PLoS One (2013) 0.95
The Role of Inhibitory G Proteins and Regulators of G Protein Signaling in the in vivo Control of Heart Rate and Predisposition to Cardiac Arrhythmias. Front Physiol (2012) 0.95
IP receptor-dependent activation of PPARgamma by stable prostacyclin analogues. Biochem Biophys Res Commun (2007) 0.95
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The role of inhibitory heterotrimeric G proteins in the control of in vivo heart rate dynamics. Am J Physiol Regul Integr Comp Physiol (2008) 0.95
Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3. Circ Res (2012) 0.95
Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome. Hum Mutat (2009) 0.95
NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Dev Biol (2012) 0.94
Activation of presynaptic GABAA receptors increases spontaneous glutamate release onto noradrenergic neurons of the rat locus coeruleus. Brain Res (2005) 0.94
AMP-activated protein kinase connects cellular energy metabolism to KATP channel function. J Mol Cell Cardiol (2011) 0.94
HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes. Pflugers Arch (2010) 0.93
The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor. J Biol Chem (2003) 0.93
Cardiac ATP-sensitive K+ channel associates with the glycolytic enzyme complex. FASEB J (2011) 0.92
Exercise-induced expression of cardiac ATP-sensitive potassium channels promotes action potential shortening and energy conservation. J Mol Cell Cardiol (2011) 0.92
Dimerization is crucial for the function of the Na+/H+ exchanger NHE1. Biochemistry (2006) 0.91
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. FASEB J (2011) 0.91
Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia. Circ Arrhythm Electrophysiol (2010) 0.90
Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice. J Mol Cell Cardiol (2009) 0.90
Posttraumatic stress disorder in children after cardiac surgery. J Pediatr (2004) 0.90
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Alpha1-adrenoceptor-mediated breakdown of phosphatidylinositol 4,5-bisphosphate inhibits pinacidil-activated ATP-sensitive K+ currents in rat ventricular myocytes. Circ Res (2002) 0.89
Sorcin regulates excitation-contraction coupling in the heart. J Biol Chem (2003) 0.89
Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K+ channels. Proc Natl Acad Sci U S A (2003) 0.89
Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior. J Biol Chem (2009) 0.89
Complex ABCC8 DNA variations in congenital hyperinsulinism: lessons from functional studies. Clin Endocrinol (Oxf) (2007) 0.89
Structural requirements of membrane phospholipids for M-type potassium channel activation and binding. J Biol Chem (2012) 0.89
The intracellular localization and function of the ATP-sensitive K+ channel subunit Kir6.1. J Membr Biol (2010) 0.89
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Developmental expression of NCS-1 (frequenin), a regulator of Kv4 K+ channels, in mouse heart. Pediatr Res (2003) 0.88
Sulfonylurea receptor 1 subunits of ATP-sensitive potassium channels and myocardial ischemia/reperfusion injury. Trends Cardiovasc Med (2009) 0.88
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Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? Circ Res (2003) 0.88
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Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle. Am J Physiol Cell Physiol (2004) 0.87
Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines. Biochim Biophys Acta (2014) 0.86
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